JULIA A. KALOW

Department of Chemistry 2145 Sheridan Road [email protected] Evanston, IL 60208-3113 http://sites.northwestern.edu/kalowlab/

PROFESSIONAL EXPERIENCE

Assistant Professor of Chemistry, Northwestern University 2016–present

Ruth L. Kirschstein Postdoctoral Fellow, Massachusetts Institute of Technology 2013–2016 Advisor: Professor Timothy M. Swager • Developed an efficient synthesis of telechelic P3HT and a versatile strategy to prepare miktoarm branched based on ring-opening metathesis polymerization. • Studied the self-assembly of novel architectures of conjugated polymers in solution and in bulk. • Collaborated with a team of researchers studying tunable complex emulsions and applied these emulsions to enzyme sensing.

Graduate Research Assistant, , Department of Chemistry 2008–2013 Advisor: Professor Abigail G. Doyle Thesis title: Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source: Development and mechanistic investigations • Initiated a program in asymmetric catalytic nucleophilic fluorination in the Doyle lab and introduced the use of benzoyl fluoride as a latent HF source for C–F bond formation. • Discovered key mechanistic insights into cooperative catalysis in the fluorination reactions that have led to additional projects, including selective radiofluorination.

Intern, Merck Research Laboratories, Medicinal Chemistry, Boston, MA Summer 2007 • Investigated metal-catalyzed trifluoromethylation methods (with Dr. Jed Hubbs).

Undergraduate Researcher, , Department of Chemistry 2005–2008 Advisor: Professor James L. Leighton • Participated in studies toward the synthesis of isocyclocitrinol A (with Dr. Arash Soheili). • Developed an enantioselective imino-Nazarov rearrangement (with Dr. Gregory Notte).

EDUCATION

Princeton University, Princeton, NJ 2008–2013 Ph.D., Chemistry • Cumulative GPA: 4.00/4.00

Columbia University, New York, NY 2004–2008 B.A. with honors, Chemistry and Creative Writing, summa cum laude • Cumulative GPA: 4.09/4.30; major GPA: 4.14/4.30 Julia Kalow: curriculum vitae 2

EXTERNAL FUNDING

NIH NRSA F32: “A Conjugated Fluorogenic Probe for Inorganic Polyphosphate” 2013–2016

INTERNAL FUNDING

Lurie Cancer Center, American Cancer Society Institutional Research Grant: “Enabling Visible/NIR Photocontrol of 4D Biomaterials: Towards Tissue-Engineered Technologies for Cancer Research” 2017

AWARDS AND HONORS

Rising Stars in Chemistry Symposium, invitee, 2015 Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship 2013–present Charlotte Elizabeth Procter Honorific Fellowship, Princeton University 2012–2013 ACS Division of Organic Chemistry Graduate Fellowship, sponsored by Pfizer 2011–2012 Third-Year Seminar Award, Department of Chemistry, Princeton University 2011 Bristol-Myers Squibb Endowed Fellowship in Synthetic Organic Chemistry 2010 National Science Foundation Pre-Doctoral Fellowship 2008–2011 Hugh Scott Taylor Award, Princeton University 2008–2012 Salutatorian, Columbia College 2008 Karen Osney Brownstein Prize for Creative Writing, Columbia College 2008 Phi Beta Kappa, Columbia College 2007 Barry M. Goldwater Scholarship, Honorable Mention 2007 Pfizer Summer Undergraduate Research Fellowship 2006

TEACHING EXPERIENCE

Polymer Chemistry Winter 2017 Northwestern University, Department of Chemistry (7 graduate, 5 undergraduate students) • Average rating for course: tbd; average rating for instructor: tbd

Organic Reaction Mechanisms Fall 2016 Northwestern University, Department of Chemistry (14 graduate, 4 undergraduate students) • Average rating for course: 4.89/6.00; average rating for instructor: 4.83/6.00

Preceptor, Organic Chemistry I Fall 2009 Princeton University, Department of Chemistry (80 students, 3 sections) • Average rating for instructor: 3.98/5.00

Teaching Assistant, Intensive General Chemistry Laboratory Spring 2007–2008 Columbia University, Department of Chemistry (12 students, 2 sections)

Peer-Led Learning Center Fall 2006 Columbia University, Department of Chemistry

Julia Kalow: curriculum vitae 3

INTERNAL SERVICE AND AFFILIATIONS

Qualifying exam committee member (2017 (6)) 2017– Graduate admissions committee 2016– Member, International Institute of Nanotechnology 2016–

EXTERNAL SERVICE AND AFFILIATIONS

Mentor, NSF Future Faculty Workshop for women and underrepresented minorities, Case Western Reserve University, Cleveland, OH 2017 Panel reviewer, NSF CHE 2017 Co-organizer, Chicago Organic Symposium 2017 Session chair, RSC Polymer Chemistry Symposium, ACS San Francisco 2017 Session chair, PMSE Young Investigator Symposium, ACS San Francisco 2017 Session chair, ORGN Chemistry of Fullerenes, Carbon Nanotubes, and Graphene, ACS Philadelphia 2016 Discussion leader, Gordon Research Seminar in Polymer Chemistry 2015 Reviewer (Macromolecules, ACS Macro Letters, Nature Chemistry) 2014–present Member, Materials Research Society 2014–present Contributor and team captain, SYNFACTS 2014 Member, American Chemical Society, Division of Organic Chemistry 2011–present Kalow Group outreach participation: National Chemistry Week hands-on demonstration of low- cost sensors (Loyola University, October 2016), high school science fair judges (December 2016)

MENTORSHIP

Graduate students: Xiaodi Wang (2016–present), Joseph Accardo (2016–present), Eliot Woods (2016–present)

Postdoctoral scholars: Youlong Zhu (2016–2017)

Undergraduate students: Colin Clayton, (Northwestern ’18, 2016–present), Yan Fang (Northwestern ’19, 2016–present), Xinping He (Tianjin U. ’15, 2014-2015), Dana Schmitt (Princeton ’12, 2011-2012)

PUBLICATIONS (undergraduate co-authors are underlined) 1. Zarzar, L. D.; Kalow, J. A.; He, X.; Walish, J. J.; Swager, T. M. “Optical Visualization and Quantification of Enzyme Activity using Dynamic Droplet Lenses.” Proc. Natl. Acad. Sci. 2017, accepted. 2. Sha, S.-C.; Zhu, R.; Herbert, M.; Kalow, J. A.; Swager, T. M. “Chemical Warfare Simulant- Responsive Polymer Nanocomposites: Synthesis and Evaluation.” J. Poly. Sci. A Polym. Chem. 2017, accepted. • Invited contribution in honor of Bob Grubbs’ 75th birthday. Julia Kalow: curriculum vitae 4

3. Nagelberg, S.; Zarzar L. D.; Nicolas, N.; Subramanian, K.; Kalow, J. A.; Sresht, V.; Blankschtein, D.; Barbastathis, G.; Kreysing, M.; Swager, T. M.; Kolle, M. “Reconfigurable and Responsive Droplet-based Compound Micro-Lenses.” Nature Commun. 2017, 8, 14673. 4. Gray, E. E.; Nielsen, M. K.; Choquette, K. A.; Kalow, J. A.; Graham, T. J. A.; Doyle, A. G. “Nucleophilic (Radio)Fluorination of α-Diazocarbonyl Compounds Enabled by Copper- Catalyzed H–F Insertion.” J. Am. Chem. Soc. 2016, 138, 10802–10805. 5. Kalow, J. A.; Swager, T. M. “Synthesis of Miktoarm Branched Conjugated by ROMPing In and Out.” ACS Macro Lett. 2015, 4, 1229–1233. 6. Zarzar, L. D.; Sresht, V.; Sletten, E. M.; Kalow, J. A.; Blankschtein, D.; Swager, T. M. “Dynamic Reconfiguration of Complex Emulsions via Tunable Interfacial Tensions.” Nature 2015, 518, 520–524. • Featured in Chemical and Engineering News and MIT news.

7. Kalow, J. A.; Doyle, A. G. “34.9.2. b-Fluoro Alcohols (Update 2013).” Sci. Synth. 2013, 4, 417– 467. • Invited contribution. 8. Kalow, J. A.; Doyle, A. G. “Enantioselective fluoride ring opening of aziridines enabled by cooperative Lewis acid catalysis.” Tetrahedron 2013, 69, 5702–5709. • Invited paper for Tetrahedron Young Investigator Award Symposium-in-Print in honor of Melanie Sanford. • Highlighted in SYNFACTS (2013, Issue 9).

9. Kalow, J. A.; Schmitt, D. E.; Doyle, A. G. “Synthesis of β-Fluoroamines by Lewis Base Catalyzed Hydrofluorination of Aziridines.” J. Org. Chem. 2012, 77, 4177–4183. 10. Shaw, T. W.; Kalow, J. A.; Doyle, A. G. “Fluoride ring-opening kinetic resolution of terminal epoxides: preparation of (S)-2-fluoro-1-phenylethanol.” Org. Synth. 2012, 89, 9–18. 11. Kalow, J. A.; Doyle, A. G. “Mechanistic investigations of cooperative catalysis in the enantioselective fluorination of epoxides.” J. Am. Chem. Soc. 2011, 133, 16001–16012. • Highlighted in SYNFACTS (2011, Issue 12). 12. Kalow, J. A.; Doyle, A. G. “Enantioselective Ring Opening of Epoxides by Fluoride Anion Promoted by a Cooperative Dual-Catalyst System.” J. Am. Chem. Soc., 2010, 132, 3268–3269. • Highlighted in SYNFACTS (2010, Issue 6), SYNFORM (2010, Issue 7), and Org. Process Res. Dev. (“Some Items of Interest to Process R&D Chemists and Engineers”, 2010).

INVITED PRESENTATIONS Kalow, J. A. “Synthesis and Self-Assembly of Soft Materials for Biosensing.” Boston Symposium on Organic and Bioorganic Chemistry, Boston, MA, October 2015. Kalow, J. A. “Synthetic strategies for spatial control from the molecular to macro scale.” Rising Stars in Chemistry Symposium, University of Chicago, Chicago, IL, June 2015. Kalow, J. A.; Swager, T. M. “ROMPing in and out: synthesis and self-assembly of conjugated H- Julia Kalow: curriculum vitae 5 shaped polymers.” Polymer Day, MIT, Cambridge, MA, March 2015.

CONTRIBUTED PRESENTATIONS Kalow, J. A.; Swager, T. M. “ROMPing in and out: synthesis and self-assembly of conjugated H- shaped polymers.” 250th ACS National Meeting, POLY division (oral presentation), Boston, MA, August 2015. Kalow, J. A.; Zarzar, L. D.; He, X.; Swager, T. M. “Responsive responsive surfactants for biosensing with dynamic complex emulsions.” 250th ACS National Meeting, ORGN division (oral presentation), Boston, MA, August 2015. Kalow, J. A.; Zarzar, L. D.; He, X.; Swager, T. M. “Design and synthesis of responsive surfactants for dynamic complex emulsions.” Organic Reations & Processes Gordon Research Conference (poster), Lewiston, ME, July 2015. Kalow, J. A.; Swager, T. M. “ROMPing in and out: synthesis and self-assembly of conjugated H- shaped polymers.” Polymer Chemistry Gordon Research Conference and Symposium (poster), South Hadley, MA, June 2015. Kalow, J. A.; Swager, T. M. “H-shaped conjugated block copolymers: synthesis and self-assembly.” Materials Research Society National Meeting (poster), Boston, MA, December 2014. Kalow, J. A.; Graham, T. J.; Lambert, R. F.; Doyle, A. G. “New methods for asymmetric nucleophilic fluorination and radiofluorination.” National Organic Symposium (poster), Seattle, WA, June 2013. Kalow, J. A.; Doyle, A. G. “Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source.” 244th ACS National Meeting (oral presentation), Philadelphia, PA, August 2012. Kalow, J. A.; Doyle, A. G. “Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source.” ISACS7: Challenges in Organic Chemistry and Chemical Biology (poster), Edinburgh, UK, June 2012. Kalow, J. A.; Doyle. A. G. “Cooperative Catalysis in the Enantioselective Ring Opening of Epoxides and Aziridines by Fluoride Anion.” National Organic Symposium (poster), Princeton, NJ, June 2011. Kalow, J. A.; Doyle, A. G. “Enantioselective Ring Opening with Fluoride Anion Promoted by a Cooperative Dual-Catalyst System.” Pacifichem (poster), Honolulu, HI, December 2010.

PATENTS

T. M. Swager, E. D. Blankschtein, L. D. Zarzar, V. Sresht, E. M. Sletten, J. A. Kalow, “Compositions and methods for arranging colloid phases.” Filed 2014, US Provisional Patent: 62/073915.

T. M. Swager, E. D. Blankschtein, L. D. Zarzar, V. Sresht, E. M. Sletten, J. A. Kalow, “Compositions and methods for forming emulsions.” Filed 2014, US Provisional Patent: 62/073896.