Eosinophil myeloblast Eosinophil metamyelocyte Eosinophil myelocyte Eosinophil promyelocyte Refractory anemia with ringed sideroblasts AML with mutated NPM1 Myeloid leukemia associated with Down syndrome Juvenile myelomonocytic leukemia Common dendritic progenitor AML with minimal differentiation Therapy−related myeloid neoplasms Basophil progenitor Acute basophilic leukemia Mixed phenotype acute leukemia, B−myeloid, not otherwise specified Basophil myeloblast Basophil metamyelocyte Basophil myelocyte Basophil promyelocyte Acute myeloid leukemia with myelodysplasia−related changes Acute panmyelosis with myelofibrosis AML with mutated CEBPA Acute myeloid leukemia with recurrent genetic abnormalities Chronic neutrophilic leukemia Acute leukemias of ambiguous lineage Childhood myelodysplastic syndrome Refractory cytopenia with multilineage dysplasia Myelodysplastic/myeloproliferative neoplasm, unclassifiable Myelodysplastic syndrome, unclassified Myeloid proliferations related to Down syndrome AML with t(6;9)(p23;q34); DEK−NUP214 fusion AML (megakaryoblastic) with t(1;22)(p13;q13); RBM15−MKL1 AML with t(8;21)(q22;q22); RUNX1−RUNX1T1 fusion gene AML with t(9;11)(p22;q23); MLLT3−MLL fusion gene APL with t(15;17)(q22;q12); PML−RAR.... fusion gene Anaplastic lymphoma kinase−positive large B cell lymphoma Atypical chronic myeloid leukemia, BCR−ABL1...... negative B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22) TEL−AML1 (ETV6−RUNX1) B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3);TCF3−PBX1 B lymphoblastic leukemia/lymphoma with t(5;14)(q31;q32) IL3−IGH B lymphoblastic leukemia/lymphoma with t(9;22)(q34;q11.2);BCR−ABL 1 B lymphoblastic leukemia/lymphoma with t(v;11q23);MLL rearranged CD4+ T follicular helper cell Classical Hodgkin lymphoma type post−transplantation lymphoproliferative disorder Infectious mononucleosis−like post−transplantation lymphoproliferative disorder Intravascular large B cell lymphoma Large B cell lymphoma Memory B cell Mixed phenotype acute leukemia with t(9;22)(q34;q11.2); BCR−ABL1 Mixed phenotype acute leukemia with t(v;11q23); MLL rearranged Mixed phenotype acute leukemia, T−myeloid, not otherwise specified Myelodysplastic syndrom with isolated del(5q) NK T cell Primary mediastinal large B cell lymphoma Refractory anemia with ring sideroblasts and thrombocytosis Splenic diffuse red pulp small B cell lymphoma T cell histiocyte rich large B cell lymphoma T lymphoblastic leukemia/lymphoma Pro−NK cell Basophil−mast cell progenitor Refractory cytopenia with unilineage dysplasia B lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities Disseminated juvenile xanthogranuloma Myeloproliferative neoplasms, unclassifiable Refractory cytopenia with multilineage dysplasia and ringed sideroblasts Polymorphic post−transplantation lymphoproliferative disorder Refractory cytopenia of childhood Transient abnormal myelopoiesis B lymphoblastic leukemia/lymphoma with hypodiploidy Pre−NK cell Systemic EBV−positive T−cell lymphoproliferative disease of childhood Myelodysplastic/myeloproliferative syndromes Fibroblastic reticular cell tumor Primary cutaneous follicle centre lymphoma Monomorphic post−transplantation lymphoproliferative disorder Diffuse large B cell lymphoma associated with chronic inflammation B cell lymphoma, unclassifiable, with features intermediate between DLBCL and classical Hodgkin lymphoma B cell lymphoma, unclassifiable, with features intermediate between DLBCL and Burkitt lymphoma Myeloid and lymphoid neoplasms associated with FGFR1 abnormalities Myeloid and lymphoid neoplasms associated with PDGFRA rearrangement Myeloid neoplasms associated with PDGFRB rearrangement Hydroa vacciniforme−like lymphoma Metallophilic macrophage Late pro−B cell B lymphoblastic leukemia/lymphoma with hyperdiploidy Basophilic erythroblast Primary lymphoma of the thyroid Primary cutaneous DLBCL, leg type Small pre−B cell Large pre−B cell Nonclassical monocyte Histiocytic and dendritic cell neoplasms Langerhans cell sarcoma Interdigitating dendritic cell sarcoma Early pro−B cell Solitary plasmacytoma of bone Alpha−heavy chain disease Primary cutaneous gamma−delta T−cell lymphoma Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T−cell lymphoma Primary cutaneous CD4+ small/medium T−cell lymphoma Lymphomatoid granulomatosis Extranodal natural killer/T−cell lymphoma, nasal type Refractory neutropenia Post−transplantation lymphoproliferative disorders Anaplastic large cell lymphoma, ALK−negative Nodular sclerosis classical Hodgkin lymphoma Chronic eosinophilic leukemia, not otherwise specified Late double−positive T cell Late double−negative T cell Pro−T cell Lymphoblast Subcutaneous panniculitis−like T−cell lymphoma Enteropathy−associated T−cell lymphoma Plasmacytic hyperplasia White pulp macrophage Tissue−resident macrophages Red pulp macrophage Pleural macrophage Marginal zone macrophage Intermediate dendritic cell tumor Follicular dendritic cell sarcoma B cell prolymphocytic leukemia Splenic marginal zone lymphoma Hairy cell leukemia variant Epstein Barr virus positive DLBCL of the elderly Classic Hodgkin lymphoma Anaplastic large cell lymphoma, ALK−positive Histiocytic sarcoma Pure erythroid leukemia Erythroleukemia, erythroid/myeloid Reticulocyte Immature lymphoid neoplasms Refractory anemia Chronic myelomonocytic leukemia Myeloid sarcoma Myeloproliferative neoplasms Mast cell progenitor Refractory anemia with excess blasts Eosinophil progenitor Primary myelofibrosis Polycythemia vera Essential thrombocythemia Acute undifferentiated leukemia Acute megakaryoblastic leukemia Neutrophil metamyelocyte Neutrophil myelocyte Neutrophil myeloblast Neutrophil promyelocyte Chronic lymphoproliferative disorder of NK cells Mature NK cell neoplasms NK cell large granular lymphocyte leukemia T−cell large granular lymphocytic leukemia Natural killer (NK) cell lymphoblastic leukemia/lymphoma Aggressive NK−cell leukemia T−cell prolymphocytic leukemia Hepatosplenic T−cell lymphoma Angioimmunoblastic T−cell lymphoma CD56bright NK cell CD56dim NK cell Blastic plasmacytoid dendritic cell neoplasm Plasmablastic lymphoma Primary cutaneous B cell lymphoma Primary lymphoma of bone Primary effusion lymphoma Primary central nervous system lymphoma Refractory thrombocytopenia Lymphoplasmacytic lymphoma Adipose−tissue associated macrophage Myeloid and lymphoid neoplasms associated with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1 Primary cutaneous anaplastic large cell lymphoma Lymphomatoid papulosis Primary cutaneous CD30+ T−cell lymphoproliferative disorders Proerythroblast Normoblast Polychromotophilic erythroblast Acute erythroid leukemia Acute monoblastic/monocytic leukemia Langerhans cell histiocytosis Classical monocyte Intermediate monocyte Placental macrophage Kupffer cell Dermal macrophage Classical dendritic cell Tumor−associated macrophage Pre−T cell Early double−negative T cell Early double−positive T cell S....zary syndrome Immature NK cell Myeloid−derived suppressor cell Basophil Mu−heavy chain disease Gamma−heavy chain disease Heavy chain diseases Mature B−cell neoplasms Hairy cell leukemia Pre−B cell Immature B cell Burkitt lymphoma Acute myelomonocytic leukemia Mastocytosis Nodal marginal zone lymphoma Marginal zone B−cell lymphoma MALT lymphoma Mantle cell lymphoma Follicular lymphoma Alveolar macrophage Intestinal macrophage Peritoneal macrophage Microglia Mature T cell neoplasms Adult T−cell leukemia/lymphoma Early lesions Splenic lymphoma Mycosis fungoides CD8+CD45RA+ effector memory T cell CD4+ central memory T cell CD8+ central memory T cell Peripheral T−cell lymphoma Megakaryocyte progenitor Promegakaryocyte Megakaryoblast Granulocyte monocyte progenitor Erythrocyte progenitor Neutrophil progenitor Monocyte progenitor Megakaryocyte erythrocyte progenitor Common lymphoid progenitor Chronic myelogenous leukemia, BCR−ABL1...... positive Myelodysplastic syndromes Megakaryocyte Multiple myeloma Mast cell Bone−marrow macrophage Osteoclast Mixed cellularity classical Hodgkin lymphoma Lymphocyte−depleted classical Hodgkin lymphoma Lymphocyte−rich classical Hodgkin lymphoma Nodular lymphocyte predominant Hodgkin lymphoma Diffuse large B cell lymphoma Hodgkin Lymphoma B lymphoblastic leukemia/lymphoma B lymphoblastic leukemia/lymphoma, not otherwise specified Mature B cell Chronic lymphocytic leukemia Lymphoid neoplasms AML without maturation AML with maturation Acute myeloid leukemia Acute myeloid leukemia, not otherwise specified Common myeloid progenitor Erythrocyte Tumor−infiltrating lymphocyte CD8+ effector memory T cell Gamma delta T cell CD4+ effector memory T cell CD4+ Th17 T cell Eosinophil Thrombocyte Thymocyte CD8+ Naive T cell Neutrophil Neutrophil band cell Hematopoietic stem cell CD4+ helper T cell CD4+ Th1 T cell CD4+ Naive T cell CD4+ Th2 T cell Plasma cell Plasmacytoid dendritic cell CD4+ regulatory T cell CD8+ cytotoxic T cell B cell Macrophage T cell CD8 CD4 CD3 CD5 CD2 CD1 CD7 CD6 CD9 CD34 CD25 CD35 CD18 CD68 CD14 CD40 CD86 CD80 CD28 CD45 CD20 CD19 CD56 CD95 CD83 CD27 CD57 CD54 CD44 CD16 CD69 CD30 CD38 CD10 CD23 CD15 CD13 CD33 CD36 CD31 CD79 CD43 CD21 CD22 CD64 CD11 CD71 CD55 CD59 CD58 CD29 CD26 CD63 CD90 CD61 CD41 CD52 CD24 CD73 CD48 CD70 CD94 CD47 CD32 CD81 CD46 CD39 CD62 CD66 CD74 CD77 CD72 CD37 CD99 CD98 CD51 CD89 CD67 CD88 CD87 CD91 CD50 CD82 CD53 CD65 CD96 CD42 CD93 CD97 TIGIT CD60 CD84 CD75 CD76 CD85 CD49 CD78 CD92 CD1A CD3E CD1B CD8A CD8B CD1E CD1D CD1C CD3D CDw1 CD3G CD85I CD85J CD115 CD124 CD154 CD127 CD62L CD152 CD220 CD257 CD269 CD265 CD126 CD106 CD117 CD163 CD138 CD128 CD279 CD134 CD274 CD103 CD137 CD271 CD340 CD143 CD141 CD133 CD105 CD123 CD150 CD161 CD122 CD252 CD132 CD206 CD205 CD209 CD207 CD177 CD147 CD222 CD221 CD200 CD270 CD223 CD244 CD276 CD226 CD125 CD166 CD146 CD204 CD169 CD162 CD303 CD208 CD107 CD160 CD100 CD116 CD184 CD135 CD144 CD317 CD104 CD101 CD153 CD178 CD155 CD102 CD148 CD180 CD164 CD292 CD151 CD301 CD300 CD172 CD130 CD168 CD247 CD158 CD112 CD326 CD304 CD273 CD229 CD319 CD272 CD305 CD321 CD142 CD109 CD157 CD114 CD235 CD110 CD119 CD131 CD195 CD254 CD357 CD275 CD197 CD294 CD183 CD171 CD248 CD227 CD314 CD278 CD277 CD309 CD203 CD335 CD352 CD196 CD336 CD225 CD361 CD256 CD268 CD267 CD185 CD307 CD316 CD320 CD108 CD329 CD255 CD264 CD362 CD302 CD299 CD111 CD341 CD201 CD170 CD165 CD118 CD212 CD210 CD120 CD159 CD338 CD310 CD253 CD249 CD281 CD246 CD140 CD311 CD343 CD342 CD243 CD258 CD280 CD156 CD324 CD191 CD233 CD239 CD176 CD242 CD284 CD217 CD193 CD262 CD337 CD353 CD351 CD215 CD363 CD360 CD358 CD355 CD312 CD296 CD129 CD182 CD354 CD282 CD297 CD231 CD315 CD230 CD167 CD331 CD263 CD322 CD261 CD181 CD192 CD238 CD344 CD173 CD349 CD339 CD318 CD174 CD350 CD323 CD232 CD306 CD359 CD356 CD348 CD347 CD346 CD334 CD333 CD332 CD330 CD328 CD327 CD325 CD313 CD308 CD298 CD295 CD291 CD290 CD289 CD288 CD287 CD286 CD285 CD283 CD266 CD260 CD259 CD251 CD250 CD245 CD241 CD240 CD237 CD236 CD234 CD228 CD219 CD218 CD216 CD214 CD213 CD211 CD202 CD194 CD190 CD189 CD188 CD187 CD186 CD179 CD139 CD121 CD136 CD345 CD224 CD113 CD175 CD49F CD85F CD66F CD11B CD62P CD11A CD62E CD42B CD79B CD79A CD66E CD49B CD66B CD49E CD16B CD32A CD66A CD42A CD49A CD32B CD16A CD85K CD60A CD60B CD85A CD85E CD85B CD11C CD42C CD42D CD45R CD49D CDw29 CDw17 CD66C CD49C CD11D CD66D CDw14 CDw12 CD85D CD60C CD32C CDw21 CDw19 CD85H CD85C CD85G CD158I CD158J CD300F CD158Z CD235A CD120B CD107A CD163B CD140B CD140A CD158E CD172A CD158A CD107B CD120A CD158K CD300A CD121A CD159A CD179B CD179A CD307A CD307B CD300E CD300B CD156B CD167A CD203A CD121B CD156A CD218A CD202B CD307E CD235B CD218B CD172B CD167B CD203C CD300C CD307D CD159C CD158D CDw149 CD300D CD307C CDw293 CDw199 CDw198 CDw145 CD240D CD158H CD158C CD156C CD300G CD172G CD158G CD45RA CD45RB CD45RC CD45RO CD158F2 CD158F1 CD158B1 CD213A2 CD213A1 CD158B2 CDw210B CD240CE CD45RAB CD45RAC CD45RBC

FIGURE 1 | Heat map of CD molecule expression data availability in primary literature. PubMed was queried with combinations of each CD molecule with each hematopoietic cell (including common aliases for both). Light gray cells in the heat map correspond to 0 hits in PubMed for the cell and CD molecule combination, the shades of blue corresponds to 10–100 hits ( to dark), and green corresponds to 1000+ hits. See Supplementary Figure 1 for high-resolution figure with row and column names.