Genome Sequence and Genetic Diversity of the Common Carp, Cyprinus Carpio
ARTICLES OPEN Genome sequence and genetic diversity of the common carp, Cyprinus carpio Peng Xu1,10, Xiaofeng Zhang2,10, Xumin Wang3,10, Jiongtang Li1,10, Guiming Liu3,10, Youyi Kuang2,10, Jian Xu1,10, Xianhu Zheng2,10, Lufeng Ren3, Guoliang Wang3, Yan Zhang1, Linhe Huo3, Zixia Zhao1, Dingchen Cao2, Cuiyun Lu2, Chao Li2, Yi Zhou4, Zhanjiang Liu1,5, Zhonghua Fan3, Guangle Shan3, Xingang Li3, Shuangxiu Wu3, Lipu Song3, Guangyuan Hou1, Yanliang Jiang1, Zsigmond Jeney6, Dan Yu3, Li Wang3, Changjun Shao3, Lai Song3, Jing Sun3, Peifeng Ji1, Jian Wang1, Qiang Li1, Liming Xu1, Fanyue Sun5, Jianxin Feng7, Chenghui Wang8, Shaolin Wang9, Baosen Wang1, Yan Li1, Yaping Zhu1, Wei Xue1, Lan Zhao1, Jintu Wang1, Ying Gu2, Weihua Lv2, Kejing Wu3, Jingfa Xiao3, Jiayan Wu3, Zhang Zhang3, Jun Yu3 & Xiaowen Sun1,2 The common carp, Cyprinus carpio, is one of the most important cyprinid species and globally accounts for 10% of freshwater aquaculture production. Here we present a draft genome of domesticated C. carpio (strain Songpu), whose current assembly contains 52,610 protein-coding genes and approximately 92.3% coverage of its paleotetraploidized genome (2n = 100). The latest round of whole-genome duplication has been estimated to have occurred approximately 8.2 million years ago. Genome resequencing of 33 representative individuals from worldwide populations demonstrates a single origin for C. carpio in 2 subspecies (C. carpio Haematopterus and C. carpio carpio). Integrative genomic and transcriptomic analyses were used to identify loci potentially associated with traits including scaling patterns and skin color. In combination with the high-resolution genetic map, the draft genome paves the way for better molecular studies and improved genome-assisted breeding of C.
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