molecules Review Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments Rusin Zhao 1 , Ruijia Yang 1, Paul R. Cooper 1, Zohaib Khurshid 2 , Amin Shavandi 3 and Jithendra Ratnayake 1,* 1 Department of Oral Science, Faculty of Dentistry, University of Otago, 310 Great King Street, Dunedin 9016, New Zealand;
[email protected] (R.Z.);
[email protected] (R.Y.);
[email protected] (P.R.C.) 2 Department of Prosthodontics and Dental Implantology, College of Dentistry, King Faisal University, Al-Ahsa 31982, Saudi Arabia;
[email protected] 3 BioMatter Unit—École Polytechnique de Bruxelles, Université Libre de Bruxelles (ULB), Avenue F.D. Roosevelt, 50—CP 165/61, 1050 Brussels, Belgium;
[email protected] * Correspondence:
[email protected]; Tel.: +022-122-8304 Abstract: After tooth loss, bone resorption is irreversible, leaving the area without adequate bone volume for successful implant treatment. Bone grafting is the only solution to reverse dental bone loss and is a well-accepted procedure required in one in every four dental implants. Research and development in materials, design and fabrication technologies have expanded over the years to achieve successful and long-lasting dental implants for tooth substitution. This review will critically present the various dental bone graft and substitute materials that have been used to achieve a successful dental implant. The article also reviews the properties of dental bone grafts and various dental bone substitutes that have been studied or are currently available commercially. The various classifications of bone grafts and substitutes, including natural and synthetic materials, are Citation: Zhao, R.; Yang, R.; Cooper, critically presented, and available commercial products in each category are discussed.