Review A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions Liani Coronado 1, Carmen L. Perera 1, Liliam Rios 2, María T. Frías 1 and Lester J. Pérez 3,*,† 1 National Centre for Animal and Plant Health (CENSA), OIE Collaborating Centre for Disaster Risk Reduction in Animal Health, San José de las Lajas 32700, Cuba;
[email protected] (L.C.);
[email protected] (C.L.P.);
[email protected] (M.T.F.) 2 Reiman Cancer Research Laboratory, Faculty of Medicine, University of New Brunswick, Saint John, NB E2L 4L5, Canada;
[email protected] 3 Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Illinois at Urbana–Champaign, Champaign, IL 61802, USA * Correspondence:
[email protected] † New Affiliation: Virus Discovery Group, Abbott Diagnostics, Abbott Park, IL 60064, USA. Abstract: Classical swine fever (CSF) is, without any doubt, one of the most devasting viral infec- tious diseases affecting the members of Suidae family, which causes a severe impact on the global economy. The reemergence of CSF virus (CSFV) in several countries in America, Asia, and sporadic outbreaks in Europe, sheds light about the serious concern that a potential global reemergence of this disease represents. The negative aspects related with the application of mass stamping out policies, including elevated costs and ethical issues, point out vaccination as the main control measure against future outbreaks. Hence, it is imperative for the scientific community to continue with the active Citation: Coronado, L.; Perera, C.L.; investigations for more effective vaccines against CSFV.