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Markers of Self-Renewal and Differentiation

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Markers of Self-Renewal and Differentiation BD Stem Cell Resource Markers of Self-Renewal and Differentiation 23-9953-00 Green colored markers are available from BD Biosciences Liver Thymus Green colored markers are available from BD Biosciences Embryonic Stem Cell TGF Beta Signaling Oligodendrocyte Self Renewing Pathway Heart - cardiogenesis Hemangioblast Positve Markers Intracellular (continued) Surface Surface Surface Sperm Intracellular Surface NF-Ya BMPR-II CD44 α-Actinin ACE Alkaline Phosphatase BMP-SMad TGF-β/Activin Runx1 (CBFA2) IFN-γ Receptor, β Chain CD44H (Pgp-1, H-CAM) Wnt Annexin V CD31 (PECAM-1) CCR4 Erk-MAPK Egg SCL (Tal1) Intracellular CD140a (PDGF receptor α chain) JAK-STAT Annexin VI CD34 CD9 Wnt TGF-β/Activin WASP (Wiskott-Aldrich c-Myc Skin and hair BMP4 bFGF CD15 (SSEA-1, Lewis x) Galactocerebroside C LIF N-Cadherin CD133 (AC133, Prominin-1) Syndrome Protein) DP-1 CD24 O1 LIFR gp130 Cardiac Troponin CD144 (VE-Cadherin) Negative Marker Surface E2F-1 CD29 (Integrin β1) O4 Cardiac-specific myosin CD202b (TIE2) CD2 E2F-2 Intracellular CD30 Caveolin-2 CD309 (Flk1, KDR, Ly-73, VEGFR2) CD3 E2F-3 MBP CD4 CD49f (Integrin 6) Caveolin-3 CD324 (E-Cadherin) α Id1 Intestine CD10 Olig1 CD325 (MCAD) CD133 (AC133, Prominin-1) Pancreas EphB4 CD13 Id2 Olig2 CD324 (E-Cadherin) p Desmin Podocalyxin CD14 Id3 RIP p p Jak Smads GATA4 Intracellular CD15 (SSEA-1, Lewis x) CDw338 (ABCG2) p107 β-catenin MEK/ERK Neuron-restricted progenitor 1/5 GATA6 Brachyury CD15s (Sialyl, Lewis x) Frizzled-5 p16 INK4 Intracellular Stat3 Smads CD16 GCTM-2 Oct4 Nanog HAND1 GATA1 p300 Map2 C-myc Sox2 2/3 CD19 Podocalyxin HAND2 LMO-2 PP2A Nestin CD20 SSEA-3 Myogenin Runx1 (CBFA2) CD24 ROCK-I β III Tubulin (TUJ1) Primordial Germ Cell SSEA-4 Self Renewal NF-YA Tal (SCL) CD33 ROCK-II Neuron Nkx2.5 Endothelial cell CD36 TRA-1-60 Antigen Smad2/3 Surface Surface Surface CD38 TRA-1-81 Antigen Smad4 CD24 Definitive CD45 CD31 (PECAM-1) CD14 Secreted SP1 CD56 (NCAM) CD45R CD34 CD15 (SSEA-1, Lewis x) Cripto Wnt Signaling CD81 (TAPA-1) CD48 Endoderm CD66 CD18 CD56 (NCAM) FGF-4 Secreted CD90 (Thy-1) Embryonic Stem Cell Lung CD66c CD29 (Integrin β1) CD97 GDF-3 Wnt16 CD90.1 (Thy-1.1) Thyroid Intracellular CD106 (VCAM-1) CD31 (PECAM-1) CD114 (G-CSF Receptor) Lefty-A CD90.2 (Thy-1.2) 14-3-3 or Induced Pluripotent CD117 (SCF R, c-kit) CD34 CD138 (Syndecan-1) SFRP2 CD112 14-3-3ε CD166 (ALCAM) CD36 Negative Markers Intracellular Intracellular CD271 (NGF Receptor) Neural Crest Casein Kinase II α/α CD202b (TIE2) CD45 GATA3 c-Myc Contactin Stem Cell Stem Cell Casein Kinase II β CD309 (Flk1, KDR, Ly-73, VEGFR2) CD45R Hematopoietic DPPA4 GABA A Receptor Casein Kinase Iε Ectoderm Connexin-43 CD49d (Integrin α4) Lineage Markers DPPA5 (ESG1) GABA B Receptor α-Catenin VE-Cadherin CD49e (Integrin α5) Monoblast FoxD3 GAP-43 (Neuromodulin) β-Catenin CD49f (Integrin α6) Surface GCNF (NR6A1) GluR δ 2 Mesenchymal stem cell β-Catenin (pS45) CD54 (ICAM-1) CD11c Hsp27 GluR2 (from bone marrow) γ-Catenin CD13 LIN-28 GluR4 Positive Markers Surface CD56 (NCAM) δ-Catenin CD15 (SSEA-1, Lewis x) Nanog GluR5/6/7 CD10 CD62E (E-selectin) CBP (CREB-Binding Protein) CD33 Oct3/4 p-Glycoprotein CD13 CD62L (L-selectin) GSK-3β Neural Heart CD115 PRC2 (Suz12) Jagged1 CD14 CD62P (P-selectin) GSK-3β (pY216) CD116 (GM-CSF Receptor) Rex-1 mGluR1 CD15 (SSEA-1, Lewis x) CD92 HDAC3 Neurons, Glia Megakaryoblast SMAD2 mGluR1 Stem Cell CD29 (Integrin β1) CD93 (C1qRp) PP2A Catalytic α α Surface Sox2 Smooth Muscle CD31 (PECAM-1) CDw93 Ectoderm Neuroglycan C CD34 STAT3 Neuropilin-2 CD44H (Pgp-1, H-CAM) CD102 (ICAM-2) Early ectoderm Cardiac Tissue CD36 STAT3 (pS727) Nicastrin CD49d (Integrin α4) CD105 (Endoglin) Surface CD41 STAT3 (pY705) Chondrocytes CD49e (Integrin α5) CD106 (VCAM-1) Notch1 Serotonin Receptor 5-HT 2AR CD61 STAT3-interacting protein 1 Serotonin Receptor 5-HT 2BR Osteocytes CD51 CD109 Intracellular HLA-DR UTF-1 TrkB CD54 (ICAM-1) CD112 Nestin Proerythroblast Zic3 Secreted CD71 (Transferrin Receptor) CD116 (GM-CSF Receptor) TP63 (TP73L) Surface ApoE CD73 CD117 (SCF R, c-kit) Induced Pluripotency Skin Precursor CD71 (Transferrin Receptor) Intracellular Intracellular CD90 (Thy-1) CD120a Surface Skeletal Muscle CD105 (Endoglin) KLF4 N-Cadherin Kidney CD105 (Endoglin) CD120b Sca-1 PU.1 Lin28 ChAT CD106 (VCAM-1) CD121a (IL-1 Receptor) Fibronectin Glial Restricted Ter 119 c-myc Intracellular Doublecortin CD117 (SCF R, c-kit) CD124 (IL-4 Receptor α) Progenitor Myeloblast GAD65 Nanog CRABP2 CD120a CD141 (Thrombomodulin) Surface Glutamine Synthetase Mesoderm Oct3/4 Nestin Mesenchymal CD120b CD144 (VE-Cadherin) CD13 MAP2 (a+b) Sox2 Vimentin CD166 (ALCAM) CDw145 CD15 (SSEA-1, Lewis x) MAP2B Trophoblast Neural Stem Cell CD271 (NGF Receptor) CD146 (MCAM, MUC18) CD33 Surface MASH1 Stem Cell Surface CD309 (Flk1, KDR, Ly-73, VEGFR2) CD147 (Neurothelin) CD91 A2B5 Nestin Cytokeratin 7 Neuronal CD318 (CDCP1) CD151 CD114 (G-CSF Receptor) CD15 (SSEA-1, Lewis x) Neurofilament NF-H Trop-1 Ly-6A/E (Sca-1) CD152 (CTLA-4) CD116 (GM-CSF Receptor) CD15s (Sialyl Lewis X) Neurofilament NF-M Restricted Trop-2 STRO-1 CD157 Committed Lymphoid CD24 Intracellular p150 Glued Oligodendrocyte - Type - 2 Progenitor Positive Markers Intracellular CD166 (ALCAM) Projenitor CD29 Smooth Muscle CDX2 Pax-5 Nucleostemin CD184 (CXCR4) Surface CD49f (Integrin 6) Astrocyte (0-2a) Progenitor Germ Cells α PSD-95 TAZ CD192 (CCR2) CD10 CD54 (ICAM-1) Surface SMN Vimentin CD201 (EPCR) CD34 CD81 CD15 (SSEA-1, Lewis x) Synapsin I Adipocyte Negative Markers Surface CD202b (TIE2) CD38 CD95 CD117 (SCF R, c-kit) Synaptophysin Type 1 Astrocyte (Fat) CD11a CD209 CD90 (Thy1) CD133 (AC133, Prominin-1) Fragilis Synaptotagmin CD11b CD209a CD117 (SCF R, c-kit) CD146 (MCAM, MUC18) Endothelium Myoblast Steel Syntaxin CD31 (PECAM-1) CD213a1 CD124 (IL-4 Receptor α) CD184 (CXCR4) Intracellular α-Synuclein Fibroblast CD34 CD213a2 CD127 (IL-7 Receptor α) CD271 Chondrocyte Blimp-1 α-Synuclein (pY125) Osteoblast CD45 CD249 HLA-DR CDw338 (ABCG2) (Cartilage) DAZL Tau Hemangioblast Adipocyte CD252 (OX-40 Ligand) TdT (Terminal Transferase) CD349 (Frizzled-9) (Bone) FABP9 Tubby Surface CD253 Notch1 Oligodendrocyte Endoderm Nanos β III Tubulin (TUJ1) Adipoq Promonin 2 CD262 Definitive Oct3/4 Tyrosine Hydroxylase Neuron Preadipocyte factor-1 PSA-NCAM CD309 (Flk1, KDR, Ly-73, VEGFR2) Endoderm Piwi/Hiwi Vimentin Secreted Intracellular CD322 Surface Stella (Dppa3) Ki67 Mesoderm Acrp30 (Adiponectin) CD325 (M-Cadherin) CD184 (CXCR4) VASA (DDX4) Musashi-1 & 2 Early mesoderm Leptin IP-10 Secreted Surface Myotube Intracellular Stem Cell Relevant Nestin Ly-6A/E (Sca-1) α Fetoprotein CD31 (PECAM-1) Signaling Noggin (Muscle) FABP4 Intracellular Intracellular Erk-MAPK Signaling Sox1 CD34 GLUT-4 HIF-1α N-Cadherin Secreted Sox2 CD325 (M-Cadherin) Chondrocyte (Cartilage) Nestin β-Catenin basic FGF Vimentin Ly6A/E (Sca-1) Type 2 Astrocyte Hematopoietic Plasmacytoid Surface STAT3 GATA4 Intracellular Intracellular Neural Crest Stem Cell CD44 STAT3 (pS727) HNF-1β (TCF-2) Brachyury C-Raf Surface Dendritic Cell CD151 STAT3 (pY705) HNF-3β (FoxA2) MIXL1 ERK CD49d (Integrin α4) Stem Cell Secreted STAT3-interacting protein 1 SOX-17 NF-YA ERK1 CD57 (HNK-1) Aggrecan Vimentin Liver - Hepatic Endoderm ERK1/2 (pT202/pY204) CD271 (p75, NGFR/NTR) Snail Collagen II Surface Secreted Monoblast Megakaryoblast Hematopoietic Stem ERK2 Notch1 Proerythroblast Myeloblast Committed Lymphoid Matrillin-4 Cells CD29 (Integrin β1) Intracellular BMP2 Intracellular CD44H (Pgp-1, H-CAM) ERK3 Positive Markers Surface MASH1 BMP4 Projenitor Osteonectin CD49f (Integrin α6) Mek1 CD31 (PECAM-1) Mek1 (pS298) Neurogenin 3 Cryptic SOX-9 CD90 (Thy-1) Nodal Erythroblast CD34 Mek1/2 (pS222) Glial-restricted progenitor Progranulocyte Myoblast (Muscle) Secreted Skeletal Muscle Monocyte CD44 Mek2 Surface Megakaryocyte Pre-NK Cell Surface Albumin Surface Pre B Cell CD59 p38 MAPK (pT180/pY182) A2B5 CD146 (MCAM, MUC18) ApoE FGF R1 CD146 (MCAM, MUC18) CD84 Ras N-Cadherin α Fetoprotein FGF R2 CD325 (MCAD) CD90.1 (Thy1.1) Jak-STAT Signaling Normoblast Intracellular Intracellular FGF R3 Intracellular CD90 (Thy1) Surface Thymocyte Acetylcholinesterase HNF-1α FGF R4 Actin CDw93 (C1qRp) gp130 Actin HNF-1β (TCF-2) Intracellular α-Actinin CD105 (Endoglin) gp130 (pS782) Basophilic μ-Calpain Tat-SF1 Nestin μ-Calpain Neutrophilic Eosinophilic B-Lymphoblast CD106 (VCAM-1) Intracellular NK Lymphoblast Desmin Intestine Type 1 astrocyte Desmin Myelocyte CD117 (SCF R, c-KIT) STAT1 Myelocyte Myelocyte β-Enolase Primitive Gut Tube Markers Surface β-Enolase CD133 (AC133, Prominin-1) STAT1 (pY701) Lactate Dehydrogenase (LDH) Intracellular A2B5 Myf5 CD164 (ALCAM) STAT3 Myf-5 HNF-1β (TCF-2) FGF R3 MyoD CD184 (CXCR4) STAT3 (pS727) T-Lymphoblast MyoD Intestinal Endoderm Markers Ran-2 Myogenin CD201 (EPCR) STAT3 (pY705) Myeloid Dendritic Basophilic Pax3 Intracellular Intracellular Myosin heavy chain Reticulocyte CD202b (TIE2) STAT4 Neutrophilic Eosinophilic Band Cell B Cell Pax7 Cdx2 GFAP Myosin light chain Cell CD309 (Flk1, KDR, Ly-73, VEGFR2) STAT4 (pY693) Band Cell PK-M Pancreas S-100B N-Cadherin Band Cell CDw338 (ABCG2, Bcrp1) STAT5 (MGF) Titin Surface Oligodendrocyte-type-2 astro- Titin NK Cell G-CSF CD49f (Integrin α6) STAT5 (MGF) (PY694) cyte (O-2A) precursor Osteoblast (Bone) Tropponin Ly-6A/E (Sca1) Neuropilin-2 STAT6 Surface Surface Smooth Muscle MRP1 Secreted STAT6 (pY641) A2B5 Alkaline Phosphatase Intracellular Notch1 Glucogon Notch Signaling CD140a (PDGF Receptor α chain) T Cell Fibronectin Surface Calmodulin p-Glycoprotein Insulin Intracellular IGFBP-3 Desmin Plasma Cell TIE2 (pY1102) Pancreatic polypeptide
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