Article Balance between Protection and Pathogenic Response to Aerosol Challenge with Mycobacterium tuberculosis (Mtb) in Mice Vaccinated with TriFu64, a Fusion Consisting of Three Mtb Antigens Sadaf Sulman 1,2, Benjamin O. Savidge 1,3 , Kawther Alqaseer 1,3,4, Mrinal K. Das 1,3, Neda Nezam Abadi 1,5, John E. Pearl 1,3, Obolbek Turapov 1,3, Galina V. Mukamolova 1,3, M. Waheed Akhtar 2 and Andrea May Cooper 1,3,* 1 Department Respiratory Sciences, University of Leicester, Leicester LE1 7RH, UK;
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[email protected] 3 Leicester Tuberculosis Research Group—LTBRG, University of Leicester, Leicester LE1 7RH, UK 4 Department of Basic Science, Faculty of Nursing, University of Kufa, P.O. Box 21, Kufa, Najaf Governorate, Citation: Sulman, S.; Savidge, B.O.; Najaf 540011, Iraq 5 APC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland Alqaseer, K.; Das, M.K.; Nezam * Correspondence:
[email protected]; Tel.: +44-(0)116-252-2957; Fax: +44-(0)116-252-5030 Abadi, N.; Pearl, J.E.; Turapov, O.; Mukamolova, G.V.; Akhtar, M.W.; Cooper, A.M. Balance between Abstract: Tuberculosis vaccines capable of reducing disease worldwide have proven difficult to Protection and Pathogenic Response develop.