Anti-TGFBRAP1 Monoclonal Antibody (DCABH- 201577) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-TGFBRAP1 monoclonal antibody (DCABH- 201577) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description TGFBRAP1 (transforming growth factor, beta receptor associated protein 1) is a protein-coding gene. Diseases associated with TGFBRAP1 include t cell deficiency, and hepatitis c. GO annotations related to this gene include transforming growth factor beta receptor binding and SMAD binding. An important paralog of this gene is VPS39. Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor- regulated Smads, such as SMAD2.

Immunogen A synthetic peptide of human TGFBRAP1 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications WB, ELISA

Size 1 mg

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name TGFBRAP1 transforming growth factor, beta receptor associated protein 1 [ Homo sapiens (human) ]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Synonyms TGFBRAP1; transforming growth factor, beta receptor associated protein 1; TRAP1; TRAP-1; transforming growth factor-beta receptor-associated protein 1; TGF-beta receptor-associated protein 1; TGF beta receptor associated protein -1;

Entrez Gene ID 9392

Protein Refseq NP_001136093

UniProt ID Q8WUH2

Chromosome Location 2q12.1

Function SMAD binding; protein binding; small GTPase regulator activity; transforming growth factor beta receptor binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]