Mouse Anti-Trichomonas Vaginalis Monoclonal Antibody

SPECIFICATION SHEET Rev 110626MAB-C00158

Mouse Anti-Trichomonas vaginalis Monoclonal Antibody

Mouse, Monoclonal (Trichomonas vaginalis) Cat. No. DMAB4429 Lot. No. (See product label)

PRODUCT INFORMATION BACKGROUND

Product Overview: Monoclonal Antibody to Trichomonas Introduction: Trichomonas vaginalis is an anaerobic, flagellated vaginalis protozoan, a form of microorganism. The parasitic microorgan- Specificity: Trichomonas vaginalis ism is the causative agent of trichomoniasis, and is the most Isotype: IgG3 common pathogenic protozoan infection of humans in industrial- Clone: C986M ized countries. Infection rates between men and women are the Host animal: Mouse same with women showing symptoms while infections in men Immunogen: Disrupted Trichomonas vaginalis are usually asymptomatic. Transmission takes place directly Source: Ascites because the trophozoite does not have a cyst. The WHO has Format: Purified, Liquid estimated that 180 million cases of infection are acquired annu- Applications: Suitable for use in IFA and ELISA. Each laboratory ally worldwide. The estimates for North America alone are be- should determine an optimum working titer for use in its particular tween 5 and 8 million new infections each year, with an esti- application. Other applications have not been tested but use in mated rate of asymptomatic cases as high as 50%. Usually such assays should not necessarily be excluded. Recommended treatment consists of metronidazole and tinidazole. Trichomonas antibody pair for sandwich immunoassay: vaginalis is a protozoa which causes inflammation of the vaginal Capture Detection canal. It is considered to be a sexually transmitted disease. DMAB4429 DMAB4431 Keywords: T vaginalis ; TV ; Trichomonas vaginalis; Eukarya; Purification: >90% pure. Protein A chromatography Metamonada; Parabasalia; Trichomonadida; Trichomonas; T. Affinity Constant: Not determined vaginalis

PACKAGING REFERENCES Concentration: Lot specific (OD280nm, E0.1% = 1.3) 1. Soper, D (2004). "Trichomoniasis: under control or undercon- Buffer: 0.01M PBS, pH 7.2 trolled?". American Journal of Obstetrics and Gynecology 190 Preservative: 0.1% Sodium azide (1): 281–90. Storage: Short term (up to 2 weeks) store at 2-8°C. Long term, 2. Hook, Edward W. (1999). "Trichomonas vaginalis-No Longer aliquot and store at -20°C. Avoid multiple freeze/thaw cycles A Minor STD". Sexually Transmitted Diseases 26 (7): 388–9. Warning: This product contains sodium azide, which has been 3. Ohlemeyer, C; Hornberger, L; Lynch, D; Swierkosz, E (March classified as Xn (Harmful) in European Directive 67/548/EEC in 1998). "Diagnosis of Trichomonas vaginalis in adolescent fe- the concentration range of 0.1–1.0%. When disposing of this males: InPouch TV® culture versus wet-mount microscopy". reagent through lead or coppe plumbing, flush with copious vol- Journal of Adolescent Health 22 (3): 205–8. umes of water to prevent azide build-up in drains.

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