www.aging‐us.com AGING 2017, Vol. 9, No. 11 Research Paper Expression of a novel CNPY2 isoform in colorectal cancer and its association with oncologic prognosis Jianhong Peng1,*, Qingjian Ou1,2,*, Jian Guo3,*, Zhizhong Pan1,*, Rongxin Zhang 1, Xiaojun Wu 1, Yujie Zhao1, Yuxiang Deng1, Caixia Li4, Fulong Wang1, Liren Li1, Gong Chen1, Zhenhai Lu1, Peirong Ding1, Desen Wan 1, Yujing Fang 1,2 1Department of Colorectal Surgery, Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P. R. China 2Department of Experimental Research, Sun Yat‐sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine,Guangzhou, Guangdong 510060, P. R. China 3Senboll Biotechnology Co., Ltd., Pingshan Bio‐pharmacy Business Accelerator Unit 205, Shenzhen, Guangdong 518000, P. R. China 4School of Mathematics and Computational Science, Sun Yat‐sen University, Guangzhou, Guangdong P. R. China *Equal contribution Correspondence to: Yujing Fang, Desen Wan; email:
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[email protected] Keywords: CNPY2 isoform2, colorectal cancer, expression, prognosis Received: September 24, 2017 Accepted: November 3, 2017 Published: November 13, 2017 Copyright: Peng et al. This is an open‐access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ABSTRACT Colorectal cancer (CRC) is a leading cause of cancer‐related mortality. Recently, we identified a novel biomarker, canopy fibroblast growth factor signaling regulator 2 (CNPY2) isoform2, and subsequently investigated its expression and prognostic value in CRC patients.