JULIA A. KALOW

Department of Chemistry work: (847) 467-4972 2145 Sheridan Road [email protected] Evanston, IL 60208-3113 http://sites.northwestern.edu/kalowlab/

PROFESSIONAL EXPERIENCE

Assistant Professor of Chemistry, Northwestern University 2016–present • Research interests: chemistry, synthetic methodology, photochemistry, physical organic chemistry, , sustainable , organic materials

Ruth L. Kirschstein Postdoctoral Fellow, Massachusetts Institute of Technology 2013–2016 Advisor: Professor Timothy M. Swager • Developed an efficient synthesis of telechelic P3HT and a versatile strategy to prepare miktoarm branched polymers based on ring-opening metathesis polymerization. • Studied the self-assembly of novel architectures of conjugated polymers in solution and in bulk. • Designed responsive emulsions and developed strategies for the use of tunable complex emulsions in enzyme sensing.

Graduate Research Assistant, , Department of Chemistry 2008–2013 Advisor: Professor Abigail G. Doyle Thesis title: Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source: Development and mechanistic investigations • Initiated a program in asymmetric catalytic nucleophilic fluorination in the Doyle lab and introduced the use of benzoyl fluoride as a latent HF source for C–F bond formation. • Discovered key mechanistic insights into cooperative catalysis in the fluorination reactions that have led to additional projects, including selective radiofluorination.

Intern, Merck Research Laboratories, Medicinal Chemistry, Boston, MA Summer 2007 • Investigated metal-catalyzed trifluoromethylation methods (with Dr. Jed Hubbs).

Undergraduate Researcher, , Department of Chemistry 2005–2008 Advisor: Professor James L. Leighton • Participated in studies toward the synthesis of isocyclocitrinol A (with Dr. Arash Soheili). • Developed an enantioselective imino-Nazarov rearrangement (with Dr. Gregory Notte).

EDUCATION

Princeton University, Princeton, NJ 2008–2013 Ph.D., Chemistry • Cumulative GPA: 4.00/4.00

Columbia University, New York, NY 2004–2008 B.A. with honors, Chemistry and Creative Writing, summa cum laude • Cumulative GPA: 4.09/4.30; major GPA: 4.14/4.30

Julia Kalow: curriculum vitae 2

AWARDS AND HONORS

Searle Fellows Program, Searle Center for Advancing Learning and Teaching 2017-2018 3M Non-Tenured Faculty Award 2018 Thieme Chemistry Journal Award 2018 Young Investigator Award, Air Force Office of Scientific Research 2017 Rising Stars in Chemistry Symposium, invitee, 2015 Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship 2013–2016 Charlotte Elizabeth Procter Honorific Fellowship, Princeton University 2012–2013 ACS Division of Organic Chemistry Graduate Fellowship, sponsored by Pfizer 2011–2012 Third-Year Seminar Award, Department of Chemistry, Princeton University 2011 Bristol-Myers Squibb Endowed Fellowship in Synthetic Organic Chemistry 2010 National Science Foundation Pre-Doctoral Fellowship 2008–2011 Hugh Scott Taylor Award, Princeton University 2008–2012 Salutatorian, Columbia College 2008 Karen Osney Brownstein Prize for Creative Writing, Columbia College 2008 Phi Beta Kappa, Columbia College 2007 Barry M. Goldwater Scholarship, Honorable Mention 2007 Pfizer Summer Undergraduate Research Fellowship 2006

PUBLICATIONS (undergraduate co-authors are underlined) https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47976984/?sort=date&direction=descending Independent career 3. Accardo, J. V.; Kalow, J. A. “Reversibly Tuning Hydrogel Stiffness through Photocontrolled Dynamic Covalent Crosslinks.” Chem. Sci., 2018. [DOI:10.1039/C8SC02093K] 2. Ishibashi, J. S. A.; Kalow, J. A. “Vitrimeric Silicone Elastomers Enabled by Dynamic Meldrum’s Acid- Derived Crosslinks.” ACS Macro Lett., 2018, 7, 482–486. [DOI:10.1021/acsmacrolett.8b00166] 1. Wang, X.; Kalow, J. A. “Rapid aqueous photouncaging by red light.” Org. Lett., 2018, 20, 1716–1719. [DOI:10.1021/acs.orglett.8b00100] Mentored research 12. Zarzar, L. D.; Kalow, J. A.; He, X.; Walish, J. J.; Swager, T. M. “Optical Visualization and Quantification of Enzyme Activity using Dynamic Droplet Lenses.” Proc. Natl. Acad. Sci. 2017, 114, 3821–3825. 11. Sha, S.-C.; Zhu, R.; Herbert, M.; Kalow, J. A.; Swager, T. M. “Chemical Warfare Simulant-Responsive Polymer Nanocomposites: Synthesis and Evaluation.” J. Poly. Sci. A Polym. Chem. 2017, 55, 3034–3040. • Invited contribution in honor of Bob Grubbs’ 75th birthday. 10. Nagelberg, S.; Zarzar L. D.; Nicolas, N.; Subramanian, K.; Kalow, J. A.; Sresht, V.; Blankschtein, D.; Barbastathis, G.; Kreysing, M.; Swager, T. M.; Kolle, M. “Reconfigurable and Responsive Droplet-based Compound Micro-Lenses.” Nature Commun. 2017, 8, 14673. 9. Gray, E. E.; Nielsen, M. K.; Choquette, K. A.; Kalow, J. A.; Graham, T. J. A.; Doyle, A. G. “Nucleophilic (Radio)Fluorination of α-Diazocarbonyl Compounds Enabled by Copper-Catalyzed H–F Insertion.” J. Am. Chem. Soc. 2016, 138, 10802–10805. Julia Kalow: curriculum vitae 3

8. Kalow, J. A.; Swager, T. M. “Synthesis of Miktoarm Branched Conjugated by ROMPing In and Out.” ACS Macro Lett. 2015, 4, 1229–1233. 7. Zarzar, L. D.; Sresht, V.; Sletten, E. M.; Kalow, J. A.; Blankschtein, D.; Swager, T. M. “Dynamic Reconfiguration of Complex Emulsions via Tunable Interfacial Tensions.” Nature 2015, 518, 520–524. 11. Featured in Chemical and Engineering News and MIT news.

6. Kalow, J. A.; Doyle, A. G. “34.9.2. b-Fluoro Alcohols (Update 2013).” Sci. Synth. 2013, 4, 417–467. 12. Invited contribution. 5. Kalow, J. A.; Doyle, A. G. “Enantioselective fluoride ring opening of aziridines enabled by cooperative Lewis acid catalysis.” Tetrahedron 2013, 69, 5702–5709. • Invited paper for Tetrahedron Young Investigator Award Symposium-in-Print in honor of Melanie Sanford. • Highlighted in SYNFACTS (2013, Issue 9).

4. Kalow, J. A.; Schmitt, D. E.; Doyle, A. G. “Synthesis of β-Fluoroamines by Lewis Base Catalyzed Hydrofluorination of Aziridines.” J. Org. Chem. 2012, 77, 4177–4183. 3. Shaw, T. W.; Kalow, J. A.; Doyle, A. G. “Fluoride ring-opening kinetic resolution of terminal epoxides: preparation of (S)-2-fluoro-1-phenylethanol.” Org. Synth. 2012, 89, 9–18. 2. Kalow, J. A.; Doyle, A. G. “Mechanistic investigations of cooperative catalysis in the enantioselective fluorination of epoxides.” J. Am. Chem. Soc. 2011, 133, 16001–16012. • Highlighted in SYNFACTS (2011, Issue 12). 1. Kalow, J. A.; Doyle, A. G. “Enantioselective Ring Opening of Epoxides by Fluoride Anion Promoted by a Cooperative Dual-Catalyst System.” J. Am. Chem. Soc., 2010, 132, 3268–3269. • Highlighted in SYNFACTS (2010, Issue 6), SYNFORM (2010, Issue 7), and Org. Process Res. Dev. (“Some Items of Interest to Process R&D Chemists and Engineers”, 2010).

EXTERNAL FUNDING

3M Non-Tenured Faculty Award ($45,000/3 years): “Merging reactivity and properties: photocontrolled polymerizations and materials” 2018-2021 American Chemical Society Petroleum Research Fund ($110,000/2 years): “Visible light-promoted functionalization of coal-tar dyes: mechanism and synthetic utility” 2018-2020 Air Force Office of Scientific Research, Young Investigator Program ($450,000/3 years): “Merging reactivity and properties: photocontrolled synthesis of π-conjugated polymers” 2018-2021 Center for Sustainable Polymers (NSF Center for Chemical Innovation) Seed Grant ($75,000/1 year): “Photochemical Recycling: Photoactivated exchange of aromatic linkers for recyclable elastomers and thermosets” 2017-2018 NIH NRSA F32 ($151,926/3 years): “A Conjugated Polymer Fluorogenic Probe for Inorganic Polyphosphate” 2013–2016

INTERNAL FUNDING

Alumnae of Northwestern University ($2,500): grant to the Chicago Organic Symposium 2018 Lurie Cancer Center, American Cancer Society Institutional Research Grant ($30,000/1 year): “Enabling Visible/NIR Photocontrol of 4D Biomaterials: Towards Tissue-Engineered Technologies for Cancer Research” 2017 Julia Kalow: curriculum vitae 4

TEACHING EXPERIENCE

Organic Chemistry for Non-Majors Winter 2018 Northwestern University, Department of Chemistry (130 undergraduate students) • 2018: Average rating for course: 3.49/6.00; average rating for instructor: 4.11/6.00

Polymer Chemistry Winter 2017 Northwestern University, Department of Chemistry (7 graduate, 5 undergraduate students) • Average rating for course: 5.57/6.00; average rating for instructor: 5.71/6.00

Organic Reaction Mechanisms Fall 2016-2017 Northwestern University, Department of Chemistry • 2017: 29 graduate, 3 undergraduate students; average rating for course: 4.88/6.00; average rating for instructor: 5.25/6.00 • 2016: 14 graduate, 4 undergraduate students; average rating for course: 4.89/6.00; average rating for instructor: 4.83/6.00

Preceptor, Organic Chemistry I Fall 2009 Princeton University, Department of Chemistry (80 students, 3 sections) • Average rating for instructor: 3.98/5.00

Teaching Assistant, Intensive General Chemistry Laboratory Spring 2007–2008 Columbia University, Department of Chemistry (12 students, 2 sections)

Peer-Led Learning Center Fall 2006 Columbia University, Department of Chemistry

MENTORSHIP

Graduate students: Boyeong Kang (2017–present), Christopher Eckdahl (2017–present), David Barsoum (2017–present), Xiaodi Wang (2016–present), Joseph Accardo (2016–present), Eliot Woods (2016–present)

Postdoctoral scholars: Youlong Zhu (2016–2017), Jacob Ishibashi (2017–present)

Undergraduate students: Kim Phan (Augustana College ’19, 2017), Colin Clayton, (Northwestern ’18, 2016–2017), Yan Fang (Northwestern ’19, 2016–present), Xinping He (Tianjin U. ’15, 2014-2015), Dana Schmitt (Princeton ’12, 2011-2012)

INTERNAL SERVICE

Speaker, Graduate Society of Women Engineers at Northwestern 2017 Student award committees: Gelewitz (2017–2018), Ryan (2017), Presidential Fellowship (2017) 2017– Reader for undergraduate honors theses 2017– 2017 (1): Kalli Koukounas Qualifying exam committee member (* = chair) 2017– 2018 (5): Coleton Carter, Austin Evans, Yishu Jiang, Miles Markmann, Eric Miller 2017 (9): Diego Alzate, Louis Redfern, Woojung Ji, Max Klemes, Rachel Snyder, Yuan Liu, David Barsoum, Jennifer Rote, Xi Chen (ChBE) Graduate admissions committee 2016– Julia Kalow: curriculum vitae 5

EXTERNAL SERVICE

Reviewing Panel reviewer, NSF GRFP 2018 External reviewer, DOD NDSEG 2018 Study section early career reviewer, NIH BMBI 2017 Panel reviewer, NSF CHE 2017, 2018 Reviewer (J. Am. Chem. Soc. (7), Nature Chemistry (2), Nature Communications (1), Macromolecules (13), ACS Macro Letters (3), J. Mat. Chem. C (1)) 2014–present

Conference service Discussion leader, Stereochemistry Gordon Research Conference 2018 Session presider, POLY Photochemistry and Polymers, ACS New Orleans 2018 Poster judge, POLY Sci-Mix, ACS DC 2017 Session presider, PMSE Dynamic Chemistry in Polymer Materials, ACS DC 2017 Session presider, RSC Polymer Chemistry Symposium, ACS San Francisco 2017 Session presider, PMSE Young Investigator Symposium, ACS San Francisco 2017 Session presider, ORGN Chemistry of Fullerenes, Carbon Nanotubes, and Graphene, ACS Philadelphia 2016 Discussion leader, Gordon Research Seminar in Polymer Chemistry 2015

Leadership Co-organizer, Chicago Organic Symposium, Northwestern University 2018 Co-organizer, Chicago Organic Symposium, University of Illinois at Chicago 2017 Contributor and team captain, SYNFACTS 2014

Mentorship NSF Future Faculty Workshop for women and underrepresented minorities, University of Delaware 2018 ChemWMN Network 2018-present NSF Future Faculty Workshop for women and underrepresented minorities, Case Western Reserve University, Cleveland, OH 2017

Kalow Group outreach participation Host summer research students for The Graduate School’s Summer Research Opportunity Program aimed at increasing diversity Summer 2017 Lab tours for high school students with NU’s Society of Hispanic Professional Engineers April 2017 High school science fair judges December 2016 National Chemistry Week hands-on demonstration of low-cost sensors (Loyola University) October 2016

INVITED PRESENTATIONS 3M Science and Engineering Faculty Day, Minneapolis, MN, June 2018: “Reactivity-property relationships in dynamic polymer networks.” 4th Functional Polymeric Materials Conference, Nassau, Bahamas, June 2018: “Reactivity-property relationships in photocontrolled polymer networks.” Miami University, Chemistry and Biochemistry Department, Oxford, OH, April 2018: “Reactivity-property relationships in dynamic polymer networks.” Julia Kalow: curriculum vitae 6

255th ACS National Meeting, Photochemistry and Polymers Symposium (POLY), New Orleans, LA, March 2018: “Photocontrol of crosslink exchange kinetics in hydrogels and vitrimers.” Boston Symposium on Organic and Bioorganic Chemistry, Boston, MA, October 2015: “Synthesis and Self- Assembly of Soft Materials for Biosensing.” Rising Stars in Chemistry Symposium, University of Chicago, Chicago, IL, June 2015: “Synthetic strategies for spatial control from the molecular to macro scale.” Polymer Day, MIT, Cambridge, MA, March 2015: “ROMPing in and out: synthesis and self-assembly of conjugated H-shaped polymers.”

CONTRIBUTED PRESENTATIONS Kalow, J. A. “Selective activation by substrate photoexcitation for polymer synthesis.” 254th ACS National Meeting, POLY division (poster), Washington, DC, August 2017. Kalow, J. A. “Photocontrol of viscoelastic hydrogels.” 254th ACS National Meeting, PMSE division (oral presentation), Washington, DC, August 2017. Woods, E. F.; Wang, X.; Accardo, J. V.; Fang, Y.; Clayton, C. Y.; Kalow, J. A. “Substrate photoexcitation by visible light for spatiotemporally controlled polymerization and crosslinking.” Polymers Gordon Research Conference (poster), South Hadley, MA, June 2017. Kalow, J. A.; Swager, T. M. “ROMPing in and out: synthesis and self-assembly of conjugated H-shaped polymers.” 250th ACS National Meeting, POLY division (oral presentation), Boston, MA, August 2015. Kalow, J. A.; Zarzar, L. D.; He, X.; Swager, T. M. “Responsive responsive surfactants for biosensing with dynamic complex emulsions.” 250th ACS National Meeting, ORGN division (oral presentation), Boston, MA, August 2015. Kalow, J. A.; Zarzar, L. D.; He, X.; Swager, T. M. “Design and synthesis of responsive surfactants for dynamic complex emulsions.” Organic Reactions & Processes Gordon Research Conference (poster), Lewiston, ME, July 2015. Kalow, J. A.; Swager, T. M. “ROMPing in and out: synthesis and self-assembly of conjugated H-shaped polymers.” Polymer Chemistry Gordon Research Conference and Symposium (poster), South Hadley, MA, June 2015. Kalow, J. A.; Swager, T. M. “H-shaped conjugated block copolymers: synthesis and self-assembly.” Materials Research Society National Meeting (poster), Boston, MA, December 2014. Kalow, J. A.; Graham, T. J.; Lambert, R. F.; Doyle, A. G. “New methods for asymmetric nucleophilic fluorination and radiofluorination.” National Organic Symposium (poster), Seattle, WA, June 2013. Kalow, J. A.; Doyle, A. G. “Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source.” 244th ACS National Meeting (oral presentation), Philadelphia, PA, August 2012. Kalow, J. A.; Doyle, A. G. “Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source.” ISACS7: Challenges in Organic Chemistry and Chemical Biology (poster), Edinburgh, UK, June 2012. Kalow, J. A.; Doyle. A. G. “Cooperative Catalysis in the Enantioselective Ring Opening of Epoxides and Aziridines by Fluoride Anion.” National Organic Symposium (poster), Princeton, NJ, June 2011. Julia Kalow: curriculum vitae 7

Kalow, J. A.; Doyle, A. G. “Enantioselective Ring Opening with Fluoride Anion Promoted by a Cooperative Dual-Catalyst System.” Pacifichem (poster), Honolulu, HI, December 2010.

PATENT APPLICATIONS

J. A. Kalow, J. V. Accardo. “Photocontrolled dynamic covalent linkers for polymer networks.” Filed 2018, U.S. Provisional Patent Application: 62/673,312.

T. M. Swager, E. D. Blankschtein, L. D. Zarzar, V. Sresht, E. M. Sletten, J. A. Kalow, “Compositions and methods for arranging colloid phases.” Filed 2014, US Provisional Patent: 62/073915.

T. M. Swager, E. D. Blankschtein, L. D. Zarzar, V. Sresht, E. M. Sletten, J. A. Kalow, “Compositions and methods for forming emulsions.” Filed 2014, US Provisional Patent: 62/073896.

AFFILIATIONS

Member, International Institute of Nanotechnology 2016–present Member, Materials Research Society 2014–present Member, American Chemical Society, Division of Organic Chemistry 2011–present