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BIOPHARMA CAMPUS IRELAND BIOPHARMA CAMPUS IRELAND ORANMORE GALWAY ORANMORE GALWAY with Unparalleled Flexibility

A world-first: A pre-approved fully permitted Biopharma campus BIOPHARMA CAMPUS BIOPHARMA CAMPUS IRELAND ORANMORE GALWAY with unparalleled flexibility

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Letterkenny What is the competitive advantage? Galway offers: Construction Ready Site Excellent skills availability BIOPHARMA CAMPUS IRELAND . Enniskillen r eddog Allows delayed Investment Decision by 1 year minimum Airport .ie

Castlebar Significantly removes risks to Project Mainline Rail Photos: Kylemor Longford ORANMORE GALWAY Westport Knock Welcome by Local Agencies and Environment Motorway Link Roscommon All technical issues identified and solved in advance National University of Ireland, Galway Galway e Abbey & landscape: T High Quality Manufacturing Environment supported and 3rd Level Technology Institute SITE Kildare by a University City High quality of life Shannon Wicklow Low Corporate Tax

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Clonmel eland Imager Rosslare y Killarney The Global location of choice for the Biopharma industry . Galway Hooker: Fáilte Ir eland. NUI: cour

…already home to the world’s leading pharmaceutical companies tesy of NUI Galway .

Head Office USA Europe Japan IDA Ireland 345 Park Avenue, 17th Floor Germany Ireland House 2F Wilton Place New York, Bockenheimer Landstraße 39 2-10-7 Kojimachi Dublin 2 NY 10154-0004 D-60325 Frankfurt a.M Chiyoda-Ku Ireland Tokyo 102-0083

Tel: + 353 1 603 4000 Tel: (212) 750 4300 Tel: (69) 70 60 99-0 Tel: (3) 3262 7621 Fax: + 353 1 603 4040 Fax: (212) 750 7357 Fax: (69) 70 60 99-70 Fax: (3) 3261 4239 Email: [email protected] Web: www.idaireland.com

Your company can construct its own unique Biopharma Campus NOW. This flexibility is your answer to fast Technical Specifications entry to the Biopharma market. Phase 2 Phase 1

7 8 7 6 8 8 5 6 6 5 5 Warehouse 1 4 2 5 6 3 1 Fil Fer 1 2 7

l F 4

2 men

inish 3 8 2 1 tati Admin Warehouse/ Water purificationon Flexibility is delivered in four ways: 2 Flexibility Build out options building 1300m2 Waste water Dispensary 3700m Phase 2 Phase 1 treatment building 34m high bulk fermentation Phase 2 Phase 1 3 storey building 10500m2 Planning permission (permit) has been achieved The planning permission (permit) imposes no restrictions on A full site development C medium fermentation E large scale fill finish (only) Docks Combined utility 2 7 Fill finish 4800m 2 8 7 Combined utility Electrical high building 1300m for a fully integrated facility including all internal layouts or process configurations including 7 8 6 7 8 Phase 2 PhasePhase 1 2 Phase 1 2 Laboratory & admin 8 6 5 5 5 building 1300m tension building 5 6 6 8 8 2 Biotechnology operations the number of floors or floor levels within the buildings. 5 6 5 6 Warehouse building 4000m 5 1 1 4 2 5 5 4 5 6 Warehouse 4 3 7 7 1 Fil 3 Fer 3 3 4 1 8 8 7 2 7 2 2 2 1 2 l F 4 7 5 6 men 3 6 1 Fil 8 Fer 8 8 8

6 inish 2 3 8 5 1 2 6 6l F 4 7 6 6

5 men

Bulk fermentation Any combination of buildings or a selected subset of these 2 tati 5 215 inish 3 8 5 5 Warehouse Warehouse

1 1 on 4 4 2 2 Admin 21 tati 5 6 5 6 Fil Fer Harvest and purification buildings can be built. Your campus can be as little as 50,000 3 3 1 1 Fil Fer Admin 2 7

1 l F 1 2 l F 4 4 7 on men 2 2 men inish Sterile fill finish sq. ft or as much as 500,000 sq. ft (approx). inish 3 8Start-up3 2+38 only 21

21tati tati All necessary support functions: Admin Admin on on warehousing Full flexibility in the layout or disposition of items of internal B large scale fermentation (only) D small scale fermentation F small fill finish Phase 2 Phase 1 + start-up 2&3 only laboratories or external plant or equipment is allowed. 5 5 (perfusion5 technology) 5 5 5 waste water and water treatment facilities 4 4 1 7 3 3 3 8 24 7 24 1 2 The approved building can accommodate 5,000 to 50,000 litres 3 8 3 8 3 H.T. electricity and natural gas 6 2 2 5 5 2 5 5 6 6 5 5 5 5 5 Warehouse fermentation capacity as well as fill finish activities ranging 1 1 1 4 2 4 4 5 6 4 4

3 Fil Fer 3 3 3 1 2 3 2 2 3 2 2 3 2 The facility is designed to be a flexible multi-product, multi- from vials, syringes and ampoules with or 1 2 l F 4 7 2 men Start-upinish 3 2+38 only process campus suitable for a range of investors, principally without lyophilisation. 21tati Start-up 2+3 only

Phase 2 Phase 1 Admin on multi-national Biopharmaceutical Corporations. Start-up 2+3Start-up only 2+3 only

The 67 acre site is situated in Oranmore, Co.Galway. 7 8 7 8 8 6 5 5 5 The planning permit specifically provides sufficient 5 6 Typical options 6 1 2 3 4 5 6 7 8 Technical Brief Competitive Edge design and layout flexibility enabling the nature 5 4 4 5 1 Warehouse 3 2 A full site3 development2 3 2 1 Bio Reactor Capacity A unique proposition offering an instant start on site thereby and scope of the advance Campus to be tailored 4 2 B large scale fermentation 5 6 Fer 3 1 Fil for any biopharma investor. l F up to 50,000 litres saving considerable planning time, expense

1 C medium fermentation 2 4 7 men

2 inish D small scale fermentation 3 8 Fill Finish Capacity and ultimately reduced time to market.

Start-up 2+3 only tati E large scale fill finish only 21 Up to 3 lines of vials, syringes ampoules on F small fill finish + Admin (including Lyophilisation) start-up 2–3 only Utilities Capacity 2000m3/day water in and water out HT Electricity up to 20mva(+/-)

5 5 5

4 4 1 3 2 3 2 3 2

Start-up 2+3 only