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Forschungsbericht 1999 – 2001 FAU Med

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Forschungsbericht 1999 – 2001 FAU Med Forschungsbericht Research Report Medizinische Fakultät 1999 – 2001 Vorwort 2 Vorwort des Dekans der Medizinischen Fakultät Mit dem Forschungsbericht zu den Jahren 1999-2001 legt die Medizinische Fakultät der Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg zum zweiten Mal einen Überblick über die Forschungsschwerpunkte und Forschungsprojekte der einzelnen klinischen und theoretischen Einrichtungen vor. Sie will Rechenschaft geben über die erarbeiteten wissenschaftli- chen Leistungen, die sich an internationalen Kriterien messen. Der Forschungsbericht richtet sich an die interessierte Öffent- lichkeit, damit an jedermann auch außerhalb der Universität, er dient aber auch der universitätsinternen und inter- und innerfakultativen Information. Er spiegelt die Forschungsaktivitäten aller wissenschaftlichen Einrichtungen aus den Jahren 1999-2001 wider, in dem er die in diesem Zeitraum bearbeiteten Forschungsprojekte, erschienenen Publikationen, abge- schlossene Habilitationen, Promotionen und Drittmittelgeber listet. Ich danke allen Mitgliedern der Medizinischen Fakultät, die an der Erstellung dieses Berichtes mitgewirkt haben. Ein beson- ders herzlicher Dank gilt der Forschungsreferentin Frau Dr. Schnetz für ihre äusserst umfangreiche logistische und redaktio- nelle Tätigkeit. Der hier vorgelegte Forschungsbericht ist auch über die Homepage des Dekanats der Medizinischen Fakultät abzurufen (http://www.Dekanat.med.uni-erlangen.de) Erlangen, im April 2002 Univ.-Prof. Dr. M. Röllinghoff Dekan Preface 3 Preface of the Dean of the Medical Faculty With the Research Report 1999-2001 the Medical Faculty of the University Erlangen-Nürnberg presents for the second time a synopsis of the scientific activities, that were carried out in the university hospital as well as in the medical research institutes. The Medical Faculty will give account of its scientific achievements, which are to be measured with international criteria. The Research Report addresses the interested public, i.e. everyone outside of the university, but it serves also for the intramural distribution of information. The Research Report mirrors the research activities of all scientific institutions of the years 1999-2001, by compiling all research projects, all published research report, all successful ‘habilitations’ and theses, as well as mentioning the funding organizations. I am indebted to all members of the Medical Faculty, who have help to put together this report. My special thanks go to the research assistant of the Medical Faculty, Frau Dr. Schnetz, for her extensive logistic and editorial activity. The Research Report can also be read via the homepage of the Dean’s office of the Medical Faculty (http://www.Dekanat.med.uni-erlangen.de) Erlangen, April 2002 Univ.-Prof. Dr. M. Röllinghoff Dean 4 Inhalt 2 Vorwort 12 Einleitung V ORKLINISCHE I NSTITUTE A Anatomisches Institut 28 Lehrstuhl für Anatomie I 34 Lehrstuhl für Anatomie II Institut für Physiologie und Experimentelle Pathophysiologie 41 Lehrstuhl für Physiologie Institut für Physiologie und Kardiologie 50 Lehrstuhl für Physiologie (Vegetative Physiologie) Institut für Biochemie 55 Lehrstuhl für Biochemie und Molekulare Medizin 64 Lehrstuhl für Biochemie und Pathobiochemie Institut für Medizininformatik, Biometrie und Epidemiologie 70 Lehrstuhl für Biometrie und Epidemiologie Institut für Geschichte und Ethik der Medizin 78 Lehrstuhl für Geschichte und Ethik der Medizin K LINISCH-THEORETISCHE I NSTITUTE B Pathologisch-Anatomisches Institut 83 Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie Institut für Klinische Mikrobiologie, Immunologie und Hygiene 90 Lehrstuhl für Hygiene und Medizinische Mikrobiologie Institut für Klinische und Molekulare Virologie 98 Lehrstuhl für Klinische Virologie Institut für Experimentelle und Klinische Pharmakologie und Toxikologie 108 Lehrstuhl für Pharmakologie und Toxikologie 115 Lehrstuhl für Klinische Pharmakologie und Toxikologie Institut für Humangenetik 124 Lehrstuhl für Humangenetik Institut für Rechtsmedizin 131 Lehrstuhl für Rechtsmedizin Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin 138 Lehrstuhl für Arbeits- und Sozialmedizin Institut für Medizinische Physik 145 Lehrstuhl für Medizinische Physik Institut für Experimentelle Medizin 151 Lehrstuhl für Experimentelle Medizin I (Bindegewebsforschung) 162 Lehrstuhl für Experimentelle Medizin II (Molekulare Tumorforschung) 5 Table of Contents 3 Preface 13 Introduction N ON-CLINICAL I NSTITUTIONS A Anatomical Institute 28 Chair of Anatomy I 34 Chair of Anatomy II Institute for Physiology and Experimental Pathophysiology 41 Chair of Physiology Institute for Physiology and Cardiology 50 Chair of Physiology (Vegetative Physiology) Institute for Biochemistry 55 Chair of Biochemistry and Molecular Medicine 64 Chair of Biochemistry and Pathobiochemistry Institute for Medical Informatics, Biometry, and Epidemiology 70 Chair of Biometry and Epidemiology Institute for the History and Ethics of Medicine 78 Chair of the History and Ethics of Medicine C LINICAL T HEORETICAL I NSTITUTIONS B Institute for Anatomical Pathology 83 Chair of General Pathology and Anatomical Pathology Institute for Clinical Microbiology, Immunology and Hygiene 90 Chair of Hygiene and Medical Microbiology Institute for Clinical and Molecular Virology 98 Chair of Clinical Virology Institute for Experimental and Clinical Pharmakology and Toxicology 108 Chair of Pharmacology and Toxicology 115 Chair of Clinical Pharmacology and Toxicology Institute for Human Genetics 124 Chair of Human Genetics Institute for Forensic Medicine 131 Chair of Forensic Medicine Institute and Policlinic for Occupational, Social, and Environmental Medicine 138 Chair of Occupational and Social Medicine Institute for Medical Physics 145 Chair of Medical Physics Institute for Experimental Medicine 151 Chair of Experimental Medicine I (Connective Tissue Research) 162 Chair of Experimental Medicine II (Molecular Tumor Research) 6 Inhalt K LINISCHE L EHRSTÜHLE AUSSERHALB DES C U NIVERITÄTSKLINIKUMS Institut für Biomedizin des Alterns 167 Lehrstuhl für Innere Medizin V (Gerontologie) Orthopädische Klinik mit Poliklinik 176 Lehrstuhl für Orthopädie mit Orthopädischer Chirurgie 185 Abteilung für Orthopädische Rheumatologie 191 Stiftungsprofessur für Orthopädische und Rheumatologische Rehabilitation U NIVERSITÄTSKLINIKUM D Medizinische Klinik I mit Poliklinik 195 Lehrstuhl für Innere Medizin I (Gastroenterologie, Stoffwechselkrankheiten, Pneumologie, Endokrinologie, Infektiologie und Hepatologie) Medizinische Klinik II mit Poliklinik 216 Lehrstuhl für Innere Medizin II (Kardiologie und Angiologie) Medizinische Klinik III mit Poliklinik 224 Lehrstuhl für Innere Medizin III (Immunologie, Rheumatologie, Hämatologie und Internistische Onkologie) 240 Abteilung für Molekulare Immunologie Medizinische Klinik IV mit Poliklinik 244 Lehrstuhl für Innere Medizin IV (Nephrologie und Hypertensiologie) Nuklearmedizinische Klinik mit Poliklinik 254 Lehrstuhl für Klinische Nuklearmedizin Institut für Diagnostische Radiologie 258 Lehrstuhl für Diagnostische Radiologie Chirurgische Klinik mit Poliklinik 265 Lehrstuhl für Chirurgie 288 Abteilung für Kinderchirurgie 292 Abteilung für Unfallchirurgie 299 Abteilung für Transfusionsmedizin und Hämostaseologie Klinik für Herzchirurgie 304 Lehrstuhl für Herzchirurgie Urologische Klinik mit Poliklinik 311 Lehrstuhl für Urologie Klinik für Anästhesiologie 319 Lehrstuhl für Anästhesiologie Klinik für Frauenheilkunde mit Poliklinik und Hebammenschule 327 Lehrstuhl für Geburtshilfe und Frauenheilkunde Klinik und Poliklinik für Strahlentherapie 339 Lehrstuhl für Strahlentherapie Klinik mit Poliklinik für Kinder und Jugendliche 345 Lehrstuhl für Kinderheilkunde Dermatologische Klinik mit Poliklinik 356 Lehrstuhl für Haut- und Geschlechtskrankheiten 7 Table of Contents C LINICAL C HAIRS ADDITIONALLY TO THE C U NIVERSITY H OSPITAL Institute for Biomedicine of Aging 167 Chair of Medicine V (Gerontology) Department of Orthopaedics 176 Chair of Orthopaedics and Orthopaedic Surgery 185 Division of Orthopaedic Rheumatology 191 Endowed Chair of Orthopaedic - and Rheumatologic Rehabilitation D U NIVERSITY H OSPITAL Department of Medicine I 195 Chair of Medicine I (Gastroenterology, Metabolic Diseases, Lung Diseases, Endocrinology, Infectiology, and Hepatology) Department of Medicine II 216 Chair of Medicine II (Cardiology and Angiology) Department of Medicine III 224 Chair of Medicine III (Immunology, Rheumatology, Haematology, and Oncology) 240 Division of Molecular Immunology Department of Medicine IV 244 Chair of Medicine IV (Nephrology and Hypertensiology) Department of Nuclear Medicine 254 Chair of Nuclear Medicine Institute for Diagnostic Radiology 258 Chair of Diagnostic Radiology Department of Surgery 265 Chair of Surgery 288 Division of Paediatric Surgery 292 Division of Accident Surgery 299 Division of Transfusion Medicine and Haemostaseology Department of Cardiac Surgery 304 Chair of Cardiac Surgery Department of Urology 311 Chair of Urological Medicine Department of Anaesthesiology 319 Chair of Aenaesthesiology Department of Obstetrics and Gynaecology, School of Midwifery 327 Chair of Obstetrics and Gynaecology Department of Radiation Therapy 339 Chair of Radiation Therapy Department of Paediatrics 345 Chair of Paediatrics Department of Dermatology 356 Chair of Skin and Venereal Diseases 8 Inhalt Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke 366 Lehrstuhl für Hals-, Nasen- und Ohrenheilkunde 373 Abteilung für Phoniatrie und
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