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Symposium Program Book 13th ANNUAL NIH GRADUATE STUDENT RESEARCH SYMPOSIUM THE FACES OF TOMORROW'S SCIENCE FEBRUARY 23, 2017 NIH NATCHER CONFERENCE CENTER, BETHESDA, MARYLAND 13th ANNUAL NIH GRADUATE STUDENT RESEARCH SYMPOSIUM THE FACES OF TOMORROW'S SCIENCE 2017 FOREWORD AND ACKNOWLEDGEMENTS .................. 2 PROGRAM OF EVENTS ................................................ 4 NIH GRADUATE PARTNERSHIPS PROGRAM GRADUATION AWARD RECIPIENTS ............................ 5 KEYNOTE SPEAKER .................................................... 8 STUDENT SPEAKERS .................................................. 9 OUTSTANDING MENTOR AWARD RECIPIENTS ..........11 STUDENTS ..................................................................12 POSTERS ....................................................................17 Graduate Partnerships Program Office of Intramural Training & Education Office of Intramural Research National Institutes of Health U.S. Department of Health & Human Services 1 FOREWORD very year, the National Institutes of Health (NIH) Graduate Student Research Symposium showcases the Ebreadth of scientific research and the achievements of the graduate student community at the NIH. The symposium is the largest graduate student event of the year, an event in which graduate students can come together to share their research, appreciate the work of their colleagues, and celebrate the successes of the graduate student community. In its thirteenth year, this annual symposium provides an opportunity to acknowledge the scientific accomplishments of the hundreds of graduate students working on their dissertation research at the NIH. This symposium highlights the spectrum of scientific research conducted by graduate students at the NIH, who represent numerous universities across the world and span nearly all institutes and centers within the NIH. The NIH Graduate Research Symposium recognizes the diversity of research specialties supported by the NIH and exhibits the scientists of tomorrow, from those developing new research proposals to those preparing to defend years of dissertation research. This symposium will provide the graduate student community with the chance to hear about the scientific work of our peers in several formats. In the morning, we will be holding our inaugural elevator pitch competition in which current graduate students will be judged on their ability to explain their science to a general audience in two minutes or less. Dr. Sharon Milgram, Director of the Office of Intramural Training and Education (OITE), will deliver welcoming remarks, followed by four current students, who will present scientific talks chosen based on scientific merit and diversity. In the afternoon, students will present their research through scientific posters judged by NIH postdoctoral fellows and staff scientists. Winners of the poster competition will be awarded the prestigious NIH Graduate Student Research Award generously funded by the OITE. Following the poster session, we are honored to welcome our keynote speaker, Dr. Rajendrani Mukhopadhyay, managing editor at American Society for Biochemistry and Molecular Biology (ASBMB) Today. Dr. Mukhopadhyay pursued a PhD in biophysics and biochemistry in the laboratory of Dr. Jan Hoh at Johns Hopkins University. After struggling with the lack of instant gratification in science, Dr. Mukhopadhyay realized she loved the challenge of graduate school and the success of finishing. She pursued a former passion of hers after graduating and started her science-writing career at the American Chemical Society. Dr. Mukhopadhyay then joined ASBMB, writing feature stories and scientist profiles for ASBMB Today and the Wild Types blog and later becoming senior editor of ASBMB Today. She used knowledge gained from her PhD training to develop a strong sense of curiosity, the ability to ask the right questions, and the ability to frame all the information into a story—qualities necessary for a writing career and that will help us as graduate students develop a scientific project. Today, Dr. Mukhopadhyay will present how storytelling can make you a better scientist. Her story and advice will be valuable for NIH graduate students in addressing how graduate school can be an opportunity for personal growth and how graduate students can find their dream career path. 2 NIH GRADUATE STUDENT RESEARCH SYMPOSIUM 2017 Following our keynote address, we will present the awards for outstanding research mentors. Our success as graduate students would not be the same without the guidance of high-quality research mentors, who support us in innumerable ways, from providing networking opportunities to career development advice. We are grateful for the influential mentorship provided at the NIH to help us become independent scientists and forge relationships extending beyond graduate school. Three outstanding mentors nominated by their students will be honored for their leadership, support, and dedication to their graduate students. Afterwards, we will conclude the day with a graduation ceremony to recognize those students who have defended their dissertations within the past year. Dr. Sharon Milgram will present the recent graduates with a certificate in honor of their accomplishments. We are thankful for the opportunity to share our research with the entire NIH community at the 13th Annual NIH Graduate Student Research Symposium. We thank all of the graduate students who participated in this event and those who have provided us with continuous support in our scientific careers. We hope this event establishes new connections and collaborations, and inspires future scientific contributions to the community at the NIH. ACKNOWLEDGEMENTS We are grateful to the Training and Scientific Directors of the NIH Institutes and Centers, the Graduate Partnerships Program (GPP) Directors, and the Graduate Student Council (GSC) for their continuous support of the graduate student community and for the opportunity to recognize the achievements of the NIH graduate students at this symposium. We would like to thank Dr. Gail Seabold and Dr. Courtney Kurtyka for organizing the symposium poster session, and we acknowledge the effort of the postdoctoral fellow and staff scientist judges for helping to make the poster competition possible. We would like to thank the 2016 GSC co-chairs, Kara Fulton and Kimberly Breglio, for managing the Outstanding Mentor Awards and for all of their efforts and dedication to the GSC and graduate student community. This symposium would not be possible without the help of the Office of Intramural Training and Education (OITE). We are especially thankful for Dr. Sharon Milgram, Dr. Philip Wang, Dr. Phil Ryan and other OITE staff who have contributed significantly to the planning of this event. We would like to extend a big thank you to Dr. Rajendrani Mukhopadhyay for her enthusiasm and willingness to deliver our keynote address. Finally, we would like to thank the graduate students, mentors, alumni, and all attendees whose participation made this event successful. THE 13TH ANNUAL NIH GRADUATE RESEARCH SYMPOSIUM COMMITTEE Kimberly Breglio, NIAID/University of Oxford Leda Lotspeich-Cole, NICHD/Johns Hopkins University Carly Starke, NIAID/Georgetown University Keyla Tumas, NIAID/Georgetown University 3 PROGRAM OF EVENTS 9:00 am-10:00 am ELEVATOR PITCH COMPETITION Lower Lobby 10:00 am-10:15 am WELCOME Room E1/E2 Sharon L. Milgram, PhD Director, NIH Office of Intramural Training & Education (OITE) 10:15 am-11:45 am STUDENT ORAL PRESENTATIONS Room E1/E2 Lydia Louis, Rutgers, The State University of New Jersey, NCI-DCEG Personal Use of Organochlorine Insecticides and Cancer Risks Among the Agricultural Health Study Farm Spouses Nityashree Shivaprasad, Georgetown University, NCI FGFR4 specific Chimeric Antigen Receptor (CAR) T Cell Therapy Against Rhabdomyosarcoma Rodrigo Matus Nicodemos, Johns Hopkins Univeristy, NIAID HLA-A and HLA-B Down Modulation in HIV-Infected Cells Occurs Late in the Viral Replicative Cycle Christie Campla, University of Oxford, NEI Frmpd1: A Novel Gene Involved in Rod Photoreceptor Maturation 11:45 am-12:45 pm POSTER SESSION I Atrium Odd numbered posters presenting 12:45 pm-1:45 pm POSTER SESSION II Atrium Even numbered posters presenting 2:00 pm-3:00 pm KEYNOTE ADDRESS Ruth L. Kirschstein Rajendrani Mukhopadhyay, PhD Auditorium Managing Editor, ASBMB Today 3:00 pm-4:00 pm AWARDS CEREMONY Ruth L. Kirschstein Graduation Ceremony Auditorium Certificates presented by: Sharon L. Milgram, PhD, Director, NIH Office of Intramural Training & Education Outstanding Mentor Awards Daniel Reich MD, PhD John Kehrl, MD Jeffrey C. Smith, PhD NIH Graduate Student Research Awards (NGSRAs) 4 NIH GRADUATE STUDENT RESEARCH SYMPOSIUM 2017 GPP GRADUATION AWARD RECIPIENTS GPP GRADUATION AWARD RECIPIENT, NIH IC, UNIVERSITY, DISSERTATION TITLE MENTOR UNIVERSITY MENTOR Fereshteh Aalamifar CC Johns Hopkins University Co-robotic Ultrasound Tomography: A New Paradigm for Dr. Bradford Wood Dr. Emad M. Boctor Quantitative Ultrasound Imaging Dr. Peter Pinto Dr. Arman Rahmim Defne Bayik NCI Ihsan Dogramaci Bilkent Regulation of Human Monocyte Differentiation into M1- and Dr. Dennis M. Klinman University M2-like Macrophages Shaunna Beedie NCI University of Aberdeen An Investigation of Thalidomide Derivatives for Clinical Use Dr. William Douglas Figg Dr. Neil Vargesson Pascale Beliveau NHLBI Ecole Polytechnique Texture Analysis of Late Gadolinium Enhanced Cardiac Dr. Li-Yueh Hsu of Montreal Magnetic Resonance Images for Characterizing Myocardial
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