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Focal Spot, Spring 2006
Washington University School of Medicine Digital Commons@Becker Focal Spot Archives Focal Spot Spring 2006 Focal Spot, Spring 2006 Follow this and additional works at: http://digitalcommons.wustl.edu/focal_spot_archives Recommended Citation Focal Spot, Spring 2006, April 2006. Bernard Becker Medical Library Archives. Washington University School of Medicine. This Book is brought to you for free and open access by the Focal Spot at Digital Commons@Becker. It has been accepted for inclusion in Focal Spot Archives by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. SPRING 2006 VOLUME 37, NUMBER 1 *eiN* i*^ MALLINCKRC RADIOLO AJIVERSITY *\ irtual Colonoscopy: a Lifesaving Technology ^.IIMi.|j|IUII'jd-H..l.i.|i|.llJ.lii|.|.M.; 3 2201 20C n « ■ m "■ ■ r. -1 -1 NTENTS FOCAL SPOT SPRING 2006 VOLUME 37, NUMBER 1 MIR: 75 YEARS OF RADIOLOGY EXPERIENCE In the early 1900s, radiology was considered by most medical practitioners as nothing more than photography. In this 75th year of Mallinckrodt Institute's existence, the first of a three-part series of articles will chronicle the rapid advancement of radiol- ogy at Washington University and the emergence of MIR as a world leader in the field of radiology. THE METABOLISM OF THE DIABETIC HEART More diabetic patients die from cardiovascular disease than from any other cause. Researchers in the Institute's Cardiovascular Imaging Laboratory are finding that the heart's metabolism may be one of the primary mechanisms by which diseases such as diabetes have a detrimental effect on heart function. VIRTUAL C0L0N0SC0PY: A LIFESAVING TECHNOLOGY More than 55,000 Americans die each year from cancers of the colon and rectum. -
It Has Often Been Said That Studying the Depths of the Sea Is Like Hovering In
It has often been said that studying the depths of the sea is like hovering in a balloon high above an unknown land which is hidden by clouds, for it is a peculiarity of oceanic research that direct observations of the abyss are impracticable. Instead of the complete picture which vision gives, we have to rely upon a patiently put together mosaic representation of the discoveries made from time to time by sinking instruments and appliances into the deep. (Murray & Hjort, 1912: 22) Figure 1: Portrait of the H.M.S. Challenger. Prologue: Simple Beginnings In 1872, the H.M.S Challenger began its five- year journey that would stretch across every ocean on the planet but the Arctic. Challenger was funded for a single reason; to examine the mysterious workings of the ocean below its surface, previously unexplored. Under steam power, it travelled over 100,000 km and compiled 50 volumes of data and observations on water depth, temperature and conditions, as well as collecting samples of the seafloor, water, and organisms. The devices used to collect this data, while primitive by today’s standards and somewhat imprecise, were effective at giving humanity its first in-depth look into the inner workings of the ocean. By lowering a measured rope attached to a 200 kg weight off the edge of the ship, scientists estimated the depth of the ocean. A single reading could take up to 80 minutes for the weight to reach bottom. Taking a depth measurement also necessitated that the Challenger stop moving, and accurate mapping required a precise knowledge of where the ship was in the world, using navigational tools such as sextants. -
Cumulated Bibliography of Biographies of Ocean Scientists Deborah Day, Scripps Institution of Oceanography Archives Revised December 3, 2001
Cumulated Bibliography of Biographies of Ocean Scientists Deborah Day, Scripps Institution of Oceanography Archives Revised December 3, 2001. Preface This bibliography attempts to list all substantial autobiographies, biographies, festschrifts and obituaries of prominent oceanographers, marine biologists, fisheries scientists, and other scientists who worked in the marine environment published in journals and books after 1922, the publication date of Herdman’s Founders of Oceanography. The bibliography does not include newspaper obituaries, government documents, or citations to brief entries in general biographical sources. Items are listed alphabetically by author, and then chronologically by date of publication under a legend that includes the full name of the individual, his/her date of birth in European style(day, month in roman numeral, year), followed by his/her place of birth, then his date of death and place of death. Entries are in author-editor style following the Chicago Manual of Style (Chicago and London: University of Chicago Press, 14th ed., 1993). Citations are annotated to list the language if it is not obvious from the text. Annotations will also indicate if the citation includes a list of the scientist’s papers, if there is a relationship between the author of the citation and the scientist, or if the citation is written for a particular audience. This bibliography of biographies of scientists of the sea is based on Jacqueline Carpine-Lancre’s bibliography of biographies first published annually beginning with issue 4 of the History of Oceanography Newsletter (September 1992). It was supplemented by a bibliography maintained by Eric L. Mills and citations in the biographical files of the Archives of the Scripps Institution of Oceanography, UCSD. -
HISTORY Nuclear Medicine Begins with a Boa Constrictor
HISTORY Nuclear Medicine Begins with a Boa Constrictor Marshal! Brucer J Nucl Med 19: 581-598, 1978 In the beginning, a boa constrictor defecated in and then analyzed the insoluble precipitate. Just as London and the subsequent development of nuclear he suspected, it was almost pure (90.16%) uric medicine was inevitable. It took a little time, but the acid. As a thorough scientist he also determined the 139-yr chain of cause and effect that followed was "proportional number" of 37.5 for urea. ("Propor inexorable (7). tional" or "equivalent" weight was the current termi One June week in 1815 an exotic animal exhibi nology for what we now call "atomic weight.") This tion was held on the Strand in London. A young 37.5 would be used by Friedrich Woehler in his "animal chemist" named William Prout (we would famous 1828 paper on the synthesis of urea. Thus now call him a clinical pathologist) attended this Prout, already the father of clinical pathology, be scientific event of the year. While he was viewing a came the grandfather of organic chemistry. boa constrictor recently captured in South America, [Prout was also the first man to use iodine (2 yr the animal defecated and Prout was amazed by what after its discovery in 1814) in the treatment of thy he saw. The physiological incident was common roid goiter. He considered his greatest success the place, but he was the only person alive who could discovery of muriatic acid, inorganic HC1, in human recognize the material. Just a year earlier he had gastric juice. -
Radiocarbon Revolution Chris Turney Applauds a Book on Carbon-14 and Its Key Applications
JAMES KING-HOLMES/SPL JAMES A human femur, thought to be from medieval times, being sampled for carbon dating. GEOSCIENCE Radiocarbon revolution Chris Turney applauds a book on carbon-14 and its key applications. t is nearly 80 years since the discovery — whose discoveries the carefully gathered sample and found that of carbon-14, a radioactive isotope of made possible the it was measurably radioactive. The story of the sixth element. Because its decay can theory, practice and 14C thus began with a dose of high drama. Ibe used to track the passage of time, radio- further findings we Originally expected to have a half-life of carbon has made myriad contributions now take for granted. just minutes or hours, this heavy form of car- across the Earth, environmental, biological There’s enough to sat- bon was considered a low research priority. and archaeological sciences. In the wonder- isfy the most in satiable But Kamen and Ruben’s efforts proved that fully engaging Hot Carbon, oceanographer informavore. it would be stable over millennia, opening up John Marra takes this story much further, Hot Carbon starts a breathtaking number of research avenues exploring not just the science, but why we with the extraordi- (its half-life of 5,730 years was determined should care about it. nary story of chemist Hot Carbon: some years later). Kamen never received the Carbon-14 and Radiocarbon is scarce in nature, formed in Martin Kamen, born a Revolution in credit he deserved, becoming a victim of the the upper atmosphere through the interaction in Canada to Russian Science US anti-communist fervour of the 1940s and of cosmic rays with nitrogen. -
Proceedings of the Fifth International Congress on the History of Oceanography
EVOLUTION OF THE TECTOGENE CONCEPT, 1930-1965 ALlIN O. ALLWARDT SANTA CRUZ, CALIFORNIA Prepared for the Proceedings of the Fifth International congress on the History of oceanography (SCripps Institution of OCeanography, July 7-14, 1993) EVOLUTION OF THE TECTOGENR CONCEPT, 1930-1965 ABSTRACT The tectogene, or crustal downbuckle, was proposed in the early 19305 by F. A. Vening Meinesz to explain the unexpected belts of negative gravity anomalies in island arcs. He attributed the isostatic imbalance to a deep sialic root resulting from the action of subcrustal convection currents. Vening Heinesz's model was initially corroborated experimentally by P. H. Kuenen, but additional experiments by D. T. Griggs and geological analysis by H. H. Hess in the late 19305 led to substantial revision in detail. As modified, the tectogene provided a plausible model for the evolution of island arcs into alpine mountain belts for another two decades. Additional revisions became necessary in the early 19505 to accommodate the unexpected absence of sialic crust in the Caribbean and the marginal seas of the western Pacific. By 1960 the cherished analogy between island arcs and alpine mountain belts had collapsed under the weight of the detailed field investigations by Hess and his students in the Caribbean region. Hess then incorporated a highly modified form of the tectogene into his sea-floor spreading hypothesis. Ironically, this final incarnation of the concept preserved some of the weaker aspects of the 19305 original, such as the ad hoc explanation for the regular geometry of island arcs. EVOLUTION OF THE TECTOGENE CONCEPT, 1930-1965 ALAN O. -
(IKB): Absolute Dating Methods in Archaeology and the Basis Of
14C u okolišu 14C v okolju 14C in environment Ines KRAJCAR BRONIĆ i Jadranka BAREŠIĆ [email protected] IJS, Ljubljana, 9.12.2015. • 14C metoda – uvod, ciklus ugljika, produkcija 14C • Raspodjela ugljika u prirodi (atmosfera) • Određivanje starosti • Veličine i jedinice • Procjena doze • Mjerne tehnike određivanja 14C • Monitoring 14C u okolici NE • Monitoring u okolici NEK 2 Carbon isotopes 12C 13C 14C 98.89 % 1.11 % 10-10 % p = n = 6 n = 7 n = 8 T = 5730 y 1/2 3 U atmosferi - uglavnom kao CO2, 0,03 (0,04)% vol. - važna uloga za održavanje života na Zemlji - koriste biljke za proces fotosinteze ATMOSFERA 580 GtC (18.st) - 750 + (danas) 100 pMC (do 200 pMC u 20.st) Vraća se u -6,5‰ do -8‰ atmosferu disanjem biljaka i životinja, raspadanjem BIOSFERA vegetacija 600 GtC FOSILNA GORIVA biljnog i životinjskog 100 pMC Površinski ocean 10-20000 GtC tkiva, spaljivanjem (-25 ± 5)‰ 800 - 1000 GtC 0 pMC organskog 95 pMC (-25 ± 5)‰ (0 ± 2)‰ materijala, tlo 1600 GtC oslobađanjem iz <100 pMC (-25 ± 5)‰ tople morske vode i SEDIMENTNE STIJENE vulkanskim 66 - 100 x 109 GtC erupcijama. Duboki ocean 0 pMC 38-40000 GtC (0 ± 2)‰ <100 pMC 0 ‰ CO se otapa u morskoj vodi (veća 2 Izgaranjem fosilnih goriva oslobađa topivost u hladnijoj vodi), a i u vodi 4 se ugljik koji je milijunima godina koja prolazi kroz tlo, stvarajući bio spremljen u litosferi. ugljičnu kiselinu, koja može otapati vapnenačke stijene. Discovery of 14C Obituary Martin Kamen Scientist, co-discoverer of the isotope that gave archaeology carbon-dating, and innocent victim of America's Communist witchhunts (Pearce Wright , The Guardian, Monday 9 September 2002) The American scientist Professor Martin Kamen was the co-discoverer of the radioactive isotope carbon-14. -
Seu Valor Científico- MONTEIRO Histórico E Didáctico
Universidade de Aveiro Departamento de Didáctica e Tecnologia Educativa 2007 GRAÇA MARIA VIANA Controvérsias Geológicas: seu valor científico- MONTEIRO histórico e didáctico Tese apresentada à Universidade de Aveiro para cumprimento dos requisitos necessários à obtenção do grau de Doutor em Didáctica, realizada sob a orientação científica do Dr. João José Félix Marnoto Praia, Professor associado com agregação (aposentado pela Faculdade de Ciências da Universidade do Porto) do Departamento de Didáctica e Tecnologia Educativa e Dr. António Soares de Andrade, Professor associado aposentado pela Universidade de Aveiro do Departamento de Geociências da Universidade de Aveiro. o júri presidente Prof. Doutor Henrique Manuel Morais Diz Professor Catedrático da Universidade de Aveiro Prof. Doutor Vítor Manuel de Sousa Trindade Professor Catedrático da Universidade de Évora Prof. Doutor João José Félix Marnoto Praia Professor Associado com Agregação Aposentado pela Faculdade de Ciências da Universidade do Porto (Orientador) Prof. Doutor Luís Manuel Ferreira Marques Professor Associado com Agregação da Universidade de Aveiro Prof. Doutor Luís Carlos Gama Pereira Professor Associado da Faculdade de Ciências e Tecnologia da Universidade de Coimbra Prof. Doutor Alfredo de Oliveira Dinis Professor Associado da Faculdade de Filosofia de Braga da Universidade Católica Portuguesa Prof. Doutor António Augusto Soares de Andrade Professor Associado Aposentado da Universidade de Aveiro (Co-Orientador) agradecimentos Este trabalho teve início em Setembro de 2003 e, ao longo de quatro anos, houve um caminho percorrido que permitiu a sua concretização. Torna-se grato recuar no tempo e verificar que as primeiras palavras de gratidão vão para os Sr. Professor Doutor João Félix Marnoto Praia e Sr. Professor Doutor António Soares de Andrade cuja orientação, persistência e disponibilidade tornaram possível o alcance dos objectivos que eu pretendia atingir. -
Memorial of Harry Hammond Hess May 24, 1906-August 25, 1969
MEMORIALS 415 he snapped,"I'll give you five hundred dollars for Upon his return to civilian life Martin moved to it," and the sale was made. It was momentslike Los Angelesand went into the wholesalediamond this that Martin relishedand made life for him an business.However, this highly competitive business excitingadventure. was not to his liking and he returned once more to Martin becameinterested in artificial coloration of dealing in minerals. He travelled the wodd over diamondsin 1940.During that period he and Harry countless times in the ensuing years, seeking out Berman conducted experiments with the Harvard important specimens,buying or exchangingfor in- cyclotron.After the war he continuedhis experi- dividual pieces or entire collections. The best of ments at the University of California (Berkeley) these he offered to the museumshe was dedicated with JosephE. Hamilton and Thomas M. Putnam to serve.The balancehe would disposeof as quickly of the Crocker Laboratory. The results of their as possibleto other dealers,meanwhile planning his work, "Effect of heavy charged particle and fast next trip. neutron irradiation on diamonds," was published Martin also had an uncannyability to judge the in The American Mineralogistin 1952. value of gemstones,both finishedgems and rough. In early 1942 Maftin volunteeredfor service in This made it possiblefor him to find financial back- the United StatesArmy. He receivedta direct com- ers for his travels and purchases.Some of his trips mission as Cap'tain and rose to the rank of Lt. were primarily to buy gems and gem rough. But al- Colonel. He was assigrredto the Bomb Disposal ways, even on these trips, he managedto ferret out Schoolat Aberdeen,Maryland, and eventuallybe- many choicemineral specimens,and in this he found came commandingofficer of the school. -
Histoire De La Théorie De La Tectonique Des Plaques
1/12 Histoire de la théorie de la tectonique des plaques 06/06/2011 Auteur(s) : Vincent Deparis Lycée Jean Monnet - Annemasse vincent.deparis(à)neuf.fr Publié par : Olivier Dequincey Résumé Histoire et évolution de la théorie de la tectonique des plaques à partir de celle de la dérive des continents. Table des matières L'hypothèse de l'expansion des fonds océaniques La formulation de la théorie de la tectonique des plaques La tectonique des plaques et la géologie La tectonique des plaques et la Terre Les articles fondateurs de la théorie de la tectonique des plaques et leurs résumés Bibliographie Cet article fait partie de la série de 4 articles écrits par Vincent Deparis et/ou Pierre Thomas et consacrés à l'histoire de la tectonique des plaques : La dérive des continents de Wegener, La découverte de la convection mantellique, Histoire de la théorie de la tectonique des plaquesetLa tectonique des plaques de 1970 à 2011. Avertissement : les images disponibles dans ce dossier ne sont pas libres de droits. Elles proviennent du site de l'USGS, et de la bibliographie. La théorie de la tectonique des plaques a vu le jour à la fin des années 1960. Reprenant les conceptions mobilistes de Wegener, elle les développe et leur fournit une assise théorique solide en s'appuyant sur l'hypothèse alors toute récente de l'expansion des fonds océaniques. Universellement adoptée aujourd'hui, elle constitue le nouveau paradigme des sciences de la Terre. Elle offre un modèle cinématique remarquable des mouvements horizontaux à grande échelle à la surface du globe. -
Foreword by Edwin M
Foreword by Edwin M. McMillan I first met Martin Kamen in 1937, when he came to Ernest Lawrence's Radiation Laboratory at the University of California in Berkeley as a newly minted Ph.D. in Chemistry from the University of Chicago on a research fellowship. To set the stage for that event I should say something about what the laboratory was like then. It bore no resemblance to any modern research establishment. It had one building, an old wooden structure that had been scheduled for demoli- tion until Lawrence prevailed on Robert G. Sproul, then president of U.C., to save it for him. In this building worked a small group of dedi- cated people, some of them faculty, some graduate students, some visitors and fellows, under Lawrence's direction. There was no formal organization and no set program of research, and a newcomer like Martin pretty much had to find his own way. The fact that he was a chemist in a group dominated by physicists was no problem; there was plenty of chemistry to be done in the identification and purification of radioactive isotopes, and anyhow the kind of chemistry that he had. learned under William D. Harkins at Chicago had a large component of nuclear physics mixed with it. Then, too, there was Martin's friendly and cheerful personality, with its many facets and some eccentricities, such as his refusal to learn to drive a car. His stories of life in the seamier parts of Chicago added a touch of exotic interest, as did his tales of life as a graduate student with some dictatorial professors of the old school. -
Photosynthesis: Converting Radiant Energy Into Chemical Energy the Light-Independent Reactions
Photosynthesis: Converting Radiant Energy into Chemical Energy The Light-Independent Reactions The Laws of Nature describe, predict, and explain how and why events occur in nature. The Laws of Nature serve as summaries of a large number of observations and experimental results that have taken place since the time humans began questioning. Once enounced and accepted, the Laws of Nature seem right, true, self-evident, and the basis of building higher-level systems of reason, whether scientific or political, based on the always testable assumption that the law is true. The Laws of Nature can be called Principles. Thomas Jefferson, John Adams and Benjamin Franklin used the Laws of Nature to justify the separation of the American colonies from England in the Declaration of Independence: “When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature's God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel them to the separation. We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness….” The Laws of Nature are principles but they may not always apply to every situation. In a healthy society, the application of the Laws of Nature are questioned.