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KETOCONAZOLE Your Dosage Is: Ketoconazole Can Increase Liver Enzymes

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KETOCONAZOLE Your Dosage Is: Ketoconazole Can Increase Liver Enzymes Your dosage is: KETOCONAZOLE Ketoconazole can increase liver enzymes . 200 mg tablet This usually does not give any symptoms. Other names: Nizoral Rarely, hepatitis (an inflammation of the ____tablet(s) (____mg) ____time(s) a day liver) can occur. Signs of this are yellowing WHY is this drug prescribed? of the eyes and skin, dark urine, fever, or nausea and / or vomiting, pale stools, Ketoconazole is an antifungal drug. It is fatigue, and abdominal pain. Call your used to treat fungal infections in the mouth 20 mg / mL oral suspension doctor or pharmacist if these symptoms (like thrush), the esophagus, the genital occur. tract (like a yeast infection) and other areas. ____mL (____mg) ____ time(s) a day The drug may also be used to prevent a Other rare adverse effects that may occur relapse after treatment of the initial infection. Shake well before each use include lowering of white blood cells (cells that fight infections), and lowering of HOW should this drug be taken? Take ketoconazole for the duration of time it platelets (needed to help your blood clot). is prescribed. If you stop it earlier, your Inform your doctor if you notice any Ketoconazole is available in 200 mg tablets infection may come back. If the infection symptoms of fever, chills, bleeding or and a 20 mg/mL oral suspension. worsens or persists, consult your doctor. bruising. The dose of ketoconazole will depend on the What should you do if you FORGET a Your doctor will do regular blood tests to type of infection that is being treated. It is dose? verify your liver and adrenal gland function usually given once daily. as well as your white blood cell and platelet If you miss a dose of ketoconazole, take it count. Ketoconazole should be taken with a meal. as soon as possible. However, if it is time Avoid taking an antacid (Maalox , Tums , for your next dose, do not double the dose, What other PRECAUTIONS should you etc) at the same time, since an acid just carry on with your regular schedule. follow while using this drug? environment in the stomach is necessary for ketoconazole to be well absorbed. If you What ADVERSE EFFECTS can this drug Certain drugs can increase or decrease the need to take antacids, it should be taken at cause? What should you do about them? effect of ketoconazole. Also, ketonazole least 1 hour before or 2 hours after the might influence the effect of other drugs you ketoconazole dose is taken. Adverse effects include nausea, are taking. Inform your doctor and abdominal pain, and itching . Less pharmacist of all prescribed and non- If you are taking anti-ulcer drugs that can common side effects include: headache, prescribed drugs you are taking. As well, decrease the acidity of the stomach dizziness, drowsiness, fever, rash, you should inform them of natural products [ranitidine (Zantac ), famotidine (Pepcid ), diarrhea, or impotence. If your eyes you are taking. If you wish to start a new pantoprazole (Pantoloc ), lansoprazole become sensitive to light , consider drug or natural product, please consult with (Prevacid ), omeprazole (Losec ), wearing tinted or dark glasses. Breast your pharmacist before doing so. rabeprazole (Pariet ), esomeprazole pain or tenderness may occur in men. If (Nexium )], absorption may be improved by these effects occur and are bothersome, taking ketoconazole with a carbonated cola please call your doctor or pharmacist or drink or cranberry juice. discuss them at your next visit. You should NOT take the following (“EXP”) shown on the outside of the drugs if your doctor has prescribed package. ketoconazole : Do not store in your bathroom or kitchen, as Astemizole (Hismanal ) heat and moisture may cause the drug to be less active. Cisapride (Prepulsid ) Dofetilide Eletriptan If you have any questions or concerns KETOCONAZOLE Ergot alkaloids such as about this drug or if you are experiencing dihydroergotamine, ergometrine adverse effects, please discuss them with (ergonovine), ergotamine and your pharmacist, doctor or nurse. methylergometrine (methylergonovine) Levomethadyl Write questions or concerns down to MEDICATION Lovastatin (Mevacor ) ensure they are addressed. Oral Midazolam (Versed ) Nisoldipine The following pharmacist is available to FACT SHEET Pimozide (Orap ) answer questions: Quinidine (Biquin Durules ) Pharmacist: ________________ Terfenadine (Seldane ) Simvastatin (Zocor ) Telephone: ________________ Triazolam (Halcion ) Women of childbearing potential should take ketoconazole ONLY if they are using an effective form of birth control (condom, birth control pill). Ketoconazole should not be used in pregnant women. Also, breastfeeding is NOT recommended while you are taking this drug. Please discuss this with your doctor or pharmacist if this is a concern. How should this drug be STORED? Ketoconazole should be stored at room Reference: Product monograph Nizoral (ketoconazole). temperature in a cool (15-30 °C) dry place, North York, On, Canada: Janssen-Ortho Inc, 1998. Prepared by the Ontario HIV Pharmacy Professional protected from light and well out of the Specialty Group, 2003. Reviewed 2009. reach of children. Ensure that the drug has Additional medication fact sheets and updates may be found not expired by checking the expiry date at: www.hivclinic.ca .
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