Reportable Diseases in Michigan – by Pathogen
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Official Nh Dhhs Health Alert
THIS IS AN OFFICIAL NH DHHS HEALTH ALERT Distributed by the NH Health Alert Network [email protected] May 18, 2018, 1300 EDT (1:00 PM EDT) NH-HAN 20180518 Tickborne Diseases in New Hampshire Key Points and Recommendations: 1. Blacklegged ticks transmit at least five different infections in New Hampshire (NH): Lyme disease, Anaplasma, Babesia, Powassan virus, and Borrelia miyamotoi. 2. NH has one of the highest rates of Lyme disease in the nation, and 50-60% of blacklegged ticks sampled from across NH have been found to be infected with Borrelia burgdorferi, the bacterium that causes Lyme disease. 3. NH has experienced a significant increase in human cases of anaplasmosis, with cases more than doubling from 2016 to 2017. The reason for the increase is unknown at this time. 4. The number of new cases of babesiosis also increased in 2017; because Babesia can be transmitted through blood transfusions in addition to tick bites, providers should ask patients with suspected babesiosis whether they have donated blood or received a blood transfusion. 5. Powassan is a newer tickborne disease which has been identified in three NH residents during past seasons in 2013, 2016 and 2017. While uncommon, Powassan can cause a debilitating neurological illness, so providers should maintain an index of suspicion for patients presenting with an unexplained meningoencephalitis. 6. Borrelia miyamotoi infection usually presents with a nonspecific febrile illness similar to other tickborne diseases like anaplasmosis, and has recently been identified in one NH resident. Tests for Lyme disease do not reliably detect Borrelia miyamotoi, so providers should consider specific testing for Borrelia miyamotoi (see Attachment 1) and other pathogens if testing for Lyme disease is negative but a tickborne disease is still suspected. -
Case Definition for Non-Pestis Yersiniosis Check This Box If This Po
19-ID-03 Committee: Infectious Disease Title: Case Definition for Non-pestis Yersiniosis ☒Check this box if this position statement is an update to an existing standardized surveillance case definition: 18-ID-02 Synopsis: This position statement updates the case definition for non-pestis yersiniosis through the clarification of laboratory criteria. I. Statement of the Problem Non-pestis yersiniosis is an infection caused most commonly by the bacteria Yersinia enterocolitica or Yersinia pseudotuberculosis. These bacteria are normal intestinal and oropharyngeal colonizers of swine, and most commonly cause infections in children under 10 years of age, or adults over 70 years of age, through contaminated food. After Salmonella, Shigella, Campylobacter, and Shiga-toxin producing E. coli, th it is the 5 most commonly reported gastrointestinal bacterial illness reported through CDC Foodborne Diseases Active Surveillance Network (FoodNet), which monitors 10 sites in the United States for nine enteric pathogens transmitted through food. The increasing use of culture-independent diagnostic tests (CIDTs) in all parts of clinical medicine, and particularly for gastrointestinal illnesses, has also increased recognition of certain pathogens. Data from 2016 from FoodNet show a 29% increase in culture-confirmed and a 91% increase in CIDT-diagnosed Yersinia infections when compared to the 2013-2015 time frame. Yersinia enterocolitica and/or Yersinia pseudotuberculosis infections are reportable in 38 states, but no standard national definition exists for confirmed and probable cases. This position statement proposes a standardized case definition for non-pestis yersiniosis. II. Background and Justification Yersinia enterocolitica and Yersinia pseudotuberculosis are Gram negative rod-shaped or coccoid organisms that can be isolated from many animals and are most often transmitted to humans from undercooked or contaminated pork. -
Genetic Engineering and Sustainable Crop Disease Management: Opportunities for Case-By-Case Decision-Making
sustainability Review Genetic Engineering and Sustainable Crop Disease Management: Opportunities for Case-by-Case Decision-Making Paul Vincelli Department of Plant Pathology, 207 Plant Science Building, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA; [email protected] Academic Editor: Sean Clark Received: 22 March 2016; Accepted: 13 May 2016; Published: 20 May 2016 Abstract: Genetic engineering (GE) offers an expanding array of strategies for enhancing disease resistance of crop plants in sustainable ways, including the potential for reduced pesticide usage. Certain GE applications involve transgenesis, in some cases creating a metabolic pathway novel to the GE crop. In other cases, only cisgenessis is employed. In yet other cases, engineered genetic changes can be so minimal as to be indistinguishable from natural mutations. Thus, GE crops vary substantially and should be evaluated for risks, benefits, and social considerations on a case-by-case basis. Deployment of GE traits should be with an eye towards long-term sustainability; several options are discussed. Selected risks and concerns of GE are also considered, along with genome editing, a technology that greatly expands the capacity of molecular biologists to make more precise and targeted genetic edits. While GE is merely a suite of tools to supplement other breeding techniques, if wisely used, certain GE tools and applications can contribute to sustainability goals. Keywords: biotechnology; GMO (genetically modified organism) 1. Introduction and Background Disease management practices can contribute to sustainability by protecting crop yields, maintaining and improving profitability for crop producers, reducing losses along the distribution chain, and reducing the negative environmental impacts of diseases and their management. -
Preventing Foodborne Illness: Yersiniosis1 Aswathy Sreedharan, Correy Jones, and Keith Schneider2
FSHN12-09 Preventing Foodborne Illness: Yersiniosis1 Aswathy Sreedharan, Correy Jones, and Keith Schneider2 What is yersiniosis? Yersiniosis is an infectious disease caused by the con- sumption of contaminated food contaminated with the bacterium Yersinia. Most foodborne infections in the US resulting from ingestion of Yersinia species are caused by Y. enterocolitica. Yersiniosis is characterized by common symptoms of gastroenteritis such as abdominal pain and mild fever (8). Most outbreaks are associated with improper food processing techniques, including poor sanitation and improper sterilization techniques by food handlers. The dis- ease is also spread by the fecal–oral route, i.e., an infected person contaminating surfaces and transmitting the disease to others by not washing his or her hands thoroughly after Figure 1. Yersinia enterocolitica bacteria growing on a Xylose Lysine going to the bathroom. The bacterium is prevalent in the Sodium Deoxycholate (XLD) agar plate. environment, enabling it to contaminate our water and Credits: CDC Public Health Image Library (ID# 6705). food systems. Outbreaks of yersiniosis have been associated with unpasteurized milk, oysters, and more commonly with What is Y. enterocolitica? consumption of undercooked dishes containing pork (8). Yersinia enterocolitica is a small, rod-shaped, Gram- Yersiniosis incidents have been documented more often negative, psychrotrophic (grows well at low temperatures) in Europe and Japan than in the United States where it is bacterium. There are approximately 60 serogroups of Y. considered relatively rare. According to the Centers for enterocolitica, of which only 11 are infectious to humans. Disease Control and Prevention (CDC), approximately Of the most common serogroups—O:3, O:8, O:9, and one confirmed Y. -
Zoonotic Diseases Fact Sheet
ZOONOTIC DISEASES FACT SHEET s e ion ecie s n t n p is ms n e e s tio s g s m to a a o u t Rang s p t tme to e th n s n m c a s a ra y a re ho Di P Ge Ho T S Incub F T P Brucella (B. Infected animals Skin or mucous membrane High and protracted (extended) fever. 1-15 weeks Most commonly Antibiotic melitensis, B. (swine, cattle, goats, contact with infected Infection affects bone, heart, reported U.S. combination: abortus, B. suis, B. sheep, dogs) animals, their blood, tissue, gallbladder, kidney, spleen, and laboratory-associated streptomycina, Brucellosis* Bacteria canis ) and other body fluids causes highly disseminated lesions bacterial infection in tetracycline, and and abscess man sulfonamides Salmonella (S. Domestic (dogs, cats, Direct contact as well as Mild gastroenteritiis (diarrhea) to high 6 hours to 3 Fatality rate of 5-10% Antibiotic cholera-suis, S. monkeys, rodents, indirect consumption fever, severe headache, and spleen days combination: enteriditis, S. labor-atory rodents, (eggs, food vehicles using enlargement. May lead to focal chloramphenicol, typhymurium, S. rep-tiles [especially eggs, etc.). Human to infection in any organ or tissue of the neomycin, ampicillin Salmonellosis Bacteria typhi) turtles], chickens and human transmission also body) fish) and herd animals possible (cattle, chickens, pigs) All Shigella species Captive non-human Oral-fecal route Ranges from asymptomatic carrier to Varies by Highly infective. Low Intravenous fluids primates severe bacillary dysentery with high species. 16 number of organisms and electrolytes, fevers, weakness, severe abdominal hours to 7 capable of causing Antibiotics: ampicillin, cramps, prostration, edema of the days. -
Chapter 2 Disease and Disease Transmission
DISEASE AND DISEASE TRANSMISSION Chapter 2 Disease and disease transmission An enormous variety of organisms exist, including some which can survive and even develop in the body of people or animals. If the organism can cause infection, it is an infectious agent. In this manual infectious agents which cause infection and illness are called pathogens. Diseases caused by pathogens, or the toxins they produce, are communicable or infectious diseases (45). In this manual these will be called disease and infection. This chapter presents the transmission cycle of disease with its different elements, and categorises the different infections related to WES. 2.1 Introduction to the transmission cycle of disease To be able to persist or live on, pathogens must be able to leave an infected host, survive transmission in the environment, enter a susceptible person or animal, and develop and/or multiply in the newly infected host. The transmission of pathogens from current to future host follows a repeating cycle. This cycle can be simple, with a direct transmission from current to future host, or complex, where transmission occurs through (multiple) intermediate hosts or vectors. This cycle is called the transmission cycle of disease, or transmission cycle. The transmission cycle has different elements: The pathogen: the organism causing the infection The host: the infected person or animal ‘carrying’ the pathogen The exit: the method the pathogen uses to leave the body of the host Transmission: how the pathogen is transferred from host to susceptible person or animal, which can include developmental stages in the environment, in intermediate hosts, or in vectors 7 CONTROLLING AND PREVENTING DISEASE The environment: the environment in which transmission of the pathogen takes place. -
Family Outbreak of Yersiniosis TOM MARTIN,L* GORDON F
JOURNAL OF CLINICAL MICROBIOLOGY, OCt. 1982, p. 622-626 Vol. 16, No. 4 0095-1 137/82/100622-05$02.00/0 Copyright © 1982, American Society for Microbiology Family Outbreak of Yersiniosis TOM MARTIN,l* GORDON F. KASIAN,2 AND STANLEY STEAD3 Departments of Microbiology,t Pediatrics,2 and Social and Preventive Medicine,3 University of Saskatchewan, Saskatoon, Saskatchewan, Canada 57N OWO Received 1 February 1982/Accepted 24 June 1982 Yersinia enterocolitica biotype 1, serotype 0:21 was isolated from feces or rectal washings of three members of one family in northwestern Saskatchewan. The three isolates gave positive pathogenicity tests in guinea pigs with cultures grown at 22°C as inoculum. All three cases showed clinical symptoms consistent with yersiniosis. All three cases had symptoms of diarrhea and abdominal pain, and two cases had recorded fever. In two cases, appendicitis was initially suspect. One case with ileitis and peritonitis was fatal. The environmental source of the infection was not found, but river water, milk, and person-to-person spread are discussed as possible sources of the infections. The need for microbiology laboratories to culture stool specimens specifically for Y. enterocolitica, using cold-enrichment techniques is emphasized. This family outbreak of yersiniosis provides further evidence that certain biotype 1 strains of Y. enterocolitica are pathogenic. Yersinia enterocolitica is a gram-negative ba- ferred by air ambulance to University Hospital, Saska- cillus now classified as a member of the family toon. Enterobacteriaceae. A particular characteristic Two stool specimens obtained on the second and this is its to survive and sixth days after his admission to University Hospital of organism ability were negative for ova and parasites and negative for multiply at low temperatures. -
Z:\My Documents\WPDOCS\IACUC
ZOONOTIC DISEASES OF LABORATORY, AGRICULTURAL, AND WILDLIFE ANIMALS July, 2007 Michael S. Rand, DVM, DACLAM University Animal Care University of Arizona PO Box 245092 Tucson, AZ 85724-5092 (520) 626-6705 E-mail: [email protected] http://www.ahsc.arizona.edu/uac Table of Contents Introduction ............................................................................................................................................. 3 Amebiasis ............................................................................................................................................... 5 B Virus .................................................................................................................................................... 6 Balantidiasis ........................................................................................................................................ 6 Brucellosis ........................................................................................................................................ 6 Campylobacteriosis ................................................................................................................................ 7 Capnocytophagosis ............................................................................................................................ 8 Cat Scratch Disease ............................................................................................................................... 9 Chlamydiosis ..................................................................................................................................... -
61% of All Human Pathogens Are Zoonotic (Passed from Animals to Humans), and Many Are Transmitted Through Inhaling Dust Particles Or Contact with Animal Wastes
Zoonotic Diseases Fast Facts: 61% of all human pathogens are zoonotic (passed from animals to humans), and many are transmitted through inhaling dust particles or contact with animal wastes. Some of the diseases we can get from our pets may be fatal if they go undetected or undiagnosed. All are serious threats to human health, but can usually be avoided by observing a few precautions, the most effective of which is washing your hands after touching animals or their wastes. Regular visits to the veterinarian for prevention, diagnosis, and treatment of zoonotic diseases will help limit disease in your pet. Source: http://www.cdc.gov/healthypets/ Some common zoonotic diseases humans can get through their pets: Zoonotic Disease & its Effect on How Contact is Made Humans Bartonellosis (cat scratch disease) – an Bartonella bacteria are transferred to humans through infection from the bacteria Bartonella a bite or scratch. Do not play with stray cats, and henselae that causes fever and swollen keep your cat free of fleas. Always wash hands after lymph nodes. handling your cat. Capnocytophaga infection – an Capnocytophaga canimorsus is the main human infection caused by bacteria that can pathogen associated with being licked or bitten by an develop into septicemia, meningitis, infected dog and may present a problem for those and endocarditis. who are immunosuppressed. Cellulitis – a disease occurring when Bacterial organisms from the Pasteurella species live bacteria such as Pasteurella multocida in the mouths of most cats, as well as a significant cause a potentially serious infection of number of dogs and other animals. These bacteria the skin. -
Ask a Scientist: How Do People Become Infected with Germs?
One way to think about how living things get sick is to imagine a triangle. The three corners represent the environment... ...the host... All three aspects of this triangle must come ...and the cause of the disease, together for disease to occur. Disease the Agent. agents can be non-infectious or infectious. Non-infectious agents are non-living things that are toxic to the host, like radiation or chemicals... ...while infectious agents are organisms that invade a host to survive. Only infectious agents can spread, or transmit, between hosts. Infectious disease agents, otherwise known as pathogens, A person can become infected with a must infect a host pathogen when in the same environment in order to grow, or as the agent... replicate. Human pathogens, like viruses, bacteria, and parasites, evolved to infect people. Their survival is dependent on quickly invading, making more of themselves, and efficiently transmitting to others. If a pathogen gets past a host’s defenses, it will attempt to infect the host and begin replicating itself. ...and don’t have enough protection in the form The subsequent battle between Many cells will be destroyed as of physical barriers or the germs and the body’s germs kill them through replicating pre-existing immunity. immune system will cause the and as collateral damage from the symptoms of illness. activated immune cells. That’s just how one person gets infected, but how does disease spread? Well, if sick people go around sneezing and coughing without covering their mouth or frequently washing their hands... ...they are actually spreading pathogens all over the environment around them. -
Tularemia (CFSPH)
Tularemia Importance Tularemia is a zoonotic bacterial disease with a wide host range. Infections are most prevalent among wild mammals and marsupials, with periodic epizootics in Rabbit Fever, lagomorphs and rodents, but clinical cases also occur in sheep, cats and other Deerfly Fever, domesticated species. A variety of syndromes can be seen, but fatal septicemia is Meat-Cutter’s Disease common in some species. In humans, tularemia varies from a localized infection to Ohara Disease, fulminant, life-threatening pneumonia or septicemia. Francis Disease Tularemia is mainly seen in the Northern Hemisphere, where it has recently emerged or re-emerged in some areas, including parts of Europe and the Middle East. A few endemic clinical cases have also been recognized in regions where this disease Last Updated: June 2017 was not thought to exist, such as Australia, South Korea and southern Sudan. In some cases, emergence may be due to increased awareness, surveillance and/or reporting requirements; in others, it has been associated with population explosions of animal reservoir hosts, or with social upheavals such as wars, where sanitation is difficult and infected rodents may contaminate food and water supplies. Occasionally, this disease may even be imported into a country in animals. In 2002, tularemia entered the Czech Republic in a shipment of sick pet prairie dogs from the U.S. Etiology Tularemia is caused by Francisella tularensis (formerly known as Pasteurella tularensis), a Gram negative coccobacillus in the family Francisellaceae and class γ- Proteobacteria. Depending on the author, either three or four subspecies are currently recognized. F. tularensis subsp. tularensis (also known as type A) and F. -
Neglected Tropical Diseases in The
Qian et al. Infectious Diseases of Poverty (2019) 8:86 https://doi.org/10.1186/s40249-019-0599-4 SCOPING REVIEW Open Access Neglected tropical diseases in the People’s Republic of China: progress towards elimination Men-Bao Qian1, Jin Chen1, Robert Bergquist2, Zhong-Jie Li3, Shi-Zhu Li1, Ning Xiao1, Jürg Utzinger4,5 and Xiao-Nong Zhou1* Abstract Since the founding of the People’s Republic of China in 1949, considerable progress has been made in the control and elimination of the country’s initial set of 11 neglected tropical diseases. Indeed, elimination as a public health problem has been declared for lymphatic filariasis in 2007 and for trachoma in 2015. The remaining numbers of people affected by soil-transmitted helminth infection, clonorchiasis, taeniasis, and echinococcosis in 2015 were 29.1 million, 6.0 million, 366 200, and 166 100, respectively. In 2017, after more than 60 years of uninterrupted, multifaceted schistosomiasis control, has seen the number of cases dwindling from more than 10 million to 37 600. Meanwhile, about 6000 dengue cases are reported, while the incidence of leishmaniasis, leprosy, and rabies are down at 600 or fewer per year. Sustained social and economic development, going hand-in-hand with improvement of water, sanitation, and hygiene provide the foundation for continued progress, while rigorous surveillance and specific public health responses will consolidate achievements and shape the elimination agenda. Targets for poverty elimination and strategic plans and intervention packages post-2020 are important opportunities for further control and elimination, when remaining challenges call for sustainable efforts. Keywords: Control, Elimination, People's Republic of China, Neglected tropical diseases Multilingual abstracts deprived urban settings [1, 2].