Signature Signature extracts Organic extract

Healthy for muscle mass

Hydrolyzed vegetable proteins from pea, rice, wheat and sesame High source of peptides & essential amino acids Excellent digestibility Why choose our hydrolyzed vegetable proteins?

The vegetable solution for sports nutrition Prothy™ products are a unique line of hydrolyzed vegetable proteins with up to 80% polypeptides and provide all the benefits sought after by athletes: • Easy to digest nutrients • Increases anabolism to develop muscle mass & strength • Improves recovery after exercise and diminishes muscle soreness • Decreases catabolism to avoid muscle loss

Prothy™ hydrolyzed protein products offer low molecular weight (1) Cumulative distribution of molecular weights Cumulative distribution of molecularProthy™ weights: Prothy hydrolyzed hydrolyzed proteins*, proteins* intact proteins* versus and soya isolatenon-hydrolyzed proteins proteins* and soy isolate protein % 100 80 Prothy™ low molecular weight: 60 up to 92% < 3.5 kDa** 40 versus 28% 20 for soy isolate protein 0 kDa <0,2 <0,5 <1,5 <2,5 <3,5 <4,5

Prothy products* Non-hydrolyzed proteins* Soy isolate protein * average of rice, pea, sesame and wheat proteins molecular weights ** obtained with Prothy™ Pea

A valuable source of amino acids Did you know?

Prothy™ products offer up to: Essential amino acids (AA) cannot be synthesized and • 80% polypeptides must be provided from the • 18% Branched Chain Amino Acids (BCAAs ) diet. BCAAs (isoleucine, • Three times more than whey leucine & valine) account • Twice as much compared to whey for 35% of the essential composition (% / total AA) (1) amino acids in muscle proteins and are important Arginine for post-exercise muscle protein synthesis. Glutamic acid Arginine is an essential

Total BCAAs AA for growth and intense exercise. Leucine Glutamic acid or gluta-

Isoleucine mine is a source of energy for muscles during stress Valine which supports physical

0 5 10 15 20 25 30 35 40 effort and immune system

Prothy Sesame Prothy Wheat Prothy Pea Prothy Rice Soy isolate protein efficiency. Benefits of hydrolyzed proteins have been demonstrated in numerous clinical trials compared to non-hydrolyzed proteins or free form of amino acids. Hydrolyzed proteins accelerate protein digestion and augment amino acid availability: Plasma amino acid concentrations are increased by 25–50% compared to non-hydrolyzed proteins(2)

Gain of enzymatic degradability after 1 hour (1) Enzymatic degradability after 1 hour (1) Gain of degradability (1 hour) ProthyProthy™™ hydrolyzedhydolysates vs proteinsintact proteins versus (Enzymatic non-hydrolyzed degradability) proteins Prothy™Enzymatic Pea versus degradability soy (1 isolate hour) protein % % 80 60 +57% 70 + 29% degradability 50 +46% versus soy isolate 60

40 +36% 50 +31% 30 40

30 20 20 10 10

0 0 Prothy Rice Prothy Pea Prothy Wheat Prothy Sesame Prothy Pea Soy isolate

High digestibility of Prothy™ products allows rapid bioavailability

Hydrolyzed proteins enable a better skeletal muscle protein synthesis : A 35 g dose of rapidly absorbed hydrolyzed protein is ~30% more effective in stimulating skeletal muscle protein synthesis versus non-hydrolyzed protein when measured over the 6 hours period (2) (3) When ingested after exercise, hydrolyzed proteins enhance recovery of force-generating muscle capacity by speeding up tissue repair(4)

(1) Analysis performed by a third party. (2) Koopman R et al. Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein. Am J Clin Nutr 2009; 90(1):106-115. (3) Manninen, Anssi H. Review: Protein hydrolysates in sports nutrition. Nutrition & Metabolism 2009, 6:38. (4) Buckley JD et al. Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise. Sci Med Sport 2010; 13(1):178-181. The healthy choice !

, perfect for sports nutrition

High protein content, up to 80% Rich in all essential and semi-essential amino acids, including branched chain amino acids (BCAAs) Predigested proteins to rapidly develop muscle mass (anabolic properties) and reduce muscle damage (anti-catabolic properties)

Organic ✓ Non-GMO ✓ Lactose-free ✓ Isoflavone-free grade available ✓ Hypoallergenic* ✓ Gluten-free**

* Hydrolysis lowers risk of allergenicity. ** Except Prothy™ Wheat.

Nexira is a world leader in the manufacturing of high Reliable methods of analysis guarantee to our quality natural ingredients. Thanks to our expertise customers the quality and the origin of our range of in extraction and purification, we work every day ingredients. to expand our portfolio of botanical extracts and to bring new standardizations to the market. Made in France

Our expertise in sustainable sourcing, our control by of gentle manufacturing processes in our 5 facilities located in France as well as our extensive R&D enable us to offer highly potent ingredients.

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