Efficacy, Safety, and Survival Rates of IOP-Lowering Effect of Phacoemulsification Alone Or Combined with Canaloplasty in Glaucoma Patients
ORIGINAL STUDY Efficacy, Safety, and Survival Rates of IOP-lowering Effect of Phacoemulsification Alone or Combined With Canaloplasty in Glaucoma Patients Stella N. Arthur, MD, MSPH,*w Louis B. Cantor, MD,* Darrell WuDunn, MD, PhD,* Guruprasad R. Pattar, MD,* Yara Catoira-Boyle, MD,* Linda S. Morgan, CCRC, COA,* and Joni S. Hoop, CCRC, COA* Conclusions: A combination of canaloplasty with phaco results in a Purpose: To evaluate efficacy and survival rates of intraocular decreased number of glaucoma medications and increased survival pressure (IOP)-lowering effect obtained with phacoemulsification rate of IOP-lowering effect compared with phaco alone. (phaco) alone or in combination with canaloplasty (PCP) in patients with open-angle glaucoma (OAG). Key Words: phacoemulsification, canaloplasty, glaucoma Methods: Retrospective chart review of consecutive cases at the (J Glaucoma 2013;00:000–000) Department of Ophthalmology, Indiana University. Visual acuity (VA), IOP, number of medications (Meds), failures, and survival rates of IOP-lowering effect were analyzed. Inclusion criteria were: patients older than 18 years with OAG and cataract. Exclusion umerous studies demonstrate that phacoemulsification criteria were: no light perception vision, prior glaucoma surgery, N(phaco) may produce long-term reduction of intra- 1,2 chronic uveitis, angle-closure glaucoma, and advanced-stage or ocular pressure (IOP) in subjects without glaucoma, end-stage OAG. Failure criteria were: IOP > 21 mm Hg or <20% patients with pseudoexfoliation syndrome,3,4 or glaucoma reduction, IOP < 6 mm Hg, further glaucoma surgeries, and loss of patients.5–8 The effect is thought to be mediated by 3 major light perception vision. mechanisms: hyposecretion of aqueous humor due to Results: Thirty-seven patients underwent phaco and 32 patients had production of free radicals or partial ciliary body detach- PCP.
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