The most trusted name in .

In Hebrew, Tikun Olam means “Repair the World.” We embrace this as our mission and are dedicated to improving the lives of our patients by providing high-quality cannabis that is consistently safe and effective. Backed by over a decade of research, our strains are expertly cultivated, medically tested, and patient approved. History & Heritage Commitment to Research In 1964, Dr. Raphael Mechoulam discovered and isolated the Research and development are integral to fulfilling our THC at the Hebrew University of Jerusalem. vision. Building on the discoveries and legacy of Dr. Raphael His findings launched decades of scientific research into Mechoulam, we sustain partnerships and collaborative the therapeutic uses of the cannabis plant. During this time, relations with physicians, scientists, and leading medical Mechoulam mentored our founder, Tzachi Cohen, who was institutions across the world. We continually conduct inspired to open a non-profit organization with a mission laboratory studies, retrospective analyses, and clinical trials to “Repair the World” by providing patients with safe to examine the effects our strains have in the treatment and and consistent cannabis medicine. In 2005, Tikun Olam management of specific symptoms and diseases. Our clinical was born and in 2007, we made history as the world’s first successes have encouraged us to devote more resources to company granted a government-issued license to supply further improve the safety and efficacy of our products, as medical cannabis. well as our understanding of the therapeutic properties of the cannabis plant. Through our ongoing commitment to With ’s blessing, we began partnering with hospitals, research, we’ve earned our reputation as the most trusted nursing homes, and co-ops to distribute our medical grade name in cannabis. cannabis, working with certified nurses to ensure our patients received personalized treatment plans. Through attentive patient care, we amassed what now forms one Global Reach of the world’s largest cannabis treatment databases - with Tikun Olam is proud to be a global leader in medical more than 20,000 patient records noting symptoms, strain cannabis, dedicated to improving the overall wellness and used, dosage, and associated levels of relief. We’ve used this quality of life of our patients worldwide. Through trusted data to develop and genetically optimize our portfolio of partnerships, our medicine now reaches tens of thousands of proprietary cannabis stains, which have now been clinically patients in Australia, Canada, Germany, South Korea, Greece, proven to provide symptomatic relief for a wide variety of the UK, the US, and Israel. Our vision to “Repair the World” conditions, including Crohn’s Disease, Parkinson’s Disease, has become a reality as we continue our global expansion. autism, cancer, IBD, and more.

The Tikun Advantage • Award-winning proprietary Israeli strains that have been genetically optimized to maximize symptomatic relief

• More than ten years of clinical trials and laboratory studies successfully treating ailments like cancer pain, autism, and epilepsy

• World’s only successful Phase II double-blind clinical trial on cannabis for Crohn’s Disease

• High-CBD strain, Avidekel, was named the first “highless marijuana” by Reuters

• One of the world’s largest treatment databases, with over 20,000 patients treated with Tikun cannabis At the cutting edge of cannabis research.

Tikun Olam is a proud pioneer and global leader in cannabis research. Through clinical studies and patient data collection, we are continually examining the effects our strains and products have in the treatment and management of specific symptoms and diseases. Clinical Studies Rooted in Israel’s regulatory environment, Tikun Olam Palliative Cancer Care has conducted cannabis studies and collected patient • This study found that cannabis as a palliative treatment data since 2007. for cancer patients is a well-tolerated, effective, and safe We’ve seen overwhelmingly positive results in cannabis’ option to help patients cope with cancer-related symptoms ability to improve our patients’ quality of life, which has • 95.9% of patients reported an improvement in their motivated our ongoing commitment to research. condition using Midnight, Avidekel, and other THC-rich Below is a select outline of our published studies, as well Tikun Olam strains as internal analyses of our treatment database of over • The most improved symptoms were nausea and 20,000 cannabis patients. vomiting (91%), sleep disorders (87.5%), restlessness Crohn’s Disease (87.5%), anxiety and depression (84.2%), pruritus (82.1%) and headaches (81.4%) • World’s first and only successful Phase II double-blind study using cannabis to treat Crohn’s • 35.1% of patients decreased their drug consumption, including analgesics, sedatives, corticosteroids, and • Using our Erez strain, 45% of patients achieved full opioids remission, based on the Crohn’s Disease Activity Index Symptom Relief • Patients reported significantly less pain, improved appetite and quality of life • In a study of Tikun Olam patients using our strains to treat various ailments, 94% reported an improvement in Parkinson’s Disease their condition

• 82.2% of patients reported that cannabis improved • Most patients experienced pain reduction and many their overall symptoms, including reduction in tremors, reported improved sleep, mood, and appetite muscle stiffness, and pain; improvement in mood and sleep quality • 62% of patients reduced their medication consumption

Palliative Geriatric Care Pain & Inflammation • This study found that the therapeutic use of cannabis is • Our high-CBD strain, Avidekel, exhibited superior a safe and efficacious treatment option for the elderly anti-inflammatory effectiveness to Tramadol (an opioid analgesic) and aspirin (a non-steroid anti-inflammatory) • Using Midnight, Avidekel, and other THC-rich Tikun Olam strains, 95.9% of patients reported an improvement Autism in their condition • Using Avidekel oil, 90.2% of children with ASD reported • Patients reported pain relief, mood improvement, and improvement in their symptoms, including reduction in increase in appetite and sleeping hours rage attacks, restlessness, depression, anxiety, seizures, and digestion problems • 35.1% of patients reduced their number of drugs taken or the dosage, including 18.1% who stopped using opioids • 34.3% of patients decreased medication consumption, or reduced their dose including antipsychotics, antiepileptics, antidepressants, hypnotics, and sedatives; 20% of patients stopped taking Tourette’s Syndrome antipsychotics altogether

• 83% of patients reported improvement in tic quantity, intensity, and premonitory urge Studies in Progress Complex Motor Disorders Tikun Olam’s team of scientists is continually conducting • Using our Avidekel cannabis oil, most participants patient research. We’re currently studying the effects of reported significant improvement in spasticity and cannabis on Colitis, IBD, fibromyalgia, immune response, dystonia, sleep difficulties, pain severity, and quality and more. To stay updated on our research and subscribe of life to our email list, visit trytikun.com. Award-Winning Heirloom Strains

MEDICAL GRADE STRAINS

KEY Midnight Alaska Avidekel Or Erez Eran Almog

Sativa Sativa Indica Indica Indica Indica TYPE 1:1 THC 15:1 CBD:THC THC THC THC

WHEN

Balanced & Uplifiting & Restorative & Relaxing & Serene & Restful & EFFECTS Focused Energizing Anti-Inflammatory Tranquil Calming Soothing

TOP Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha Pinene, Limonene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, TERPENES Linalool Beta-Pinene Limonene Beta-Pinene, Beta-Pinene Limonene Crohn’s/Colitis, Autism, PTSD, Cancer, Crohn’s/Colitis, Insomnia, Appetite, Insomnia, PTSD, Insomnia, PTSD, MEDICAL Chronic Pain, MS, Crohn’s/Colitis, Cancer, ALS, Muscle Fibromyalgia, Depression, Anxiety, Epilepsy, Cancer, ALS, Muscle Spasms, Nausea, Appetite, MS Migraines, Epilepsy, Spasms, Chronic Pain RESEARCH Neurological Ailments Fibromyalgia Muscle Spasms Chronic Pain

MOST COMMON TERPENES

Alpha-Humulene Guaiol Alpha & Beta Pinene Ocimene Beta- Myrcene Beta- Caryophyllene Limonene Linalool

Aroma: Hoppy Aroma: Woodsy Aroma: Pine Aroma: Fruity Aroma: Earthy Aroma: Spicy Aroma: Citrus Aroma: Floral

Effects: appetite Effects:antibacterial, anti- Effects:memory retention, Effects: decongestant, anti- Effects: relaxation, sedation, Effects: pain relief, anti- Effects: elevated mood, Effects: anti-anxiety, suppressant, pain relief, inflammatory, anti-allergen bronchodilator, anti- inflammatory, antibacterial, pain relief, anti-inflammatory,anxiety, antidepressant, stress relief, antibacterial, sedation, anticonvulsant, antibacterial, anti- inflammatory, antiseptic, antiviral antioxidant antioxidant, anti immunostimulant anti-inflammatory, pain relief inflammatory, anti-tumor antioxidant inflammatory

CALIFORNIA PRODUCT LINE

Vaporizer Topical Tincture • High-purity distillate • All natural ingredients • All natural & high-potency • Full strain flavor & • Terpene & vitamin enriched • Strain-specific terpenes,

terpene profile • 2oz cream, 250mg of CO2 extracted • .5g and 1g cartridges • 1oz oil, 600mg of cannabinoids KEY Midnight Alaska Avidekel Or Erez Eran Almog

Sativa Sativa Indica Indica Indica Indica TYPE 1:1 THC 15:1 CBD:THC THC THC THC

WHEN

Balanced & Uplifiting & Restorative & Relaxing & Serene & Restful & EFFECTS Focused Energizing Anti-Inflammatory Tranquil Calming Soothing

TOP Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha Pinene, Limonene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Alpha-Pinene, Beta-Myrcene, Linalool Beta-Pinene Limonene Beta-Pinene, Beta-Pinene Limonene TERPENES Avidekel High Times Dope Cup Canadian Cannabis Awards Crohn’s/Colitis, Autism, PTSD, Cancer, Insomnia, PTSD, Best CBD Vape Cartridge (2019) Top High CBD Flower (2017) Chronic Pain, MS, Crohn’s/Colitis, Insomnia, Appetite, Insomnia, PTSD, MEDICAL Depression, Anxiety, Crohn’s/Colitis, Cancer, ALS, Muscle Best Sublingual (2019) Top High CBD Oil (2017) Fibromyalgia, Migraines, Epilepsy, Epilepsy, Cancer, ALS, Muscle Spasms, Nausea, Appetite, MS Muscle Spasms Spasms, Chronic Pain Chronic Pain Top High CDB Strain (2015, 2016) RESEARCH Neurological Ailments Fibromyalgia Seattle Hempfest Most Potent CBD Flower (2018) Rolling Stone’s 5 Best Strains of 2017

Midnight Eran Almog Erez High Times Dope Cup Canadian Cannabis Awards Canadian Cannabis Awards Best Topical (2019) Top High THC Flower (2017) Top Indica Strain (2014)

Canadian Cannabis Awards Top Hybrid Flower (2017) Top Hybrid Strain (2014, 2016) Top High CBD Strain (2014)