Florida International University FIU Digital Commons All Faculty 5-29-2009 How do psychiatric drugs work? Joanna Moncrieff David Cohen School of Social Work, Florida International University,
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[email protected]. ANALYSIS How do psychiatric drugs work? Joanna Moncrieff and David Cohen argue that changing our view of the action of psychiatric drugs would help patients to become more involved with decisions about treatment Drugs for psychiatric problems are pre- a neurological syndrome consisting of physi- and altered sense perception, could have an scribed on the assumption that they mostly cal restriction and mental symptoms such effect on the symptoms of distress in countless act against neurochemical substrates of dis- as cognitive slowing, apathy, and emotional disorders and be distinguished from effects orders or symptoms. In this article we ques- flattening, which resembled Parkinson’s dis- associated with inert placebo.6 Any drug with tion that assumption, proposing that drugs’ ease.2 These effects also reduced the intensity sedative properties, for example, will modify action be viewed rather as producing altered, of psychotic symptoms. Thus, extrapyramidal disturbances of sleep and arousal found in drug induced states, a view we have called effects, and their con- many psychiatric the drug centred model of action. We believe joined mental effects, conditions and in that this view accords better with the avail- were not regarded the disorder specific able evidence.