Table 1. List of Peptide Sequences Common for Conventional and Organic Ham DPP-IV Sequence1 Protein Position2 ACE Inhibitor Stimulating3 Antioxidant Inhibitor

Table 1. List of peptide sequences common for conventional and organic ham DPP-IV Sequence1 Protein Position2 ACE inhibitor Stimulating3 Antioxidant inhibitor

Sarcoplasmic/endoplasmic [783- LP,LL, IP, AL, 1 G.LPEALIPVQLL.W4 IP, EP LI, LL - reticulum calcium ATPase 793] LI, PV, QL, VQ

GA, IA, AL, Glyceraldehyde-3- [296- VK, IA, GI, GA, 2 A.GAGIALNDHFVK.L5 AG, GI, HF,LN, - - phosphate dehydrogenase 307] AG, LN ND, VK

PP, VP, VV, [141- VP, GA, PG, 3 L.PPVVPVSKPGALR.R6 Telethonin KP, GA, AL, - KP 153] KP, PP, LR PG, PV, SK, VS

Sarcoplasmic/endoplasmic [975- IG, GL, KF, EI, LP, GL, EI, IL, 4 S.LPVIGLDEILKF.V7 IL LK reticulum calcium ATPase 986] IL KF, PV, VI

Sarcoplasmic/endoplasmic [975- LP, LL, GL, KF, 5 S.LPVIGLDELLKF.I8 IG, GL, KF LL EL, LK reticulum calcium ATPase 986] PV, VI

Actin, alpha skeletal [244- LP, NE, QV, TI, 6 E.LPDGQVITIGNER.F9 IG, GQ, DG - - muscle 256] VI

GA, IA, AL, Glyceraldehyde-3- [294- VK, IA, GA, GI, AG, GI, HF, 7 F.DAGAGIALNDHFVK.L - - phosphate dehydrogenase 307] AG, DA, LN LN, ND, VK, DA, HF

GP, EG, KE, Cytochrome c oxidase GP, EG, KL, 8 N.VDYSKLKKEGPDF,-10 [70-82] KK, SK, VD, - LK subunit NDUFA4 KE, DY, DF YS

VA, EP, AE, VK, KG,GT, ES, KE, KG, 9 F.VAEPKESFVKGTVQS.R11 Myosin-1 [40-54] - - SF, KE PK, QS, SF, TV, VK, VQ EP, TA, VR, [438- 10 R.VREPVISAVEQTAQR.T Titin VR, VE, AV AV, PV, QT, - - 452] VE, VI

VV, HA, TP, EI, [6063- 11 S.VVDTPEIIHAQQVKN.L12 Nebulin VK, EI, TP IH, II, QQ, QV, II - 6077] VD, VK

GP, EG, KE, Cytochrome c oxidase GP, EG, KL, 12 S.VNVDYSKLKKEGPDF.-13 [68-82] KK, NV, SK, - LK subunit NDUFA4 KE, DY, DF VD, VN, YS

AY, AA, KA, EP, AA, [5525- DA(2)14, YK, 13 T.IEPDAVHIKAAKDAYK.V15 Nebulin AV, AY, HI, - AY, KD 5540] KA, IE, IEP, VH, YK AV

KA, VP, VV, IR, VPK, AF, [512- EK, AF, ET, IR, 14 Q.IRKETEKAFVPKVVIS.A16 Titin VP, KA, TE, - IR 527] KE, KV, PK, EK, KE, FVP RK, TE, VI

GP, AG, EY, Actin, alpha skeletal [360- GP, AG, EA, HR, PS, QE, 15 I.TKQEYDEAGPSIVHRK.C17 IV - muscle 375] EY, AGP RK, SI, TK, VH, YD

PR, VP, RA, VP, RA, EI, IQ, 16 L.SEIQNIKSELKYVPRA.E18 Small muscular protein [69-84] YVP, KY, EI, KS, KY, QN, SE(2) EL, LK YV YV

VV, HA, TP, EI, [6061- IH, II, QQ, QV, 17 F.TSVVDTPEIIHAQQVKN.L Nebulin VK, EI, TP II - 6077] SV, TS, VD, VK

AP, EA, EV(3), Troponin T, fast skeletal 18 E.EAPPPPAEVHEVHEEVH.E19 [22-38] PP(3), EAP, PPPP, PP(3), EE - muscle PPP(3) AP, PA, AE, EV(3), HE(2), VH(3)

EP, TA, VR, [436- VR, AR, VE, 19 M.ARVREPVISAVEQTAQR.T20 Titin AV, PV, QT, - - 452] AV, RVR VE, VI

GA, IA, AL, VK, IA, GI, GA, Glyceraldehyde-3- [290- AG, GI, HF, 20 H.SSTFDAGAGIALNDHFVKL.I21 AG, DA, KL, - VKL phosphate dehydrogenase 308] LN, ND, TF, LN, TF, ST VK

GP, AG, EY, Actin, alpha skeletal [359- GP, AG, EA, HR, PS, QE, 21 W.ITKQEYDEAGPSIVHRK.C22 IV - muscle 375] EY, AGP RK, SI, TK, VH, YD

GP, ES, EY, POTE ankyrin domain [1057- GP, SG, EY, HR, PS, QE, 22 W.ISKQEYDESGPSIVHRK.C23 IV - family member 1073] SGP RK, SI, SK, VH, YD

VV, HA, TP, EI, [6060- IH, II, QQ, QV, 23 N.FTSVVDTPEIIHAQQVKN.L24 Nebulin VK, EI, TP II - 6077] SV, TS, VD, VK

VAP, LNP, PL, VA, AP(2), LL, Actin, aortic smooth AP, EA, TE, HP, NP, PL, 24 L.RVAPEEHPTLLTEAPLNPK.A25 [97-115] LL, EE - muscle LN, PTM HP, EH, LN, PK, EAP PT, TE, TL

KA, AD, GY, [1052- GY, KG, YK, 25 M.YKADLKDLSKKGYDLRTD.A26 Nebulin KG, KK, SK, - KD, LK 1069] KA, LR TD, YD, YK

[696- VA(2), KA, VV, 27 VAA, AA, VG, 26 G.VGKKAEAVATVVAAVDQARVR.E Titin VR, AA, AE, - - 716] GK, EA, VR, AT, AV(2), DQ, AR, KA, AV(2), KK, QA, TV, RVR VD, VG

GP, WI, AG, Actin, alpha skeletal [358- GP, AG, EA, EY, HR, PS, 27 M.WITKQEYDEAGPSIVHRK.C28 IV - muscle 375] EY, AGP QE, RK, SI, TK, VH, YD

MA, EP, TA, [432- VR, AR, VE, 28 A.AVDMARVREPVISAVEQTAQR.T29 Titin VR, AV, PV, - - 452] AV, DM, RVR QT, VD, VE, VI

LIM domain-binding FP, AL, AG, FP, AG, GH, protein [668- GH, HD, HT, 29 C.DFPVEAGDKFIEALGHTWHDT.C30 LG, GD, EA(2), - TW 689] KF, PV, TW, KF, EI, VE, DF VE, WH

KA, VV, HA, TP, EK, EI, IH, [6055- VK, NF, KA, 30 E.MEKANFTSVVDTPEIIHAQQVKN.L31 Nebulin II, ME, NF, QQ, II - 6077] EI, ME, EK, TP QV, SV, TS, VD, VK

PP(2), KA, AP, FP, LSP, AY, LP, LL, SP, FP, PL, IA, AP, AA, Synaptopodin 2-like [807- IA, NP, AA, PL, 31 R.APPPIAYNPLLSPFFPQAARTLPKAQ.S32 AR, KA, PP(2), LL AY protein 832] AY, PF, PI, PK, PQ, IAY, PPP, PQ, QA, TL, YN YN

YG, LAY, AY, KA, LA, LP, LA, GI, GA, LL, GA, AE, [192- GV, LG, QK, AY, DP, GI, AY, EL(2), 32 M.GVDPHQKVELGIDLLAYGAKAELPQYK.S33 Myozenin-1 LL 206] YK, KA, VE, GV, KV, PH, PHQ PQ, PH, LGI, PQ, QY, VD, AEL VE, YG, LPQ RA, FL(2), AL, Isocitrate dehydrogenase VK, RA, GR, DR, EH, HF, [394- 33 N.VKLNEHFLNTSDFLDTIKSNLDRALGRQ.-34 [NADP], mitochondrial LG, KL, LN(2), KS, LN(2), NE, - SDF, VKL 421] (Fragment) DF NL, NT, TI, TS, VK,

1 sign (.) indicate cutting points 2 position in parental protein 3 stimulating vasoactive substance release or glucose uptake stimulating peptide 4 other activity: alpha-glucosidase inhibitor – EA; dipeptidyl peptidase III inhibitor – PE 5 other activity: dipeptidyl peptidase III inhibitor – HF 6 other activity: antiamnestic, antithrombotic, regulating the stomach mucosal membrane activity – PG; alpha-glucosidase inhibitor – PP; dipeptidyl peptidase III inhibitor – HF; renin inhibitor - LR 7 other activity: CaMPDE inhibitor, renin inhibitor – KF 8 other activity: CaMPDE inhibitor, renin inhibitor – KF 9 other activity: neuropeptide – GQ 10 other activity: antiamnestic, antithrombotic – GP; regulating ion flow – DY; regulating the stomach mucosal membrane activity – GP; bacterial permease ligand – KK; 11 other activity: renin inhibitor – SF 12 other activity: dipeptidyl peptidase III inhibitor – IH, PE 13 other activity: antiamnestic, antithrombotic – GP; regulating ion flow – DY; regulating the stomach mucosal membrane activity – GP; bacterial permease ligand – KK 14 the number in () indicates the number of identified peptides, if more than one 15 other activity: dipeptidyl peptidase III inhibitor – YK, DA(2) 16 other activity: dipeptidyl peptidase III inhibitor – KA; CaMPDE inhibitor and renin inhibitor - IR 17 other activity: antiamnestic, antithrombotic – GP; regulating the stomach mucosal membrane activity – GP; alpha-glucosidase inhibitor – EA 18 other activity: activating ubiquitin-mediated proteolysis – RA; dipeptidyl peptidase III inhibitor – PR 19 other activity: dipeptidyl carboxypeptidase inhibitor – PPPA; alpha-glucosidase inhibitor – EA, PP(3) 20 other activity: dipeptidyl peptidase III inhibitor – RV 21 other activity: dipeptidyl peptidase III inhibitor – TF, DA, HF; renin inhibitor – TF 22 other activity: antiamnestic, antithrombotic, regulating the stomach mucosal membrane activity – GP; alpha-glucosidase inhibitor - EA 23 other activity: antiamnestic, antithrombotic, regulating the stomach mucosal membrane activity – GP 24 other activity: dipeptidyl peptidase III inhibitor – IH, PE; renin inhibitor - FT 25 other activity: dipeptidyl peptidase III inhibitor – RV, HP, PE; alpha-glucosidase inhibitor – EA 26 other activity: dipeptidyl peptidase III inhibitor – LR, YK, KA; renin inhibitor - LR; bacterial permease ligand – KK 27 other activity: dipeptidyl peptidase III inhibitor – RV, KA; bacterial permease ligand - KK; alpha-glucosidase inhibitor – EA 28other activity: antiamnestic, antithrombotic, regulating the stomach mucosal membrane activity – GP 29 other activity: dipeptidyl peptidase III inhibitor – RV 30other activity: alpha-glucosidase inhibitor – EA(2); CaMPDE inhibitor and renin inhibitor – KF 31other activity: dipeptidyl peptidase III inhibitor – IH, PE, KA; renin inhibitor – FT 32other activity: dipeptidyl peptidase III inhibitor – PF, KA; alpha-glucosidase inhibitor – PP(2) 33other activity: dipeptidyl peptidase III inhibitor – YK, LA, YG, KA; immunomodulating - YG; activating ubiquitin-mediated proteolysis – LA 34other activity: dipeptidyl peptidase III inhibitor – HF, FL(2); activating ubiquitin-mediated proteolysis - RA Table 2. List of peptide sequences common for conventional and organic loins

Stimulating Antioxidan Sequence1 Protein Position2 ACE inhibitor DPP-IV inhibitor 3 t

LP, IP, SK, PL, PH, LIM domain-binding 1 Q.SPLPVIPHQK.D [98-107] PLP, PL, IP, QK, PH - PHQ protein 3 PV, VI

Sarcoplasmic/endopl asmic reticulum LP, LL, IP, AL, LI, 2 [11-21] IP, EA LI, LL calcium ATPase 3 PV, QL, VQ G.LPEALIPVQLL.W4 (Fragment)

PP, LP, VP, VV, [139- LPP,VP, GA, PG, KP, 3 K.LPPVVPVSKPGALR.R6 Telethonin KP, GA, AL, PG, - KP 153] PP, LR PV5, SK, VS

[259- PP, FA, KK, KV, 4 D.PPDIEFAKKVTNQ.V7 Nebulin AKK, IE, PP - - 271] NQ, TN, VT

PP, LP,VP, VV, KP, [139- LPP,VP, GA, PG, KP, 5 K.QLPPVVPVSKPGALR.R8 Telethonin GA, AL, PG, PV(2), - KP 153] PP,LR QL, SK, VS

PP(2), PA, AE, Troponin T, fast 6 P.PPPAEVHEVHEEVH.E9 [25-38] EV(3), PP(2), PPP EV(3), HE(2), EE KP skeletal muscle VH(3)

VA, EP, AE, ES, 7 Myosin-1 [40-54] VK, KG, GT, SF, KE KE, KG, PK, QS, - - F.VAEPKESFVKGTVQS.R10 SF, TV, VK, VQ

IA, AS, AT, KY, [6038- 8 Nebulin IA, KY, YK, IKY NA, QI, RN, TD, - - 11 6051] A.RNATDIASQIKYKQ.S YK [240- GPL, LGP, GP, PL(2), GP, ML, LL, EP, 9 Q.MPKFDLGPLLSEPLV.L12 Myozenin-1 LV, LL, SE - 254] LG, KF, DLGP PL(2), KF, LV, PK,

Musculoskeletal GP, KA, PA, KP, GPA, VF, GP, AG, 10 E.TVFEKPKAGPAKSVFG.-13 embryonic nuclear [67-82] GPA, EK, AG, KS, - KP FG, KA, KP, EK, AGP protein 1 PK, SV, TV, VK(2)

[438- EP, TA, VR, AV, 11 R.VREPVISAVEQTAQR.T Titin VR, VE, AV - - 452] PV, QT, VE, VI

VV, HA, TP, EI, IH, [6063- 12 S.VVDTPEIIHAQQVKN.L14 Nebulin VK, EI, TP II, QQ, QV, VD, II - 6077] VK, IH

IA, AS, AT, KY, [6037- 13 R.ARNATDIASQIKYKQ.S15 Nebulin IA, KY, YK, AR, IKY NA, QI, RN, TD, - - 6051] YK

[5525- AY, AA, DA(2), YK, KA, EP, AA, AV, 14 T.IEPDAVHIKAAKDAYK.V16 Nebulin - AY, KD 5540] KA, IE, IEP, AV AY, HI, VH, YK

PPPP, PP(3), AP, Troponin T, fast AP, EV(3), PP(3), 15 [28-38] PA, AE, EV(3), EE - 17 skeletal muscle PPP(2) E.APPPPAEVHEVHEEVH.E HE(2), VH(3)

KA, VP, VV, EK, [512- IR, VPK, AF, VP, KA, 16 Q.IRKETEKAFVPKVVIS.A18 Titin AF, ET, IR, KE, - IR 527] TE, EK, KE, FVP KV, PK, RK, TE, VI

Glyceraldehyde-3- VK, IA, GI, GA, GA, AL., IA, AG(2); [290- 17 H.SSTFDAGAGIALNDHFVK.L19 phosphate AG(2), DA, LN, TF, GI, HF, LN, ND, - - 307] dehydrogenase ST TF, VK,

[5524- AY, AA, DA(2), YK KA, EP, AA, AV, 18 C.TIEPDAVHIKAAKDAYK.V20 Nebulin - AY, KD 5540] KA, IE, IEP, AV AY, HI, TI, VH, YK VV, HA, TP, EI, IH, [6061- 19 F.TSVVDTPEIIHAQQVKN.L21 Nebulin VK, EI, TP II, QQ, QV, SV, TS, II - 6077] VD, VK

LA, VP, LL, TP, [5630- AVP, LA, VP, PQ, 20 H.AVPDTPQILLAKTVSNLV.S22 Nebulin AV, IL, KT, LV, LV, IL, LL - 5647] AV, TP, IL NL,PQ, QI, TV, VS

GP, KA, PA, GPA, GPA, LGP, GP, LKA, AL, AV, EH, GV, 21 G.KGVLKAVEHINKTLGPAL.L23 Beta-enolase [60-77] KG, GV, LG, NK, AK, VL LK HI, IN, KG, KT, TL, VE, AV VE, VL

LA, AA, AS, IL, [248- LAA, LA, AA, EA, 22 Apolipoprotein A-I KK, KV, LN, NA, IL - 24 265] KL, LN, AI, IL L.KVSILAAIDEASKKLNAQ.- SI, SK, VS

PPPP, PP(3), AP, Troponin T, fast AP, EA, EV(3), PP(3), 23 E.EAPPPPAEVHEVHEEVH.E25 [22-38] PA, AE, EV(3), EE - skeletal muscle EAP, PPP(2), HE(2), VH(3)

[436- VR, AR, VE, AV, EP, TA, VR, AV, 24 M.ARVREPVISAVEQTAQR.T26 Titin - - 452] RVR PV, QT, VE, VI

KA, HA, EH, KK, [153- 25 E.KAKDIEHAKKVSQQVSK.V27 Nebulin AKK, KA, IE KV, QQ, QV, SK, - KD 169] VS(2)

VV, AT, ET, EV, [451- GE, EA, DG, IE, EV, 26 T.IETRDGEVVSEATQQQH.E28 Desmin GE, QH, QQ(2),TQ, - SE 467] TQ TR, VS

SP, FP, RA, AG, VF, FP, PR, RA, GF, 27 S.SPVFPRAGFGTKGSSSSVTS.R29 Desmin [32-51] GF, KG, PV, SV, SSS(2) - AG, KG, FG, GS, GT TK, TS, VF, VT

VAP, LNP, PL, AP(2), VA, AP(2), LL, HP, 28 R.VAPEEHPTLLTEAPLNPK.A30 Actin, alpha skeletal [98-115] EA, TE, LN, PT, HP, NP, PL, EH, LN, LL, EE - muscle EAP LT, PK, PT, TE, TL Troponin T, fast [160- GM, GR, SG, EG, IE, EK, WRK, WR, EG, 29 G.DWRKNIEEKSGMEGRK.K EE - skeletal muscle 175] ME, EK KS, ME, RK

Glyceraldehyde-3- VK, IA, GI, GA, GA, IA, AL, AG, [290- 30 H.SSTFDAGAGIALNDHFVKL.I31 phosphate AG(2), DA, KL, LN, GI, HF, LN, ND, - VKL 308] dehydrogenase TF, ST TF, VK

TP, EH, HH, KE, Protein phosphatase VE, LQ, PT, KE, TP, HH, EL, 31 T.RTTPTMKELQMMVEHH.L [76-91] MK,MM, MV, PT, - 1 regulatory subunit MM EHH, MM TM, TT, VE

GP, AG, EY, HR, Actin, alpha skeletal [359- 32 W.ITKQEYDEAGPSIVHRK.C32 GP, AG, EA, EY, AGP PS, QE, RK, SI, TK, IV - muscle 375] VH, YD

MA, AP, LP, IP, PL, PDZ and LIM [169- LPG, PL, VK, IP, AP, 33 K.MAPNIPLEMELPGVKIVH.A33 GV, KI, ME, PG, IV EL domain protein 186] GV, PG, ME, MAP PN, VH, VK

VV, HA, TP, EI, IH, [6060- 34 N.FTSVVDTPEIIHAQQVKN.L34 Nebilin VK, EI, TP II, QQ, QV, SV, TS, II - 6077] VD, VK,

VV, AT, ET, EV, [450- GE, EA, DG, IE, EV, 35 K.TIETRDGEVVSEATQQQH.E35 Desmin GE, QH, QQ, TI, SE - 467] TQ TQ, TR, VS

EK, EV, EY, KE, [6007- VK, KR, GR, KG, YK, 36 Nebulin KG, KR, NE, RG, - EL 36 6023] EY, EV, EK, KE, RG N.NEKEYKRDLELEVKGRG.N VK, YK

Troponin T, fast [160- GM, GR, SG, EG, IE, EK, WRK, WR, EG, 37 37 EE - G.DWRKNIEEKSGMEGRKK.M skeletal muscle 176] ME, EK KK, KS, ME, RK(2)

KA, VP, VV, EK, [510- IR, VPK, AF, VP, KA, AF, ET, IR, KE, 38 H.EQIRKETEKAFVPKVVIS.A38 Titin IR 527] TE, EK, KE, FVP KV, PK, QI, RK, TE, VI VAP, LNP, PL, AP(2), VA, AP(2), LL, HP, Actin, alpha skeletal 39 L.RVAPEEHPTLLTEAPLNPK.A39 [97-115] EA, TE, LN, PT, HP, NP, PL, EH, LN, LL, EE - muscle EAP LT, PK, PT, TE, TL

KA, AD, GY, KG, [1052- 40 M.YKADLKDLSKKGYDLRTD.A40 Nebulin GY, KG, YK, KA, LR KK, SK, TD, YD, - KD, LK 1067] YK

VA(2), KA, VV, VAA, AA, VG, GK, [696- VR, AA, AE, AT, 41 G.VGKKAEAVATVVAAVDQARVR.E41 Titin EA, VR, AR, KA, - - 716] AV(2), DQ, KK, AV(2), RVR QA, TV, VD, VG

GP, WI, AG, EY, Actin, alpha skeletal [358- 42 M.WITKQEYDEAGPSIVHRK.C42 GP, AG, EA, EY, AGP HR, PS, QE, RK, SI, IV muscle 375] TK, VH, YD

ES, EY, KE, KG, [5933- GR, KR, GK, SG, EY, 43 Q.SGKEYRKDYEESIKGRNL.T43 Nebulin NL, RK, RN, SI, EE KD 5950] KE, DY, YE YE, YR

ES, EY, KE, KG, [5933- GR, KG, GK, SG, TG, 44 Q.SGKEYRKDYEESIKGRNLTG.L44 Nebulin LT, NL, RK, RN, SI, EE KD 5952] EY, KE, DY, YE TG, YE, YR

KA, HA, EK, EH, [149- 45 C.HVDEKAKDIEHAKKVSQQVSK.V45 Nebulin AKK, KA, IE, EK, KD HV, KK, KV, QQ, - KD 169] QV, SK, VD, VS(2)

VF, FP(2), PR, PLG, AP, SP(2), FP(2), PL(2), AP, RA, GF, GA, RA, PL(2), AG, 46 F.GGAPSFPLGSPLSSPVFPRAGFGTK.G46 Desmin [19-43] - - GA, AG, FG, GS, GT, GF, GG, PS, PV, SF, GG, LG, SF TK, VF

PA, HP, AA(2), AT, T-complex protein 1 AA(2), DA, EV, HP, 47 L.FVTNDAATILRELEVQHPAAKM.I47 [64-85] EV, IL, ND, QH, TI, IL EL subunit theta IL, LR TN, VQ, VT PR, VK, RP, AP, IF, PPPP(4); PP(6), AP, [11805- PAP, PPK, KP, PP(6), PA, RP, KP, EK, 48 L.KPRPPPPPPAPPKEDVKEKIFQ.L48 Titin - KP 11826] EK, KE(2), PAPPK, FQ, KE(2), KI, PK, RPP, FQ, PPP(4) VK

RF, VAA, AA, GK, VA, KA, FL, VR, Phosphoglycerate [231- 49 M.RFLGDEETVRKAMEAVAAQGKAK.-49 QG, LG, GD, EA, VR, AA, AV, ET, ME, EE - mutase 2 253] KA(2), ME, AV QG, RK, TV

SP, FP, RA, AG, VF, VY, FP, PR, RA, GF, KG, PV, SV, 50 L.SSPVFPRAGFGTKGSSSSVTSRVYQ.V50 Desmin [31-55] GF, AG, KG, FG, GS, SSS(2) VY TK, TS, VF, VT, GT, RVY VY, YQ

KA, VV, HA, TP, [6055- VK, NF, KA, EI, ME, EK, EI, IH, II, ME, 51 E.MEKANFTSVVDTPEIIHAQQVKN.L51 Nebulin II - 6077] EK, TP NF, QQ, QV, SV, TS, VD, VK

PP(2), AP, LP, LL, FP, LSP, AY, PL, IA, Synaptopodin 2-like [807- SP, FP, IA, NP, AA, 52 R.APPPIAYNPLLSPFFPQAARTLPK.A52 AP, AA, AR, PP(2), LL AY protein 830] PL, AY, PF, PI, PK, PQ, IAY, PPP, YN PQ, QA, TL, YN

GA, AL, GL(2), AA, Ubiquinone AA, GA, GL(2), MG, AV, GE, LM, LN, [292- 53 STGEALVQGLMGAAVTLKNLTGLNQRR53 biosynthesis protein GE, QG, TG(2), EA, LT, LV, MG, NL, LV LK, GAA 318] COQ9 RR, LN, AV, LVQ, ST NQ, QG, RR, TG(2), TL, VQ, VT

MA VV, WY, AS, Glyceraldehyde-3- DN, GY, KE, LM, [314- 54 SWYDNEFGYSNRVVDLMVHMASKE54 phosphate GY, FG, KE MV, NE, NR, SK, - WY 321] dehydrogenase SW, VD, VH, YD, YS

Y.MLTDRENQSILITGESGAGKTVNTKRVI [164- KR, GA, AG, GK, GE, GA, AG, DR, ES, 55 Myosin-6 IL, LI - Q.Y55 192] SC, TG, IL GE, IL, IQ, KR, KT, LI, LT, ML, NQ, NT, QS, SI, TD, TG, TK, TV, VI, VN

TP, SP, TA, KE, LV, VSP, VK, IG, GK, F.SSVLYKEDVSPGTAIGKTPEMMRVKQT [6150- KT, MM, MR, PG, 56 Nebulin GT, PG, YK, TQ, KE, VL LY, MM QDH.I + Oxidation (M)56 6179] QD, QT, SV, TQ, AI, VLY, TP, MM VK, VL, VS, YK

VA, SP, YP, SL, LY, LF, FY, YP, EA, YPY, WE, YT, AD, F.SKKLYTEDWEADKSLFYPYNDSPELRR [203- LY, EL, 57 Nebulin QK, KL, RR, TE, YN, KK, KS, ND, PY, - VAQAQK.A57 235] PEL LR QA, RR, SK, TE, YN

[5956- PA, LL, TP, AL, 58 V.TPALLHVKYA.T58 Nebulin VK, YA, KY, TP LL LH, LHV 5965] HV, AY,

Glyceraldehyde-3- [298- IA, AL, GI, HF, LN, 59 A.GIALNDHFVK.L59 phosphate VK, IA, GI, LN 307] ND, VK dehydrogenase

PA, LL, TP, AL, [5955- 60 Nebulin VK, YA, KY, TP HV, KY, LH, VK, LL LH, LHV 60 5965] E.VTPALLHVKYA.T VT, YA

[10153- VK, VP, IE, EV(2), PA, VP, AV, EV(2), 61 Titin - VKV E.EVIEVKVPAVH.T 10163] AV KV, VH, VI, VK

Glyceraldehyde-3- KA, GA(2), HL, EK, [103- GA(2), AG, HL, KG, HL, AH, 62 phosphate AG, AH, GG, KG, - 61 115] GG, KA, AH, ME, EK GAH, LK T.MEKAGAHLKGGAK.R dehydrogenase ME

[1313- AIP, IA, IP, AA, DA, IPI, KA, IP, IA, TA, 63 62 Nebulin - - G.DAIPITAAKASRNIA.S 1327] KA, AJ AA, AS, PI, RN

EK(2), KE(2), [5898- VK, KY(2), YK, 64 Q.SIVKYKEKYEKE.R63 Nebulin KY(2), SI, VK, YE, IV - 5909] EK(2), KE(2), YE YK Troponin I, fast [160- GM, SG, EG, IE, ME, EK, WRK, WR, EG, 65 G.DWRKNIEEKSGMEG.R EE - skeletal muscle 173] EK KS, ME, RK

SP(2), FP, RA, PL, VF, FP, PR, PL, RA, 66 G.SPLSSPVFPRAGFGTKG.S64 Desmin [28-44] AG, GF, KG, PV, - - GF, AG, KG, FG, GT TK, VF

EK, SL, DN, GV, Glyceraldehyde-3- [136- 67 GV, KY, EK HE, KI, KY, NH, IV LK M.GVNHEKYDNSLKIVSN.A phosphate 147] dehydrogenase VN, VS, YD [437- EP, TA, VR, AV, 68 65 Titin VR, VE, AV, RVR - - A.RVREPVISAVEQTAQR.T 452] PV, QT, VE, VI

VA, SL, DP, HY, [1104- 69 Nebulin HY, KL, LQ LV, MN, NV, PK, LV - 1119] Q.SLQDDPKLVHYMNVAK.I QD, VH, YM

VAA, AA, GK, QG, VA, KA(2), VR, Phosphoglycerate [235- 70 EA, VR, KA(2), ME, AA, AV, ET, ME, EE - 66 mutase 253] G.DEETVRKAMEAVAAQGKAK.- AV QG, RK, TV

KA, FA, AL, AG, [411- VF, AG, GR, LG, GD, 71 Beta-elonase AV, KF, MR, RI, EE - 67 428] EA, KF, KA, IE, AV L.MRIEEALGDKAVFAGRKF.R RK, VF

VA, SL, DP, FQ, [1102- HY, LV, MN, NV, 72 Nebulin HY, KL, LQ, FQ LV - 1119] PK, QD, QS, VH, G.FQSLQDDPKLVHYMNVAK.I YM

KA, VP, VV, EK, [509- IR, VPK, AF, VP, KA, AF, ET, HE, IR, KE, 73 Titin - FVP 527] TE, EK, KE KV, PK, QI, RK, S.HEQIRKETEKAFVPKVVIS.A68 TE, VI

GA(2), FG, DA, QG, KA, HP, GA(2), AL, [117- 74 L.ESKHPGDFGADAQGAMSKALEL.F69 Myoglobin GD, PG, KA, HP, DF, AD, ES, KH, PG, - EL 137] DFG QG, SK(2) VP, KP, NP, SL, GKP, VP, AA, DA, Elongation factor 1- [389- AA, DN, KS(2), 75 E.DNPKSLKSGDAAIVEMVPGKPM.C70 GK, SG, GD, PG, KP, IV LK, KP alpha 2 910] MV, PG, PK, PM, VE, AI VE

SP(2), FP, RA, PL, VF, VY, FP, PR, PL, G.SPLSSPVFPRAGFGTKGSSSSVTSRVYQ. AG, GF, KG, PV, 76 Desmin [28-55] RA, GF, AG, KG, FG, SSS(2) VY V71 SV, TK, TS, VF, GS, GT, RVY VT, VY, YQ

GP, PA, LP, IP, KP, 7 GPA, AKK, LPG, GP, D.DEEKKPIPGAKKLPGPAVNLSEIQNIK.S Small muscular GPA, GA, EK, AV, 77 [49-75] IP, GA, PG, KL, KP, EE, SE KP 2 protein EI, IQ, KK(2), NL, EI, EK, AV PG(2), PI, QN, VN

FA, AP, VP, VV, FAP, LRP, VK, RP, RP, ET, EV, GI, IL, AP, VP, VG, GI, GM, Elongation factor 1- [261- KS, MV, PG, PV(2), 78 GR, TG, PG, ITT, EV, IL - alpha 2 292] TE, TF, TG, TT, VE, TE, TF, GILRP, G.TVPVGRVETGILRPGMVVTFAPVNITTE TV, VE, VG, VK, 73 IL, LR VKS.V VN, VT

VF, FP(2), PR, PLG, AP, SP(2), FP(2), PL(2), AP, RA, GF, GA, RA, PL(2), AG, 79 Desmin [13-44] GA, AG, KG, FG(2), GF, GG, KG, PS, - - S.SYRRTFGGAPSFPLGSPLSSPVFPRAGFG GS, GT, GG, LG, SY, PV, RR, SF, SY, TF, TKG.S74 SF, RR, TF TK, VF, YR

PDZ and LIM [181- HA, GV, KI, PG, 80 75 VK, GV, PG IV - L.PGVKIVHA.Q domain protein 3 188] VH, VK

Actin, alpha skeletal [363- GP, AG, PS, SI, VH, 81 76 GP, AG, EA, AGP IV - E.YDEAGPSIVH.R muscle 373] YD

[244- LVL, GPL, LGP, GP, GP, LL, EP, PL(2), VL, LV, LL, 82 77 - F.DLGPLLSEPLVL.V Myozenin-1 255] PL(2), LG, DLGP LV, VL SE

Troponin I, fast [152- 83 78 VG, GD, LR WRK, WR, RK, VG - - K.ERDLRDVGDWRK.N skeletal muscle 163] [6196- DLP, VK(2), KR, QK, LP, ET, EV, KE, 84 79 Nebulin - - I.PDLPEVKRVKETQKH.I 6210] EV, TQ, KE KH, KR, TQ, VK(2)

DA, EA, NK, KP, IE, KP, EK, KE, PF, 85 80 Myosin-8 [22-37] SE KP K.SEKERIEAQNKPFDAK.T EK, KE QN, RI

KR, VG, GI, GQ, GD, GI, IL, KR, LT, QS, 86 EA, QK, SY, YV, IL, RG, SK, SY, VG, IL KD, YVGD GQKDSYVGDEAQSKRGILT81 RG YV

LIM domain-binding [255- EA, RR, AR, KP, LQ, KP, WA, AD, EW, 87 82 - KP N.KPEDEADEWARRSSNLQS.R protein 3 272] EW, WA NL, QS, RR

LIM domain-binding [254- EA, NK, RR, AR, KP, KP, WA, AD, EW, 88 83 - KP Q.NKPEDEADEWARRSSNLQ.S protein 3 271] LQ, EW, WA NL, RR

Troponin I, fast [159- GM, GR, SG, GD, EG, EK, WRK, WR, EG, 89 84 EE - V.GDWRKNIEEKSGMEGRKK.M skeletal muscle 176] IE, ME, EK KK, KS, ME, RK(2)

LIM domain-binding [254- EA, NK, RR, AR, KP, KP, WA, AD, EW, 90 85 - KP Q.NKPEDEADEWARRSSNLQSR.S protein 3 273] LQ, EW, WA NL,QS, RR

VF, FR, AG, GR, LG, KA(2), FA, NP, AL, [412- 91 Beta-elonase GD, EA, KF, KA(2), AG, AV, FR, KF, EE - 86 434] M.RIEEALGDKAVFAGRKFRNPKAK.- IE, AV PK, RI, RK, RN, VF

TP, IA, RA, AS, AT, [6028- IA, RA, KY, YK, AR, ET, KY, MR, NA, 92 Nebulin - - M.ANETPDFMRARNATDIASQIKYKQ.S + 6051] IKY, TP, DF NE, QI, RN, TD, Oxidation (M)87 YK

LIM domain-binding LP, IP, SP, PL, PH, 93 [98-105] PLP, PL, IP, PH - - Q.SPLPVIPH.Q protein 3 PV, VI

1 sign (.) indicate cutting points 2 position in parental protein 3 Stimulating vasoactive substance release or glucose uptake stimulating peptide 4other activity: dipeptidyl peptidase III inhibitor- PE; alpha-glucosidase inhibitor – EA 5 the number in () indicates the number of identified peptides, if more than one 6other activity: dipeptidyl peptidase III inhibitor - LP, antiamnestic (PEP inhibitor - LPPV, Prolyl endopeptidase inhibitor –PG; antithrombotic and peptide regulating the stomach mucosal membrane activity - PG; alpha-glucosidase inhibitor - PP; renin inhibitor – LR 7 other activity: dipeptidyl peptidase III inhibitor - FA; bacterial permease ligand – KK; hypolipidemic - EF; alpha-glucosidase inhibitor- PP; CaMPDE inhibitor and renin inhibitor – EF 8 other activity: dipeptidyl peptidase III inhibitor- LR; antiamnestic (PEP inhibitor – LPPV, Prolyl endopeptidase inhibitor – PG; antithrombotic, peptide regulating the stomach mucosal membrane activity - PG; alpha-glucosidase inhibitor - PP; renin inhibitor - LR 9 other activity: dipeptidyl carboxypeptidase inhibitor – PPPA; alpha-glucosidase inhibitor - PP(2) 10 other activity: rennin inhibitor – SF; 11 other activity: dipeptidyl peptidase III inhibitor – YK 12 other activity: antiamnestic ( prolyl endopeptidase inhibitor), antithrombotic and regulating– GP; CaMPDE inhibitor and renin inhibitor – KF 13 other activity: dipeptidyl peptidase III inhibitor - KA; antiamnestic ( prolyl endopeptidase inhibitor), antithrombotic and regulating– GP 14 other activity: dipeptidyl peptidase III inhibitor- PE 15 other activity: dipeptidyl peptidase III inhibitor- YK 16 other activity: dipeptidyl peptidase III inhibitor- YK, DA(2) 17 other activity: dipeptidyl carboxypeptidase inhibitor - PPPA, alpha-glucosidase inhibitor – PP(3) 18 other activity: dipeptidyl peptidase III inhibitor- KA, CaMPDE inhibitor and renin inhibitor – IR 19 other activity: dipeptidyl peptidase III inhibitor-TF, DA, HF, renin inhibitor – TF 20 other activity: dipeptidyl peptidase III inhibitor - YK, DA(2), KA 21 other activity: dipeptidyl peptidase III inhibitor – IH, PE 22 other activity: dipeptidyl peptidase III inhibitor and activating ubiquitin-mediated proteolysis – LA 23 other activity: dipeptidyl peptidase III inhibitor – KA; antiamnestic (prolyl endopeptidase inhibitor ), antithrombotic and peptide regulating the stomach mucosal membrane activity – GP 24 other activity: dipeptidyl peptidase III inhibitor and activating ubiquitin-mediated proteolysis – LA; bacterial permease ligand – KK; alpha-glucosidase inhibitor – EA 25 other activity: alpha-glucosidase inhibitor – EA, PP(3); dipeptidyl carboxypeptidase inhibitor – PPPA 26 other activity: dipeptidyl peptidase III inhibitor – RV 27 other activity: dipeptidyl peptidase III inhibitor – KA; bacterial permease ligand – KK 28 other activity: dipeptidyl peptidase III inhibitor – GE; alpha-glucosidase inhibitor – EA 29 other activity: dipeptidyl peptidase III inhibitor – GF, PR; activating ubiquitin-mediated proteolysis – RA 30 other activity: dipeptidyl peptidase III inhibitor - HP, PE; alpha-glucosidase inhibitor – EA 31 other activity: dipeptidyl peptidase III inhibitor – TF, DA, HF; renin inhibitor – TF 32 other activity: antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and regulating the stomach mucosal membrane activity – GP; alpha-glucosidase inhibitor - EA 33 other activity: antiamnestic (prolyl endopeptidase inhibitor) , antitrombotic and peptide regulating the stomach mucosal membrane activity - PG 34 other activity: dipeptidyl peptidase III inhibitor – IH, PE; renin inhibitor – FT 35 other activity: dipeptidyl peptidase III inhibitor – GE, alpha-glucosidase inhibitor - EA 36 other activity: dipeptidyl peptidase III inhibitor - YK 37 other activity: bacterial permease ligand - KK 38 other activity: dipeptidyl peptidase III inhibitor – KA, CaMPDE inhibitor nad renin inhibitor – IR 39 other activity: dipeptidyl peptidase III inhibitor – RV, HP, PE; alpha-glucosidase inhibitor - EA 40 other activity: dipeptidyl peptidase III inhibitor – LR, YK, KA; bacterial permease ligand – KK 41 other activity: dipeptidyl peptidase III inhibitor – RV, KA; bacterial permease ligand – KK; alpha-glucosidase inhibitor - EA 42 other activity: antiamnestic (prolyl endopeptidase inhibitor) , antitrombotic and peptide regulating the stomach mucosal membrane activity - GP 43 other activity: dipeptidyl peptidase III inhibitor and neuropeptide (Kyotorphin ) – YR; peptide regulating ion flow - DY 44 other activity: dipeptidyl peptidase III inhibitor and neuropeptide (Kyotorphin) - YR; peptide regulating ion flow - DY 45 other activity: dipeptidyl peptidase III inhibitor – KA; bacterial permease ligand – KK 46 other activity: dipeptidyl peptidase III inhibitor – GF, PR; activating ubiquitin-mediated proteolysis - RA; opioid(gliadin 1 exorphin ) – PLG; renin inhibitor – SF; 47 other activity: dipeptidyl peptidase III inhibitor – LR, DA, HP; renin inhibitor – LR 48 other activity: dipeptidyl peptidase III inhibitor - PR; antithrombotic - PPK; dipeptidyl carboxypeptidase inhibitor – PPPA, PPAP; alpha-glucosidase inhibitor - PP(6) 49 other activity: dipeptidyl peptidase III inhibitor – RF, FL, KA(2); antithrombotic - DEE; alpha-glucosidase inhibitor - EA 50 other activity: dipeptidyl peptidase III inhibitor – GF, PR, RV, VY; activating ubiquitin-mediated proteolysis – RA 51 other activity: dipeptidyl peptidase III inhibitor – IH, PE, KA; renin inhibitor – FT 52 other activity: dipeptidyl peptidase III inhibitor – PF; alpha-glucosidase inhibitor – PP(2) 53 other activity: dipeptidyl peptidase III inhibitor – RR, GE; alpha-glucosidase inhibitor – EA 54 other activity: dipeptidyl peptidase III inhibitor – RV; CaMPDE inhibitor and hypolipidemic – EF; renin inhibitor – EF, NR 55 other activity: dipeptidyl peptidase III inhibitor – GE, RV 56 other activity: dipeptidyl peptidase III inhibitor – GE, RV; renin inhibitor – LY; peptide regulating the stomach mucosal membrane activity - PG 57 other activity: dipeptidyl peptidase III inhibitor – LR, RR, RV, PE; renin inhibitor – LR, LY; bacterial permease ligand – KK; alpha-glucosidase inhibitor - YP, YPY, EA 58 other activity; renin inhibitor – YA 59 other activity: dipeptidyl peptidase III inhibitor – HF 60 other activity; renin inhibitor – YA 61 other activity: dipeptidyl peptidase III inhibitor – HL, KA 62 other activity: dipeptidyl peptidase III inhibitor – DA, KA 63 other activity: dipeptidyl peptidase III inhibitor – YK 64 other activity: dipeptidyl peptidase III inhibitor – GF, PR; activating ubiquitin-mediated proteolysis - RA 65 other activity: dipeptidyl peptidase III inhibitor – RV 66 other activity: dipeptidyl peptidase III inhibitor – KA(2), antithrombotic - DEE, alpha-glucosidase inhibitor - EA 67 other activity: dipeptidyl peptidase III inhibitor – KA, MR, FA; CaMPDE inhibitor and renin inhibitor – KF; alpha-glucosidase inhibitor - EA 68 other activity: dipeptidyl peptidase III inhibitor – KA; CaMPDE inhibitor and renin inhibitor – IR 69 other activity: dipeptidyl peptidase III inhibitor – DA, HP, KA; antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – PG 70 other activity: dipeptidyl peptidase III inhibitor – DA; antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – PG 71 other activity: dipeptidyl peptidase III inhibitor – GF, PR, RV, VY; activating ubiquitin-mediated proteolysis - RA 72 other activity: antiamnestic (prolyl endopeptidase inhibitor ) – PGP, PG(2), GP; antithrombotic – GP, PGP, PG(2), DEE; peptide regulating the stomach mucosal membrane activity – GP, PG(2), PGP; bacterial permease ligand – KK; inhibitor of insulin secretion and chemotactic – PGP; 73 other activity: dipeptidyl peptidase III inhibitor – LR, TF, RV, FA; antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – PG; renin inhibitor - LR, TF 74 other activity: dipeptidyl peptidase III inhibitor – YR, RR, TF, GF, PR; activating ubiquitin-mediated proteolysis - RA, opioid (gliadin 1 exorphin) – PLG; neuropeptide (Kyotorphin) – YR; renin inhibitor – SF, TF 75 other activity: antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – GP 76 other activity: antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – GP 77 other activity: antiamnestic (prolyl endopeptidase inhibitor), antithrombotic and peptide regulating the stomach mucosal membrane activity – GP 78 other activity: dipeptidyl peptidase III inhibitor and renin inhibitor – LR 79 other activity: dipeptidyl peptidase III inhibitor and renin inhibitor – RV, PE 80 other activity: dipeptidyl peptidase III inhibitor and renin inhibitor – DA, PF; alpha-glucosidase inhibitor - EA 81 other activity: neuropeptide - GQ; alpha-glucosidase inhibitor - EA 82 other activity: dipeptidyl peptidase III inhibitor – RR, PE; peptide activating ubiquitin-mediated proteolysis – WA; alpha-glucosidase inhibitor - EA 83 other activity: dipeptidyl peptidase III inhibitor – RR, PE; activating ubiquitin-mediated proteolysis - WA, alpha-glucosidase inhibitor - EA 84 other activity: bacterial permease ligand – KK 85 other activity: dipeptidyl peptidase III inhibitor – RR, PE; activating ubiquitin-mediated proteolysis – WA; alpha-glucosidase inhibitor – EA 86 other activity: dipeptidyl peptidase III inhibitor – FA, FR, KA(2); CaMPDE inhibitor and renin inhibitor – KF; alpha-glucosidase inhibitor - EA

Table 3. List of peptide sequences common for conventional and organic shoulders

Antioxidan Sequence1 Protein Position2 ACE inhibitor DPP-IV inhibitor Stimulating3 t

PDZ and LIM [177- LPG, VK, GV, LP, HA, GV, KI, ME, 1 L.EMELPGVKIVHA.Q4 IV EL domain protein 188] PG, ME PG, VH, VK

[438- EP, TA, VR, AV, PV, 2 R.VREPVISAVEQTAQR.T Titin VR, VE, AV - - 452] QT, VE, VI

AY, AA, DA(2)5, [5525- KA, EP, AA, AV, AY, 3 T.IEPDAVHIKAAKDAYK.V6 Neulin YK, KA, IE, IEP, - AY, KD 5540] HI, VH, YK AV

PPPP, PP(3), AP, PA, Troponin T, fast AP, EV(3), 4 E.APPPPAEVHEVHEEVH.E7 [23-38] AE, EV(3), HE(2), EE - skeletal muscle PP(3), PPP(2) VH(3)

AP, EA, EV(3), PPPP, PP(3), AP, PA, Troponin T, fast 5 E.EAPPPPAEVHEVHEEVH.E8 [22-38] PP(3), EAP, AE, EV(3), HE(2), EE - skeletal muscle PPP(2) VH(3)

[153- KA, HA, EH, KK, KV, 6 E.KAKDIEHAKKVSQQVSK.V9 Nebulin AKK, KA, IE - KD 169] QQ, QV, SK, VS(2)

[451- GE, EA, DG, IE, VV, AT, ET, EV, GE, 7 T.IETRDGEVVSEATQQQH.E10 Desmin SE - 467] EV, TQ QH, QQ(2), TQ, TR, VS

VAP, LNP, PL, VA, AP(2), LL, HP, NP, Actin, aortic 8 R.VAPEEHPTLLTEAPLNPK.A11 [97-115] AP(2), EA, TE, PL, EH, LN, LT, PK, PT, LL, EE - smooth muscle LN, PT, HP, EAP TE, TL

GP, AG, EY, HR, PS, Actin, alpha [359- GP, AG, EA, EY, 9 W.ITKQEYDEAGPSIVHRK.C12 QE, RK, SI, TK, VH, IV - skeletal muscle 375] AGP YD

GP, WI, AG, EY, HR, Actin, alpha [358- GP, AG, EA, EY, 10 M.WITKQEYDEAGPSIVHRK.C13 PS, QE, RK, SI, TK, VH, IV - skeletal muscle 375] AGP YD

Troponin I, MF, AA, GM, [165- SP, AA, EG, KK, KS, 11 A.MSGMEGRKKMFDAAKSPTSQ.-14 slow skeletal GR, DA, SG, EG, - - 184] ME, MF, PTM RK, TS muscle PT, ME

RF, VAA, AA, VA, KA(2), KL, VR, Phosphoglycera [231- GK, QG, LG, 12 M.RFLGDEETVRKAMEAVAAQGKAK.-15 AA, AV, ET, ME, QG, EE - te mutase 2 253] GD, EA, VR, RK, TV KA(2), ME, AV

VA, KA, RP, AA, YT, [5736- 13 H.YTTVADRPDIKKATQAAKQ.A16 Nebulin RP, AA, KA, TQ AD, AT, DR, KK, QA, - IKK 5754] TQ, TT, TV

GP, LA, VG, EA, GP, VA, KA, LA, AD, ATP synthase [509- 14 Y.MVGPIEEAVAKADKLAEEHS.-17 KL, KA, IE, AV, AE, AV, EH, HS, MV, EE(2) - subunit beta 528] VGP PI, VG

VG, GM, GR, Troponin T, fast [157- EK, WRK, WR, EG, 15 R.DVGDWRKNIEEKSGMEGRKK.M18 SG, DG, EG, IE, EE - skeletal muscle 176] KK, KS, ME, RK(2), VG ME, EK

1 sign (.) indicate cutting points 2 position in parental protein 3 stimulating vasoactive substance release or glucose uptake stimulating peptide 4 other activity: antiamnestic, antitrombotic, regulating the stomach mucosal membrane activity - PG 5 the number in () indicates the number of identified peptides, if more than one 6 other activity: dipeptidyl peptidase III inhibitor – YK, DA(2), KA 7 other activity: dipeptidyl carboxypeptidase inhibitor – PPPA; alpha-glucosidase inhibitor – PP(3) 8 other activity: dipeptidyl carboxypeptidase inhibitor – PPPA; alpha-glucosidase inhibitor – PP(3) 9 other activity: dipeptidyl peptidase III inhibitor – KA; bacterial permease ligand - KK 10 other activity: dipeptidyl peptidase III inhibitor – GE; alpha-glucosidase inhibitor – EA 11 other activity: dipeptidyl peptidase III inhibitor – HP, PE; alpha-glucosidase inhibitor – EA 12 other activity: antiamnestic, antitrombotic, regulating the stomach mucosal membrane activity – GP; alpha-glucosidase inhibitor – EA 13 other activity: antiamnestic, antitrombotic, regulating the stomach mucosal membrane activity – GP; alpha-glucosidase inhibitor – EA 14 other activity: dipeptidyl peptidase III inhibitor – DA; bacterial permease ligand – KK 15 other activity: dipeptidyl peptidase III inhibitor – RF, FL, KA(2); antithrombotic - DEE 16 other activity: dipeptidyl peptidase III inhibitor – KA; bacterial permease ligand - KK 17 other activity: dipeptidyl peptidase III inhibitor – LA, KA; antiamnestic, antitrombotic, regulating the stomach mucosal membrane activity – GP; activating ubiquitin- mediated proteolysis - LA 18 other activity: bacterial permease ligand - KK