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Posters A-Z

Abendroth, Ulrike Presenter: Gregorova, Pavlina The multispecies conservation of oxidative stress-induced changes in 64 tRNA modifications

Akirtava, Christina Quantitative analysis of yeast Kozak variants for AUG and near-AUG 65 start codons using a massively parallel reporter assay

Albanese, Tanino Recycling of stalled complexes in the absence of 66 trans-

Alghoul, Fatima The mechanism of inhibition of cap-dependent translation by the 67 Translational Inhibitory Elements (TIE) a3 and a11 in Hox mRNAs

Amirbeigiarab, Susan Age-dependent dynamics of ribosomal in mouse brain 68

Andreev, Dmitry E A uORF in the Ago1 mRNA provides a rare example of >100 triplet long, 69 AUG-initiated translated uORF which is evolutionary conserved in placental mammals

Baharoglu, Zeynep Indole signaling triggers a new persistence mechanism involving RaiA 70 mediated translation slowdown in V. cholerae

Bailey, Mark Control of plastid ribosome biogenesis by the cytosolic ubiquitin E3 71 ligase NOT4

Barrera, Aldo hnRNPA1-induced stimulation of the HIV-1 IRES requires 72 PRMT5-associated methylation

Batchelder, Jake Ribosome biogenesis during cell cycle arrest fuels the 73 epithelial-to-mesenchymal transition

Beck, Heather The putative ribonucleolytic activity of P 74

Page 19 EMBO Workshop: Synthesis and Translational Control

Beckert, Bertrand The structure of the Drosophila 80S ribosome at 2.8 Å 75

Bellodi, Cristian The X-linked DDX3X RNA helicase dictates translation re-programming 76 and metastasis in melanoma

Bennison, Daniel Inhibition of ribosome-associated by (p)ppGpp in 77 Staphylococcus aureus

Berman, Andrea The LARP1 La-RRM module RNA-binding profile elaborates its 78 molecular roles in the cell

Beznoskova, Petra Cellular levels of human readthrough inducing tRNAs influence the final 79 production of functional p53 protein from PTC-containing mRNAs

Bhaskar, Varun Dynamics of uS19 C-terminal tail during the translation elongation cycle 80 in human

Biffo, Stefano Translational control of fatty liver disease 81

Blagojevic, Aleksandar Presenter: Schepetilnikov, Mikhail Regulation of TOR (Target of Rapamycin) function and intracellular 82 localization in plants

Boehringer, Daniel Mechanism of consecutive methylation of the 16S ribosomal RNA by 83 the conserved dimethyltransferase KsgA

Boileau, Etienne The cardiac landscape of RNA translation in the mouse 84

Borg, Anneli Reconstituting mitochondrial translation in vitro 85

Page 20 Posters A-Z

Borkar, Pranita PIP4K2A: A host kinase and parasite RNA binding protein 86

Boulay, Karine Targeted clearance of senescent cells by eIF4A inhibition towards 87 improving cancer therapy

Braselmann, Esther Imaging mRNA and non-coding RNA dynamics in live mammalian cells 88 with Riboglow, a fluorescence tagging platform

Breitenbach-Koller, Hannelore Presenter: Friedrich, Andreas Customized translational repair of skin protein Lamb3 PTC mutation in 89 rare disease Epidermolysis bullosa

Brocard, Michele Norovirus infection results in assembly of virus-specific G3BP1 granules 90 uncoupled from eIF2 signaling

Büscher, Magdalena Riboregulation of mammalian autophagy by the non-coding 91 vault RNA 1-1

Cairo Calzada, Albert Inhibition of protein translation is required for meiotic exit and transition 92 to pollen development in Arabidopsis

Cargnello, Marie Deciphering the role of the RNA-binding protein hnRNPU in 93 mTOR-dependent mRNA translation

Caruso, Marino Translational control of mitochondrial biogenesis during hepatogenic 94 differentiation

Chaparro, Visnu Reprogramming of macrophage mRNA translation during infection by 95 the protozoan parasite Leishmania donovani

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Chen, Liuh-yow Extrachromosomal telomere DNA triggers type I interferon response 96

Chhipi Shrestha, Jagat Splicing perturbation leads to proteotoxicity and translation inhibition 97

Chiba, Shinobu A -dependent ribosome rescue mechanism in 98 Gram-positive

Clayton, Christine E. Control of Trypanosoma brucei differentiation by RNA binding proteins 99

Crowe-McAuliffe, Caillan Structures of -resistance ABCF proteins in complex with the 100 ribosome

Daberger, Jan Co-translational folding of a toxin-antitoxin protein complex 101

Das, Anindhya Sundar Large ribosomal subunit protein RPL22 surveils CCL2 expression by 102 post-transcriptional regulation in LPS-mediated inflammation

Das, Sarada Molecular mechanisms of stress granule assembly and disassembly 103

Dasgupta, Ananya Determining molecular signatures of cryptoccocal response to Zoloft 104 (Sertraline) using a global approach de Boer, Ruben subunit eIF2B5 is involved in 105 intestinal epithelial stemness and is potentially rate limiting in hyperproliferative conditions

Page 22 Posters A-Z

Denk, Sarah Impact of the c-MYC internal ribosome entry site on intestinal 106 regeneration and colorectal tumorigenesis

Derylo, Kamil New alternatively spliced isoform of ribosomal uL10 protein 107

Dever, Thomas E. Ascorbate-sensing uORF Controls GDP-L-galactose phosphorylase 108 (GGP) mRNA Translation

Diamond, Paige Elucidating the contribution of the cap-binding protein (eIF4E) on 109 translation regulation in yeast

Djuranovic, Sergej Impact of the starting amino acids, translation factors and ribosome exit 110 channel on 5' translational ramp

Dmitriev, Sergey E. Ribosome profiling of mouse organs reveals translational deregulation of 111 protein synthesis machinery during aging

Dong, Yihan The role of TOR in plant translation initiation control 112

Donlin-Asp, Paul Localization and dynamics of translation at the synapse 113

Draycott, Austin S. Protein output control by differential binding to eukaryotic initiation 114 factor 4F

Egler, Franziska Mechanisms of selective translation stimulation and suppression by the 115 multiple eIF4E isoforms of Trypanosoma brucei

Eiermann, Nina Identification of novel molecular switches regulating stress granule 116 oscillation during HCV infection

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Eiler, Daniel Cryo-EM structure of the 80S ribosome from the human gastrointestinal 117 parasite Giardia intestinalis

El Hachem, Najla Defining the mechanisms of selective mRNA translation regulation 118 during resistance of melanoma to targeted therapies

Eliseeva, Irina factor binding sites affect mTOR translational response 119

Enam, Syed Usman Determining factor requirements and release kinetics of the 2A ’s 120 StopGo activity

Evans, Harrison Decreased synthesis of ribosomal proteins in tauopathy revealed by 121 non-canonical labelling

Farabaugh, Philip J. Presenter: Joshi, Kartikeya Translational accuracy is regulated by of ribosomal 122 protein uS5 through multiple kinase pathways

Fatkhullin, Bulat X-ray structural studies of the complex ribosomal silencing factor S and 123 L14 from Staphylococcus aureus

Fenton, Darren Translation landscape of Kluyveromyces marxianus as revealed with 124 ribosome profiling

Fernandez, Samantha Identifying factors that regulate start site selection in mammalian cells 125 with CRISPRi

Fernández-García, Leandro Non-canonical cap-independent translation of the Dengue virus mRNA 126

Fischer, Niels Mechanism of ribosome rescue by ArfB 127

Page 24 Posters A-Z

Frydas, Alexandros Investigation of the role of GRN upstream open reading frames in 128 frontotemporal dementia

Fujita, Tomoya Genome-wide probing of ribosome conformations identified bacterial 129 translation arrests at rotated state

Fujiwara, Toru Genome-wide analysis of nitrogen-dependent 130 in sorghum

Fujiwara, Toshinobu Novel mechanism of ZFP36L1-mediated translation repression 131

Fusco, Claudia Can neurons spatially and temporally tune their protein synthesis 132 machinery?

Gentilella, Antonio mTOR inhibition reprograms the cellular to preserve the 133 anabolic capacity of the cell

Goscinska, Karolina Mechanisms of global translation modulation upon dysfunctional 134 mitochondria

Grela, Przemyslaw Presenter: Horbowicz-Drozdzal, Patrycja Interplay of ribosomal stalk P-proteins with ricin and trichosanthin, the 135 plant ribosome inactivating proteins

Grosso, Stefano An mTOR-dependent feedforward loop that couples oxidative 136 phosphorylation to mRNA translation, drives aberrant cell growth in malignant mesothelioma

Grudniewska, Magda The role of translation dynamics in ABC-transporter folding and stability 137

Page 25 EMBO Workshop: Protein Synthesis and Translational Control

Grund, Andrea The tumor suppressor TIP30 restricts cardiac growth and protects 138 from heart failure by inhibiting translational elongation

Gu, Sohyun Balancing stoichiometry of eIF4G and PABP occurs through alternate 139 conformations of PABP: eIF4G associates with monomeric mRNA-bound PABP, but not with dimeric RNA-free PABP

Gulay, Suna eIF4A and eIF4E interactions with distinct residues of the Ded1 140 N-terminus stimulate Ded1 function in translation initiation in vivo

Hanson, Johannes SeedTransNet-a network for the identification and validation of novel 141 translational regulator in seeds

Hauryliuk, Vasili A role for the Saccharomyces cerevisiae ABCF protein New1 during 142 translation termination

Hernández, Greco Diversification of the AUG codon context across eukaryotes 143

Herrmannová, Anna The eIF3d subunit of the human translation initiation factor eIF3 critically 144 promotes assembly of the pre-initiation complex

Hetzert, Bianca Conformational rearrangements of ABCE1 during ribosome recycling 145

Hines, Timothy Profiling transcription and translation in motor neurons from mouse 146 models of Charcot-Marie-Tooth disease

Hofhuis, Julia A functional readthrough extension targets malate dehydrogenase to 147 the peroxisome

Page 26 Posters A-Z

Horos, Rastislav Regulation of autophagy by RNA and vice versa 148

Hsieh, Andrew C. The androgen receptor regulates a druggable translational regulon in 149 advanced prostate cancer

Hsu, Chun-Chieh Antiviral protein viperin restricts viral replication of Zika virus and Kunjin 150 virus by inhibiting viral RNA translation

Hulea, Laura EIF4F links translation to energy stress response in cancer 151

Iadevaia, Valentina Regulation of RNA Granules by caliciviruses, from hijacking to novel 152 paracrine induction

Ivanov, Alexander Presenter: Shuvalova, Ekaterina PDCD4 enhances translation termination in vitro 153

Ivanov, Pavel Diverse mechanisms of translation inhibition by tRNA-derived 154 regulatory

Jansova, Denisa Imaging of single RNA molecule in mammalian oocyte 155

Jensen, Kirk New tools to probe mRNA translation in vivo 156

Joiret, Marc Protein translation rate modeling with extended TASEP incorporating 157 tRNAs modifications effects

Karki, Prajwal Translational readthrough of the large Maf traffic jam 158 in Drosophila melanogaster

Kashiwagi, Kazuhiro Structural basis of eIF2B regulation by eIF2 phosphorylation 159

Page 27 EMBO Workshop: Protein Synthesis and Translational Control

Kaushik, Kriti Role of non-coding RNAs in regulating IGF2BP3, an oncofetal RNA 160 binding protein

Khan, Yousuf Bioinformatic prediction of -1 ribosomal frameshifting sites 161

Khusainov, Iskander Role of potassium ions in structure and function of 70S ribosome as 162 revealed by long-wavelength X-ray diffraction

Kiltschewskij, Dylan Functional impact of excitation-associated miRNA on posttranscriptional 163 and translational dynamics in depolarised neurons

Kimura, Yusuke The gravity facilitates mitochondrial translation and ATP synthesis 164

Kiniry, Stephen J An internet portal for the exploration of ribosome profiling data 165

Kisly, Ivan The pleiotropic functions of proteins eL19 and eL24 in the eukaryotic 166 ribosome

Klaas, Oliver CRISPR/Cas9-mediated deletion of upstream open reading frames 167 (uORFs) reveals distinct patterns of endogenous and reporter-based uORF-mediated translational control

Knauer, Jan Felix A versatile cell-free protein production platform for the synthesis of 168 fungal enzymes

Knorr, Alexandra N-terminal acetyl transferases (NATs) and the interplay of factors at the 169 ribosomal tunnel exit

Page 28 Posters A-Z

König, Julian The RNA-binding ubiquitin ligase MKRN1 functions in 170 ribosome-associated quality control of poly(A) translation

Krogh, Nicolai RiboMeth-seq analysis of diffuse large B-cell lymphoma cell lines and 171 patient samples

Lapointe, Christopher Dynamics of translation initiation on viral mRNAs 172

Larsson, Daniel Structure of an E. coli 50S ribosome assembly intermediate, the 173 substrate of methyltransferase RlmF

Lee, Jung A Effects of Combretum quadrangulare on 174 2,4-Dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in BALB/c mice

Lee, Ying-Hue The role of RPL-24 isoforms in response to food deprivation stress in 175 tissues of C. elegans

Li, Xin Ribosomes guide initial piRNA processing on long single strand 176 precursor RNAs

Liendl, Lisa Nsun5 in ribosome function and mammalian healthy lifespan 177

Lilleorg, Silva On the importance of bacterial ribosome heterogeneity 178

Lorent, Julie Presenter: Furic, Luc Estrogen receptor alpha controls via translational 179 offsetting

Lorenzo Orts, Laura Concerted expression of a cell-cycle regulator and a metabolic enzyme 180 from a polycistronic transcript in plants

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Loughran, Gary Roadblock properties of ribosome stalling in AMD1 mRNA and its effect 181 on protein stability

Lu, Jian Function and adaptive evolution of uORFs in Drosophila 182

Makeeva, Desislava S. Sequestration of termination and recycling factors to stress granules 183 contributes to elevated stop-codon readthrough and translation reinitiation rates upon stress

Mangano, Kyle Analysis of the in vivo action of antimicrobials targeting protein synthesis 184

Mariotti, Marco Translational recoding: comparative genomics of selenocysteine, the 185 21st amino acid

Martin, Franck Deciphering the Repeat Associated non-AUG (RAN) translation initiation 186 mechanism from C9ORF72 transcripts in ALS/FTD patients

Martinez-Salas, Encarna A novel dimerization module in Gemin5 is critical for protein recruitment 187 and translation control

Marzi, Stefano S. aureus S1 is an RNA chaperone which promotes translation of 188 secreted virulence factors by modulating mRNA structures

Matcovitch Natan, Orit PSM: a novel technology for monitoring translation in mammalian cells 189

May, Gemma Presenter: McManus, Joel Analysis of uORF functions using a massively parallel reporter assay 190

Page 30 Posters A-Z

Meffert, Mollie Shaping plasticity with growth regulatory MiRNAs 191

Merker, Dorina The nascent interactome of the ribosome associated factor NAC 192 studied by selective ribosome profiling

Mikhaylova, Maria S. MIR transposition engendered dual coding capacity in POLG encoding 193 mitochondrial DNA polymerase

Mishima, Yuichiro Defining codon-mediated mRNA decay and No-go decay in zebrafish 194 embryos

Mohammad, Mahabub Pasha Scaffolder (eIF4G) in translation re-initiation 195

Moll, Isabella Expanding the bacterial proteome 196

Müller, Christine Ablation of uORF-dependent translation into C/EBPß-LIP extends 197 health- and lifespan in mice

Müller, Claudia Structural insights into bacterial ribosome rescue of non-stop 198 complexes

Nadimpalli, Hima-Priyanka Presenters: Coll, Olga; Guitart, Tanit Dicer-2 targets and complexes in translational control 199

Naito, Satoshi Reverse genetics-based biochemical studies of the ribosomal exit 200 tunnel constriction region on eukaryotic programed ribosome stalling systems

Namy, Olivier The importance of RNA modifications in translation fidelity 201

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Nedialkova, Danny D. Presenters: Nedialkova, Danny D.; Behrens, Drew High-resolution quantitative profiling of tRNA pools by mim-tRNAseq 202

Nevado, Rosa M Impaired protein synthesis as a contributor to accelerated 203 cardiovascular disease in Hutchinson-Gilford progeria syndrome

Nicholson, David The action of ribosome-targeting in pathogenic bacteria 204

Niederer, Rachel Direct analysis of ribosome targeting illuminates thousand-fold 205 regulation of translation initiation

Nieuwkoop, Thijs Improved protein production and codon optimization analyses in 206 by bicistronic design

Nikolay, Rainer Functionalization of pre-50S subunits by ObgE 207

Noble, Michelle MDH2 meets RNA: A study into the mechanisms and functions of this 208 interaction

Nürenberg-Goloub, Elina Structure, function and dynamics of ABCE1 in ribosome recycling 209

Oh, Joa Sub Anti-hyperlipidemic activity of Amomum tsao-ko Crevost et Lemarie 210 extract in C57BL/6 mice fed a high-carbohydrate diet

Osterman, Ilya Tetracenomycin – new inhibitor of the bacterial translation, which binds 211 in peptide tunnel close to binding site

Pareja Sánchez, Yerma Regulation of translation upon oxidative stress in yeast 212

Page 32 Posters A-Z

Pavlikova, Zuzana The role of glutamine tRNA primary sequence in recognition of the stop 213 codon and its influence on the readthrough efficiency

Perez-Martinez, Xochitl Defects on translation of the mitochondrial COX1 mRNA are bypassed 214 by a nuclear suppressor

Pilpel, Yitzhak Presenter: Dahan, Orna Systematic detection of amino acid substitutions in proteome reveals a 215 mechanistic basis of ribosome errors

Pospisek, Martin Messenger RNAs of the yeast cytoplasmic DNA virus-like elements 216 contain uncapped non-templated 5' poly(A) leaders and their expression is independent of eIF4E and Pab1

Postovit, Lynne-Marie Translational regulation of cancer cell plasticity 217

Poulis, Panagiotis Accumulation of late translocation intermediates correlates with 218 spontaneous frameshifting

Pradhan, Swagat Characterizing molecular mechanisms in infantile mitochondrial 219 cardiomyopathy

Prilepskaja, Terezie Investigating the role of human eIF3c and eIF3d in translation initiation 220

Quintas, Ana Presenter: Marini, Alberto Elevated expression of eIF4B in Diffuse Large B-Cell Lymphoma results 221 in remodelling of eIF4B-containing complexes and increased binding to 5’UTRs and coding regions

Rae, Christopher The movement of transfer-messenger RNA through the ribosome 222

Page 33 EMBO Workshop: Protein Synthesis and Translational Control

Ranjan, Namit Presenters: Ranjan, Namit; Blanchet, Sandra The function of fungal-specific elongation factor eEF3 223

Rapino, Francesca Uncovering the U34 tRNA modifying enzymes target proteome and its 224 impact in human disease

Ravi, Venkatraman Sirtuin 6 controls global protein synthesis through transcriptional 225 regulation of mTOR signaling

Reier, Kaspar Ribosomal proteins in Escherichia coli’s proteome in the stationary 226 growth phase

Relier, Sébastien Presenter: Bastide, Amandine FTO/m6Am axis controls cancer stem-like properties in colorectal 227 cancer by fine-tuning translation process

Relton, Emily Novel human iPSCs derived models to understand the regulation of 228 RNA granules in neurodegeneration

Renard, Eva Biophysical investigation of antibiotics targeting multi-drug resistant 229 pathogens

Rendleman, Justin A 5’ UTR hexamer motif interacts with ribosomes to modulate gene 230 expression in key stress response factors

Ricciardi, Sara Tight translational control of glycolysis and fatty acid metabolism 231 regulates the transition of CD4+ T cells from quiescence to metabolic remodelling

Ristau, Johannes RITA requires eIF2alpha-dependent modulation of mRNA translation for 232 its anti-cancer activity

Page 34 Posters A-Z

Roghanian, Mohammad The allosteric pppGpp binding site of Escherichia coli stringent factor 233 RelA

Rol Moreno, Javier Characterization of the 5’ IRES elements regulating the translation of 234 mRNAs encoding cancer-related factors

Roncero Sanchez, Ana-Maria Novel U34-tRNA modification targets highlight a new therapeutic 235 approach in triple negative breast cancer

Rothamel, Katherine The RNA-binding protein ELAVL1 determines the efficacy of an IRF3 236 induced innate immune response

Rundlet, Emily Mechanistic analysis of human tRNA selection by smFRET 237

Sajeev, Nikita Translational control of seed germination: Role of mRNA binding 238 proteins

Samsonova, Anastasiia Structural and functional insights into the activity of mammalian 239 cold-shock proteins

Sattlegger, Evelyn Presenter: Shanmugam, Renuka Towards the Gcn1 interactome. Evidence that Xrn1 is in complex with 240 Gcn1, and is required for full activation of Gcn2

Saurer, Martin Biogenesis of mitochondrial ribosomes in trypanosomes involves 241 formation of large assembly intermediates

Schenckbecher, Emma binding on bacterial ribosome : thermodynamic studies 242

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Schloßhauer, Jeffrey Qualifying a mutually orthogonal pyrrolysyl-tRNA synthetase-tRNA(Pyl) 243 pair for fluorescent labeling of membrane proteins in eukaryotic cell-free systems

Schmidt, Stefanie A MYC/GCN2/eIF2a negative feedback loop limits protein synthesis to 244 prevent MYC-dependent apoptosis in colorectal cancer

Schmidt, Tobias Distinct functions of DEAD-box helicases DDX6 and eIF4A2 in mRNA 245 deadenylation

Schosserer, Markus Two specific m5C-modifications of ribosomal RNA distinctly modulate 246 healthy lifespan and development

Schwarzl, Thomas Improved RNA-binding site analysis for ENCODE eCLIP data sets using 247 htseq-clip and DEWSeq

Sehrawat, Urmila EIF1A regulates translation of cell cycle 248

Sfakianos, Aristeidis eIF5A as a target for anti-cancer drug development 249

Sharma, Sandeep Presenter: Kaji, Akira Appearance of 40S particles containing 16S ribosomal RNA as a 250 possible reason for lethal effect of denatured Ts-RRF at lag Phase

Shields, Kathryn Presenter: Yap, M.-N. Frances Functional consequences of methylated bacterial ribosomes 251

Shih, Ming-Che The dynamic translational regulation in Arabidopsis under submergence 252

Shuvalov, Alexey Activity of human eRF1 isoforms in translation termination 253

Page 36 Posters A-Z

Silva, Joana The role of RNA translation in intestinal stem cells 254

Sinnadurai, Samantha Translation dysregulation is linked to epithelial-mesenchymal transition 255 (EMT) in primary human tumour tissues

Smirnova, Anna Deciphering the mechanics of translation control of ATF4 under stress 256

Smit, Wouter The intestinal epithelial global translational capacity is governed by 257 driver mutations of the adenoma-carcinoma sequence of colorectal cancer

So, Lomon Regulatory T cells impose translational remodeling in effector 258 CD4 T cells

Sotta, Naoyuki Genome-wide analysis of boron-dependent translational regulation in 259 plants

Stilinovic, Martina Ribonuclease Inhibitor (RNH1) regulates hematopoietic cell specific 260 translation

Stoneley, Mark Ribosomes stalled during genotoxic stress are resolved by a novel RNA 261 binding protein complex

Sur, Debpali Investigating enhanced expression of LINE-1 retrotransposon encoded 262 proteins in early onset of Oral squamous cell carcinoma

Swain, Kendra A global landscape of post-transcriptional regulators in Saccharomyces 263 cerevisiae

Page 37 EMBO Workshop: Protein Synthesis and Translational Control

Swirski, Michal Detection and quantification of protein variants with N-terminal 264 extensions containing mitochondrial targeting signals

Szaflarski, Witold The anticancer drug mitoxantrone is a protein inhibitor 265

Szkop, Krzysztof J. Bolstered eIF4E-dependent mRNA translation in patients with Autism 266 Spectrum Disorder

Takada, Hiraku TGS and Helical domains are crucial for tRNA-dependent locking of Rel 267 on the ribosome to drive processive (p)ppGpp synthesis

Tamm, Tiina Protein domains responsible for evolutionary success of eukaryotic 268 ribosomes

Tchorzewski, Marek Presenter: Grela, Przemyslaw Mode of interaction of ribosomal stalk proteins with translational factors 269

Thoms, Sven Functional translational readthrough 270

Ting, Michael uORF mediated translational regulation of the plant circadian clock 271

Turnbull, Kathryn Structural basis for ribosomal protection by the Listeria monocytogenes 272 ABCF ATPase Lmo0919

Vadivel Gnanasundram, Sivakumar HDM2 regulates E2F1 synthesis upon EBNA1 induced mRNA 273 translation stress.

Valadon, Charlène Importance of RNA modifications on translational regulations 274

Page 38 Posters A-Z van der Horst, Sjors Novel pipeline identifies new uORFs and non-AUG main ORFs using 275 sequence conservation

Vanselow, Sven Stepwise assembly of eIF2 by the ATP-Grasp protein Cdc123 276

Vieira, Carlos Regulatory roles of SERBP1 Ser330 phosphorylation identified by 277 funSILAC – an unbiased proteome-wide functional screening for protein post-translationally modified sites

Vincent, Theresa Presenter: Blanchard, Scott C. Ribosome biogenesis during cell cycle arrest fuels EMT in development 278 and disease

Voigt, Franka Quantifying gene expression noise via single mRNA imaging in living 279 cells

Waldron, Joseph Global mRNA Structure-Seq yields insights into the helicase activity of 280 eIF4A during translation initiation

Wallace, Edward context controls translation initiation in the fungal kingdom 281

Wang, Jia The role of mRNA looping in regulating translational initiation efficiency 282

Wang, Zefeng Pervasive translation of circular RNAs driven by short IRES-like 283 elements

Weigand, Julia E. Muscleblind-like 2 controls the hypoxia response of cancer cells 284

Wells, Jennifer Protection factors Lso2, CCDC124 and EBP1 bound to yeast and 285 human 80S ribosomes

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Wethmar, Klaus Somatic mutations alter canonical and alternative upstream translational 286 initiation and termination codons in acute myeloid leukemia

Wieden, Hans-Joachim One design to guide them all: High Resolution structure and 287 biochemical characterization of the conserved ATPase YchF bound to the Plasmodium falciparum ribosome

Willmer, Moritz W. R. Ribosome recycling in a natural translation termination context 288

Wohlgemuth, Ingo induce miscoding clusters in cellular proteins 289

Woodvine, Bethany Reprogramming translation in mammalian cells by tRNA pool 290 modifications

Xu, Fu SSD1 suppresses phenotypes induced by the lack of 291 Elongator-dependent tRNA modifications

Yamashita, Yui In vivo status of S-adenosyl-L-methionine-induced translation arrest on 292 Arabidopsis CGS1 mRNA

Yan, Shuling Slam RNA localization and translation are regulated by FMRP in early 293 Drosophila embryos

Yang, Yun Global identification of cap-independent translation initiation sites in 294 human transcriptome

Yang-Yen, Hsin-Fang TCTP promotes mRNA translation during T cell activation 295

Yi, Sung-Hui Reconstitution of human translation initiation system 296

Page 40 Posters A-Z

Yordanova, Martina Translation of a conserved ORF in the AMD1 3’ trailer: exploring the 297 effects on initiation

Young, David Presenter: Guydosh, Nicholas Recycling of 40S ribosomes and translation of ORFs internal to coding 298 sequences revealed by small-subunit ribosome profiling

Young-Baird, Sara Suppression of a MEHMO syndrome mutation in eIF2 by small molecule 299 ISRIB

Zaher, Hani The ribosome and quality control of chemically-damaged mRNA 300

Zeman, Jakub eIF3: A Structural Odyssey. An epic drama of exploring the yeast eIF3 301 structure

Zemella, Anne Site-specific modification of erythropoietin produced in cell-free extracts 302

Zhang, Yujie High-throughput 5PSeq for ribosome dynamics analysis 303

Zheng, Alice Studies on EBNA1 and its GAr domain shed light on a novel translation 304 control pathway

Zhou, Fujun mRNA Recruitment Sequencing (RecSeq), a deep-sequencing based 305 high-throughput approach for studying mRNA recruitment by 43S PICs in vitro

Zinshteyn, Boris Identification of factors that suppress protein output from a 306 splicing-independent NMD reporter

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Zuccotti, Alessandro Eukaryotic Elongation Factor 2 kinase, activated in the response to 307 ribosomal stress, is a novel target of the oncogenic PIM1 kinase

Zuidhof, Hidde R. Translational regulation and oncogenic functions of C/EBPß-LIP in 308 breast cancer

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