Jubilee Supplement50 a History of ESPGHAN and Its Contributions to Paediatric Gastroenterology, Hepatology and Nutrition

Total Page:16

File Type:pdf, Size:1020Kb

Jubilee Supplement50 a History of ESPGHAN and Its Contributions to Paediatric Gastroenterology, Hepatology and Nutrition ESPGHAN 1968 – 2018 Celebrating Years Jubilee Supplement50 A History of ESPGHAN and its Contributions to Paediatric Gastroenterology, Hepatology and Nutrition Guest Editor Lawrence Weaver School of Medicine and Centre for the History of Medicine, University of Glasgow, Glasgow, Scotland, UK ESPGHAN Council 2018 and office staff from left to right are as follows: Kevin McCluskey – ESPGHAN Office, Iva Hojsak, Nicolette Moes, Katharina Ikrath – ESPGHAN Office, Christian Almuthe Hauer, Piotr Socha, Mary Fewtrell, Sarah Caillet – ESPGHAN Office, Raanan Shamir, Tena Niseteo, Annamaria Staiano, Gigi Veereman, Dominique Belli, Henkjan Verkade, Nikhil Thapar ESPGHAN Council President Raanan Shamir General Secretary Gigi Veereman Treasurer Annamaria Staiano Education Secretary Iva Hojsak International Affairs Rep. Christina A. Hauer Scientific Secretary Piotr Socha Chair of Gastroenterology Committee Nikhil Thapar Chair of Hepatology Committee Henkjan Verkade Chair of Nutrition Committee Mary Fewtrell Chair of Local Organising Committee Dominique Belli Chair of Young ESPGHAN Committee Nicolette Moes Chair of Allied Health Professionals Committee Tena Niseteo JPGN JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION A Journal of Clinical, Experimental, and Developmental Investigation in Pediatric Gastroenterology, Hepatology, and Nutrition www.jpgn.org The Official Journal of ESPGHAN 1968 – 2018 Celebrating Fifty Years Jubilee Supplement A History of ESPGHAN and its Contributions to Paediatric Gastroenterology, Hepatology and Nutrition Guest Editor Lawrence Weaver School of Medicine and Centre for the History of Medicine, University of Glasgow, Glasgow, Scotland, UK Editorial Committee and Co-Editors Michael Lentze Department of Paediatrics, University Hospitals, Bonn, Germany Berthold Koletzko Ludwig-Maximilians-Universität Munich, Dr von Hauner Children’s Hospital, University of Munich Medical Center, München, Germany Olivier Goulet Division of Pediatric Gastroenterology-Hepatology-Nutrition, Hôpital Necker Enfants Malades, University Paris Descartes, Paris, France Martin Burdelski Universitäts-Kinderklinik Hamburg-Eppendorf, Hamburg, Germany Olle Hernell Department of Clinical Sciences/Pediatrics, Umeå University, Umeå, Sweden Hania Szajewska Department of Paediatrics, The Medical University of Warsaw, Warsaw, Poland Dominique Belli Département Enfant et Adolescent, Service Pédiatrie Générale, Université de Genève, Switzerland JPGN Journal of Pediatric Gastroenterology and Nutrition Volume 66 The Official Journal of European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and Supplement 1 the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition April 2018 Table of Contents S1 Introduction Lawrence T. Weaver S2 Chapter 1. The Historical Roots of Paediatric Gastroenterology, Hepatology, and Nutrition Lawrence T. Weaver S20 Chapter 2. ESPGHAN: 50 Years Memories—The Early Years Michael J. Lentze, Salvatore Auricchio, Samy Cadranel, Peter J. Milla, Deirdre Kelly, Alexander S. McNeish, Jean Rey, Jacques Schmitz, Birgitta Strandvik, Jan Taminiau, and Jarmo Visakorpi S29 Chapter 3. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition in Recent Years Berthold Koletzko, Raanan Shamir, Ilse Broekaert, and Riccardo Troncone S44 Chapter 4. The Relationship Between the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition Carlos H. Lifschitz, Jon Vanderhoof, Harland Winter, Stefano Guandalini, William Klish, Richard Grand, Allan Walker, and Jay Perman S54 Chapter 5. Fifty Years of Paediatric Gastroenterology Olivier Goulet, Ricardo Troncone, Marku Makki, Jacques Schmitz, Isabel Polanco, Maria Luisa Mearin, Samy Cadranel, Sibylle Koletzko, Giuseppina Oderda, Alan Phillips, Simon Murch, John Walker-Smith, Frank Ruemmele, Jorge-Amil Dias, Sanja Kolacek, Yigael Finkel, John Puntis, Antonella Diamanti, Susan Hill, Florence Lacaille, Girish Gupte, Jean Francois Mougenot, Mike Thompson, Marc Benninga, Nikhil Thapar, Annamaria Staiano, Gigi Veereman, Yvan Vandenplas, Peter Milla, Jehan-François Desjeux, Alfredo Guarino, and Hania Szajewska S116 Chapter 6. ESPGHAN’s Contributions to Paediatric Hepatology Martin Burdelski, Etienne Sokal, Pilar Nannini, Anil Dhawan, Giorgina Mieli-Vergani, Diego Vergani, Nedim Hadzic, Giussepe Maggiore, Pietro Vajro, Giulia Paolella, Giovanna Alfano, Roderick Houwen, and Deirdre Kelly S144 Chapter 7. The Contributions of the ESPGHAN Committees on Nutrition to Paediatric Nutrition Olle Hernell, Peter Aggett, Mary Fewtrell, Berthold Koletzko, and Jean Rey S154 Chapter 8. 50 Years of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN): Captivating Witness Reports of a Success Story Salvatore Auricchio, Samy Cadranel, Stefano Guandalini, Deirdre Kelly, Berthold Koletzko, Michael J. Lentze, Alexander S. McNeish, Peter J. Milla, Jean Rey, Jacques Schmitz, Raanan Shamir, Birgitta Strandvik, Riccardo Troncone, and Jarmo Visakorpi S172 Chapter 9. Words From Partner Societies Barbara Golden, Tom Stiris, Julián Panés, Leyla Namazova-Baranova, André Van Gossum, Heiner Boeing, Zulfiqar A. Bhutta, Armando Madrazo, James E. Heubi, Nezha Mouane, Paul Fockens, and Berthold Koletzko Listed in Index Medicus/Medline, Current Contents/Clinical Medicine/Life Science, Excerpta Medica, Biosis, PASCAL/CNRS, and the Combined Health Information Data- base/NIDDK. Articles and issue photocopies and 16mm microfilm, 35 mm microfilm, and 105 mm microfiche are available from University Microfilms International (UMI), 300 North Zeeb Road, Ann Arbor, MI 48106-1346, U.S.A. Journal of Pediatric Gastroenterology and Nutrition (ISSN 0277-2116) is published monthly in two volumes per year by Wolters Kluwer Health, Inc., at 14700 Citicorp Drive, Bldg 3, Hagerstown, MD 21742. Business offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Periodicals postage paid at Hagerstown, MD and at additional mailing offices. Copyright © 2018 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. Annual Subscription Rates: United States--$944 Individual, $2364 Institution, $466 In-training. Rest of World--$944 Individual, $2681 Institution, $466 In-training. Single copy rate $224. All prices include a handling charge. Subscriptions outside of North America must add $29 for airfreight delivery. United States residents of Al, CO, DC, FL, GA, HI, IA, ID, IN, KS, KY, LA, MD, MO, ND, NM, NV, PR, RI, SC, SD, UT, VT, WA, WV add state sales tax. The GST tax of 7% must be added to all orders shipped to Canada (Wolters Kluwer Health, Inc.’s GST Identification #895524239, Publications Mail Agreement #40052291). Subscription prices outside the United States must be pre- paid. Prices subject to change without notice. Visit us online at www.lww.com. Address for non-member subscription information, orders, or change of address: Wolters Kluwer Health, Inc., P.O. Box 1610, Hagerstown, MD 21740; phone 800-638- 3030 (outside the United States 301-223-2300; fax 301-223-2400). In Japan, contact LWW Igaku-Shoin Ltd., 3-23-14 Hongo, Bunkyo-ku, Tokyo 113-0033; phone 81-3-5689- 5400; fax 81-3-5689-5402. Postmaster: Send address changes to Journal of Pediatric Gastroenterology and Nutrition, P.O. Box 1610, Hagerstown, MD 21740. Wolters Kluwer Health, Inc. cannot be held responsible for errors or for any consequences arising from the use of the information contained in this journal. The appearance of advertising in this journal does not constitute an endorsement or approval by Wolters Kluwer Health, Inc. of the quality or value of the product advertised or of the claims made for it by its manufacturer. When citing this journal, abbreviate as J Pediatr Gastroenterol Nutr. Permission to reproduce copies of articles for noncommercial use may be obtained from the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923; (978) 750-8400, FAX: (978) 750-4470, www.copyright.com. SUPPLEMENT Introduction Lawrence T. Weaver n 2014 I was asked by the President and Council of ESPGHAN pathophysiology and underlying genetic and environmental causes. to convene a small group of members to put together a ‘‘History ESPGHAN has played a significant part in the birth of paediatric ofI ESPGHAN’’ to mark its 50th anniversary. This is the result—a hepatology as a distinct branch of paediatrics, and Chapter 6 supplement that aims to give an account of the origins and founda- addresses some common diseases of the liver, the understanding tion of the Society, to record its activities, to celebrate its achieve- of which, through the collaborative efforts of members of ESP- ments, and to highlight its significant contributions to paediatric GHAN, have been central to this process. Chapter 7 explores the gastroenterology, hepatology, and nutrition (PGHAN). interface of paediatric gastroenterology and nutrition and how, from Growing from a meeting in 1968 of fewer than 40 people, it is the founding of ESPGHAN, interest in the nutrition of the newborn now an international organisation with hundreds of members, from played a central role in its activities, and its committees of nutrition all European countries and some further afield, committed to the became influential in European affairs in formulating guidelines for practice of PGHAN. The history of PGHAN and the history of feeding infants as well as defining nutritional requirements
Recommended publications
  • Abstracts from the 9Th Biennial Scientific Meeting of The
    International Journal of Pediatric Endocrinology 2017, 2017(Suppl 1):15 DOI 10.1186/s13633-017-0054-x MEETING ABSTRACTS Open Access Abstracts from the 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society (APPES) and the 50th Annual Meeting of the Japanese Society for Pediatric Endocrinology (JSPE) Tokyo, Japan. 17-20 November 2016 Published: 28 Dec 2017 PS1 Heritable forms of primary bone fragility in children typically lead to Fat fate and disease - from science to global policy a clinical diagnosis of either osteogenesis imperfecta (OI) or juvenile Peter Gluckman osteoporosis (JO). OI is usually caused by dominant mutations affect- Office of Chief Science Advsor to the Prime Minister ing one of the two genes that code for two collagen type I, but a re- International Journal of Pediatric Endocrinology 2017, 2017(Suppl 1):PS1 cessive form of OI is present in 5-10% of individuals with a clinical diagnosis of OI. Most of the involved genes code for proteins that Attempts to deal with the obesity epidemic based solely on adult be- play a role in the processing of collagen type I protein (BMP1, havioural change have been rather disappointing. Indeed the evidence CREB3L1, CRTAP, LEPRE1, P4HB, PPIB, FKBP10, PLOD2, SERPINF1, that biological, developmental and contextual factors are operating SERPINH1, SEC24D, SPARC, from the earliest stages in development and indeed across generations TMEM38B), or interfere with osteoblast function (SP7, WNT1). Specific is compelling. The marked individual differences in the sensitivity to the phenotypes are caused by mutations in SERPINF1 (recessive OI type obesogenic environment need to be understood at both the individual VI), P4HB (Cole-Carpenter syndrome) and SEC24D (‘Cole-Carpenter and population level.
    [Show full text]
  • Dec1 Untitled REF GUIDE FINAL[2]
    UNTITLED RESOURCE GUIDE SUGGESTIONS FOR ENGAGEMENT ABOUT UNTITLED Beginning with a reflection on the early AIDS epidemic, Untitled eschews a linear narrative to introduce a fractious timeline, moving from the sublime to the tragic and back again. By juxtaposing mainstream network news, activist footage, artists' work, and popular entertainment from the last turbulent decades, Untitled references regimes of power that precipitated a generation of AIDS and queer activism and continues today with international struggle and expression. In 2010, artist Jim Hodges was invited to give a lecture on the billboard project of Félix González-Torres at San Antonioʼs Artpace. He teamed up with fellow filmmakers Carlos Marques da Cruz and Encke King to create Untitled. Neither a portrait or a documentary about González- Torres, the film was an attempt to place the viewer “in his room,” that is to say, the filmmakers worked to create, for the viewer, an understanding of the influences and contexts within which González- UNTITLED Torres was working. In Hodges's words, “In this way, the framing of the artist can become a way to project any number of people, endlessly.” A Film by Untitled can therefore be considered to be as much about González- Jim Hodges, Carlos Marques da Cruz, and Encke King Torres and the AIDS crisis as it can be seen as grappling with the continuum of global dehumanization. PURPOSE OF THIS RESOURCE GUIDE In an effort to honor the sense of endlessness that Untitled suggests, this guide is a resource for provoking both public and private conversation. We have provided you with: • WORDS for engagement regarding HIV/AIDS, art, and culture • THOUGHTS to provoke dialogue • HIV/AIDS TIMELINE • INFORMATION about prevention and wellness • LINKS to extend the conversation CREDITS • Like the film, this Resource Guide hopes to raise more questions than it answers.
    [Show full text]
  • Curbing Unfair Drug Prices: a Primer for States by the Global Health Justice Partnership Is Licensed Under a Creative Commons Attribution 3.0 Unported License
    Curbing Unfair Drug Prices ________________________________________________ A Primer for States Global Health Justice Partnership Policy Paper August 2017 Global Health Justice Partnership of the Yale Law School and the Yale School of Public Health National Physicians Alliance Universal Health Care Foundation of Connecticut Lead Authors: Aaron Berman, Yale School of Public Health, 2017 Theodore Lee, Yale Law School, 2018 Adam Pan, Yale Law School, 2019 Zain Rizvi, Yale Law School, 2017 Arielle Thomas, Yale School of Public Health, 2017 Curbing Unfair Drug Prices: A Primer for States by the Global Health Justice Partnership is licensed under a Creative Commons Attribution 3.0 Unported License. It may be freely reproduced, as long as it is correctly attributed. Yale Global Health Justice Partnership Yale Global Health Justice Partnership The Yale Global Health Justice Partnership (GHJP) is a joint initiative between Yale Law School (YLS) and Yale School of Public Health (YSPH) that trains the next generation of scholars and practitioners to tackle the complex interdisciplinary challenges of global health. The GHJP works with international partners at the interface of law and governance, public health, and medicine to theorize, build analytical frameworks, create knowledge, and mobilize research to help drive the social change necessary for improving the health and wellness of people around the world. Learn more at www.yaleghjp.org. The GHJP offers a practicum course each year that engages students in real-world projects with scholars, activists, lawyers, and other practitioners on issues of health justice. Working papers are produced as a part of these projects, with students as lead authors. Final papers reflect input and revisions by GHJP faculty, partners, staff, and other readers.
    [Show full text]
  • Big Pharma Takes It
    A Public Eye Report – March 2021 Big Pharma takes it all How pharmaceutical corporations profiteer from their privileges – even in a global health crisis like COVID-19 1 COVID-19, SHOWCASE OF A PERVERTED BUSINESS MODEL 3 2 BIG PHARMA’S 10 STRATEGIES FOR CASHING IN 7 2.1 – Determine R & D priorities by potential profits alone 9 2.2 – Abuse patents to lock up knowledge, inflate prices and limit supply 10 2.3 – Direct the system towards the needs of high-income countries 13 2.4 – Avoid public accountability 16 2.5 – Design clinical trials for self-interest 18 2.6 – Socialise risks, privatise profits 20 2.7 – Embrace public investment, reject public returns 22 2.8 – Impose unjustifiable, unchallengeable prices 24 2.9 – Financialise innovation 29 2.10 – Lobby pervasively 31 3 SWITZERLAND IS ‘PHARMALAND’ 33 4 CONCLUSION: WHAT COVID-19 SHOWS US 37 5 TIME TO ACT: OUR DEMANDS 39 Endnotes 42 IMPRINT Big Pharma takes it all: How pharmaceutical corporations profiteer from their privileges – even in a global health crisis like COVID-19. A Public Eye Report, March 2021, 52 pages. | Authors Patrick Durisch, Gabriela Hertig | Contributors Christa Luginbühl, Oliver Classen | Edition Mary Louise Rapaud | Publishers Romeo Regenass, Ariane Bahri | Layout Karin Hutter, karinhutter.com | Icons opak.cc | Cover picture © Tang Ming Tung/Getty Images PUBLIC EYE Dienerstrasse 12, Postfach, CH-8021 Zurich | +41 (0)44 2 777 999 | [email protected] Avenue Charles-Dickens 4, CH-1006 Lausanne | +41 (0)21 620 03 03 | [email protected] Donations IBAN CH64 0900 0000 1001 0813 5, Public Eye | publiceye.ch 1 ��-19, showcase of a perverted business model Monty Rakusen/Keystone © 4 BIG PHARMA TAKES IT ALL “No one is safe until everybody is safe”, “leave no one behind” are mantras that have been oft repeated by state leaders and the World Health Organization (WHO) since the coronavirus pandemic turned our world upside down in spring, 2020.
    [Show full text]
  • Technology to Enable the Clinical Genomics Revolution
    Technology to Enable the Clinical Genomics Revolution Session 100, February 13, 2019 Kate Birch, Data & Technology Program Manager, Melbourne Genomics Health Alliance and CSIRO 1 Conflict of Interest Kate Birch, BSc(Hons) MIS CHIA, has no real or apparent conflicts of interest to report. 2 Agenda • From clinical genetics to clinical genomics • Melbourne Genomics Health Alliance • In clinical practice, is genomics better than standard care? • Technology to enable genomics • Patients views on data sharing 3 Learning Objectives • Recognize the need for whole-of-system change in the implementation of clinical genomics • Demonstrate evidence for the utility and economics of genomics as a front line test • Distinguish the different requirements for the implementation of technology in emerging versus established areas of clinical practice • Contrast the differences in data sharing preferences and concerns between patient populations and well populations 4 From genetics to genomics • Genetics scrutinizes the functioning and composition of the single gene where as • Genomics addresses all genes and their inter relationships in order to identify their combined influence on the growth and development of the organism World Health Organisation 5 Cost of sequencing a human genome 6 Phimister et al., NEJM 366: 757-9, 2012 From genetics to genomics Integration with microbiome, proteomics, metaboloimics... Whole genome Whole exome Large panels Small panels Single gene 7 From genetics to genomics Integration with microbiome, proteomics, metaboloimics..
    [Show full text]
  • Chronik UNIKATE 10/Korr
    92 ESSENER UNIKATE 10/1998 93 Seit den ersten Legendenberichten von Jacob von Voragine, dem Erzbischof von Genua, der bereits im 13. Jahrhundert von der Verpflanzung eines Beines durch die Heiligen Cosmas und Damian berichtete, bewegte der Gedanke an die Möglichkeit einer Transplantation das christliche Abendland immer wieder. Lange blieben diese Vorstellungen im Bereich von Mythen und Utopien, bis die Medizin und die mit ihr verbundenen Wissenschaften seit Anfang dieses Jahrhunderts die Utopie Stück für Stück Realität werden ließen. Die Entwicklung der modernen Transplantationsmedizin Eine Chronik Zusammengestellt von Norbert Weigend und Hans-Reinhard Zerkowski* technik scheitern Jaboulays Versu- 1900 che ebenso wie die experimentellen In Wien entdeckt Karl Landsteiner Transplantationen Ernst Ungers um das erste menschliche Blutgruppen- 1909 am Rudolf-Virchow-Kranken- system (A-B-0) und ermöglicht da- haus in Berlin. mit Bluttransfusionen, eine erste Form der Organ-Transplantation. 1908 Alexis Carrel, 1904 in die USA nach 1902 Chicago ausgewandert und seit 1906 Am 7. März 1902 berichtet Privat- am Rockefeller Institute in New dozent Dr. Emerich Ullmann in der York, perfektioniert zusammen mit Sitzung der Wiener Ärztegesell- Charles-Claude Guthrie die Gefäß- schaft von einer ersten technisch Der erste Bericht über eine experimentelle Nierentransplantation, die Emerich gelungenen Nie- Ullmann am 7. März 1902 durchführte rentransplantation an einem Hund. gen notiert er: „Heute eine chirur- Im selben Jahr gisch-technische Kuriosität, könnten beschreibt auch Transplantationen ... eines Tages Alexis Carrel in praktisches Interesse haben.“ Emerich Ullmann der französischen Fachpublikation „Lyon Médical“ 1906 Die Verbindung von Blutgefäßen nach einer ein vergleichbares Experiment. Als Zeichnung von A. Carrel, 1902 erster Chirurg verbindet er Blutge- Mathieu Jaboulay, Carrels Lehrer fäße mit feiner Seide durch eine ein- am Krankenhaus Hôtel-Dieu in naht.
    [Show full text]
  • Gulf Women's Successes Highlighted at Conference
    SUBSCRIPTION MONDAY, DECEMBER 1, 2014 SAFAR 9, 1436 AH www.kuwaittimes.net Gulf women’s Acquitted Mourners Saudi spitter successes US couple celebrate life named AFC highlighted at banned from of Lebanese player of conference3 leaving7 Qatar diva40 Sabah the20 year Kuwait, Gulf stocks hit Min 06º Max 19º hard over OPEC decision High Tide 05:57 & 19:29 Oil plunge triggers panic selling MPs slam govt inaction Low Tide • 00:25 & 12:52 40 PAGES NO: 16359 150 FILS By B Izzak and Agencies Another MP KUWAIT: Gulf Arab stocks plunged yesterday on their first trading day since OPEC decided to maintain oil out- blasts India put in a move that sent crude prices crashing to five-year lows, analysts said. All seven bourses in the energy-rich guarantee Gulf Cooperation Council (GCC) had been closed for the Friday-Saturday weekend following OPEC’s decision late By B Izzak Thursday. Kuwait Stock Exchange price index dipped 3.3 percent to close at 6,754.60 points, the lowest level since KUWAIT: Another Kuwaiti lawmaker yesterday called on March 2013. The weighted index shed 5.9 percent. the Kuwaiti government to react to an Indian decision A number of MPs yesterday criticized the govern- requiring a $2,500 bank guarantee for each domestic ment’s inaction towards the Kuwait Stock Exchange. MP worker, saying that some of the measures should include Abdullah Al-Maayouf said the government is a spectator halting recruitment of manpower from the Asian giant. MP to the collapse of the bourse and the real estate and Faisal Al-Kandari, the second National Assembly member investment sectors.
    [Show full text]
  • Supplementary Table S4. FGA Co-Expressed Gene List in LUAD
    Supplementary Table S4. FGA co-expressed gene list in LUAD tumors Symbol R Locus Description FGG 0.919 4q28 fibrinogen gamma chain FGL1 0.635 8p22 fibrinogen-like 1 SLC7A2 0.536 8p22 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 DUSP4 0.521 8p12-p11 dual specificity phosphatase 4 HAL 0.51 12q22-q24.1histidine ammonia-lyase PDE4D 0.499 5q12 phosphodiesterase 4D, cAMP-specific FURIN 0.497 15q26.1 furin (paired basic amino acid cleaving enzyme) CPS1 0.49 2q35 carbamoyl-phosphate synthase 1, mitochondrial TESC 0.478 12q24.22 tescalcin INHA 0.465 2q35 inhibin, alpha S100P 0.461 4p16 S100 calcium binding protein P VPS37A 0.447 8p22 vacuolar protein sorting 37 homolog A (S. cerevisiae) SLC16A14 0.447 2q36.3 solute carrier family 16, member 14 PPARGC1A 0.443 4p15.1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha SIK1 0.435 21q22.3 salt-inducible kinase 1 IRS2 0.434 13q34 insulin receptor substrate 2 RND1 0.433 12q12 Rho family GTPase 1 HGD 0.433 3q13.33 homogentisate 1,2-dioxygenase PTP4A1 0.432 6q12 protein tyrosine phosphatase type IVA, member 1 C8orf4 0.428 8p11.2 chromosome 8 open reading frame 4 DDC 0.427 7p12.2 dopa decarboxylase (aromatic L-amino acid decarboxylase) TACC2 0.427 10q26 transforming, acidic coiled-coil containing protein 2 MUC13 0.422 3q21.2 mucin 13, cell surface associated C5 0.412 9q33-q34 complement component 5 NR4A2 0.412 2q22-q23 nuclear receptor subfamily 4, group A, member 2 EYS 0.411 6q12 eyes shut homolog (Drosophila) GPX2 0.406 14q24.1 glutathione peroxidase
    [Show full text]
  • 125 Years of Women in Medicine
    STRENGTH of MIND 125 Years of Women in Medicine Medical History Museum, University of Melbourne Kathleen Roberts Marjorie Thompson Margaret Ruth Sandland Muriel Denise Sturtevant Mary Jocelyn Gorman Fiona Kathleen Judd Ruth Geraldine Vine Arlene Chan Lilian Mary Johnstone Veda Margaret Chang Marli Ann Watt Jennifer Maree Wheelahan Min-Xia Wang Mary Louise Loughnan Alexandra Sophie Clinch Kate Suzannah Stone Bronwyn Melissa Dunbar King Nicole Claire Robins-Browne Davorka Anna Hemetek MaiAnh Hoang Nguyen Elissa Stafford Trisha Michelle Prentice Elizabeth Anne McCarthy Fay Audrey Elizabeth Williams Stephanie Lorraine Tasker Joyce Ellen Taylor Wendy Anne Hayes Veronika Marie Kirchner Jillian Louise Webster Catherine Seut Yhoke Choong Eva Kipen Sew Kee Chang Merryn Lee Wild Guineva Joan Protheroe Wilson Tamara Gitanjali Weerasinghe Shiau Tween Low Pieta Louise Collins Lin-Lin Su Bee Ngo Lau Katherine Adele Scott Man Yuk Ho Minh Ha Nguyen Alexandra Stanislavsky Sally Lynette Quill Ellisa Ann McFarlane Helen Wodak Julia Taub 1971 Mary Louise Holland Daina Jolanta Kirkland Judith Mary Williams Monica Esther Cooper Sara Kremer Min Li Chong Debra Anne Wilson Anita Estelle Wluka Julie Nayleen Whitehead Helen Maroulis Megan Ann Cooney Jane Rosita Tam Cynthia Siu Wai Lau Christine Sierakowski Ingrid Ruth Horner Gaurie Palnitkar Kate Amanda Stanton Nomathemba Raphaka Sarah Louise McGuinness Mary Elizabeth Xipell Elizabeth Ann Tomlinson Adrienne Ila Elizabeth Anderson Anne Margeret Howard Esther Maria Langenegger Jean Lee Woo Debra Anne Crouch Shanti
    [Show full text]
  • Random Coefficient Repeated Measures Models
    (Entry for Encyclopaedia of Biostatistics, Armitage, P., & Colton,T. (Eds.), 1998, Wiley.) Random coefficient repeated measures models by Harvey Goldstein Institute of Education London, WC1H 0AL [email protected] Introduction This section is concerned with modelling data where measurements of one or more attributes are repeated on the same set of individuals over time. Typical applications are to the modelling of anthropometric growth of children or animals. The model specification will be developed for the case where a single continuous measurement is made on several occasions for a sample. This will then be extended to consider the case of multiple measurements at each time point and mention will be made of extensions to latent variable models and to discrete response data. To begin with we look at the simple, restricted, data structure where there are a fixed number of measurement occasions and each individual has a measurement at each occasion. Multivariate models Consider the data matrix of responses Individual Occasion 1 Occasion 2 Occasion 3 Occasion 4 1 y11 y21 y31 y41 2 y12 y22 y32 y42 3 y13 y23 y33 y43 The first subscript refers to occasion and the second to individual. We assume multivariate normality and so for the response vector we have initially YN~(,)µ Σ (1) This constitutes a null model and in general we will wish to include further variables, notably age or time. Suppose we wish to express the response, say a weight measurement, as a linear function of time (t) measured at each occasion. We may then write =+β β +ε ytij01 j j ij ij (2) where we allow the intercept and average growth rate to vary across individuals.
    [Show full text]
  • Program for Gastroenterology and Clinical Nutrition at the Royal Children’S Hospital, Melbourne
    PROGRAM FOR GASTROENTEROLOGY AND CLINICAL NUTRITION AT THE ROYAL CHILDREN’S HOSPITAL, MELBOURNE The Department Our department provides tertiary and quaternary services to the states of Victoria, Tasmania and South Australia in the areas of liver disease and transplantation. We are establishing the only national program in intestinal failure and intestinal transplant services [Professor Hardikar and Professor Bines]. Many in the department are leaders in the fields of transplant medicine, inflammatory bowel disease and pancreatic disorders. A full array of diagnostic and therapeutic procedures are performed on site and this also includes a state of the art diagnostic laboratory for motility studies. The Department of Gastroenterology and Clinical Nutrition has a rich history with “Rotavirus” being discovered by Professor Ruth Bishop at the Royal Children’s Hospital. The work of Professor Graeme Barnes and Dr Rudge Townley should be acknowledged in the build up to this important discovery. In addition to this the work of Professor Charlotte Anderson should be highlighted as she provided substantial insights into cystic fibrosis and coeliac disease. The Training Program Aims of the Program 1) To provide a framework of knowledge in the basic sciences and clinical practice of gastroenterology, hepatology and clinical nutrition. 2) To provide experience in gastroenterological procedures commonly used in clinical practice (endoscopy, percutaneous endoscopically placed gastrostomy, oesophageal pH monitoring, gastrointestinal motility and breath testing). 3) To encourage and facilitate research within the fields of luminal gastroenterology, hepatology, transplantation (intestinal and liver) and nutrition. 4) To help provide an education for each trainee which is appropriate for their future practice. The purpose of the 12 month positions is to provide training for physicians wishing to specialise in paediatric gastroenterology.
    [Show full text]
  • Environmental Pollution in Urban Environments and Human Biology
    7 Aug 2003 8:27 AR AR196-AN32-06.tex AR196-AN32-06.sgm LaTeX2e(2002/01/18) P1: IKH 10.1146/annurev.anthro.32.061002.093218 Annu. Rev. Anthropol. 2003. 32:111–34 doi: 10.1146/annurev.anthro.32.061002.093218 Copyright c 2003 by Annual Reviews. All rights reserved First published online as a Review in Advance on June 4, 2003 ENVIRONMENTAL POLLUTION IN URBAN ENVIRONMENTS AND HUMAN BIOLOGY Lawrence M. Schell and Melinda Denham Department of Anthropology, University at Albany, State University of New York, 1400 Washington Ave., Albany, New York, 12222; email: [email protected], [email protected] Key Words growth, lead, noise, stress, urbanism ■ Abstract The biocultural approach of anthropologists is well suited to understand the interrelationship of urbanism and human biology. Urbanism is a social construction that has continuously changed and presented novel adaptive challenges to its residents. Urban living today involves several biological challenges, of which one is pollution. Using three different types of pollutants as examples, air pollution, lead, and noise, the impact of pollution on human biology (mortality, morbidity, reproduction, and develop- ment) can be seen. Chronic exposure to low levels of these pollutants has a small impact on the individual, but so many people are exposed to pollution that the effect species- wide is substantial. Also, disproportionate pollutant exposure by socioeconomically disadvantaged groups exacerbates risk of poor health and well being. URBANISM AND HUMAN BIOLOGY Urban growth began slowly several thousand years ago and has accelerated tremen- dously over the past 300 years. By 2006, half of the world’s population will be living in urban places (United Nations 1998).
    [Show full text]