Thin Layer Chromatographic Separation of Diacetylmorphine (Heroin) and Its Excipients: an Experimental Study
Research Article J Forensic Sci & Criminal Inves Volume - 8 Issue 3 - April 2018 Copyright © All rights are reserved by Mahesh Chand Meena DOI: 10.19080/JFSCI.2018.08.555736 Thin Layer Chromatographic Separation of Diacetylmorphine (Heroin) and Its Excipients: An Experimental Study Saloni Chadha1, Deepti Bhargava2, Mahesh Chand Meena3* and VB Ramteke4 1Tutor, Department of Forensic Medicine & Toxicology, Dr BSA Medical College & Hospital, Indraprastha University, India 2Senior Scientific Officer-II, Chemistry Division, Central Forensic Science Laboratory, India 3MD (Forensic Medicine), Assistant Professor, Department of Forensic Medicine & Toxicology, Dr BSA Medical College & Hospital, Indraprastha University, India 4SSO-I & HOD, Chemistry Division, Central Forensic Science Laboratory, India Submission: April 04, 2018; Published: April 17, 2018 *Corresponding author: Dr Mahesh Chand Meena, MD (Forensic Medicine), Assistant Professor, Department of Forensic Medicine & Toxicology, Dr BSA Medical College & Hospital, Indraprastha University, Rohini, Delhi, India, Email: Abstract Background Heroin is a well-known drug of abuse that is usually administered intravenously. However, smoking heroin has gained popularity samplesin many wereparts receivedof the world in sealed since transparent it was first plasticdescribed containers in Shanghai for qualitative in the 1920s. analysis Material of heroin and method- and its excipients. A total of 6Result-Out exhibits were of 16 examined systems, 11in systemslaboratory, are New capable Delhi of for resolving research opium work andand itsthe alkaloids, physical appearances9 systems are were capable noted of for resolving the samples opium as alkaloids a part of inthe illicit preliminary heroin and examination. 8 systems The are capable of resolving opium alkaloids and adulterants in illicit heroin. Conclusion In our study the best solvent systems are Ethyl acetate: benzene: acetonitrile: ammonia (25:30:40:5) and Toluene: acetone: ethanol: ammonia (20:20:3:1) for separation of opium alkaloids and adulterants.
[Show full text]