Research Topics Key Words Researcher Reseach Field Field Of

Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Basic Biology

Biology Molecular analysis of cellular responses to DNA damage Functional analysis of DDB complex in cellular responses to DNA Heredity/genome DNA repair Hereditary disorder Cancer Signal transduction MATSUNAGA Research on anti-cancer drugs targeting damage dynamics Cellular response Ultraviolet light Tsukasa cellular responses to DNA damage Establishment and application of detection systems for UV-induced DNA damage

Evolution of dicyemid mesozoans and their strategy to parasitism Molecular evolutionary strategies in protists Heredity/genome Evolutionary protistology, Parasitism, Differentiation of Life cycle of the dinoflagellates and their phylogenetic position HIGASHI Hiroshi dynamics mitochondria Nuclear apoptosis in Tetrahymena thermophila Cellulolysis by the protozoan Tetrahymena

Cancer Research Heredity/genome Study for genomics in liver Liver metabolism and systemic illness Experimental Pathology, Virology, Cancer, Liver KANEKO Shuichi dynamics Hepatitis Virus

Analysis of Regulatory Mechanism of Wound-Responsive Gene in Global gene expression analysis using Higher Plants Heredity/genome Plant stress response, transcription factor, plant defense microarray Study on mechanism of action of trichothecene phytotoxin in higher NISHIUCHI Takumi dynamics response Proteome analysis plants Functional analysis of transcription factors in plant stress response.

DNA analysis in the study for carcinogenesis of Endometrial cancer Development of hormone-drug release and gene therapy Heredity/genome Molecular pathology in gynecologic field Auti-Cancen system via supramolecular dissociation Human papilloma analysis in the carcinogenesis of uterine cervical INOUE Masaki dynamics chemotherapy in Gynecologic field Cell aging and carcinogenesis cancer Gene therapy for ovarian Cancer

Heredity/genome Characterization of autism-associated genes on human X HORIKE Shinichi dynamics chromosome

Heredity/genome Regulatory System of Cell Cycle in Eukaryote Regulation of Cell Cycle, Yeast Genetics, Molecular Biology HAYASHI Naoyuki dynamics

Study on structure and physiological role of calcitonin in marine invertebrates and vertebrates (particularly fish) Effect of physical stimuli and bioactive substances on the bone Ecology/environment Effects of heavy metal and endocrine- Calcium metabolism, Bone metabolism, Gravity, Micro-gravity SUZUKI Nobuo metabolism: analysis by the culture system of fish scales disrupting chemical on bone metabolism Effect of heavy metal and endocrine-disrupting chemical on bone metabolism

Ecology/environment Ecology of freshwater zooplankters KAWABATA Keiichi Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Basic Biology Biology Pest control of Agro-forestry pests Insect Population Dynamics in the Tropics Ecology/environment Ecology of tropical insects Population Dynamics of Phytophagous Insects Ecology Environmental Preservation Plant Protection NAKAMURA Koji Conservation of Satoyama Conservation Satoyama Ecosystems

Social parasitic behaviour in Vollenhoivia nipponica Clonal reproduction and caste determination in ant, Vollenhovia Ecology/environment Biology in insects and birds emeryi. Behaviour, Evolution, Sociality, interaction, ant, bird OKAWARA Kyosuke Mutualistic interactions between ants and plants with fruits and seeds Ecological study for the conservation of waterfowl in Katano Kamoike

Underground Organ of Herbaceous Angiosperms UMEBAYASHI Ecology/environment Seedlings of woodyplants in Japan Masayoshi

Ecology/environment Ecolution of Sex Chage Ecology KINOSHITA Eiichiro

Host Preference of mosquito vectors Chemical analysis of larval diet of African malaria vectors, Anopheles Vector Ecology. Tropics. malaria. Japanese encephalitis. dengue Ecology/environment TUNO Nobuko gambiae complex fever. biological control Siginificance of Mushroom Posion

Plant Study on Structure and Expression of Plant Genes Botany,Biological Education YAKURA Kimitaka physiology/molecule Studies on Biological Education

Plant Molecular mechanism of anhydrobiosis in the terrestrial Production of UV absorbing pigments Stress Physiology, Photosynthesis SAKAMOTO Toshio physiology/molecule cyanobacterium

Analysis of Regulatory Mechanism of Wound-Responsive Gene in Global gene expression analysis using Higher Plants Plant Plant stress response, transcription factor, plant defense microarray Study on mechanism of action of trichothecene phytotoxin in higher NISHIUCHI Takumi physiology/molecule response Proteome analysis plants Functional analysis of transcription factors in plant stress response.

Study on structure and physiological role of calcitonin in marine invertebrates and vertebrates (particularly fish) Effect of physical stimuli and bioactive substances on the bone Form/structure Effects of heavy metal and endocrine- Calcium metabolism, Bone metabolism, Gravity, Micro-gravity SUZUKI Nobuo metabolism: analysis by the culture system of fish scales disrupting chemical on bone metabolism Effect of heavy metal and endocrine-disrupting chemical on bone metabolism

Underground Organ of Herbaceous Angiosperms UMEBAYASHI Form/structure Seedlings of woodyplants in Japan Masayoshi Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Basic Biology

Biology Endocrine Control of Insect Growth and Development Molecular cloning and structure analysis of bombyxin, an insect gene, brain, biotechnology, hormone, silkworm moth IWAMI Masafumi insulin-related peptide, gene Molecular Studies on Insect Molting and Metamorphosis

Neural and molecular mechanisms of pheromone information Animal processing in the silkworm Silkworm insect pheromone KIYA Taketoshi physiology/behavior Molecular mechanisms of juvenile hormone synthesis Neural basis for the dance communication of the honeybees

Study on structure and physiological role of calcitonin in marine invertebrates and vertebrates (particularly fish) Animal Effect of physical stimuli and bioactive substances on the bone Effects of heavy metal and endocrine- Calcium metabolism, Bone metabolism, Gravity, Micro-gravity SUZUKI Nobuo physiology/behavior metabolism: analysis by the culture system of fish scales disrupting chemical on bone metabolism Effect of heavy metal and endocrine-disrupting chemical on bone metabolism

Origin of Angiosperms inferred from the evolutionary processes of Living organisms outer integument and endsperm Morphology, Evolution, EvoDevo YAMADA Toshihiro diversity/classification Evolutionary process of angiosperms' synapomorphies in ovule and its implications for angiosperm origin

Evolution of morphogenesis in land plants Living organisms Evolution of reproductive organs in gametophyte generation in land evolution, morphogenesis, Physcomitrella patens KOFUJI Rumiko diversity/classification plants Study of gene expression patterns in amphidiploid species

Living organisms Underground Organ of Herbaceous Angiosperms UMEBAYASHI diversity/classification Seedlings of woodyplants in Japan Masayoshi

Living organisms Ecolution of Sex Chage Ecology KINOSHITA Eiichiro diversity/classification Biological Science Structure and Function of nano-size magnetosome FUKUMORI Structural biochemistry Development of Heavy Metal Adsorbent Structure and Function of Giant Hemoglobin Yoshihiro Symbiosis of Pogonophore with bacteria

Mechanism and consequences of phagocytic removal of altered own apoptosis, phagocytosis, self defense, innate immunity, infectious NAKANISHI Functional biochemistry cells disease Yoshinobu Mechanism of prevention of infectious diseases by innate immunity

Undifferenticated property maintenance mechanism of embryo-stem Functional biochemistry YOKOTA Takashi cells (ES cells, self-replication, STAT3)

Functional analysis of carbohydrates using glycosyltransferase Drug development targeting carbohydrates knockout mice Functional biochemistry Development of animal models for human Epigenetic regulation of mammalian development Manipulating the Mouse Embryo, Glycobiology, Epigenetics ASANO Masahide diseases by transgenic technology Development of animal model for human disease using embryo manipulating technology Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Biology Biological Science Biological Molecular mechanism of anhydrobiosis in the terrestrial Functional biochemistry Production of UV absorbing pigments Stress Physiology, Photosynthesis SAKAMOTO Toshio cyanobacterium

Reaction mechanism of ferredoxin-NADPH oxidoreductase from gram positive bacteria Functional biochemistry Iron sulfur type photosynthetic reaction center from photosyntetic phototrophic bacteria, electron transfer, kinetics SEO Daisuke bacteria Investigation of Fd-dependent oxidoreductases in bacteria

Molecular mechanisms for magnetic organelle 'magnetosome' of Prokaryotic organelle, Bacterial cytoskeleton, Magnetotactic Functional biochemistry TAOKA Azuma magnetotactic bacnteria Bacteria, Magnetosome

Molecular Basis of the Alzheimer's disease Diabetic Angiopathy, Advanced Glycation Endproducts, Receptor pathogenesis and prevention/treatment of Functional biochemistry Signal transduction through protein phosphatases for advanced glycation endproducts, RAGE, Angiogenesis, WATANABE Takuo diabetic angiopathy Molecular mechanism of diabetic angiopathy Alzheimer's disease,

molecular mechanism of sel-renewal in embryonic stem cells Functional biochemistry KOIDE Hiroshi oncogene

Study on the mechanism for exclusion of apoptotic cells by phagocytes phagocytosis, apoptosis,innate immunity, infection immunity, Functional biochemistry Study on the mammalian spermatogenic pathway HIRAYAMA Akiko bacteria, virus, spermatogenesis phagocytic clearance of microbes in innate immunity

Development of effective diagnosis and therapy for metastatic cancer Development of effective diagnosis and Development of angiogenesis inhibitors as an anticancer drug Cancer chemotherapy nucleoside metabolism Cancer Functional biochemistry therapy for metastatic cancer ENDO Yoshio Mechanisms of antitumor action and resistance to antitumor Chemotherapy metastasis angiogenesis Mechanisms of antitumor nucleosides nucleosides

Structure and Function of nano-size magnetosome FUKUMORI Functional biochemistry Development of Heavy Metal Adsorbent Structure and Function of Giant Hemoglobin Yoshihiro Symbiosis of Pogonophore with bacteria

Modification of the function of bilirubin Transformation of NOx by Enzymes oxidase Function of Multicopper Oxidases and Their Alterations by Mutation Functional biochemistry metalloprotein, bioinorganic chemistry, Protein engineering SAKURAI Takeshi Biotechnology of lacquer latex and Application to Biofuel Cell Biofuel cell Enzyme Chemistry of Lacquer Latex

Protein engineering of metalloproteins Elucidation and application of the microbial Biochemistry, Molecular Biology, Protein engineering, KATAOKA Functional biochemistry Studies on structures and functions of multi-metal containing proteins denitrification mechanism. Metalloproteins Kunishige Studies on structures and functions of amino acid dehydrogenases

Study on the Regulation of Activity of Cyclin-Dependent Kinases Studies on the Regulation of M Phase in Human Cells YAMASHITA Functional biochemistry Screening of checkpoint abrogators Cell Cycle Control Studies on the Mechanism of DNA Damage Checkpoint in Human Katsumi Cells Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Biology Science Biological Angiogenesis Functional biochemistry Diabetic angiopathy vascular biology, diabetes YAMAMOTO Hiroshi Functional genomics

Development and Biological Application of High-speed Atomic Force Development of high-speed scanning Microscopy motor proteins, single-molecule analysis, Atomic Force Biophysics ANDO Toshio probe microscopies Study on Motor Proteins Microscope Awards

Reaction mechanism of ferredoxin-NADPH oxidoreductase from gram positive bacteria Biophysics Iron sulfur type photosynthetic reaction center from photosyntetic phototrophic bacteria, electron transfer, kinetics SEO Daisuke bacteria Investigation of Fd-dependent oxidoreductases in bacteria

Development of high-speed atromic force microscope for biological UCHIHASHI Biophysics system Takayuki

Isolation of proteins which are responsible for brain function Analysis of genes and proteins which were Studies on molecular mechanisms of brain dysfunction Biophysics Hygiene Neuro chemistry Molecular Biology SAIJO Kiyofumi responded to environmental change Alteration in signal transduction by aging and subsequent carcinogenesis

Undifferenticated property maintenance mechanism of embryo-stem Molecular biology YOKOTA Takashi cells (ES cells, self-replication, STAT3)

Identification of novel molecular targets Identification of novel cancer genes using retroviral insertional Molecular biology Tumor virus, Oncogene, Genome informatics SUZUKI Takeshi that interact with cancer genes mutagenesis

Substrate recognition mechanism of molecular chaperones and ATP- Molecular biology stress response, molecular chaperone, ATP-dependent protease KANEMORI Masaaki dependent protea

Health effect of KOSA bio-aerosol Molecular biology Relationship analysis of SNPs and cancer Cancer Molecular Biology Sing SNP HIGASHI Tomomi Functional analysis of TGF-b binding protein

molecular mechanism of sel-renewal in embryonic stem cells Molecular biology KOIDE Hiroshi oncogene

Glutamate signaling in bone Exhaustive search and functional analysis of bone-derived secreted Molecular biology molecules. HINOI Eiichi Research for elucidation of regulatory mechanisms of osteoblasts function by Clock genes. Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Biology Science Biological Development of a body map of human genome methylation Molecular biology computational identification of useful knowledge from gene expression YAMADA Yoichi data

Molecular biology Methylation abnormality of cancer-related genes in pancreatic fluid Clinical OncologyGastroenterology OTSUBO Koshiro

Molecular biology Cellular Signal transduction pathways involved in stress response Radiation Biol. and Toxicology Cell Biology Molecular Biology YAMAMOTO Kenichi

Molecular biology Molecular Biology of hepatitis B viruses Molecular Biology Virology KUROKI Kazuyuki

Roles of ADAMTS family genes in organogenesis and organ function Molecular biology Extracellular matrix metabolism and disorders KUNO Koji Extracellular matrix metabolism and cancer invasion-metastasis

Molecular biology Structure and function of U13 snoRNA. small nucleolar RNA, snoRNA, ribosomal RNA KIDO Yukiharu

Study on physiological role of Fas ligand Molecular biology Study on Physiological Connection between Apoptosis and IMAMURA Ryu Inflammation

Molecular biology Multiple roles for innate immunity apoptosis, inflammation, innate-immunity KINOSHITA Takeshi

KOBAYASHI Molecular biology study on DNA damage repair Masahiko

Analysis of Regulatory Mechanism of Wound-Responsive Gene in Global gene expression analysis using Higher Plants Plant stress response, transcription factor, plant defense Molecular biology microarray Study on mechanism of action of trichothecene phytotoxin in higher NISHIUCHI Takumi response Proteome analysis plants Functional analysis of transcription factors in plant stress response.

Molecular biology Study of neural development in Drosophila neural development transcription factor Drosophila melanogaster KOIZUMI Keita

Endocrine Control of Insect Growth and Development Molecular cloning and structure analysis of bombyxin, an insect Molecular biology gene, brain, biotechnology, hormone, silkworm moth IWAMI Masafumi insulin-related peptide, gene Molecular Studies on Insect Molting and Metamorphosis Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Biology Science Biological Tissue regeneration regulation and regeneration discontinuation NAKAMURA Molecular biology mechanism via the HGF-Met system Takahiro

Protein engineering of metalloproteins Elucidation and application of the microbial Biochemistry, Molecular Biology, Protein engineering, KATAOKA Molecular biology Studies on structures and functions of multi-metal containing proteins denitrification mechanism. Metalloproteins Kunishige Studies on structures and functions of amino acid dehydrogenases

Isolation of proteins which are responsible for brain function Analysis of genes and proteins which were Studies on molecular mechanisms of brain dysfunction Molecular biology Hygiene Neuro chemistry Molecular Biology SAIJO Kiyofumi responded to environmental change Alteration in signal transduction by aging and subsequent carcinogenesis

Molecular Mechanisms regulating Therapeutic Resistance in Cancer Stem Cells Cancer stem cells, Cancer-microenvironment, Hematopoietic Molecular biology NAKA Kazuhito Therapeutic-resistant CML stem cells Maintenance of Self-renewal Ability in Hematopoietic Stem Cells stem cells

Study on the Regulation of Activity of Cyclin-Dependent Kinases Studies on the Regulation of M Phase in Human Cells YAMASHITA Molecular biology Screening of checkpoint abrogators Cell Cycle Control Studies on the Mechanism of DNA Damage Checkpoint in Human Katsumi Cells

Study on MAP kinase cascade Regulation of cell proliferation and Molecular biology Study on scaffold proteins for mammalian MAP kinase cascades cell siganling, cell differentiation, neural development YOSHIOKA Katsuji apoptosis by MAPK cascades Study on neurogenesis

Molecular biology Regulatory System of Cell Cycle in Eukaryote Regulation of Cell Cycle, Yeast Genetics, Molecular Biology HAYASHI Naoyuki

Localization of biological active proteins in Histochemical study on signaling in development, growth and Cell biology histochemistry, cell, tissue, differentiation ISEKI Shoichi living cells and tissues differentiation

Identification of novel molecular targets Identification of novel cancer genes using retroviral insertional Cell biology Tumor virus, Oncogene, Genome informatics SUZUKI Takeshi that interact with cancer genes mutagenesis

Study on Structure and Expression of Plant Genes Cell biology Botany,Biological Education YAKURA Kimitaka Studies on Biological Education

Study on the Temporo mardibular Joint Disease, basically and Etilology or treatment strategy on TAKATSUKA Cell biology clinically Oral Surgery temporomandibular disorders Shigeyuki Oral surgery

Health effect of KOSA bio-aerosol Cell biology Relationship analysis of SNPs and cancer Cancer Molecular Biology Sing SNP HIGASHI Tomomi Functional analysis of TGF-b binding protein Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Biology Science Biological Study of Growth Factors in the Testis and Epididymis WAKAYAMA Cell biology Anatomy Study of Adhesion Molecule in the Spermatogenesis Tomohiko

Glutamate signaling in bone Exhaustive search and functional analysis of bone-derived secreted Cell biology molecules. HINOI Eiichi Research for elucidation of regulatory mechanisms of osteoblasts function by Clock genes.

Cell biology Cellular Signal transduction pathways involved in stress response Radiation Biol. and Toxicology Cell Biology Molecular Biology YAMAMOTO Kenichi

Development of effective diagnosis and therapy for metastatic cancer Development of effective diagnosis and Development of angiogenesis inhibitors as an anticancer drug Cancer chemotherapy nucleoside metabolism Cancer Cell biology therapy for metastatic cancer ENDO Yoshio Mechanisms of antitumor action and resistance to antitumor Chemotherapy metastasis angiogenesis Mechanisms of antitumor nucleosides nucleosides

Cell biology Multiple roles for innate immunity apoptosis, inflammation, innate-immunity KINOSHITA Takeshi

KOBAYASHI Cell biology study on DNA damage repair Masahiko

Structure and Function of nano-size magnetosome FUKUMORI Cell biology Development of Heavy Metal Adsorbent Structure and Function of Giant Hemoglobin Yoshihiro Symbiosis of Pogonophore with bacteria

Study on the Regulation of Activity of Cyclin-Dependent Kinases Studies on the Regulation of M Phase in Human Cells YAMASHITA Cell biology Screening of checkpoint abrogators Cell Cycle Control Studies on the Mechanism of DNA Damage Checkpoint in Human Katsumi Cells

Study on MAP kinase cascade Regulation of cell proliferation and Cell biology Study on scaffold proteins for mammalian MAP kinase cascades cell siganling, cell differentiation, neural development YOSHIOKA Katsuji apoptosis by MAPK cascades Study on neurogenesis

Cell biology Regulatory System of Cell Cycle in Eukaryote Regulation of Cell Cycle, Yeast Genetics, Molecular Biology HAYASHI Naoyuki

Cell biology Developmental Biology, Immunological Biology AMANO Shigetoyo Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration

Biology Science Biological Functional analysis of carbohydrates using glycosyltransferase Drug development targeting carbohydrates knockout mice Developmental biology Development of animal models for human Epigenetic regulation of mammalian development Manipulating the Mouse Embryo, Glycobiology, Epigenetics ASANO Masahide diseases by transgenic technology Development of animal model for human disease using embryo manipulating technology

Animal-vegetal polarity of sea urchin eggs Developmental biology of sea urchins, Evolutionary YAMAGUCHI Developmental biology Evolution of echinoderms developmental biology, Deuterostomes Masaaki

molecular mechanism of sel-renewal in embryonic stem cells Developmental biology KOIDE Hiroshi oncogene

Glutamate signaling in bone Exhaustive search and functional analysis of bone-derived secreted Developmental biology molecules. HINOI Eiichi Research for elucidation of regulatory mechanisms of osteoblasts function by Clock genes.

Developmental biology Study of neural development in Drosophila neural development transcription factor Drosophila melanogaster KOIZUMI Keita

Developmental biology Developmental Biology, Immunological Biology AMANO Shigetoyo

Animal-vegetal polarity of sea urchin eggs Developmental biology of sea urchins, Evolutionary YAMAGUCHI Evolutionary biology Evolution of echinoderms developmental biology, Deuterostomes Masaaki

Social parasitic behaviour in Vollenhoivia nipponica Clonal reproduction and caste determination in ant, Vollenhovia Evolutionary biology Biology in insects and birds emeryi. Behaviour, Evolution, Sociality, interaction, ant, bird OKAWARA Kyosuke Mutualistic interactions between ants and plants with fruits and seeds Ecological study for the conservation of waterfowl in Katano Kamoike

Evolution of morphogenesis in land plants Evolution of reproductive organs in gametophyte generation in land Evolutionary biology evolution, morphogenesis, Physcomitrella patens KOFUJI Rumiko plants Study of gene expression patterns in amphidiploid species

Evolution of dicyemid mesozoans and their strategy to parasitism Molecular evolutionary strategies in protists Evolutionary protistology, Parasitism, Differentiation of Evolutionary biology Life cycle of the dinoflagellates and their phylogenetic position HIGASHI Hiroshi mitochondria Nuclear apoptosis in Tetrahymena thermophila Cellulolysis by the protozoan Tetrahymena

NISHIYAMA Evolutionary biology Investigation of Early Land Plant Evolution by Comparative Genomics Tomoaki Research themes under Reseach Field Field of expertise Research topics Key words Researcher consideration Anthropology

Biology the study of body composition and lifestyle-related disease A study of fall-prevention and establishment of functional recovery Physiological system Physical Education statistics Public Health Sports science DEMURA Shinichi anthropology A study of objectivization mesurment and evaluation of muscle strength and controlled force exertion