Drug-Free Workplace Policy Statement Employee Acknowledgement Form
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SENATE BILL No. 52
As Amended by Senate Committee Session of 2017 SENATE BILL No. 52 By Committee on Public Health and Welfare 1-20 1 AN ACT concerning the uniform controlled substances act; relating to 2 substances included in schedules I, II and V; amending K.S.A. 2016 3 Supp. 65-4105, 65-4107 and 65-4113 and repealing the existing 4 sections. 5 6 Be it enacted by the Legislature of the State of Kansas: 7 Section 1. K.S.A. 2016 Supp. 65-4105 is hereby amended to read as 8 follows: 65-4105. (a) The controlled substances listed in this section are 9 included in schedule I and the number set forth opposite each drug or 10 substance is the DEA controlled substances code which has been assigned 11 to it. 12 (b) Any of the following opiates, including their isomers, esters, 13 ethers, salts, and salts of isomers, esters and ethers, unless specifically 14 excepted, whenever the existence of these isomers, esters, ethers and salts 15 is possible within the specific chemical designation: 16 (1) Acetyl fentanyl (N-(1-phenethylpiperidin-4-yl)- 17 N-phenylacetamide)......................................................................9821 18 (2) Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4- 19 piperidinyl]-N-phenylacetamide)..................................................9815 20 (3) Acetylmethadol.............................................................................9601 21 (4) AH-7921 (3.4-dichloro-N-[(1- 22 dimethylaminocyclohexylmethyl]benzamide)...............................9551 23 (4)(5) Allylprodine...........................................................................9602 -
Demonstration and Affinity Labeling of a Stereoselective Binding Site for A
Proc. Nati. Acad. Sci. USA Vol. 82, pp. 940-944, February 1985 Neurobiology Demonstration and affinity labeling of a stereoselective binding site for a benzomorphan opiate on acetylcholine receptor-rich membranes from Torpedo electroplaque (cholinergic receptor/ion channel/photoaffinity labeling/N-aliyl-N-normetazocine/phencyclidine) ROBERT E. OSWALD, NANCY N. PENNOW, AND JAMES T. MCLAUGHLIN Department of Pharmacology, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 Communicated by R. H. Wasserman, October 3, 1984 ABSTRACT The interaction of an optically pure benzo- Benzomorphan opiates have been shown to inhibit the morphan opiate, (-)-N-allyl-N-normetazocine [(-)-ANMC], binding of [3H]PCP to central nervous system synaptic mem- with the nicotinic acetylcholine receptor from Torpedo electro- branes (15, 16) and to modify the activity of serum cholines plaque was studied by using radioligand binding and affinity terase (17). Some opiate derivatives, in particular the benzo- labeling. The binding was complex with at least two specific morphans, can inhibit the binding of [3H]perhydrohistrioni- components having equilibrium dissociation constants of 0.3 cotoxin and [3H]PCP to the Torpedo AcChoR (18, 19). In the jiM and 2 jiM. The affinity of the higher affinity component present studies, a radioactive optically pure benzomorphan, was decreased by carbamoylcholine but not by a-bungaro- (-)-[3H]N-allyl-N-normetazocine {(-)-[3H]ANMC}, was toxin. The effect of carbamoylcholine was not blocked by a- used to measure reversible binding to and affinity labeling of bungarotoxin. In comparison, the affinity of [3Hlphencycli- the Torpedo electroplaque AcChoR. Specific binding was dine, a well-characterized ligand for a high-affinity site for shown to be complex with at least one component having noncompetitive blockers on the acetylcholine receptor, is in- lower affinity in the presence rather than the absence of cho- creased by carbamoylcholine and the increase is blocked by a- linergic effectors. -
Drugs of Abuseon September Archived 13-10048 No
U.S. DEPARTMENT OF JUSTICE DRUG ENFORCEMENT ADMINISTRATION WWW.DEA.GOV 9, 2014 on September archived 13-10048 No. v. Stewart, in U.S. cited Drugs of2011 Abuse EDITION A DEA RESOURCE GUIDE V. Narcotics WHAT ARE NARCOTICS? Also known as “opioids,” the term "narcotic" comes from the Greek word for “stupor” and originally referred to a variety of substances that dulled the senses and relieved pain. Though some people still refer to all drugs as “narcot- ics,” today “narcotic” refers to opium, opium derivatives, and their semi-synthetic substitutes. A more current term for these drugs, with less uncertainty regarding its meaning, is “opioid.” Examples include the illicit drug heroin and pharmaceutical drugs like OxyContin®, Vicodin®, codeine, morphine, methadone and fentanyl. WHAT IS THEIR ORIGIN? The poppy papaver somniferum is the source for all natural opioids, whereas synthetic opioids are made entirely in a lab and include meperidine, fentanyl, and methadone. Semi-synthetic opioids are synthesized from naturally occurring opium products, such as morphine and codeine, and include heroin, oxycodone, hydrocodone, and hydromorphone. Teens can obtain narcotics from friends, family members, medicine cabinets, pharmacies, nursing 2014 homes, hospitals, hospices, doctors, and the Internet. 9, on September archived 13-10048 No. v. Stewart, in U.S. cited What are common street names? Street names for various narcotics/opioids include: ➔ Hillbilly Heroin, Lean or Purple Drank, OC, Ox, Oxy, Oxycotton, Sippin Syrup What are their forms? Narcotics/opioids come in various forms including: ➔ T ablets, capsules, skin patches, powder, chunks in varying colors (from white to shades of brown and black), liquid form for oral use and injection, syrups, suppositories, lollipops How are they abused? ➔ Narcotics/opioids can be swallowed, smoked, sniffed, or injected. -
Controlled Drug Schedules, Violations & Penalties
CONTROLLED DRUG SCHEDULES, VIOLATIONS & PENALTIES A REFERENCE FOR THE LAW ENFORCEMENT COMMUNITY April 2015 Prepared by the DEPARTMENT OF CONSUMER PROTECTION Drug Control Division TABLE OF CONTENTS SECTION I CONTROLLED DRUG SCHEDULES & VIOLATIONS An alphabetical listing of controlled drugs by their brand, generic and/or street name that includes each drug’s schedule and the violation(s) from the Connecticut General Statutes (CGS) that are associated with each drug’s sale and/or possession. SECTION II CONTROLLED DRUG VIOLATIONS & PENALTIES A numerical listing of controlled drug violations by their section number in the Connecticut General Statutes (CGS) and the penalty(ies) associated with each violation. SECTION III SUMMARY OF FEDERAL METHAMPHETAMINE STATUTES 2 S E C T I O N I CONTROLLED DRUG SCHEDULES & VIOLATIONS The ‘Schedules of Controlled Substances’ may be found in Sections 21a-243-7 through 21a-243-11, inclusive, of the Regulations of Connecticut State Agencies. www.ct.gov/dcp/lib/dcp/dcp_regulations/21a-243_designation_of_controlled_drugs.pdf 3 Drug State CS Drug Type AKA Sale or Quantity Person Drug- CGS Schedule Possession? Dependent or Not Violation APAP = Acetaminophen APAP = Acetaminophen Drug-Dependent ? ASA = Aspirin ASA = Aspirin “2C-C” Designer Drug - Stimulant “Bath Salts” Federal CS Schedule 1 “2C-D” Designer Drug - Stimulant “Bath Salts” Federal CS Schedule 1 “2C-E” Designer Drug - Stimulant “Bath Salts” Federal CS Schedule 1 “2C-H” Designer Drug - Stimulant “Bath Salts” Federal CS Schedule 1 “2C-I” Designer Drug - Stimulant -
Outline for Controlled Substances Program
Environmental Health and Safety Controlled Substances Program Date of Issuance: Review Date: 10/1/2019 (no changes) 10/01/2018 Revision Number: Initial Prepared by: EH&S Table of Contents HEADINGS Introduction Applicability Responsibilities Registration Requirements Authorized Use Ordering/Purchasing Administering and Dispensing Inventory Procedures (Continuing Records) Security Disposal FORMS: Registering or renewing a DEA or state license (CMU) Controlled Substances Authorized users list (CMU) Employee questionnaire for those with access to controlled substances (CMU) Record of Form 222 use (Order form) (CMU) Records of Controlled Substance Purchases (CMU) Record of Controlled Substance Administering and dispensing (CMU) Controlled Substance Physical Inventory (CMU) DEA Registration of Persons doing research or analysis (Form 225) DEA Registration of Dispensers (Form 224) DEA Registration Instructional (Form 224 and 226 to renew) DEA Report of loss or theft (Form 106) DEA Report of drugs surrendered (From 41) DEA SCHEDULES: Schedule I Schedule II Schedule III Schedule IV Schedule V INTRODUCTION State and Federal regulations have been promulgated concerning the use and handling of US Department of Justice Drug Enforcement Administration (DEA) controlled substances. These regulations are in place to address materials which are or have the potential to be addictive or habit forming. These substances have been categorized into “schedules” that have been created by the DEA to reflect their level of concern. The “Carnegie Mellon University DEA Controlled Substances Program” is intended to ensure that Carnegie Mellon University is in compliance with our regulatory requirements. Required activities under the DEA include: 1. Registration of your work with the DEA and with Carnegie Mellon’s Department of Environmental Health and Safety (EH&S). -
Recreational Marijuana Legalization and Prescription Opioids Received by Medicaid Enrollees T ⁎ Yuyan Shia, , Di Lianga, Yuhua Baob, Ruopeng Anc, Mark S
Drug and Alcohol Dependence 194 (2019) 13–19 Contents lists available at ScienceDirect Drug and Alcohol Dependence journal homepage: www.elsevier.com/locate/drugalcdep Full length article Recreational marijuana legalization and prescription opioids received by Medicaid enrollees T ⁎ Yuyan Shia, , Di Lianga, Yuhua Baob, Ruopeng Anc, Mark S. Wallaced, Igor Grante a Department of Family Medicine and Public Health, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA b Department of Healthcare Policy and Research, Weill Cornell Medical College, 425 E 61stSt., New York, NY, 10065, USA c Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 1206 S 4thSt, Champaign, IL, 61820, USA d Department of Anesthesiology, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA e Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA ARTICLE INFO ABSTRACT Keywords: Objectives: Medical marijuana use may substitute prescription opioid use, whereas nonmedical marijuana use Marijuana may be a risk factor of prescription opioid misuse. This study examined the associations between recreational Opioid marijuana legalization and prescription opioids received by Medicaid enrollees. Recreational marijuana legalization Methods: State-level quarterly prescription drug utilization records for Medicaid enrollees during 2010–2017 Opioid prescription were obtained from Medicaid State Drug Utilization Data. The primary outcome, opioid prescriptions received, Medicaid was measured in three population-adjusted variables: number of opioid prescriptions, total doses of opioid prescriptions in morphine milligram equivalents, and related Medicaid spending, per quarter per 100 enrollees. Two difference-in-difference models were used to test the associations: eight states and DC that legalized re- creational marijuana during the study period were first compared among themselves, then compared to six states with medical marijuana legalized before the study period. -
19 CSR 30-1.042 Inventory Requirements
Rules of Department of Health and Senior Services Division 30—Division of Regulation and Licensure Chapter 1—Controlled Substances Title Page 19 CSR 30-1.002 Schedules of Controlled Substances .........................................................3 19 CSR 30-1.004 List of Excepted Substances.................................................................13 19 CSR 30-1.006 List of Exempt Anabolic Steroid Products................................................13 19 CSR 30-1.008 List of Excluded Veterinary Anabolic Steroid Implant Products......................14 19 CSR 30-1.010 Schedules of Controlled Substances (Rescinded November 30, 2000)...............14 19 CSR 30-1.011 Definitions......................................................................................15 19 CSR 30-1.013 Miscellaneous Fees ...........................................................................16 19 CSR 30-1.015 Registrations and Fees........................................................................16 19 CSR 30-1.017 Registration Process ..........................................................................16 19 CSR 30-1.019 Registration Location.........................................................................19 19 CSR 30-1.020 List of Excepted Substances (Rescinded November 30, 2000)........................19 19 CSR 30-1.023 Registration Changes .........................................................................19 19 CSR 30-1.025 List of Exempt Anabolic Steroid Products (Rescinded November 30, 2000).......20 19 CSR 30-1.026 -
Tennessee Drug Statutes (Listed in Numerical Order)
Tennessee Drug Statutes (listed in numerical order) 39-17-405. Criteria for Schedule I. • The commissioner of mental health and substance abuse services, upon the agreement of the commissioner of health, shall place a substance in Schedule I upon finding that the substance has: o (1) High potential for abuse; and o (2) No accepted medical use in treatment in the United States or lacks accepted safety for use in treatment under medical supervision. 39-17-406. Controlled substances in Schedule I. • (a) Schedule I consists of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. • (b) Opiates, unless specifically excepted or unless listed in another schedule, means any of the following opiates, including their isomers, esters, ethers, salts and salts of isomers, esters, and ethers, whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation. For the purposes of subdivision (b)(34) only, the term isomer includes the optical and geometric isomers. o (1) Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4- piperidinyl]-N-phenylacetamide); o (2) Acetylmethadol; o (3) Allylprodine; o (4) Alphacetylmethadol (except levo-alphacetylmethadol also known as levo-alpha-acetylmethadol; levomethadyl acetate; or LAAM); o (5) Alphameprodine; o (6) Alphamethadol; o (7) Alpha-methylfentanyl (N-[1-(alpha-methyl-beta-phenyl)ethyl-4- piperidyl]propionanilide; 1-(1-methyl-2-phenylethyl)-4-(N- propanilido)piperidine; -
Chapter 961 Uniform Controlled Substances Act
1 Updated 01−02 Wis. Stats. Database UNIFORM CONTROLLED SUBSTANCES ACT 961.01 CHAPTER 961 UNIFORM CONTROLLED SUBSTANCES ACT 961.001 Declaration of intent. 961.437 Possession and disposal of waste from manufacture of methamphetamine. SUBCHAPTER I 961.438 Minimum sentence. DEFINITIONS 961.44 Penalties under other laws. 961.01 Definitions. 961.45 Bar to prosecution. SUBCHAPTER II 961.455 Using a child for illegal drug distribution or manufacturing purposes. 961.46 Distribution to persons under age 18. STANDARDS AND SCHEDULES 961.465 Distribution to prisoners. 961.11 Authority to control. 961.47 Conditional discharge for possession or attempted possession as first of- 961.115 Native American Church exemption. fense. 961.12 Nomenclature. 961.472 Assessment; certain possession or attempted possession offenses. 961.13 Schedule I tests. 961.475 Treatment option. 961.14 Schedule I. 961.48 Second or subsequent offenses. 961.15 Schedule II tests. 961.49 Distribution of or possession with intent to deliver a controlled substance 961.16 Schedule II. on or near certain places. 961.17 Schedule III tests. 961.492 Distribution or possession with intent to deliver certain controlled sub- 961.18 Schedule III. stances on public transit vehicles. 961.19 Schedule IV tests. 961.495 Possession or attempted possession of a controlled substance on or near 961.20 Schedule IV. certain places. 961.21 Schedule V tests. 961.50 Suspension or revocation of operating privilege. 961.22 Schedule V. SUBCHAPTER V 961.23 Dispensing of schedule V substances. ENFORCEMENT AND ADMINISTRATIVE PROVISIONS 961.24 Publishing of updated schedules. 961.51 Powers of enforcement personnel. -
Alcohol and Drug Abuse Subchapter 9 Regulated Drug Rule 1.0 Authority
Chapter 8 – Alcohol and Drug Abuse Subchapter 9 Regulated Drug Rule 1.0 Authority This rule is established under the authority of 18 V.S.A. §§ 4201 and 4202 which authorizes the Vermont Board of Health to designate regulated drugs for the protection of public health and safety. 2.0 Purpose This rule designates drugs and other chemical substances that are illegal or judged to be potentially fatal or harmful for human consumption unless prescribed and dispensed by a professional licensed to prescribe or dispense them, and used in accordance with the prescription. The rule restricts the possession of certain drugs above a specified quantity. The rule also establishes benchmark unlawful dosages for certain drugs to provide a baseline for use by prosecutors to seek enhanced penalties for possession of higher quantities of the drug in accordance with multipliers found at 18 V.S.A. § 4234. 3.0 Definitions 3.1 “Analog” means one of a group of chemical components similar in structure but different with respect to elemental composition. It can differ in one or more atoms, functional groups or substructures, which are replaced with other atoms, groups or substructures. 3.2 “Benchmark Unlawful Dosage” means the quantity of a drug commonly consumed over a twenty-four hour period for any therapeutic purpose, as established by the manufacturer of the drug. Benchmark Unlawful dosage is not a medical or pharmacologic concept with any implication for medical practice. Instead, it is a legal concept established only for the purpose of calculating penalties for improper sale, possession, or dispensing of drugs pursuant to 18 V.S.A. -
New Drug Substances with Abuse Potential
New drug substances with abuse potential: Points to consider for the development and marketing - Regulatory environment in the European Union and the United States - Wissenschaftliche Prüfungsarbeit zur Erlangung des Titels „Master of Drug Regulatory Affairs“ der Mathematisch-Naturwissenschaftlichen Falkultät der Rheinischen Friedrich-Wilhems-Universität Bonn vorgelegt von Dr. Silke Jung Bonn 2006 Betreuer und 1. Referent: Dr. Winfried Kleinert, Bundesopiumstelle (BfArM) Zweiter Referent: RA Burkhard Stäter, Anwaltskanzlei Sträter To my husband - for his patience and support - Danksagung An erster Stelle möchte ich mich ganz herzlich bei Herrn Dr. Winfried Kleinert und Herrn RA Burkhard Sträter für die Betreuung und Unterstützung meiner Arbeit bedanken. Mein besonderer Dank gilt auch Herrn Dr. Joachim Heinze und Herrn Dr. Burkahrd Daldrup, die mir den Besuch des ergänzenden Studiengangs „Master of Drug Regulatory Affairs“ ermöglicht haben. Für die kritische Durchsicht meiner Arbeit und die vielen hilfreichen Anmerkungen danke ich meine Kolleginnen Dr. Gesine Bejeuhr, Dr. Kim Goldenstein, Dr. Maren Großmüller, Dr. Carol Huntington und Dr. Barbara Römer. Besonderer Dank gilt nicht zuletzt auch meiner Familie, vor allem meinem Mann Dr. Guido Thömmes, die meine Arbeit mit Liebe und Unterstützung begleitet hat. TABLE OF CONTENTS A1 Table of contents Table of contents......................................................................................................................... A1 Abbreviations............................................................................................................................. -
(19) United States (12) Patent Application Publication (10) Pub
US 20030077300A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2003/0077300 A1 Wermeling (43) Pub. Date: Apr. 24, 2003 (54) SYSTEM AND METHOD FOR INTRANASAL Publication Classi?cation ADMINISTRATION OF OPIOIDS (51) Int. Cl.7 ........................ ..A61K 31/485; A61L 9/04; (76) Inventor: Daniel P. Wermeling, Lexington, KY A61K 9/00 (US) (52) US. Cl. ........................... .. 424/400; 424/45; 514/282 Corres ondence Address: Kalowp& Springut LLP (57) ABSTRACT 19th Floor . 488 Madison Avenue The invention relates to pharmaceutical drug compositions New York, NY 10022 (Us) and preparations that are narcotic antagonists and analge sics, speci?cally opioids, more speci?cally morphine and its (21) APPL NO: 10/155’624 pharmaceutically active derivatives, analogues, homo logues, and metabolites, and still more speci?cally hydro (22) Filed; May 24, 2002 morphone and butorphanol. This invention also relates to pharmaceutical drug delivery devices, speci?cally to devices for the intranasal administration of drugs classi?ed as con Related US, Application Data trolled substances. The invention also relates to the ?eld of acute pain management through pharmaceutical interven (63) Continuation of application No. 09/569,125, ?led on tion, particularly as practiced in an institutional setting, such May 10, 2000. as a hospital. Patent Application Publication Apr. 24, 2003 Sheet 1 0f 5 US 2003/0077300 A1 Patent Application Publication Apr. 24, 2003 Sheet 2 0f 5 US 2003/0077300 A1 m2:@505 ooow Sow wllooow coo?ll (1w/6d) 'ONOO vwsvw Patent Application Publication Apr. 24, 2003 Sheet 4 0f 5 US 2003/0077300 A1 .@Iw oooi ooowv 0002 ooow ooow Sow Patent Application Publication Apr.