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1/11 FACULTAD DE VETERINARIA GRADO DE VETERINARIA Curso
FACULTAD DE VETERINARIA GRADO DE VETERINARIA Curso 2015/16 Asignatura: MICROBIOLOGÍA E INMUNOLOGÍA DENOMINACIÓN DE LA ASIGNATURA Denominación: MICROBIOLOGÍA E INMUNOLOGÍA Código: 101463 Plan de estudios: GRADO DE VETERINARIA Curso: 2 Denominación del módulo al que pertenece: FORMACIÓN BÁSICA COMÚN Materia: MICROBIOLOGÍA E INMUNOLOGÍA Carácter: BASICA Duración: ANUAL Créditos ECTS: 12 Horas de trabajo presencial: 120 Porcentaje de presencialidad: 40% Horas de trabajo no presencial: 180 Plataforma virtual: UCO MOODLE DATOS DEL PROFESORADO __ Nombre: GARRIDO JIMENEZ, MARIA ROSARIO (Coordinador) Centro: Veterinaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 3ª Planta E-Mail: [email protected] Teléfono: 957218718 _ Nombre: SERRANO DE BURGOS, ELENA (Coordinador) Centro: Veterinaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 3ª Planta E-Mail: [email protected] Teléfono: 957218718 _ Nombre: HUERTA LORENZO, MARIA BELEN Centro: Veterianaria Departamento: SANIDAD ANIMAL área: SANIDAD ANIMAL Ubicación del despacho: Edificio Sanidad Animal 2ª Planta E-Mail: [email protected] Teléfono: 957212635 _ DATOS ESPECÍFICOS DE LA ASIGNATURA REQUISITOS Y RECOMENDACIONES Requisitos previos establecidos en el plan de estudios Ninguno Recomendaciones 1/11 MICROBIOLOGÍA E INMUNOLOGÍA Curso 2015/16 Se recomienda haber cursado las asignaturas de Biología Molecular Animal y Vegetal, Bioquímica, Citología e Histología y Anatomía Sistemática. COMPETENCIAS CE23 Estudio de los microorganismos que afectan a los animales y de aquellos que tengan una aplicación industrial, biotecnológica o ecológica. CE24 Bases y aplicaciones técnicas de la respuesta inmune. OBJETIVOS Los siguientes objetivos recogen las recomendaciones de la OIE para la formación del veterinario: 1. Abordar el concepto actual de Microbiología e Inmunología, la trascendencia de su evolución histórica y las líneas de interés o investigación futuras. -
Viruses 2015, 7, 456-479; Doi:10.3390/V7020456 OPEN ACCESS
Viruses 2015, 7, 456-479; doi:10.3390/v7020456 OPEN ACCESS viruses ISSN 1999-4915 www.mdpi.com/journal/viruses Article In Search of Pathogens: Transcriptome-Based Identification of Viral Sequences from the Pine Processionary Moth (Thaumetopoea pityocampa) Agata K. Jakubowska 1, Remziye Nalcacioglu 2, Anabel Millán-Leiva 3, Alejandro Sanz-Carbonell 1, Hacer Muratoglu 4, Salvador Herrero 1,* and Zihni Demirbag 2,* 1 Department of Genetics, Universitat de València, Dr Moliner 50, 46100 Burjassot, Spain; E-Mails: [email protected] (A.K.J.); [email protected] (A.S.-C.) 2 Department of Biology, Faculty of Sciences, Karadeniz Technical University, 61080 Trabzon, Turkey; E-Mail: [email protected] 3 Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” (IHSM-UMA-CSIC), Consejo Superior de Investigaciones Científicas, Estación Experimental “La Mayora”, Algarrobo-Costa, 29750 Málaga, Spain; E-Mail: [email protected] 4 Department of Molecular Biology and Genetics, Faculty of Sciences, Karadeniz Technical University, 61080 Trabzon, Turkey; E-Mail: [email protected] * Authors to whom correspondence should be addressed; E-Mails: [email protected] (S.H.); [email protected] (Z.D.); Tel.: +34-96-354-3006 (S.H.); +90-462-377-3320 (Z.D.); Fax: +34-96-354-3029 (S.H.); +90-462-325-3195 (Z.D.). Academic Editors: John Burand and Madoka Nakai Received: 29 November 2014 / Accepted: 13 January 2015 / Published: 23 January 2015 Abstract: Thaumetopoea pityocampa (pine processionary moth) is one of the most important pine pests in the forests of Mediterranean countries, Central Europe, the Middle East and North Africa. Apart from causing significant damage to pinewoods, T. -
Evidence to Support Safe Return to Clinical Practice by Oral Health Professionals in Canada During the COVID-19 Pandemic: a Repo
Evidence to support safe return to clinical practice by oral health professionals in Canada during the COVID-19 pandemic: A report prepared for the Office of the Chief Dental Officer of Canada. November 2020 update This evidence synthesis was prepared for the Office of the Chief Dental Officer, based on a comprehensive review under contract by the following: Paul Allison, Faculty of Dentistry, McGill University Raphael Freitas de Souza, Faculty of Dentistry, McGill University Lilian Aboud, Faculty of Dentistry, McGill University Martin Morris, Library, McGill University November 30th, 2020 1 Contents Page Introduction 3 Project goal and specific objectives 3 Methods used to identify and include relevant literature 4 Report structure 5 Summary of update report 5 Report results a) Which patients are at greater risk of the consequences of COVID-19 and so 7 consideration should be given to delaying elective in-person oral health care? b) What are the signs and symptoms of COVID-19 that oral health professionals 9 should screen for prior to providing in-person health care? c) What evidence exists to support patient scheduling, waiting and other non- treatment management measures for in-person oral health care? 10 d) What evidence exists to support the use of various forms of personal protective equipment (PPE) while providing in-person oral health care? 13 e) What evidence exists to support the decontamination and re-use of PPE? 15 f) What evidence exists concerning the provision of aerosol-generating 16 procedures (AGP) as part of in-person -
Niakha Virus: a Novel Member of the Family Rhabdoviridae Isolated from Phlebotomine Sandflies in Senegal
Virology 444 (2013) 80–89 Contents lists available at ScienceDirect Virology journal homepage: www.elsevier.com/locate/yviro Niakha virus: A novel member of the family Rhabdoviridae isolated from phlebotomine sandflies in Senegal Nikos Vasilakis a,b,c,n, Steven Widen d, Sandra V. Mayer a, Robert Seymour a, Thomas G. Wood d, Vsevolov Popov a, Hilda Guzman a, Amelia P.A. Travassos da Rosa a, Elodie Ghedin e, Edward C. Holmes f,g, Peter J. Walker h, Robert B. Tesh a,b,c a Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, Galveston, USA b Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555-0609, USA c Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555-0610, USA d Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555-1079, USA e Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA f Sydney Emerging Infections & Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney NSW 2006, Australia g Fogarty International Center, National Institutes of Health, Bethesda, MD, USA h CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong VIC 3220, Australia article info abstract Article history: Members of the family Rhabdoviridae have been assigned to eight genera but many remain unassigned. Received 8 February 2013 Rhabdoviruses have a remarkably diverse host range that includes terrestrial and marine animals, Returned to author for revisions invertebrates and plants. Transmission of some rhabdoviruses often requires an arthropod vector, such as 21 May 2013 mosquitoes, midges, sandflies, ticks, aphids and leafhoppers, in which they replicate. -
Rhabdoviridae.Pdf
1 Rhabdoviridae Taxonomy Realm- Ribovira Kingdom- Orthornavirae Phylum- Negarnaviricota Subphylum-Haploviricotina Class- Monjiviricetes Order- Mononegaviriales Family- Rhabdoviridae Genus- Lyssavirus Genus-Ephemerovirus Rhabdoviridae: The family Derivation of names Rhabdoviridae: from rhabdos (Greek) meaning rod, referring to virion morphology. Member taxa Vertebrate host Lyssavirus Novirhabdovirus Perhabdovirus Sprivivirus Tupavirus Vertebrate host, arthropod vector Prepared by Dr. Vandana Gupta Page 1 2 Curiovirus Ephemerovirus Hapavirus Ledantevirus Sripuvirus Tibrovirus Vesiculovirus Invertebrate host Almendravirus Alphanemrhavirus Caligrhavirus Sigmavirus Plant host Cytorhabdovirus Dichorhavirus Nucleorhabdovirus Varicosavirus The family Rhabdoviridae includes 20 genera and 144 species of viruses with negative-sense, single-stranded RNA genomes of approximately 10–16 kb. Virions are typically enveloped with bullet-shaped or bacilliform morphology but non-enveloped filamentous virions have also been reported. The genomes are usually (but not always) single RNA molecules with partially complementary termini. Almost all rhabdovirus genomes have 5 genes encoding the structural proteins (N, P, M, G and L); however, many rhabdovirus genomes encode other proteins in additional genes or in alternative open reading frames (ORFs) within the structural protein genes. The family is ecologically diverse with members infecting plants or animals including mammals, birds, reptiles or fish. Rhabdoviruses are also detected in invertebrates, -
Biosafety in Microbiological and Biomedical Laboratories—6Th Edition
Section VIII-A: Bacterial Agents Bacillus anthracis Bacillus anthracis, a Gram-positive, non-hemolytic, and non-motile bacillus, is the etiologic agent of anthrax, an acute bacterial disease among wild and domestic mammals, including humans. Like all members of the genus Bacillus, under adverse conditions, B. anthracis has the ability to produce spores that allow the organism to persist for long periods (i.e., years), withstanding heat and drying, until the return of more favorable conditions for vegetative growth.1 It is because of this ability to produce spores coupled with significant pathogenic potential in humans that this organism is considered one of the most serious and threatening biowarfare or bioterrorism agents.2 Most mammals are susceptible to anthrax; it mostly affects herbivores that ingest spores from contaminated soil and, to a lesser extent, carnivores that scavenge on the carcasses of diseased animals. In the United States, it occurs sporadically in animals in parts of the West, Midwest, and Southwest. Human case rates for anthrax are highest in Africa and central and southern Asia.3 The infectious dose varies greatly from species to species and is route-dependent. The inhalation anthrax infectious dose (ID) for humans has been primarily extrapolated from inhalation challenges of non-human primates (NHPs) or studies done in contaminated wool mills. Estimates vary greatly but the median lethal dose (LD50) is likely within the range of 2,500–55,000 spores.4 It is believed that very few spores (ten or fewer) are required for cutaneous anthrax infection.5 Anthrax cases have been rare in the United States since the first half of the 20th century. -
Evidence to Support Safe Return to Clinical Practice by Oral Health Professionals in Canada During the COVID- 19 Pandemic: A
Evidence to support safe return to clinical practice by oral health professionals in Canada during the COVID- 19 pandemic: A report prepared for the Office of the Chief Dental Officer of Canada. March 2021 update This evidence synthesis was prepared for the Office of the Chief Dental Officer, based on a comprehensive review under contract by the following: Raphael Freitas de Souza, Faculty of Dentistry, McGill University Paul Allison, Faculty of Dentistry, McGill University Lilian Aboud, Faculty of Dentistry, McGill University Martin Morris, Library, McGill University March 31, 2021 1 Contents Evidence to support safe return to clinical practice by oral health professionals in Canada during the COVID-19 pandemic: A report prepared for the Office of the Chief Dental Officer of Canada. .................................................................................................................................. 1 Foreword to the second update ............................................................................................. 4 Introduction ............................................................................................................................. 5 Project goal............................................................................................................................. 5 Specific objectives .................................................................................................................. 6 Methods used to identify and include relevant literature ...................................................... -
Patogenicidad Microbiana En Medicina Veterinaria Volumen: Virología
Patogenicidad microbiana en Medicina Veterinaria Volumen: Virología Fabiana A. Moredo, Alejandra E. Larsen, Nestor O. Stanchi (Coordinadores) FACULTAD DE CIENCIAS VETERINARIAS PATOGENICIDAD MICROBIANA EN MEDICINA VETERINARIA VOLUMEN: VIROLOGÍA Fabiana A. Moredo Alejandra E. Larsen Nestor O. Stanchi (Coordinadores) Facultad de Ciencias Veterinarias 1 A nuestras familias 2 Agradecimientos Nuestro agradecimiento a todos los colegas docentes de la Facultad de Ciencias Veterinarias y en especial a la Universidad Nacional de La Plata por darnos esta oportunidad. 3 Índice VOLUMEN 2 Virología Capítulo 1 Características generales de los virus Cecilia M. Galosi, Nadia A. Fuentealba____________________________________________6 Capítulo 2 Arterivirus Germán E. Metz y María M. Abeyá______________________________________________28 Capítulo 3 Herpesvirus Cecilia M. Galosi, María E. Bravi, Mariela R. Scrochi ________________________________37 Capítulo 4 Orthomixovirus Guillermo H. Sguazza y María E. Bravi___________________________________________49 Capítulo 5 Paramixovirus Marco A. Tizzano____________________________________________________________61 Capítulo 6 Parvovirus Nadia A Fuentealba, María S. Serena____________________________________________71 Capítulo 7 Retrovirus Carlos J. Panei, Viviana Cid de la Paz____________________________________________81 Capítulo 8 Rhabdovirus Marcelo R. Pecoraro, Leandro Picotto____________________________________________92 Capítulo 9 Togavirus María G. Echeverría, María Laura Susevich______________________________________104 -
Merida Virus, a Putative Novel Rhabdovirus Discovered in Culex and Ochlerotatus Spp
Journal of General Virology (2016), 97, 977–987 DOI 10.1099/jgv.0.000424 Merida virus, a putative novel rhabdovirus discovered in Culex and Ochlerotatus spp. mosquitoes in the Yucatan Peninsula of Mexico Jermilia Charles,1 Andrew E. Firth,2 Maria A. Loron˜o-Pino,3 Julian E. Garcia-Rejon,3 Jose A. Farfan-Ale,3 W. Ian Lipkin,4 Bradley J. Blitvich1 and Thomas Briese4 Correspondence 1Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Bradley J. Blitvich Iowa State University, Ames, IA, USA [email protected] 2Department of Pathology, University of Cambridge, Cambridge, UK 3Laboratorio de Arbovirologı´a, Centro de Investigaciones Regionales Dr Hideyo Noguchi, Universidad Auto´noma de Yucata´n, Me´rida, Yucata´n, Me´xico 4Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA Sequences corresponding to a putative, novel rhabdovirus [designated Merida virus (MERDV)] were initially detected in a pool of Culex quinquefasciatus collected in the Yucatan Peninsula of Mexico. The entire genome was sequenced, revealing 11 798 nt and five major ORFs, which encode the nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G) and RNA-dependent RNA polymerase (L). The deduced amino acid sequences of the N, G and L proteins have no more than 24, 38 and 43 % identity, respectively, to the corresponding sequences of all other known rhabdoviruses, whereas those of the P and M proteins have no significant identity with any sequences in GenBank and their identity is only suggested based on their genome position. Using specific reverse transcription-PCR assays established from the genome sequence, 27 571 C. -
Interactions Between the Rabies Virus and LC8
AN ABSTRACT OF THE DISSERTATION OF Nathan E. Jespersen for the degree of Doctor of Philosophy in Biochemistry and Biophysics presented on September 10, 2019. Title: Viral Targeting of Host Hubs: Interactions between the Rabies Virus and LC8 Abstract approved: ______________________________________________________ Elisar J. Barbar As obligate intracellular parasites, viruses rely on host machinery for their own reproduction. Viruses are therefore required to interact with a wide variety of host proteins, despite limitations in viral genome size. The most parsimonious method of success is to hijack central and essential proteins, known as hub proteins. LC8 is a notable example of a hub protein, and has been shown to interact with more than 100 eukaryotic partners in various unrelated pathways. An increasing number of studies have noted interactions between LC8 and viruses, including the Ebola, rabies, and rotaviruses; however, LC8’s role within these systems is unclear. This thesis examines the structural and functional properties of hub proteins, with a particular focus on LC8 and its interactions with the rabies virus. Three chapters of original work include two primary research reports and one review/opinion piece. The first research report, Chapter 2, structurally characterizes the interaction between LC8 and the rabies virus phosphoprotein (RavP). We use insights gleaned from our structural studies to predict and test potential roles for LC8 in the rabies virus infection cycle, and demonstrate that LC8 is important for efficient viral polymerase activity. Chapter 3 is an in-depth study of the LC8 recognition motif, where we examine both the structural and functional plasticity of LC8, and identify and validate many new LC8 interactions. -
Evidence to Support Safe Return to Clinical Practice
Evidence to support safe return to clinical practice by oral health professionals in Canada during the COVID-19 pandemic: A report prepared for the Office of the Chief Dental Officer of Canada. This evidence synthesis was prepared for the Office of the Chief Dental Officer, based on a comprehensive review under contract by the following: Paul Allison, Faculty of Dentistry, McGill University Raphael Freitas de Souza, Faculty of Dentistry, McGill University Lilian Aboud, Faculty of Dentistry, McGill University Martin Morris, Library, McGill University July 31st, 2020 1 Contents Page Foreword 4 Background 5 Project goal and specific objectives 5 Methods used to identify and include relevant literature 6 Report structure 7 Report summary 7 Report results a) Which patients are at greater risk of the consequences of COVID-19 9 and so consideration should be given to delaying elective in-person oral health care? b) What are the signs and symptoms of COVID-19 that dental 10 professionals should screen for prior to providing in-person oral health care? c) What evidence exists to support patient scheduling, waiting and 11 other non-treatment management measures for in-person oral health care? d) What evidence exists to support the use of various forms of 13 personal protective equipment (PPE) while providing in-person oral health care? e) What evidence exists to support the decontamination and re-use of 14 PPE? f) What evidence exists concerning the provision of aerosol- 14 generating procedures (AGP) as part of in-person oral health care? g) What -
Genetic Diversity, Development
GENETIC DIVERSITY, DEVELOPMENT OF IMPROVED DIAGNOSTIC ASSAYS AND EVIDENCE TOWARDS THE TARO PLANTHOPPER (TAROPHAGUS PROSERPINA) AS THE VECTOR FOR TARO VEIN CHLOROSIS VIRUS (TAVCV) IN HAWAII A THESIS SUBMITTED TO THE GRADUATE DIVISION OF THE UNIVERSITY OF HAWAI'I AT MĀNOA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE IN TROPICAL PLANT PATHOLOGY NOVEMBER 2016 By Riten Chand Gosai Thesis Committee: Michael Melzer, Chairperson John S. Hu Michael Shintaku Key words: Taro vein chlorosis virus, Taro planthopper, Tarophagus proserpina DEDICATION I dedicate this thesis, firstly, to the special people who cherished my achievements as their own and of the family; those whom now I cannot meet in person, ever, but treasure in my memories and occasionally meet in my dreams – my late paternal grandmother Satya Wati, my late father Dinesh Chandra Gosai, my late uncles Rakesh Chandra Gosai and Kamal Kumar and my late maternal grandfather Hari Prasad. I dedicate this thesis, next, to the people who I am fortunate enough to celebrate this journey of life with. People, who beyond the struggles, the qualifications and the end result mean the world to me. To la familia en Fiji, U. S. A., Australia, New Zealand, Canada and Samoa – this is for you! i ACKNOWLEDGEMENTS I express my sincere gratitude towards my thesis advisor, Dr. Michael Melzer, for his guidance, assistance and support throughout the course of this research project and my time at the University of Hawaiʻi – Mānoa. I consider myself fortunate and I am indebted. I also thank my committee members, Dr. John S.