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Entry and Early Infection of Non-Segmented Negative Sense Rna Viruses
University of Kentucky UKnowledge Theses and Dissertations--Molecular and Cellular Biochemistry Molecular and Cellular Biochemistry 2021 ENTRY AND EARLY INFECTION OF NON-SEGMENTED NEGATIVE SENSE RNA VIRUSES Jean Mawuena Branttie University of Kentucky, [email protected] Digital Object Identifier: https://doi.org/10.13023/etd.2021.248 Right click to open a feedback form in a new tab to let us know how this document benefits ou.y Recommended Citation Branttie, Jean Mawuena, "ENTRY AND EARLY INFECTION OF NON-SEGMENTED NEGATIVE SENSE RNA VIRUSES" (2021). Theses and Dissertations--Molecular and Cellular Biochemistry. 54. https://uknowledge.uky.edu/biochem_etds/54 This Doctoral Dissertation is brought to you for free and open access by the Molecular and Cellular Biochemistry at UKnowledge. It has been accepted for inclusion in Theses and Dissertations--Molecular and Cellular Biochemistry by an authorized administrator of UKnowledge. For more information, please contact [email protected]. STUDENT AGREEMENT: I represent that my thesis or dissertation and abstract are my original work. Proper attribution has been given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained needed written permission statement(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic distribution (if such use is not permitted by the fair use doctrine) which will be submitted to UKnowledge as Additional File. I hereby grant to The University of Kentucky and its agents the irrevocable, non-exclusive, and royalty-free license to archive and make accessible my work in whole or in part in all forms of media, now or hereafter known. -
2020 Taxonomic Update for Phylum Negarnaviricota (Riboviria: Orthornavirae), Including the Large Orders Bunyavirales and Mononegavirales
Archives of Virology https://doi.org/10.1007/s00705-020-04731-2 VIROLOGY DIVISION NEWS 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales Jens H. Kuhn1 · Scott Adkins2 · Daniela Alioto3 · Sergey V. Alkhovsky4 · Gaya K. Amarasinghe5 · Simon J. Anthony6,7 · Tatjana Avšič‑Županc8 · María A. Ayllón9,10 · Justin Bahl11 · Anne Balkema‑Buschmann12 · Matthew J. Ballinger13 · Tomáš Bartonička14 · Christopher Basler15 · Sina Bavari16 · Martin Beer17 · Dennis A. Bente18 · Éric Bergeron19 · Brian H. Bird20 · Carol Blair21 · Kim R. Blasdell22 · Steven B. Bradfute23 · Rachel Breyta24 · Thomas Briese25 · Paul A. Brown26 · Ursula J. Buchholz27 · Michael J. Buchmeier28 · Alexander Bukreyev18,29 · Felicity Burt30 · Nihal Buzkan31 · Charles H. Calisher32 · Mengji Cao33,34 · Inmaculada Casas35 · John Chamberlain36 · Kartik Chandran37 · Rémi N. Charrel38 · Biao Chen39 · Michela Chiumenti40 · Il‑Ryong Choi41 · J. Christopher S. Clegg42 · Ian Crozier43 · John V. da Graça44 · Elena Dal Bó45 · Alberto M. R. Dávila46 · Juan Carlos de la Torre47 · Xavier de Lamballerie38 · Rik L. de Swart48 · Patrick L. Di Bello49 · Nicholas Di Paola50 · Francesco Di Serio40 · Ralf G. Dietzgen51 · Michele Digiaro52 · Valerian V. Dolja53 · Olga Dolnik54 · Michael A. Drebot55 · Jan Felix Drexler56 · Ralf Dürrwald57 · Lucie Dufkova58 · William G. Dundon59 · W. Paul Duprex60 · John M. Dye50 · Andrew J. Easton61 · Hideki Ebihara62 · Toufc Elbeaino63 · Koray Ergünay64 · Jorlan Fernandes195 · Anthony R. Fooks65 · Pierre B. H. Formenty66 · Leonie F. Forth17 · Ron A. M. Fouchier48 · Juliana Freitas‑Astúa67 · Selma Gago‑Zachert68,69 · George Fú Gāo70 · María Laura García71 · Adolfo García‑Sastre72 · Aura R. Garrison50 · Aiah Gbakima73 · Tracey Goldstein74 · Jean‑Paul J. Gonzalez75,76 · Anthony Grifths77 · Martin H. Groschup12 · Stephan Günther78 · Alexandro Guterres195 · Roy A. -
Konzept Für Lokalfauna
ZOBODAT - www.zobodat.at Zoologisch-Botanische Datenbank/Zoological-Botanical Database Digitale Literatur/Digital Literature Zeitschrift/Journal: Mitteilungen der Entomologischen Arbeitsgemeinschaft Salzkammergut Jahr/Year: 2004 Band/Volume: 2004 Autor(en)/Author(s): Kallies Axel, Pühringer Franz Artikel/Article: Provisional checklist of the Sesiidae of the world (Lepidoptera: Ditrysia) 1-85 ©Salzkammergut Entomologenrunde; download unter www.biologiezentrum.at Mitt.Ent.Arb.gem.Salzkammergut 4 1-85 4.12.2004 Provisional checklist of the Sesiidae of the world (Lepidoptera: Ditrysia) Franz PÜHRINGER & Axel KALLIES Abstract: A checklist of Sesiidae of the world provides 2453 names, 1562 of which are currently considered valid taxa (1 family, 2 subfamilies, 10 tribes, 149 genera, 1352 species, and 48 subspecies). Data concerning distribution, type species or type genus, designation, incorrect spelling and emendation, preoccupation and replacement names, synonyms and homonyms, nomina nuda, and rejected names are given. Several new combinations and synonyms are provided. Key words: Sesioidea, systematics, taxonomy, zoogeographic regions. Introduction: Almost 25 years have passed since HEPPNER & DUCKWORTH (1981) published their 'Classification of the Superfamily Sesioidea'. In the meantime great progress has been made in the investigation and classification of the family Sesiidae (clearwing moths). Important monographs covering the Palearctic and Nearctic regions, and partly South America or South-East Asia have been made available (EICHLIN & DUCKWORTH 1988, EICHLIN 1986, 1989, 1995b and 1998, ŠPATENKA et al. 1999, KALLIES & ARITA 2004), and numerous descriptions of new taxa as well as revisions of genera and species described by earlier authors have been published, mainly dealing with the Oriental region (ARITA & GORBUNOV 1995c, ARITA & GORBUNOV 1996b etc.). -
1/11 FACULTAD DE VETERINARIA GRADO DE VETERINARIA Curso
FACULTAD DE VETERINARIA GRADO DE VETERINARIA Curso 2015/16 Asignatura: MICROBIOLOGÍA E INMUNOLOGÍA DENOMINACIÓN DE LA ASIGNATURA Denominación: MICROBIOLOGÍA E INMUNOLOGÍA Código: 101463 Plan de estudios: GRADO DE VETERINARIA Curso: 2 Denominación del módulo al que pertenece: FORMACIÓN BÁSICA COMÚN Materia: MICROBIOLOGÍA E INMUNOLOGÍA Carácter: BASICA Duración: ANUAL Créditos ECTS: 12 Horas de trabajo presencial: 120 Porcentaje de presencialidad: 40% Horas de trabajo no presencial: 180 Plataforma virtual: UCO MOODLE DATOS DEL PROFESORADO __ Nombre: GARRIDO JIMENEZ, MARIA ROSARIO (Coordinador) Centro: Veterinaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 3ª Planta E-Mail: [email protected] Teléfono: 957218718 _ Nombre: SERRANO DE BURGOS, ELENA (Coordinador) Centro: Veterinaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 3ª Planta E-Mail: [email protected] Teléfono: 957218718 _ Nombre: HUERTA LORENZO, MARIA BELEN Centro: Veterianaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 2ª Planta E-Mail: [email protected] Teléfono: 957212635 _ DATOS ESPECÍFICOS DE LA ASIGNATURA REQUISITOS Y RECOMENDACIONES Requisitos previos establecidos en el plan de estudios Ninguno Recomendaciones 1/11 MICROBIOLOGÍA E INMUNOLOGÍA Curso 2015/16 Se recomienda haber cursado las asignaturas de Biología Molecular Animal y Vegetal, Bioquímica, Citología e Histología y Anatomía Sistemática. COMPETENCIAS CE23 Estudio de los microorganismos que afectan a los animales y de aquellos que tengan una aplicación industrial, biotecnológica o ecológica. CE24 Bases y aplicaciones técnicas de la respuesta inmune. OBJETIVOS Los siguientes objetivos recogen las recomendaciones de la OIE para la formación del veterinario: 1. Abordar el concepto actual de Microbiología e Inmunología, la trascendencia de su evolución histórica y las líneas de interés o investigación futuras. -
Viruses 2015, 7, 456-479; Doi:10.3390/V7020456 OPEN ACCESS
Viruses 2015, 7, 456-479; doi:10.3390/v7020456 OPEN ACCESS viruses ISSN 1999-4915 www.mdpi.com/journal/viruses Article In Search of Pathogens: Transcriptome-Based Identification of Viral Sequences from the Pine Processionary Moth (Thaumetopoea pityocampa) Agata K. Jakubowska 1, Remziye Nalcacioglu 2, Anabel Millán-Leiva 3, Alejandro Sanz-Carbonell 1, Hacer Muratoglu 4, Salvador Herrero 1,* and Zihni Demirbag 2,* 1 Department of Genetics, Universitat de València, Dr Moliner 50, 46100 Burjassot, Spain; E-Mails: [email protected] (A.K.J.); [email protected] (A.S.-C.) 2 Department of Biology, Faculty of Sciences, Karadeniz Technical University, 61080 Trabzon, Turkey; E-Mail: [email protected] 3 Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” (IHSM-UMA-CSIC), Consejo Superior de Investigaciones Científicas, Estación Experimental “La Mayora”, Algarrobo-Costa, 29750 Málaga, Spain; E-Mail: [email protected] 4 Department of Molecular Biology and Genetics, Faculty of Sciences, Karadeniz Technical University, 61080 Trabzon, Turkey; E-Mail: [email protected] * Authors to whom correspondence should be addressed; E-Mails: [email protected] (S.H.); [email protected] (Z.D.); Tel.: +34-96-354-3006 (S.H.); +90-462-377-3320 (Z.D.); Fax: +34-96-354-3029 (S.H.); +90-462-325-3195 (Z.D.). Academic Editors: John Burand and Madoka Nakai Received: 29 November 2014 / Accepted: 13 January 2015 / Published: 23 January 2015 Abstract: Thaumetopoea pityocampa (pine processionary moth) is one of the most important pine pests in the forests of Mediterranean countries, Central Europe, the Middle East and North Africa. Apart from causing significant damage to pinewoods, T. -
Cuestionario A1-T67
JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI RI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI J I JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JR JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI RI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI J I JRI JRI JRI JRI JRI JRI JRI JRIGOBIERNO JRI JRI JRI JRI JRI JRI JRI JRI JRIMINISTERIO JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JR JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI RI JRI JRI JRI JRI JRI JRI JRI JRIDE JRI JRIESPAÑA JRI JRI JRI JRI JRI JRI DEJRI JRI CIENCIA JRI JRI JRI JRI JRI E JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI J I JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI JRI -
The Cause of Reduced Growth of Manduca Sexta Larvae on a Low-Water Diet: Increased Metabolic Processing Costs Or Nutrient Limitation?
J. Insecl Physiol. Vol. 34, No. 6, pp. 515-525, 1988 0022-1910/88 $3.00 + 0.00 Printed in Great Britain. All rights reserved Copyright 0 1988 Pergamon Press plc THE CAUSE OF REDUCED GROWTH OF MANDUCA SEXTA LARVAE ON A LOW-WATER DIET: INCREASED METABOLIC PROCESSING COSTS OR NUTRIENT LIMITATION? MICHAEL M. MARTIN and HEIDI M. VAN’T HOF Department of Biology, University of Michigan, Ann Arbor, MI 48109, U.S.A. (Received 28 July 1987; revised 9 November 1987) Abstract-Relative growth rates and nitrogen accumulation rates are lower for third-instar ~Uanduca sexta larvae on an artificial diet containing 65% water than on one containing 82% water, due to reduced efficiencies of conversion of digested food and digested nitrogen into larval biomass. Uric acid production is [email protected] greater, and non-feeding respiration rates 16.0% higher in the larvae on the low-water diet. Food is the major source of water for the larvae, with metabolic water making only a minor contribution to water input. Faecal excretion is the major avenue of water loss, although a significant amount of water is also lost by transpiration. Larvae from the low-water diet retain and use a higher percentage of the water they gain than larvae from the high-water diet (49.4% vs 41.9%). They produce much drier faeces (48.1% water vs 77.3% water), and, because their tissues are less hydrated (81.3% water vs 88.1% water), they synthesize 70% more new, fully hydrated tissue from a given amount of water than larvae from the high-water diet. -
Evidence to Support Safe Return to Clinical Practice by Oral Health Professionals in Canada During the COVID-19 Pandemic: a Repo
Evidence to support safe return to clinical practice by oral health professionals in Canada during the COVID-19 pandemic: A report prepared for the Office of the Chief Dental Officer of Canada. November 2020 update This evidence synthesis was prepared for the Office of the Chief Dental Officer, based on a comprehensive review under contract by the following: Paul Allison, Faculty of Dentistry, McGill University Raphael Freitas de Souza, Faculty of Dentistry, McGill University Lilian Aboud, Faculty of Dentistry, McGill University Martin Morris, Library, McGill University November 30th, 2020 1 Contents Page Introduction 3 Project goal and specific objectives 3 Methods used to identify and include relevant literature 4 Report structure 5 Summary of update report 5 Report results a) Which patients are at greater risk of the consequences of COVID-19 and so 7 consideration should be given to delaying elective in-person oral health care? b) What are the signs and symptoms of COVID-19 that oral health professionals 9 should screen for prior to providing in-person health care? c) What evidence exists to support patient scheduling, waiting and other non- treatment management measures for in-person oral health care? 10 d) What evidence exists to support the use of various forms of personal protective equipment (PPE) while providing in-person oral health care? 13 e) What evidence exists to support the decontamination and re-use of PPE? 15 f) What evidence exists concerning the provision of aerosol-generating 16 procedures (AGP) as part of in-person -
Niakha Virus: a Novel Member of the Family Rhabdoviridae Isolated from Phlebotomine Sandflies in Senegal
Virology 444 (2013) 80–89 Contents lists available at ScienceDirect Virology journal homepage: www.elsevier.com/locate/yviro Niakha virus: A novel member of the family Rhabdoviridae isolated from phlebotomine sandflies in Senegal Nikos Vasilakis a,b,c,n, Steven Widen d, Sandra V. Mayer a, Robert Seymour a, Thomas G. Wood d, Vsevolov Popov a, Hilda Guzman a, Amelia P.A. Travassos da Rosa a, Elodie Ghedin e, Edward C. Holmes f,g, Peter J. Walker h, Robert B. Tesh a,b,c a Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, Galveston, USA b Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555-0609, USA c Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555-0610, USA d Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555-1079, USA e Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA f Sydney Emerging Infections & Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney NSW 2006, Australia g Fogarty International Center, National Institutes of Health, Bethesda, MD, USA h CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong VIC 3220, Australia article info abstract Article history: Members of the family Rhabdoviridae have been assigned to eight genera but many remain unassigned. Received 8 February 2013 Rhabdoviruses have a remarkably diverse host range that includes terrestrial and marine animals, Returned to author for revisions invertebrates and plants. Transmission of some rhabdoviruses often requires an arthropod vector, such as 21 May 2013 mosquitoes, midges, sandflies, ticks, aphids and leafhoppers, in which they replicate. -
Rhabdoviridae.Pdf
1 Rhabdoviridae Taxonomy Realm- Ribovira Kingdom- Orthornavirae Phylum- Negarnaviricota Subphylum-Haploviricotina Class- Monjiviricetes Order- Mononegaviriales Family- Rhabdoviridae Genus- Lyssavirus Genus-Ephemerovirus Rhabdoviridae: The family Derivation of names Rhabdoviridae: from rhabdos (Greek) meaning rod, referring to virion morphology. Member taxa Vertebrate host Lyssavirus Novirhabdovirus Perhabdovirus Sprivivirus Tupavirus Vertebrate host, arthropod vector Prepared by Dr. Vandana Gupta Page 1 2 Curiovirus Ephemerovirus Hapavirus Ledantevirus Sripuvirus Tibrovirus Vesiculovirus Invertebrate host Almendravirus Alphanemrhavirus Caligrhavirus Sigmavirus Plant host Cytorhabdovirus Dichorhavirus Nucleorhabdovirus Varicosavirus The family Rhabdoviridae includes 20 genera and 144 species of viruses with negative-sense, single-stranded RNA genomes of approximately 10–16 kb. Virions are typically enveloped with bullet-shaped or bacilliform morphology but non-enveloped filamentous virions have also been reported. The genomes are usually (but not always) single RNA molecules with partially complementary termini. Almost all rhabdovirus genomes have 5 genes encoding the structural proteins (N, P, M, G and L); however, many rhabdovirus genomes encode other proteins in additional genes or in alternative open reading frames (ORFs) within the structural protein genes. The family is ecologically diverse with members infecting plants or animals including mammals, birds, reptiles or fish. Rhabdoviruses are also detected in invertebrates, -
Biosafety in Microbiological and Biomedical Laboratories—6Th Edition
Section VIII-A: Bacterial Agents Bacillus anthracis Bacillus anthracis, a Gram-positive, non-hemolytic, and non-motile bacillus, is the etiologic agent of anthrax, an acute bacterial disease among wild and domestic mammals, including humans. Like all members of the genus Bacillus, under adverse conditions, B. anthracis has the ability to produce spores that allow the organism to persist for long periods (i.e., years), withstanding heat and drying, until the return of more favorable conditions for vegetative growth.1 It is because of this ability to produce spores coupled with significant pathogenic potential in humans that this organism is considered one of the most serious and threatening biowarfare or bioterrorism agents.2 Most mammals are susceptible to anthrax; it mostly affects herbivores that ingest spores from contaminated soil and, to a lesser extent, carnivores that scavenge on the carcasses of diseased animals. In the United States, it occurs sporadically in animals in parts of the West, Midwest, and Southwest. Human case rates for anthrax are highest in Africa and central and southern Asia.3 The infectious dose varies greatly from species to species and is route-dependent. The inhalation anthrax infectious dose (ID) for humans has been primarily extrapolated from inhalation challenges of non-human primates (NHPs) or studies done in contaminated wool mills. Estimates vary greatly but the median lethal dose (LD50) is likely within the range of 2,500–55,000 spores.4 It is believed that very few spores (ten or fewer) are required for cutaneous anthrax infection.5 Anthrax cases have been rare in the United States since the first half of the 20th century. -
Multipartite Viruses: Organization, Emergence and Evolution
UNIVERSIDAD AUTÓNOMA DE MADRID FACULTAD DE CIENCIAS DEPARTAMENTO DE BIOLOGÍA MOLECULAR MULTIPARTITE VIRUSES: ORGANIZATION, EMERGENCE AND EVOLUTION TESIS DOCTORAL Adriana Lucía Sanz García Madrid, 2019 MULTIPARTITE VIRUSES Organization, emergence and evolution TESIS DOCTORAL Memoria presentada por Adriana Luc´ıa Sanz Garc´ıa Licenciada en Bioqu´ımica por la Universidad Autonoma´ de Madrid Supervisada por Dra. Susanna Manrubia Cuevas Centro Nacional de Biotecnolog´ıa (CSIC) Memoria presentada para optar al grado de Doctor en Biociencias Moleculares Facultad de Ciencias Departamento de Biolog´ıa Molecular Universidad Autonoma´ de Madrid Madrid, 2019 Tesis doctoral Multipartite viruses: Organization, emergence and evolution, 2019, Madrid, Espana. Memoria presentada por Adriana Luc´ıa-Sanz, licenciada en Bioqumica´ y con un master´ en Biof´ısica en la Universidad Autonoma´ de Madrid para optar al grado de doctor en Biociencias Moleculares del departamento de Biolog´ıa Molecular en la facultad de Ciencias de la Universidad Autonoma´ de Madrid Supervisora de tesis: Dr. Susanna Manrubia Cuevas. Investigadora Cient´ıfica en el Centro Nacional de Biotecnolog´ıa (CSIC), C/ Darwin 3, 28049 Madrid, Espana. to the reader CONTENTS Acknowledgments xi Resumen xiii Abstract xv Introduction xvii I.1 What is a virus? xvii I.2 What is a multipartite virus? xix I.3 The multipartite lifecycle xx I.4 Overview of this thesis xxv PART I OBJECTIVES PART II METHODOLOGY 0.5 Database management for constructing the multipartite and segmented datasets 3 0.6 Analytical