DHX38 Antibody Cat. No.: 19-349

DHX38 Antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using DHX38 antibody (19-349) at dilution of 1:150 (40x lens).

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids IMMUNOGEN: 1133-1227 of human DHX38 (NP_054722.2).

TESTED APPLICATIONS: IHC, WB

WB: ,1:1000 - 1:2000 APPLICATIONS: IHC: ,1:50 - 1:200

POSITIVE CONTROL: 1) HeLa

2) SKOV3

September 27, 2021 1 https://www.prosci-inc.com/dhx38-antibody-19-349.html 3) U-87MG

4) MCF7

5) DU145

6) Mouse testis

PREDICTED MOLECULAR Observed: 140kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: DHX38

DDX38, PRP16, PRPF16, RP84, pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16, ATP-dependent RNA helicase DHX38, DEAD/H (Asp-Glu-Ala-Asp/His) box ALTERNATE NAMES: polypeptide 38, DEAH (Asp-Glu-Ala-His) box polypeptide 38, DEAH box protein 38, PRP16 homolog of S.cerevisiae

GENE ID: 9785

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their BACKGROUND: distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process.

September 27, 2021 2 https://www.prosci-inc.com/dhx38-antibody-19-349.html ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 3 https://www.prosci-inc.com/dhx38-antibody-19-349.html