Before the Postal Rate Commission Washington, D
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(12) United States Patent (10) Patent N0.: US 8,283,294 B2 Kastrup Et A]
US008283294B2 (12) United States Patent (10) Patent N0.: US 8,283,294 B2 Kastrup et a]. (45) Date of Patent: Oct. 9, 2012 (54) METHOD FOR CLONING COGNATE FOREIGN PATENT DOCUMENTS ANTIBODIES FR 2724393 3/1996 W0 WO 92/15678 Al 9/1992 (75) Inventors: Jesper Kastrup, Stenlose (DK); Lars S. W0 WO 93/03151 Al 2/1993 Nielsen, Niva (DK); Per-Johan Meijer, W0 WO 93/20227 A1 10/1993 Copenhagen (DK) W0 WO 94/08008 Al 4/1994 W0 WO 95/20401 Al 8/1995 (73) Assignee: Symphogen A/S, Lyngby (DK) W0 WO 96/08564 Al 4/1996 W0 WO 98/57994 A2 12/1998 ( * ) Notice: Subject to any disclaimer, the term of this W0 WO 99/16904 Al 4/1999 patent is extended or adjusted under 35 W0 WO 99/29888 Al 5/1999 U.S.C. 154(b) by 122 days. W0 WO 01/89563 A1 11/2001 W0 WO 01/92291 A2 12/2001 (21) Appl.No.: 12/074,066 WO 2004/003019 * 6/2004 (22) Filed: Feb. 29, 2008 W0 WO 2004/061104 A2 7/2004 (65) Prior Publication Data W0 WO 2005/042774 A2 5/2005 W0 WO 2006/007850 Al l/2006 US 2008/0227660 A1 Sep. 18, 2008 W0 WO 2006/007853 A2 l/2006 W0 WO 2007/003041 Al l/2007 W0 WO 2007/101441 Al l/2007 Related US. Application Data W0 WO 2007/065433 A2 6/2007 (60) Provisional application No. 60/904,772, ?led on Mar. OTHER PUBLICATIONS 5, 2007. Rudikoff et al (Proc Natl Acad Sci USA 1982 vol. -
Informa 2018 Full Year Results Statement
Informa LEI: 5493006VM2LKUPSEDU20 Press Release 7 March 2019 Informa PLC Results for 12 Months to 31 December 2018 2018: Combination & Creation 2019: Performance & Growth KEY FINANCIAL AND OPERATING HIGHLIGHTS1 • Strong Revenue Growth: +3.7% underlying and +34.9% reported to £2,369.5m, including six months of UBM (2017: £1,756.8m) • Higher Adjusted Operating Profit: +2.3% underlying and +34.4% reported to £732.1m (2017: £544.9m) • Improved Statutory Operating Profit: £363.2m (2017: £344.7m) • Increased Adjusted Diluted Earnings per Share: +7.0% to 49.2p (2017: 46.0p); Statutory EPS of 19.7p (2017: 37.6p), with prior year including non-cash credit from US tax reforms • Attractive Free Cash Flow: £503.2m and £600m+ including a full year of UBM (2017: £400.9m) • Robust Balance Sheet, in line with plan: Net debt/EBITDA1 at 2.9x (2017: 2.5x) • Enhanced Dividend: up 7.1% to 21.90p (2017: 20.45p) London: Informa (LSE: INF.L), the International Exhibitions, Events, Information Services and Scholarly Research Group, today published its financial results for the 12 months to 31 December 2018, reporting a further period of operational progress and improving financial performance. Stephen A. Carter, Group Chief Executive, said: “In 2018, the Informa Group delivered a fifth consecutive year of improving growth, increasing adjusted profits, adjusted earnings per share, cashflow and dividends.” He added: “In 2019, our focus is on continuing Performance and Growth as we consolidate our market positions and further reduce complexity. This will enable -
Research Library Page 1
Alumni - Research Library Title Citation Abstract Full_Text Pub Type Publisher Subject 100 Great Business Ideas : from Leading Companies Around the 1/1/2009- 1/1/2009- 1/1/2009- Marshall Cavendish World 1/1/2009 1/1/2009 1/1/2009 Books International (Asia) Pte Ltd BUSINESS AND ECONOMICS 100 Great Sales Ideas : from Leading Companies 1/1/2009- 1/1/2009- 1/1/2009- Marshall Cavendish Around the World 1/1/2009 1/1/2009 1/1/2009 Books International (Asia) Pte Ltd BUSINESS AND ECONOMICS 1/1/1988- 1/1/1988- INTERIOR DESIGN AND 1001 Home Ideas 6/1/1991 6/1/1991 Magazines Family Media, Inc. DECORATION 3/1/2002- 3/1/2002- Oxford Publishing 20 Century British History 7/1/2009 7/1/2009 Scholarly Journals Limited(England) HISTORY--HISTORY OF EUROPE 33 Charts [33 Charts - 12/12/2009 12/12/2009- 12/12/2009 BLOG] + 6/3/2011 + Other Resources Newstex CHILDREN AND YOUTH--ABOUT COMPUTERS--INFORMATION 50+ Digital [50+ Digital, 7/28/2009- 7/28/2009- 7/28/2009- SCIENCE AND INFORMATION LLC - BLOG] 2/22/2010 2/22/2010 2/22/2010 Other Resources Newstex THEORY IDG 1/1/1988- 1/1/1988- Communications/Peterboro COMPUTERS--PERSONAL 80 Micro 6/1/1988 6/1/1988 Magazines ugh COMPUTERS 11/24/2004 11/24/2004 11/24/2004 Australian Associated GENERAL INTEREST PERIODICALS-- AAP General News Wire + + + Wire Feeds Press Pty Limited UNITED STATES AARP Modern Maturity; 2/1/1988- 2/1/1988- 2/1/1991- American Association of [Library edition] 1/1/2003 1/1/2003 11/1/1997 Magazines Retired Persons GERONTOLOGY AND GERIATRICS American Association of AARP The Magazine 3/1/2003+ 3/1/2003+ Magazines Retired Persons GERONTOLOGY AND GERIATRICS ABA Journal 8/1/1972+ 1/1/1988+ 1/1/1992+ Scholarly Journals American Bar Association LAW ABA Journal of Labor & Employment Law 7/1/2007+ 7/1/2007+ 7/1/2007+ Scholarly Journals American Bar Association LAW MEDICAL SCIENCES--NURSES AND ABNF Journal 1/1/1999+ 1/1/1999+ 1/1/1999+ Scholarly Journals Tucker Publications, Inc. -
Corporate Responsibility Report 2008
Corporate Responsibility Report 2008 Strength through responsibility Summary Reed Elsevier Corporate Responsibility Report 2008 Chief Executive’s introduction Governance People Our true performance as a company must take account of both our non-financial and financial results. They are intrinsically linked – if we want to be a profitable and successful company, we must be an ethical one. We are committed to being both. To that end, we have been building on our expertise and engaging with stakeholders to find ways to innovate and improve. Health and safety In developing online solutions to the needs of our customers in areas like health, science and technology, law, environment, and business, we benefit society. For example, Procedures Consult gives doctors a way of maintaining their skills and knowledge through web-based simulation of essential medical techniques; TotalPatent is a single source for global patents, a primary driver in research and development; XpertHR helps practitioners advance good practice in people management; energylocate aggregates our energy offerings into a one-stop community, using tools like social networking and video to advance knowledge. Customers Innovation is also helping advance our internal corporate responsibility: > Increased online training in our Code of Ethics and Business Conduct has led to more of our people understanding what it means to do the right thing > A new global jobs board illuminates our value, Boundarylessness, by allowing employees to search for new positions across locations, functions, -
Competitive Implications of Environmental Regulation
Competitive Implications of Environmental Regulation A Study of Six lndustries The Management Institute for Environment and Business 1101 17th Street, NW, Suite 502 Washington, DC 20036 (202) 833-6556 with the U.S. Environmental Protection Agency Printed on processed chlorine free recycled paper: This paper is manufactured without the use of chlorine or chlorine derivatives. It contains 20% post-consumer waste. CONTENTS Competitive Implications of Environmental Regulations Executive Summary ............................................ .i The Pulp and Paper Industry ...................................... .7 The Computer and Electronic Component Industry ....................... 119 The Paint and Coatings Industry ................................... 189 The Refrigerator Industry ....................................... 251 The Dry Cell Battery Industry .................................... 317 The Printing Ink Industry. ....................................... 357 DISCLAIMER Although prepared with EPA funding, this report has neither been reviewed nor approved by the U.S. Environmental Protection Agency for publication as an EPA report. The contents do not necessarily reflect the views or policies of the U.S. Environmental Protection Agency. nor does mention of trade names or commercial products constitute endorsement or recommendation for use. Executive Summary EXECUTIVE SUMMARY Competitive Implications of Environmental Regulation The following industry studies were conducted in 1993 and 1994 to examine the role that environmental regulations play in determining competitive advantage. The six industries -- paint and coatings, pulp and paper, computers and electronic components, refrigerators, batteries, and printing inks -- have three common characteristics. They are global industries, they face significant environmental challenges, and the U.S. is a leading producer. In aggregate, these industries comprise world sales of $160 billion per year. This project was a collaboration between the Management Institute for Environment and Business, Hochschule St. -
Menschen Märkte Medien Management
Menschen Märkte Medien Management Berichte aus Forschung und Lehre 03/2007 Aspects of Digital Game Culture The Cases of Eastern Europe and China Sven Jöckel (Hrsg.) MMMM – 03/2007 Gaming Culture 2/111 Table of Content Foreword ...........................................................................................................................................3 Study 1 ...............................................................................................................................................5 Eastern European Gaming Cultures..........................................................................................6 1. Introduction..................................................................................................................................6 2. Digital games market in Eastern Europe..............................................................................7 3. Method of research ..................................................................................................................12 4. Results.........................................................................................................................................13 5. Conclusions ...............................................................................................................................26 6. Sources .......................................................................................................................................27 Study 2 .............................................................................................................................................28 -
MGM TV Expands Globally TV
Variety.com - MGM TV expands globally Page 1 of 4 VARIETY INDUSTRY NEWS WEB S E A RC H DIGITA L SEARCH POWERED BY: DEPARTMENTS SECTIONS FILM TV INT'L BIZ MUSIC TECH LEGIT HOME ENT. V PLUS REVIEWS BLOGS MORE TV Posted: Tue., Apr. 17, 2007, 9:41am PT MGM TV expands globally 'Stargate' franchise morphs into film By ELIZABETH GUIDER CANNES -- The Lion is back on the Croisette for this week's Mip TV, this time to roar about its international channels biz and its stalwart "Stargate" TV franchise, the longest-running sci-fi skein in history. And back home, MGM's newly revived home entertainment unit is trumpeting an ambitious slate of project extensions, based on properties already in the Lion's den. At a press lunch Tuesday in Cannes, the studio's international networks prexy Bruce Tuchman put the accent on the company's "rapid expansion" of channels, both in terms of geographical reach and subscriber growth. Since Mipcom last October, "we've made tremendous progress," he said. Company has set up a joint-venture channel in the Czech Republic, Hungary and Romania with Liberty Global, and with partner ITI in Poland for an HD channel. MGM's 'Stargate' is TV's longest- running sci-fi series. Launches in India, Russia and Korea also are on the upswing with subs. The MGM channel brand has not yet cracked the difficult but potentially lucrative U.K., French and Italian markets. The studio is not willing to pay for carriage in those difficult territories, but believes its moves to convert many of its movies to high-def will eventually help it get a foothold in those territories. -
CA - FACTIVA - SP Content
CA - FACTIVA - SP Content Company & Financial Congressional Transcripts (GROUP FILE Food and Drug Administration Espicom Company Reports (SELECTED ONLY) Veterinarian Newsletter MATERIAL) (GROUP FILE ONLY) Election Weekly (GROUP FILE ONLY) Health and Human Services Department Legal FDCH Transcripts of Political Events Military Review American Bar Association Publications (GROUP FILE ONLY) National Endowment for the Humanities ABA All Journals (GROUP FILE ONLY) General Accounting Office Reports "Humanities" Magazine ABA Antitrust Law Journal (GROUP FILE (GROUP FILE ONLY) National Institute on Alcohol Abuse and ONLY) Government Publications (GROUP FILE Alcoholism's Alcohol Research & ABA Banking Journal (GROUP FILE ONLY): Health ONLY) Agriculture Department's Economic National Institute on Drug Abuse NIDA ABA Business Lawyer (GROUP FILE Research Service Agricultural Outlook Notes ONLY) Air and Space Power Journal National Institutes of Health ABA Journal (GROUP FILE ONLY) Centers for Disease Control and Naval War College Review ABA Legal Economics from 1/82 & Law Prevention Public Health and the Environment Practice from 1/90 (GROUP FILE ONLY) CIA World Factbook SEC News Digest ABA Quarterly Tax Lawyer (GROUP FILE Customs and Border Protection Today State Department ONLY) Department of Energy Documents The Third Branch ABA The International Lawyer (GROUP Department of Energy's Alternative Fuel U.S. Department of Agricultural FILE ONLY) News Research ABA Tort and Insurance Law Journal Department of Homeland Security U.S. Department of Justice's -
An Empirical Study of Domestic Airline Industry in India Abstract
DIMENSIONS OF CUSTOMER SERVICE QUALITY - AN EMPIRICAL STUDY OF DOMESTIC AIRLINE INDUSTRY IN INDIA ABSTRACT OF THE THESIS SUBMITTED FOR THE AWARD OF THE DEGREE OF Ph. D. (BUSINESS ADMINISTRATION) BY . VIPPAN RAJ DUTTT Under the Supervision of Dr. Mohammed Naved Khan' ; Dr. S C Bansal Senior Lecturer ' , » Associate Professor Department of Business Administration Indian Institute of Management Faculty of Mgt. Studies & Research Lucknow Aligarh Muslim University, Allgarh (India) (India) (Internal Advisor) (External Advisor) DEPARTMENT OF BUSINESS ADMINISTRATION FACULTY OF MANAGEMENT STUDIES & RESEARCH ALIGARH MUSLIM UNIVERSITY ALIGARH (INDIA) 2008 ABSTRACT Introduction Civil Aviation represents one of the biggest industries worldwide with global airline revenues exceeding US$ 485 billion in 2007 (lATA, 2008b). The industry has moved towards liberalisation in the ownership of national carriers, capacity sharing, price controls and market access, leading to greater competition among airlines. In the de-regulated environment, the customer has many choices, if the first airline does not measure up-to the desired standards of service. Focus on service quality is the need of the hour if the airlines aspire to improve market share and further enhance financial perforniance in domestic and international markets. The airline industry has been a pioneer in the innovative use of Information Technology (IT) (Ghobrial & Trusilov, 2005). E-commerce and IT are changing the nature of the airline business. The dramatic growth of web and self-service technologies facilitate simplified passenger travel involving e-ticketing, automated check-in, common-user self-service kiosks and other passenger, services (Shon, Chen & Chang, 2003). Growth in the air traffic in recent years is due to the spread of low cost service. -
Word Thesis Template 2018
Light Controlled Cell-Cell Adhesions and Self-Sorting in Multicellular Structures Dissertation z ur Erlangung des Grades Doktor der Naturwissenschaften Am Fachbereich Biologie Der Johannes Gutenberg -Universität Mainz vorgelegt von Samaneh Rasoulinejad Geboren in Tehran, Iran Mainz, 2020 Page ii Date of oral examination: 02.12.2020 Page iii Declaration I hereby declare that I wrote the dissertation submitted without any unauthorized external assistance and used only sources acknowledged in this work. All textual passages which are appropriate verbatim or paraphrased from published and unpublished texts, as well as all information obtained from oral sources, are duly indicated and listed in accordance with bibliographical rules. In carrying out this research, I complied with the rules of standard scientific practice as formulated in the statutes of Johannes Gutenberg-University Mainz to ensure standard scientific practice. _____03.12.2020________ _________________________ Samaneh Rasoulinejad Page iv Page v Abstract The self-organizing of different cell types into multicellular structures and their organization into spatiotemporally controlled patterns are both challenging and extremely powerful to understand how cells function within tissues and for bottom-up tissue engineering. In this thesis, I demonstrated how two cells types can be independently controlled with blue and red light in order to control their self-assembly and self-sorting into distinct multicellular assemblies. For this purpose, different cell-cell interactions between the same or different cell types were developed such that they were individually triggerable with different colors of light, reversible in the dark and provided non-invasive and temporal control over the cell-cell adhesions. In multicellular mixtures, upon orthogonal photoactivation each cell type self-assembled independently and cells sorted out into separate assemblies based on specific self-recognition. -
(12) United States Patent (10) Patent No.: US 8,765,685 B2 B00kbinder Et Al
US008765685B2 (12) United States Patent (10) Patent No.: US 8,765,685 B2 B00kbinder et al. (45) Date of Patent: *Jul. 1, 2014 (54) METHODS FORTREATING EDEMABY (52) U.S. Cl. ADMINISTERING ASOLUBLE USPC .......................... 514/20.9; 514/21.2:435/201 HYALURONIDASE GLYCOPROTEIN (58) Field of Classification Search (SHASEGP) USPC ................................. 514/20.9, 21.2:435/201 See application file for complete search history. (75) Inventors: Louis Bookbinder, San Diego, CA (US); Anirban Kundu, San Diego, CA (56) References Cited (US); Gregory I. Frost, Del Mar, CA (US) U.S. PATENT DOCUMENTS 3,536,809 A 10/1970 AppleZweig .................... 424/28 (73) Assignee: Halozyme, Inc., San Diego, CA (US) 3,598,123 A 8, 1971 Zaffaroni ...................... 424/435 (*) Notice: Subject to any disclaimer, the term of this (Continued) patent is extended or adjusted under 35 U.S.C. 154(b) by 0 days. FOREIGN PATENT DOCUMENTS This patent is Subject to a terminal dis CA 1243,948 11, 1988 claimer. CA 23.18356 T 2000 (Continued) (21) Appl. No.: 13/506.783 OTHER PUBLICATIONS (22) Filed: May 16, 2012 Letter/Written Disclosure of the Information Disclosure Statement for the above-referenced application, mailed on Jul. 12, 2012, 3 (65) Prior Publication Data pageS. US 2012/O251620 A1 Oct. 4, 2012 (Continued) Primary Examiner — Rosanne Kosson Related U.S. Application Data (74) Attorney, Agent, or Firm — McKenna Long & Aldridge (60) Continuation of application No. 12/378.969, filed on LLP, Stephanie Seidman Feb. 20, 2009, now Pat. No. 8,202,517, which is a division of application No. 10/795,095, filed on Mar. -
Corporate Responsibility Report 2009 Summary Chief Executive’S Introduction Governance People and Community and People Customers
Corporate Responsibility Report 2009 Summary Chief Executive’s introduction Governance People and community Customers I believe corporate responsibility is good for business and it is good for Reed Elsevier. It means employing the highest ethical standards in everything we do and helping society by using our unique expertise to progress science and improve global health, advance the rule of law and prevent crime, and broaden access to information. Health and safety Corporate responsibility involves providing our customers with exceptional service and leading information and tools that enable them to make critical decisions, enhance productivity, and improve outcomes. It also means treating our employees fairly and inspiring them to reach their full potential, while making a significant contribution to the communities where we live and work. It requires us to further best practice in our supply chain, and limit our impact on the environment, while spurring knowledge and debate through Supply chain our environmental publications and expertise. In the pages that follow, you can find our 2009 corporate responsibility objectives, our performance against them, and future plans. We highlight progress, such as reaching our goal to train 80% of staff in our Code of Ethics and Business Conduct and indicate where we must take greater action, like reducing energy consumption at our data centres. The report details our emphasis on stakeholder engagement, our aim to lead by example, and our Environment support for initiatives that advance good corporate behaviour like the UN Global Compact with its ten core principles in human rights, labour, the environment, and anti-bribery. Despite challenging economic conditions in our markets, our commitment to corporate responsibility has not waned.