11. Protocols for Experiments
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On Becoming a Pragmatic Researcher: the Importance of Combining Quantitative and Qualitative Research Methodologies
DOCUMENT RESUME ED 482 462 TM 035 389 AUTHOR Onwuegbuzie, Anthony J.; Leech, Nancy L. TITLE On Becoming a Pragmatic Researcher: The Importance of Combining Quantitative and Qualitative Research Methodologies. PUB DATE 2003-11-00 NOTE 25p.; Paper presented at the Annual Meeting of the Mid-South Educational Research Association (Biloxi, MS, November 5-7, 2003). PUB TYPE Reports Descriptive (141) Speeches/Meeting Papers (150) EDRS PRICE EDRS Price MF01/PCO2 Plus Postage. DESCRIPTORS *Pragmatics; *Qualitative Research; *Research Methodology; *Researchers ABSTRACT The last 100 years have witnessed a fervent debate in the United States about quantitative and qualitative research paradigms. Unfortunately, this has led to a great divide between quantitative and qualitative researchers, who often view themselves in competition with each other. Clearly, this polarization has promoted purists, i.e., researchers who restrict themselves exclusively to either quantitative or qualitative research methods. Mono-method research is the biggest threat to the advancement of the social sciences. As long as researchers stay polarized in research they cannot expect stakeholders who rely on their research findings to take their work seriously. The purpose of this paper is to explore how the debate between quantitative and qualitative is divisive, and thus counterproductive for advancing the social and behavioral science field. This paper advocates that all graduate students learn to use and appreciate both quantitative and qualitative research. In so doing, students will develop into what is termed "pragmatic researchers." (Contains 41 references.) (Author/SLD) Reproductions supplied by EDRS are the best that can be made from the original document. On Becoming a Pragmatic Researcher 1 Running head: ON BECOMING A PRAGMATIC RESEARCHER U.S. -
Survey Experiments
IU Workshop in Methods – 2019 Survey Experiments Testing Causality in Diverse Samples Trenton D. Mize Department of Sociology & Advanced Methodologies (AMAP) Purdue University Survey Experiments Page 1 Survey Experiments Page 2 Contents INTRODUCTION ............................................................................................................................................................................ 8 Overview .............................................................................................................................................................................. 8 What is a survey experiment? .................................................................................................................................... 9 What is an experiment?.............................................................................................................................................. 10 Independent and dependent variables ................................................................................................................. 11 Experimental Conditions ............................................................................................................................................. 12 WHY CONDUCT A SURVEY EXPERIMENT? ........................................................................................................................... 13 Internal, external, and construct validity .......................................................................................................... -
Repko Research Process (Study Guide)
Beginning the Interdisciplinary Research Process Repko (6‐7) StudyGuide Interdisciplinary Research is • A decision‐making process – a deliberate choice • A decision‐making process – a movement, a motion • Heuristic – tool for finding out – process of searching rather than an emphasis on finding • Iterative – procedurally repetitive – messy, not linear – fluid • Reflexive – self‐conscious or aware of disciplinary or personal bias – what influences your work (auto) Integrated Model (p.141) Problem – Insights – Integration – Understanding fine the problem The Steps include: A. Drawing on disciplinary insights 1. Define the problem 2. Justify using an id approach 3. Identify relevant disciplines 4. Conduct a literature search 5. Develop adequacy in each relevant discipline 6. Analyze the problem and evaluate each insight into it B. Integrate insights to produce id understanding 7. Identify conflicts between insights and their sources 8. Create or discover common ground 9. Integrate insights 10. Produce an id understanding of the problem (and test it) Cautions and concerns (1) Fluid steps (2) Feedback loops – not a ladder Beginning the Interdisciplinary Research Process Repko (6‐7) StudyGuide (3) Don’t skip steps – be patient (4) Integrate as you go STEP ONE: Define the Problem • Researchable in an ID sense? • What is the SCOPE (parameters; disclaimers; what to include, exclude; what’s your focus – the causes, prevention, treatment, effects, etc. • Is it open‐ended • Too complex for one discipline to solve? Writing CHECK – Craft a well‐composed -
Research Questions in Design-Based Research Arthur Bakker
Research Questions in Design-Based Research Arthur Bakker Freudenthal Institute Utrecht University [email protected] August 25, 2014 Design-based research (DBR) is a relatively new method in the learning sciences (Anderson & Shattuck, 2012; Brown, 1992; also see special issues in Educational Researcher, 2003; Educational Psychologist, 2004; Journal of the Learning Sciences, 2004). For older and more established methods such as randomized controlled trials (RCTs), the argumentative logic has already been worked out more clearly (Cobb et al., in press). Several predominantly qualitative approaches such as ethnography, case studies and action research have been around so long that they are discussed in most research methods books (Creswell, 2007; Denscombe, 2007), but DBR has not yet reached this stage. Despite its potential and importance for the improvement of education and educational research (Plomp & Nieveen, 2007; Van den Akker et al., 2006), there is thus still some way to go. In this document I focus on the topic of research questions. Many design-based researchers struggle with formulating good research questions, and in many cases the debate on formulations continues until the end of a project. To some extent this inherent in qualitative research approaches, but in DBR the situation seems more poignant. I address the issue of what counts as a good research question, summarize some of the discussion points and propose an argumentative structure that seems to work for the type of DBR that our students in mathematics and science education do. I do not rehearse the main characteristics of DBR (see Bakker & van Eerde, 2014; Cobb et al., 2003). -
Developing a Protocol
FACILITATOR/MENTOR GUIDE Developing a Protocol Created: 2013 Developing a Protocol. Atlanta, GA: Centers for Disease Control and Prevention (CDC), 2013. DEVELOPING A PROTOCOL Table of Contents LEARNING OBJECTIVES ................................................................................................... 3 ESTIMATED COMPLETION TIME ........................................................................................ 3 TARGET AUDIENCE ......................................................................................................... 3 PRE-WORK AND PREREQUISITES ..................................................................................... 3 MATERIALS .................................................................................................................... 4 OPTIONS FOR FACILITATING THIS TRAINING ....................................................................... 4 ICON GLOSSARY ............................................................................................................ 5 ACKNOWLEDGEMENTS .................................................................................................... 5 FACILITATOR RESPONSIBILITIES ...................................................................................... 7 SECTIONS 1 & 2: INTRODUCTION AND OVERVIEW .............................................................. 8 SECTION 3: WRITING A PROPOSAL OR CONCEPT PAPER ..................................................... 9 SECTION 4: WRITING A DRAFT OF THE PROTOCOL ........................................................... -
How to Write a Systematic Review Article and Meta-Analysis Lenka Čablová, Richard Pates, Michal Miovský and Jonathan Noel
CHAPTER 9 How to Write a Systematic Review Article and Meta-Analysis Lenka Čablová, Richard Pates, Michal Miovský and Jonathan Noel Introduction In science, a review article refers to work that provides a comprehensive and systematic summary of results available in a given field while making it pos- sible to see the topic under consideration from a new perspective. Drawing on recent studies by other researchers, the authors of a review article make a critical analysis and summarize, appraise, and classify available data to offer a synthesis of the latest research in a specific subject area, ultimately arriving at new cumulative conclusions. According to Baumeister and Leary (1997), the goal of such synthesis may include (a) theory development, (b) theory evalu- ation, (c) a survey of the state of knowledge on a particular topic, (d) problem identification, and (e) provision of a historical account of the development of theory and research on a particular topic. A review can also be useful in science and practical life for many other reasons, such as in policy making (Bero & Jadad, 1997). Review articles have become necessary to advance addiction sci- ence, but providing a systematic summary of existing evidence while coming up with new ideas and pointing out the unique contribution of the work may pose the greatest challenge for inexperienced authors. How to cite this book chapter: Čablová, L, Pates, R, Miovský, M and Noel, J. 2017. How to Write a Systematic Review Article and Meta-Analysis. In: Babor, T F, Stenius, K, Pates, R, Miovský, M, O’Reilly, J and Candon, P. -
Sample Size for Clinical Trials Martin Bland Prof
British Standards Institution Study Day Sample size for clinical trials Martin Bland Prof. of Health Statistics University of York http://martinbland.co.uk Outcome variables for trials An outcome variable is one which we hope to change, predict or estimate in a trial. Examples: • Systolic blood pressure in a hypertension trial • Caesarean section rate in an obstetric trial • Survival time in a cancer trial How many outcome variables should I have? If we have many outcome variables: • all possibilities would be covered, • we would be less likely to miss something, • the risk of false positives, finding an apparent effect when there is none in reality, would be increased. If we have few outcome variables: • the trial would be easier and quicker to check and analyse, • the trial would be cheaper, • the trial would be easier for research subjects, • we would avoid multiple testing and the high risk of a false positive result. We get round the problem of multiple testing by having one outcome variable on which the main conclusion stands or falls, the primary outcome variable. If we do not find an effect for this variable, the study has a negative result. Usually we have several secondary outcome variables, to answer secondary questions. A significant difference for one of these would generate further questions to investigate rather than provide clear evidence for a treatment effect. The primary outcome variable must relate to the main aim of the study. Choose one and stick to it. How large a sample should I take? A significance test for comparing two means is more likely to detect a large difference between two populations than a small one. -
Phase 3 Clinical Study Protocol
ModernaTX, Inc. 20 Aug 2020 Protocol mRNA-1273-P301, Amendment 3 mRNA-1273 CLINICAL STUDY PROTOCOL Protocol Title: A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older Protocol Number: mRNA-1273-P301 Sponsor Name: ModernaTX, Inc. Legal Registered Address: 200 Technology Square Cambridge, MA 02139 Sponsor Contact and Tal Zaks, MD, PhD, Chief Medical Officer Medical Monitor: ModernaTX, Inc. 200 Technology Square, Cambridge, MA 02139 Telephone: 1-617-209-5906 e-mail: [email protected] Regulatory Agency Identifier Number(s): IND: 19745 Amendment Number: 3 Date of Amendment 3: 20 Aug 2020 Date of Amendment 2: 31 Jul 2020 Date of Amendment 1: 26 Jun 2020 Date of Original Protocol: 15 Jun 2020 CONFIDENTIAL All financial and nonfinancial support for this study will be provided by ModernaTX, Inc. The concepts and information contained in this document or generated during the study are considered proprietary and may not be disclosed in whole or in part without the expressed written consent of ModernaTX, Inc. The study will be conducted according to the International Council for Harmonisation (ICH) Technical Requirements for Registration of Pharmaceuticals for Human Use, E6(R2) Good Clinical Practice (GCP) Guidance. Confidential Page 1 ModernaTX, Inc. 20 Aug 2020 Protocol mRNA-1273-P301, Amendment 3 mRNA-1273 PROTOCOL APPROVAL – SPONSOR SIGNATORY Study Title: A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older Protocol Number: mRNA-1273-P301 Protocol Version Date: 20 Aug 2020 Protocol accepted and approved by: See esignature and date signed on last page of document. -
The Research Project “CINTERA” and the Study of Marine Eutrophication
Sustainability 2015, 7, 9118-9139; doi:10.3390/su7079118 OPEN ACCESS sustainability ISSN 2071-1050 www.mdpi.com/journal/sustainability Article Interdisciplinarity as an Emergent Property: The Research Project “CINTERA” and the Study of Marine Eutrophication Jennifer Bailey 1,*, Murat Van Ardelan 2, Klaudia L. Hernández 3, Humberto E. González 4,5,6, José Luis Iriarte 4,5,7, Lasse Mork Olsen 1, Hugo Salgado 8,9 and Rachel Tiller 10 1 Department of Sociology and Political Science, Norwegian University of Science and Technology, 7491 Trondheim, Norway; E-Mail: [email protected] 2 Department of Chemistry, Norwegian University of Science and Technology, 7491 Trondheim, Norway; E-Mail: [email protected] 3 Centro de Investigaciones Marinas Quintay CIMARQ, Facultad de Ecologia y Recursos Naturales, Universidad Andres Bello, 2340000 Valparaiso, Chile; E-Mail: [email protected] 4 Programa de Financiamiento Basal, COPAS Sur Austral, 4030000 Concepción, Chile; E-Mails: [email protected] (H.E.G.); [email protected] (J.L.I.) 5 Centro de Investigaciones di Ecosistemas de la Patagonia (CIEP), Coyhaique 5950000, Chile 6 Instituto de Ciencias Marinas y Limnológicas, Universidad Austral de Chile, 5090000 Valdivia, Chile 7 Instituto de Acuicultura, Universidad Austral de Chile and Centro de Investigación en Ecosistemas de la Patagonia-CIEP, 5480000 Puerto Montt, Chile 8 Facultad de Economía y Negocios, Research Nucleus on Environmental and Resource Economics (NENRE), Universidad de Talca, 2 Norte 685 Talca, Chile; E-Mail: [email protected] 9 Interdisciplinary Center in Aquaculture Research (INCAR), Universidad de Talca; 2 Norte 685 Talca, Chile 10 SINTEF, Aquaculture and Fisheries, P.O. -
Chapter 13*: EPIDEMIOLOGY
Monitoring Bathing Waters - A Practical Guide to the Design and Implementation of Assessments and Monitoring Programmes Edited by Jamie Bartram and Gareth Rees © 2000 WHO. ISBN 0-419-24390-1 Chapter 13*: EPIDEMIOLOGY * This chapter was prepared by D. Kay and A. Dufour Epidemiological data are frequently used to provide a basis for public health decisions and as an aid to the regulatory process. This is certainly true when developing safeguards for recreational waters where hazardous substances or pathogens discharged to coastal and inland waters may pose a serious risk of illness to individuals who use the waters. Epidemiological studies of human populations not only provide evidence that swimming-associated illness is related to environmental exposure, but also can establish an exposure-response gradient which is essential for developing risk- based regulations. Epidemiology has played a significant role in providing information that characterises risks associated with exposure to faeces contaminated recreational waters. The use of epidemiological studies to define risk associated with swimming in contaminated waters has been criticised because the approach used to collect the data is not experimental in nature. This perception is unlikely to change, given the highly variable environments where recreational exposures take place. Although the variables may be difficult to control, it is possible to carry out credible studies by following certain standard practices that are given below. This Chapter discusses the place of epidemiological investigations in providing information to support recreational water management and the scientific basis of "health-based" regulation. 13.1 Methods employed in recreational water studies Epidemiology is the scientific study of disease patterns in time and space. -
STANDARDS and GUIDELINES for STATISTICAL SURVEYS September 2006
OFFICE OF MANAGEMENT AND BUDGET STANDARDS AND GUIDELINES FOR STATISTICAL SURVEYS September 2006 Table of Contents LIST OF STANDARDS FOR STATISTICAL SURVEYS ....................................................... i INTRODUCTION......................................................................................................................... 1 SECTION 1 DEVELOPMENT OF CONCEPTS, METHODS, AND DESIGN .................. 5 Section 1.1 Survey Planning..................................................................................................... 5 Section 1.2 Survey Design........................................................................................................ 7 Section 1.3 Survey Response Rates.......................................................................................... 8 Section 1.4 Pretesting Survey Systems..................................................................................... 9 SECTION 2 COLLECTION OF DATA................................................................................... 9 Section 2.1 Developing Sampling Frames................................................................................ 9 Section 2.2 Required Notifications to Potential Survey Respondents.................................... 10 Section 2.3 Data Collection Methodology.............................................................................. 11 SECTION 3 PROCESSING AND EDITING OF DATA...................................................... 13 Section 3.1 Data Editing ........................................................................................................ -
Research Questions and Hypotheses
07-Creswell (RD)-45593:07-Creswell (RD)-45593.qxd 6/20/2008 4:37 PM Page 129 CHAPTER SEVEN Research Questions and Hypotheses nvestigators place signposts to carry the reader through a plan for a study. The first signpost is the purpose statement, which establishes the Icentral direction for the study. From the broad, general purpose state- ment, the researcher narrows the focus to specific questions to be answered or predictions based on hypotheses to be tested. This chapter begins by advancing several principles in designing and scripts for writing qualitative research questions; quantitative research questions, objectives, and hypotheses; and mixed methods research questions. QUALITATIVE RESEARCH QUESTIONS In a qualitative study, inquirers state research questions, not objectives (i.e., specific goals for the research) or hypotheses (i.e., predictions that involve variables and statistical tests). These research questions assume two forms: a central question and associated subquestions. The central question is a broad question that asks for an exploration of the central phenomenon or concept in a study. The inquirer poses this question, consistent with the emerging methodology of qualitative research, as a general issue so as to not limit the inquiry. To arrive at this question, ask, “What is the broadest question that I can ask in the study?” Beginning researchers trained in quantitative research might struggle with this approach because they are accustomed to the reverse approach: iden- tifying specific, narrow questions or hypotheses based on a few variables. In qualitative research, the intent is to explore the complex set of factors surrounding the central phenomenon and present the varied perspectives or meanings that participants hold.