Bioactive Natural Compounds and Antioxidant Activity of Essential Oils from Spice Plants: New Findings and Potential Applications
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Redalyc.Géneros De Lamiaceae De México, Diversidad Y Endemismo
Revista Mexicana de Biodiversidad ISSN: 1870-3453 [email protected] Universidad Nacional Autónoma de México México Martínez-Gordillo, Martha; Fragoso-Martínez, Itzi; García-Peña, María del Rosario; Montiel, Oscar Géneros de Lamiaceae de México, diversidad y endemismo Revista Mexicana de Biodiversidad, vol. 84, núm. 1, marzo, 2013, pp. 30-86 Universidad Nacional Autónoma de México Distrito Federal, México Disponible en: http://www.redalyc.org/articulo.oa?id=42526150034 Cómo citar el artículo Número completo Sistema de Información Científica Más información del artículo Red de Revistas Científicas de América Latina, el Caribe, España y Portugal Página de la revista en redalyc.org Proyecto académico sin fines de lucro, desarrollado bajo la iniciativa de acceso abierto Revista Mexicana de Biodiversidad 84: 30-86, 2013 DOI: 10.7550/rmb.30158 Géneros de Lamiaceae de México, diversidad y endemismo Genera of Lamiaceae from Mexico, diversity and endemism Martha Martínez-Gordillo1, Itzi Fragoso-Martínez1, María del Rosario García-Peña2 y Oscar Montiel1 1Herbario de la Facultad de Ciencias, Facultad de Ciencias, Universidad Nacional Autónoma de México. partado postal 70-399, 04510 México, D.F., México. 2Herbario Nacional de México, Instituto de Biología, Universidad Nacional Autónoma de México. Apartado postal 70-367, 04510 México, D.F., México. [email protected] Resumen. La familia Lamiaceae es muy diversa en México y se distribuye con preferencia en las zonas templadas, aunque es posible encontrar géneros como Hyptis y Asterohyptis, que habitan en zonas secas y calientes; es una de las familias más diversas en el país, de la cual no se tenían datos actualizados sobre su diversidad y endemismo. -
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Volume XXXII Number 2 2020 CHIRIOTTI EDITORI ITALIAN JOURNAL OF FOOD SCIENCE (RIVISTA ITALIANA DI SCIENZA DEGLI ALIMENTI) 2nd series Founded By Paolo Fantozzi under the aegis of the University of Perugia Official Journal of the Italian Society of Food Science and Technology Società Italiana di Scienze e Tecnologie Alimentari (S.I.S.T.Al) Initially supported in part by the Italian Research Council (CNR) - Rome - Italy Recognised as a “Journal of High Cultural Level” by the Ministry of Cultural Heritage - Rome - Italy Editor-in-Chief: Paolo Fantozzi - Dipartimento di Scienze Agrarie, Alimentari ed Ambientali, Università di Perugia Via S. Costanzo, I-06126 Perugia, Italy - Tel. +39 075 5857910 - Telefax +39 075 5857939-5857943 e-mail: [email protected] Co-Editors: Chiavaro Emma - Università degli Studi di Parma, e-mail: [email protected] Del Caro Alessandra - Università degli Studi di Sassari - e-mail: [email protected] De Noni Ivano - Università degli Studi di Milano, e-mail: [email protected] Hidalgo Alyssa - Università degli Studi di Milano, e-mail: [email protected] Loizzo Monica Rosa - Università della Calabria, e-mail: [email protected] Rantsiou Kalliopi - Università di Torino, e-mail: [email protected] Rolle Luca Giorgio Carlo - Università degli Studi di Torino, e-mail: [email protected] Vincenzi Simone - Università degli Studi di Padova, e-mail: [email protected] Vittadini Elena Giovanna - Università di Camerino, e-mail: [email protected] Publisher: Alberto Chiriotti - Chiriotti Editori srl, Viale Rimembranza 60, I-10064 Pinerolo, Italy - Tel. +39 0121 393127 - Fax +39 0121 794480 e-mail: [email protected] - URL: www.chiriottieditori.it Aim: The Italian Journal of Food Science is an international journal publishing original, basic and applied papers, reviews, short communications, surveys and opinions on food science and technology with specific reference to the Mediterranean Region. -
Journal of Nephropathology
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by shahrekord university of medical scinces www.nephropathol.com DOI: 10.15171/jnp.2017.25 J Nephropathol. 2017;6(3):144-149 Journal of Nephropathology Ameliorative effect of lycopene effect on cisplatin-induced nephropathy in patients Leila Mahmoodnia, Keivan Mohammadi*, Rohollah Masumi Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran ARTICLE INFO ABSTRACT Article type: Background: Nephrotoxicity is one of the most important limitations of cisplatin-based Original Article chemotherapies which associated with many complications and high mortality rate. Objectives: To investigate the effect of lycopene on cisplatin-induced nephrotoxicity in Article history: patients with cancer. Received: 14 November 2016 Accepted: 2 January 2017 Patients and Methods: In this double-blind, randomized clinical trial, 120 patients were Published online: 17 January 2017 randomly assigned to two groups, case (treated with lycopene + standard regimen of kidney DOI: 10.15171/jnp.2017.25 injury prevention) and control (treated with only the standard regimen of kidney injury prevention). Lycopene was orally taken from 24 hours before to 72 hours after cisplatin Keywords: administration. Blood urea nitrogen (BUN), serum creatinine (Cr), and glomerular Lycopene filtration rate (GFR) were measured and recorded. The data were analyzed using SPSS. Nephrotoxicity Results: Changes in Cr were not significantly different between the two groups (P = 0.131). Cisplatin However, a significant decreasing trend was seen in GFR during the study, which was Cancer more marked in the control group (P = 0.004). BUN significantly decreased during the Original Article study (P = 0.002), and a significant decrease of BUN on the day three in both groups was seen (P = 0.001). -
Optimization of Microwave Assisted Process for Extraction of Celery Seed Essential Oil Gopika Talwari1 and B.S
Gopika Talwari and B.S. Ghuman JAE : 51 (2) Journal of Agricultural Engineering Vol. 51 (2): April-June, 2014 Optimization of Microwave Assisted Process for Extraction of Celery Seed Essential Oil Gopika Talwari1 and B.S. Ghuman2 Manuscript received: March, 2013 Revised manuscript accepted: April, 2014 ABSTRACT Microwave assisted extraction (MAE) method was developed for extraction of essential oil from celery seeds. A domestic microwave oven was modified and Clevenger apparatus attached to it to make it an extraction unit. Effect of various parameters such as soaking time, temperature and power density during MAE was studied. A multivariate study based on a Box-Behnken design was used to evaluate the influence of three major variables (soaking time, temperature and power density) affecting the performance of MAE on celery seed. Oil yield, time of extraction and energy consumption (MJ.kg-1 oil) by MAE were determined and compared with those obtained by the traditional hydro-distillation (HD). It was found that microwave assisted process gave approximately same oil yield (1.90%) in less time ( 93.5 min) and with low energy consumption (58191.78 MJ.kg-1 oil). Results revealed that the selected parameters had significant effect on the responses. Key words: Celery seed, essential oil, microwave assisted extraction, hydro distillation Essential oils are the volatile oils distilled from aromatic an average contains 2.5% volatile oil containing 60-70% plant material. Essential oils are contained in the glands, d-limonene and 1-20% beta selinene and 15%–17% fixed sacs and veins concentrated in different parts of the plant. oil. -
Amplification of Oxidative Stress by a Dual Stimuli-Responsive Hybrid Drug
ARTICLE Received 11 Jul 2014 | Accepted 12 Mar 2015 | Published 20 Apr 2015 DOI: 10.1038/ncomms7907 Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death Joungyoun Noh1, Byeongsu Kwon2, Eunji Han2, Minhyung Park2, Wonseok Yang2, Wooram Cho2, Wooyoung Yoo2, Gilson Khang1,2 & Dongwon Lee1,2 Cancer cells, compared with normal cells, are under oxidative stress associated with the increased generation of reactive oxygen species (ROS) including H2O2 and are also susceptible to further ROS insults. Cancer cells adapt to oxidative stress by upregulating antioxidant systems such as glutathione to counteract the damaging effects of ROS. Therefore, the elevation of oxidative stress preferentially in cancer cells by depleting glutathione or generating ROS is a logical therapeutic strategy for the development of anticancer drugs. Here we report a dual stimuli-responsive hybrid anticancer drug QCA, which can be activated by H2O2 and acidic pH to release glutathione-scavenging quinone methide and ROS-generating cinnamaldehyde, respectively, in cancer cells. Quinone methide and cinnamaldehyde act in a synergistic manner to amplify oxidative stress, leading to preferential killing of cancer cells in vitro and in vivo. We therefore anticipate that QCA has promising potential as an anticancer therapeutic agent. 1 Department of Polymer Á Nano Science and Technology, Polymer Fusion Research Center, Chonbuk National University, Backje-daero 567, Jeonju 561-756, Korea. 2 Department of BIN Convergence Technology, Chonbuk National University, Backje-daero 567, Jeonju 561-756, Korea. Correspondence and requests for materials should be addressed to D.L. (email: [email protected]). NATURE COMMUNICATIONS | 6:6907 | DOI: 10.1038/ncomms7907 | www.nature.com/naturecommunications 1 & 2015 Macmillan Publishers Limited. -
Retention Indices for Frequently Reported Compounds of Plant Essential Oils
Retention Indices for Frequently Reported Compounds of Plant Essential Oils V. I. Babushok,a) P. J. Linstrom, and I. G. Zenkevichb) National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA (Received 1 August 2011; accepted 27 September 2011; published online 29 November 2011) Gas chromatographic retention indices were evaluated for 505 frequently reported plant essential oil components using a large retention index database. Retention data are presented for three types of commonly used stationary phases: dimethyl silicone (nonpolar), dimethyl sili- cone with 5% phenyl groups (slightly polar), and polyethylene glycol (polar) stationary phases. The evaluations are based on the treatment of multiple measurements with the number of data records ranging from about 5 to 800 per compound. Data analysis was limited to temperature programmed conditions. The data reported include the average and median values of retention index with standard deviations and confidence intervals. VC 2011 by the U.S. Secretary of Commerce on behalf of the United States. All rights reserved. [doi:10.1063/1.3653552] Key words: essential oils; gas chromatography; Kova´ts indices; linear indices; retention indices; identification; flavor; olfaction. CONTENTS 1. Introduction The practical applications of plant essential oils are very 1. Introduction................................ 1 diverse. They are used for the production of food, drugs, per- fumes, aromatherapy, and many other applications.1–4 The 2. Retention Indices ........................... 2 need for identification of essential oil components ranges 3. Retention Data Presentation and Discussion . 2 from product quality control to basic research. The identifi- 4. Summary.................................. 45 cation of unknown compounds remains a complex problem, in spite of great progress made in analytical techniques over 5. -
Chemical Composition, Anti-Inflammatory and Antioxidant Activities of the Essential Oil of Piper Cubeba L
Romanian Biotechnological Letters Vol. 22, No. 2, 2017 Copyright © 2017 University of Bucharest Printed in Romania. All rights reserved ORIGINAL PAPER Chemical composition, anti-inflammatory and antioxidant activities of the essential oil of Piper cubeba L. Received for publication, October 8, 2015 Accepted, April 22, 2016 RAMZI A. MOTHANA1,*, MANSOUR S. AL-SAID1, MOHAMMAD RAISH2, JAMAL M. KHALED3, NAIYF S. ALHARBI3, ABDULRAHMAN ALATAR3, AJAZ AHMAD4, MOHAMMED AL-SOHAIBANI5, MOHAMMED AL-YAHYA1, SYED RAFATULLAH1. 1Department of Pharmacognosy and Medicinal, Aromatic & Poisonous Plants Research Center (MAPPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. 2Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. 3Departments of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia 4Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. 5Department of Medicine and Pathology, Gastroenterology Unit, College of Medicine, King Khalid University Hospital, King Saud University, P.O. Box 2925, Riyadh-11461 Saudi Arabia. *Address for correspondence to: [email protected] or [email protected]; Abstract Piper Cubeba (L.) is used as a remedy for various ailments. However, the scientific basis for its medicinal use, especially as anti-inflammation remains unknown. Therefore, the present study aims to investigate the anti-inflammatory and antioxidant activities of Piper cubeba essential oil (PCEO) in laboratory rodent models. The in vivo anti-inflammatory activity of PCEO at three doses (150, 300 and 600 mg /kg, p.o) was tested in carrageenan-induced rat paw edema, cotton pellet granuloma and carrageenan-induced pleurisy. -
Electrophysiological and Behavioral Characterization Of
Deletre et al. Parasites & Vectors (2015) 8:316 DOI 10.1186/s13071-015-0934-y RESEARCH Open Access Electrophysiological and behavioral characterization of bioactive compounds of the Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum and Cinnamomum zeylanicum essential oils against Anopheles gambiae and prospects for their use as bednet treatments Emilie Deletre1* , Fabrice Chandre2, Livy Williams3, Claire Duménil1, Chantal Menut4 and Thibaud Martin1,5 Abstract Background: Laboratory and field studies showed that repellent, irritant and toxic actions of common public health insecticides reduce human-vector contact and thereby interrupt disease transmission. One of the more effective strategies to reduce disease risk involves the use of long-lasting treated bednets. However, development of insecticide resistance in mosquito populations makes it imperative to find alternatives to these insecticides. Our previous study identified four essential oils as alternatives to pyrethroids: Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum, Cinnamomum zeylanicum. The objectives of this study were to identify active compounds of these essential oils, to characterize their biological activity, and to examine their potential as a treatment for bednets. Methods: We evaluated the electrophysiological, behavioural (repellency, irritancy) and toxic effects of the major compounds of these oils against Anopheles gambiae strain ‘Kisumu’. Results: Aldehydes elicited the strongest responses and monoterpenes the weakest responses in electroantennogram (EAG) trials. However, EAG responses did not correlate consistently with results of behavioral assays. In behavioral and toxicity studies, several of the single compounds did exhibit repellency, irritancy or toxicity in An. gambiae; however, the activity of essential oils did not always correlate with activity expected from the major components. On the contrary, the biological activity of essential oils appeared complex, suggesting interactions between individual compounds and the insect under study. -
Entomotoxicity of Xylopia Aethiopica and Aframomum Melegueta In
Volume 8, Number 4, December .2015 ISSN 1995-6673 JJBS Pages 263 - 268 Jordan Journal of Biological Sciences EntomoToxicity of Xylopia aethiopica and Aframomum melegueta in Suppressing Oviposition and Adult Emergence of Callasobruchus maculatus (Fabricus) (Coleoptera: Chrysomelidae) Infesting Stored Cowpea Seeds Jacobs M. Adesina1,3,*, Adeolu R. Jose2, Yallapa Rajashaker3 and Lawrence A. 1 Afolabi 1Department of Crop, Soil and Pest Management Technology, Rufus Giwa Polytechnic, P. M. B. 1019, Owo, Ondo State. Nigeria; 2 Department of Science Laboratory Technology, Environmental Biology Unit, Rufus Giwa Polytechnic, P. M. B. 1019, Owo, Ondo State. Nigeria; 3 Insect Bioresource Laboratory, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Government of India, Takyelpat, Imphal, 795001, Manipur, India. Received: June 13, 2015 Revised: July 3, 2015 Accepted: July 19, 2015 Abstract The cowpea beetle, Callosobruchus maculatus (Fabricus) (Coleoptera: Chrysomelidae), is a major pest of stored cowpea militating against food security in developing nations. The comparative study of Xylopia aethiopica and Aframomum melegueta powder in respect to their phytochemical and insecticidal properties against C. maculatus was carried out using a Complete Randomized Design (CRD) with five treatments (0, 1.0, 1.5, 2.0 and 2.5g/20g cowpea seeds corresponding to 0.0, 0.05, 0.075, 0.1 and 0.13% v/w) replicated thrice under ambient laboratory condition (28±2°C temperature and 75±5% relative humidity). The phytochemical screening showed the presence of flavonoids, saponins, tannins, cardiac glycoside in both plants, while alkaloids was present in A. melegueta and absent in X. aethiopica. The mortality of C. maculatus increased gradually with exposure time and dosage of the plant powders. -
62 of 17 January 2018 Replacing Annex I to Regulation (EC) No 396/2005 of the European Parliament and of the Council
23.1.2018 EN Official Journal of the European Union L 18/1 II (Non-legislative acts) REGULATIONS COMMISSION REGULATION (EU) 2018/62 of 17 January 2018 replacing Annex I to Regulation (EC) No 396/2005 of the European Parliament and of the Council (Text with EEA relevance) THE EUROPEAN COMMISSION, Having regard to the Treaty on the Functioning of the European Union, Having regard to Regulation (EC) No 396/2005 of the European Parliament and of the Council of 23 February 2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin and amending Council Directive 91/414/EEC (1), and in particular Article 4 thereof, Whereas: (1) The products of plant and animal origin to which the maximum residue levels of pesticides (‘MRLs’) set by Regulation (EC) No 396/2005 apply, subject to the provisions of that Regulation, are listed in Annex I to that Regulation. (2) Additional information should be provided by Annex I to Regulation (EC) No 396/2005 as regards the products concerned, in particular as regards the synonyms used to indicate the products, the scientific names of the species to which the products belong and the part of the product to which the respective MRLs apply. (3) The text of footnote (1) in both Part A and Part B of Annex I to Regulation (EC) No 396/2005 should be reworded, in order to avoid ambiguity and different interpretations encountered with the current wording. (4) New footnotes (3) and (4) should be inserted in Part A of Annex I to Regulation (EC) No 396/2005, in order to provide additional information as regards the part of the product to which the MRLs of the products concerned apply (5) New footnote (7) should be inserted in Part A of Annex I to Regulation (EC) No 396/2005, in order to clarify that MRLs of honey are not applicable to other apiculture products due to their different chemicals character istics. -
Volatiles of Black Pepper Fruits (Piper Nigrum L.)
molecules Article Volatiles of Black Pepper Fruits (Piper nigrum L.) Noura S. Dosoky 1 , Prabodh Satyal 1, Luccas M. Barata 2 , Joyce Kelly R. da Silva 2 and William N. Setzer 1,3,* 1 Aromatic Plant Research Center, Suite 100, Lehi, UT 84043, USA; [email protected] (N.S.D.); [email protected] (P.S.) 2 Programa de Pós-Graduação em Biotecnologia, Universidade Federal do Pará, Belém 66075-110, PA, Brazil; [email protected] (L.M.B.); [email protected] (J.K.R.d.S.) 3 Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA * Correspondence: [email protected]; Tel.: +1-256-824-6519 Academic Editor: Francesca Mancianti Received: 4 October 2019; Accepted: 5 November 2019; Published: 21 November 2019 Abstract: Black pepper (Piper nigrum) is historically one of the most important spices and herbal medicines, and is now cultivated in tropical regions worldwide. The essential oil of black pepper fruits has shown a myriad of biological activities and is a commercially important commodity. In this work, five black pepper essential oils from eastern coastal region of Madagascar and six black pepper essential oils from the Amazon region of Brazil were obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The major components of the essential oils were α-pinene, sabinene, β-pinene, δ-3-carene, limonene, and β-caryophyllene. A comparison of the Madagascar and Brazilian essential oils with black pepper essential oils from various geographical regions reported in the literature was carried out. A hierarchical cluster analysis using the data obtained in this study and those reported in the literature revealed four clearly defined clusters based on the relative concentrations of the major components. -
Chapter 6—Clove Oil (Eugenol)
Chapter 6—Clove Oil (Eugenol) OH CH3 O Eugenol Chapter 6: Clove oil 6-2 6 Table of Contents — Clove Oil (Eugenol) 6.1 INTRODUCTION ......................................................................................................................................... 6-4 6.2 CLOVE OIL AND EUGENOL TOXICITY TO HUMANS AND LEVELS OF CONCERN ................ 6-6 6.2.1 HEALTH EFFECTS ...................................................................................................................................... 6-7 6.2.1.A Acute Effects—Sensitization ........................................................................................................... 6-7 6.2.1.B Acute Effects—Skin, Eyes and Respiratory System ........................................................................ 6-7 6.2.1.C Acute Effects—Systemic Poisoning ................................................................................................ 6-7 6.2.1.D Effects in Human Cells .................................................................................................................... 6-8 6.2.1.E Levels of Concern for Humans ........................................................................................................ 6-8 6.2.2 PESTICIDE ILLNESS REPORTS .................................................................................................................... 6-9 6.3 EUGENOL TOXICITY TO ANIMALS AND PLANTS AND LEVELS OF CONCERN .................... 6-10 6.3.1 MAMMALS .............................................................................................................................................