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a person of any nationality to have beta trait. trait. thalassemia beta have to nationality any of person a

Asia, the , or the Mediterranean region. It is possible for for possible is It region. Mediterranean the or East, Middle the Asia, ,

Hematology

Beta thalassemia trait is common in people whose ancestors came from from came ancestors whose people in common is trait thalassemia Beta

Who can have trait? trait? thalassemia beta have can Who

disease or later in life. life. in later disease cell sickle or disease

Trait Trait People with beta thalassemia trait do not develop beta thalassemia thalassemia beta develop not do trait thalassemia beta with People

People with beta thalassemia do not make enough . hemoglobin. enough make not do thalassemia beta with People

Thalassemia Thalassemia

β ) hemoglobin in their red cells. cells. blood red their in hemoglobin ) ( thalassemia beta abnormal

People with beta thalassemia trait have both normal hemoglobin hemoglobin normal both have trait thalassemia beta with People A and and A

Beta Beta

A. A. hemoglobin type, (1) one

lungs to all parts of your body. People with normal hemoglobin have only only have hemoglobin normal with People body. your of parts all to lungs

Your red blood cells contain hemoglobin, which carries oxygen from the the from oxygen carries which hemoglobin, contain cells blood red Your

FACT SHEET SHEET FACT Beta thalassemia is a condition that affects the red blood cells. cells. blood red the affects that condition a is thalassemia Beta What is beta thalassemia trait? trait? thalassemia beta is What BMC–05/19 (BK600

What if both parents have beta

0) thalassemia trait? If both parents have beta thalassemia trait, there is a 25 percent (1 in 4) chance with each pregnancy of Beta Beta having a child with beta thalassemia . Thalassemia Thalassemia disease Trait Trait The amount of hemoglobin produced determines (Aβ) (Aβ) whether a person has: Beta thalassemia intermedia or Beta thalassemia major disease. Beta thalassemia major is also called Cooley’s .

262 Danny Thomas Place Beta thalassemia disease is a lifelong illness that can Mail Stop 800 cause serious health problems. People with this Beta Beta Beta No Trait Memphis, TN 381 8 705-36 disease need medical treatment. Thalassemia Thalassemia Thalassemia (AA) Disease Trait Trait www or.stjude. g (ββ) (Aβ) (Aβ) Why should I know if I have beta thalassemia trait?

You can pass on beta thalassemia trait to your children, like Beta Thalassemia No Trait you would hair or eye color. Trait (AA) (Aβ) If one (1) parent has beta thalassemia trait and the other parent has normal , there is a 50 percent (1 in 2) chance with each pregnancy of having a child with beta thalassemia trait. Normally, beta thalassemia trait does not cause any health problems. Beta Beta No No Thalassemia Thalassemia Trait Trait Beta thalassemia trait is also known as beta thalassemia minor. Trait Trait (AA) (AA) (Aβ) (Aβ)

What if one (1) parent has beta thalassemia trait and the other parent has ? If one (1) parent has beta thalassemia trait and the other parent has sickle cell trait, there is a 25 percent (1 in 4) chance with each pregnancy of having a child with sickle cell disease. Depending on the amount of hemoglobin produced, this type of sickle cell disease is called:

Sickle beta plus thalassemia or Beta Thalassemia Sickle Cell Trait Trait Sickle beta zero thalassemia disease. (Aβ) (AS) S β hemoglobin A person with sickle cell disease has red blood cells S S β β S β β S β that can sickle or become banana shaped. Under S certain conditions, these cells can keep blood from circulating freely. Sickle cell disease is a lifelong illness that can cause serious health problems. People with this disease need medical treatment. Beta Sickle Sickle Beta No This document is not intended to replace counseling by a trained health care professional or genetic counselor. Questions Thalassemia Cell Thalassemia Trait about personal health concerns or treatment should be discussed with your doctor. For more information about sickle cell disease, visit our Web site at www.stjude.org/sicklecell. Trait Trait Disease (AA) (Aβ) (AS) (Sβ) Funds for reproduction of this document were provided by St. Jude Children’s Research Hospital, ALSAC, and a grant from the Plough Foundation. Copyright © 2009 St. Jude Children’s Research Hospital