SHREE RENUKA INSTITUTE PHARMA HUB

308, Business Square, above Vijay Sales,

Krishnabaug Char Rasta, Maninagar

“Don’t judge each day by the harvest you reap, but the seeds you plant.”

Pharmacology drugs classification

Sachin Phatak Harshit Jadav (+91)-9998957197 (+91)-7383887193

CLASSIFICATION OF ANTI TUBERCULOSIS DRUGS

First line . Ethambutol (EMB) . Iisoniazid ( INH) . Pyrazinamide ( PZA) . Rifampicin (RMP) . Steptomycin Second line . P-aminosalicylic acid (PAS) . Cycloserine . Aminoglycosides: e.g., amikacin & kanamycin . Polypeptides: e.g., capreomycin . Fluoroquinolones: e.g., ciprofloxacin , levofloxacin . Thioamides: e.g. Ethionamide, prothionamide Third line . rifabutin . macrolides: e.g., clarithromycin . thioacetazone . thioridazine

CLASSIFICATION OF ANTI LEPROTIC DRUG

 Sulfone derivaties:  Phenazine dye : Clofazimine  Antituberculardrugs: Rifampin, Ethionamide, Prothionamide

CLASSIFICATION OF ANTIVIRUS DRUGS

 A) Agents to Treat Herpes Simplex Virus: Acyclovir, Valacyclovir, Famciclovir, Penciclovir, Ganciclovir, Idoxuridine, Foscarnet  B) Agents to Treat Retrovirus (i) NRTl (Nucleoside reverse trenscriptase inhibitor): Zidovudine , Stavudine, Lamivudine, Abacavir, Didanosine, Zalcitabine, (ii) NNRTI (Non-Nucleoside reverse trenscriptase inhibitor) Nevirapine, Efavirenz, Delavirdine  (iii) PI (Proteasein hibitor): Saquinavir, Ritotonavir, Indinavir, Nelfinavir  Nucleotide RTI: tenofovir  Integrase inhibitor: raltegravir  Fusion inhibitor: enfuvirtide  CCR5 inhibitor: meraviroc  C) Agents to Treat lnfluenza virus : Amantadine, Rimantadine  D) Nonselective antiviral drugs : Adefovir, Ribavirin, Lamivudine

CLASSIFICATION OF ANTI FUNGAL AGENT

A. Polyenes Macrolide :AmphotericinB , ,Hamycin, Heterocyclic benzofuran: B. : ,, , : ,, C. Squalene epoxidase inhibitors : e.g. & . Other :, , Benzoic acid,Sod. Thiosulfate etc

ANTIAMOEBIC DRUGS

Drug Mode of Action Arsenics & Antimonials Binds with SH groups; selectively inhibits pyruvate kinase or phosphofructokinase so affects cellular structure, function, synthesis or energy production Paromomycin Interferes with initiation complex; causes misreading of mRNA so affects structure, function, synthesis of protein Diamidines () Binds to kinetoplast DNA Affects synthesis or structure of nucleic acids Metronidazole Inhibits DNA replication so affects synthesis or structure of nucleic acids Nifurtimox Generation of toxic oxygen radicals Suramin Binds to plasma proteins; inhibits glucose utilization Iodoquinol Steadily liberates inorganic iodine Eflornithine Inhibits ornithine decarboxylase and affects cell division, differentiation

CLASSIFICATION OF ANTIMALARIAL DRUGS:

Sr. No. Class Drugs

1 4-Aminoquinoline Chloroquine, Amodiaquine

2. Quinoline methanol Quinine, Quinidine , Mefloquine

3. 8-Aminoquinoline Primaquine

4. Proguanil derivatives Proguanil, Chlorproguanil

5 Phenanthrene methanol Halofantrine

6 Amyl alcohol Lumefantrine