DISCLOSURE SUMMARY

As a sponsor accredited by the Accreditation Council for Continuing Medical Education, the International Association for the Study of Lung Cancer (IASLC) must insure balance, independence, objectivity, and scientific rigor in all its sponsored educational activities. All speakers/contributors participating in a sponsored activity are expected to disclose to the accredited provider any significant financial interest or other relationship(s) involving themselves or their spouse/partner within the last 12 months with any proprietary entity producing health care goods or services related to the content of the activity. The intent of this disclosure is not to prevent a speaker with a significant financial or other relationship from making the presentation, but rather to identify and resolve any conflicts of interest that may control the content of the activity. It is also intended that any potential conflict be identified openly so that the listeners have a full disclosure of the facts and may form their own judgments about the presentation. It remains for the audience to determine whether the speaker’s interests or relationships may influence the presentation with regard to exposition or conclusion. All other faculty/contributors have reported no commercial affiliation associated with this conference or intent to reference off-label/unapproved uses of products or devices in their presentations.

First Name Last Name Nature of Relevant Name of Company(s) Financial Relationship Nivedita Aanur Full-time/part-time Employee BMS Nivedita Aanur Stock Shareholder (directly BMS purchased) A Abbattista Full-time/part-time Employee A Abbattista Stock Shareholder (directly Pfizer purchased) Chihiro Abe Full-time/part-time Employee Daiichi Sankyo. Co., Ltd. Amy Abernethy Consultant Roche/, BMS, Helsinn Amy Abernethy Full-time/part-time Employee Flatiron Health (full time) Ellias Abreu Lima Honoraria Astrazeneca Nacer Abrouk Consultant EpicentRx, Inc Brenda Acevedo Grants/Research Support Acerta Pharma, Bristol-Myers Squibb, Nektar, Celldex, , Vascular Biogenics Brenda Acevedo Other (explain): Travel: Vascular Biogenics Joachim Aerts Consultant Amphera bv Joachim Aerts Consultant Lilly Joachim Aerts Grants/Research Support Amphera bv Joachim Aerts Other (explain): Amphera bv Daniel Afar Full-time/part-time Employee AbbVie Daniel Afar Stock Shareholder (directly AbbVie, may own stock purchased) Suresh Agarwal Full-time/part-time Employee Roche Charu Aggarwal Consultant Genentech, Roche Tanya Ahmad Grants/Research Support AstraZeneca, Boehringer Ingelheim, Eli- Lilly, Pfizer

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Tanya Ahmad Honoraria Boehringer Ingelheim, Neo Oncology Tanya Ahmad Other (explain): Boehringer Ingelheim, MSD, Pfizer, Pierre Fabre Myung-Ju Ahn Consultant AstraZeneca, BMS, Boehringer Ingelheim, MSD, Novartis Hiroaki Akamatsu Honoraria AstraZeneca, Eli Lilly, Chugai Pharmaceuticals, Boehringer Ingelheim, Merck, Pfizer, Ono Pharmaceuticals, Taiho Pharmaceuticals, Novartis Mikhail Akimov Full-time/part-time Employee Novartis Mikhail Akimov Stock Shareholder (directly Novartis purchased) Mahmood Alam Full-time/part-time Employee Pfizer Jordi Alcaraz Grants/Research Support Boheringer-Ingelheim Ekaterine Alexandris Full-time/part-time Employee Ekaterine Alexandris Stock Shareholder (directly Eli Lilly and Company purchased) Siraj Ali Full-time/part-time Employee Foundation Medicine Ash Alizadeh Consultant Roche Brian Allen Full-time/part-time Employee , Inc. Brian Allen Stock Shareholder (directly Myriad Genetics, Inc. purchased) Jared Allen Full-time/part-time Employee Oncimmune Ltd Justin Allen Full-time/part-time Employee Foundation Medicine Justin Allen Stock Shareholder (directly Foundation Medicine purchased) James Allison Consultant Bristol-Myers Squibb, , GlaxoSmithKline James Allison Honoraria Bristol-Myers Squibb James Allison Other (explain): Founder and advisor for Jounce Therapeutics James Allison Other (explain): Inventor of intellectual property owned by the University of California, Berkeley, and licensed to Bristol-Myers Squibb James Allison Other (explain): Member of the Parker Institute for Cancer Immunotherapy at M.D. Anderson Cancer Center Justyna Amelio Full-time/part-time Employee Amgen Justyna Amelio Stock Shareholder (directly Amgen purchased) Asim Amin Consultant BMS, Merck Asim Amin Grants/Research Support BMS, Merck, Prometheus, Akros Asim Amin Speakers Bureau BMS, Merck, Pfizer Kathy Amiri Full-time/part-time Employee Celgene (full-time) Kathy Amiri Stock Shareholder (directly Celgene purchased) Lukas Amler Full-time/part-time Employee Genentech Eunkyung An Full-time/part-time Employee Nantomics

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Helen Angell Full-time/part-time Employee AstraZeneca Eric Angevin Honoraria MSD Lakshmanan Annamalai Full-time/part-time Employee Merck Sharp & Dohme (MSD) Peter Ansell Full-time/part-time Employee AbbVie Peter Ansell Stock Shareholder (directly AbbVie, may own stock purchased) Scott Antonia Consultant BMS, Merck, AZ, BI Scott Antonia Honoraria BMS, Merck, AZ, BI Scott Antonia Other (explain): (travel, accomodations, expenses): BMS, Merck, AZ, BI Scott Antonia Stock Shareholder (directly Cellular Biomedicine Group purchased) Kouji Aoyama Full-time/part-time Employee Astellas Pharma Inc. Francisco Aparisi Grants/Research Support ROCHE Andrea Ardizzoni Grants/Research Support Celgene Andrea Ardizzoni Honoraria BMS, MSD Andrea Ardizzoni Other (explain): Boehringer Ingelheim, Eli-Lilly (Advisory board) Andrea Ardizzoni Speakers Bureau Pfizer, Novartis Osvaldo Arén Honoraria BMS Allison Armour Full-time/part-time Employee Endocyte Lyle Arnold Full-time/part-time Employee Biocept Ashwini Arunachalam Other (explain): Fellow at Merck & Co Ryoichi Asabe Full-time/part-time Employee Chugai Pharma Takashi Asakawa Full-time/part-time Employee Genentech, Inc. Paolo Ascierto Consultant BMS, Roche-Genentech, MSD, Ventana, Novartis, Amgen, Array Paolo Ascierto Grants/Research Support BMS, Roche-Genentech, Ventana Jalal Assouad Consultant , Shinji Atagi Grants/Research Support Chugai Pharmaceutical, Pfizer, Ono Pharmaceutical, Merck Serono, Boehringer Ingelheim, AstraZeneca, Taiho Pharmaceutical, Yakult , Eli Lilly Shinji Atagi Speakers Bureau AstraZeneca, Taiho Pharmaceutical Thomas Atkinson Grants/Research Support NIH P30 CA08748-49 Akin Atmaca Consultant BMS Akin Atmaca Honoraria BMS Clarisse Audigier Valette Consultant Amgen, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Lilly, Novartis, PFIZER, Roche, Sysmex Clarisse Audigier Valette Grants/Research Support Boehringer Ingelheim, Bristol-Myers Squibb, Novartis, Roche Clarisse Audigier Valette Honoraria BMS Sandra Aung Full-time/part-time Employee UbiVac

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Ricardo Avila Stock Shareholder (directly I am the founder and CEO of Accumetra, purchased) LLC. Accumetra develops phantoms and software to improve medical imaging decision making. Mark Awad Consultant Ariad, , Clovis, Nektar Paul Baas Consultant Bristol-Myers Squibb, Merck, Celgene, Verastem Paul Baas Grants/Research Support Bristol-Myers Squibb, Merck Jeffrey Bacha Other (explain): DelMar Pharmaceuticals, Inc. Barbara Baggiani Full-time/part-time Employee Menarini Silicon Biosystems Isaac Bai Full-time/part-time Employee Roche Christina Baik Other (explain): Advisory board: Member of Clovis Oncology advisory board to discuss treatment practices in non-small lung cancer, therapy efficacy, and safety profiles, Flince Research & Design Bogdana Balas Full-time/part-time Employee F. Hoffmann-La Roche Bogdana Balas Stock Shareholder (directly F. Hoffmann-La Roche purchased) Marcus Ballinger Full-time/part-time Employee Genentech Marcus Ballinger Stock Shareholder (directly Genentech, Roche purchased) Udai Banerji Grants/Research Support AstraZeneca Kimberly Banks Full-time/part-time Employee Guardant Health, Inc. Kimberly Banks Other (explain): Employee with stock ownership in Guardant Health, Inc. Kimberly Banks Stock Shareholder (directly Guardant Health, Inc. purchased) Jair Bar Consultant BMS, MSD, Roche, Astra Zeneca Joaquina Baranda Full-time/part-time Employee Halozyme Lisa Barbarotta Speakers Bureau Celgene, BMS, Novartis Fabrice Barlesi Consultant AstraZeneca, BMS Fabrice Barlesi Grants/Research Support BMS, Roche, Genetech Fabrice Barlesi Honoraria AstraZeneca, BMS, Eli Lilly and Company, Novartis Fabrice Barlesi Other (explain): Advisory board or board of directors: Roche Michael Barnes Full-time/part-time Employee Roche Carlos Barrios Consultant Boehringer-Ingelheim, GlaxoSmithKline, Novartis, Pfizer, Roche/Genentech, Eisai, Bioepis Carlos Barrios Grants/Research Support Pfizer, Novartis, Amgen, AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Taiho Pharmaceutical, , Merrimack, Merck, Abbvie, Astellas Pharma, Biomarin, Bristol-Myers Squibb, Daiichi Sankyo, Abraxis BioScience, AB Science, Asana Biosciences, Medivat Rich Barron Full-time/part-time Employee Amgen

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Rich Barron Stock Shareholder (directly Amgen purchased) Jose Barrueco Full-time/part-time Employee Boehringer Ingelheim Rachael Barton Honoraria Pfizer Mickael Basson Full-time/part-time Employee Eli Lilly and Company Volker Baum Full-time/part-time Employee Novartis Lyudmila Bazhenova Consultant AbbVie, AstraZeneca, BMS, Boehringer Ingelheim, Clovis Oncology, Genoptix, Heat Biologics, Pfizer, Roche/Genentech, Seattle Genetics, and Trovagene Lyudmila Bazhenova Grants/Research Support AbbVie, ARIAD, Astellas, Astex, AstraZeneca/MedImmune, Boehringer Ingelheim, Chugai, Clovis Oncology, Eisai, Eli Lilly, Heat Biologics, Johnson & Johnson, Merck, Mirati, NanoCarrier, Novartis, Pfizer, Roche/Genentech Lyudmila Bazhenova Honoraria Novartis Lyudmila Bazhenova Other (explain): Epic Sciences Lyudmila Bazhenova Speakers Bureau AstraZeneca, Novartis, Pfizer, Roche/Genentech Vanessa Beattie Honoraria Lilly Oncology, Pfizer, BMS Hubert Beaumont Full-time/part-time Employee MEDIAN Technologies D. Gwyn Bebb Consultant Astra Zeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly, Merck, Pfizer, Roche D. Gwyn Bebb Grants/Research Support Astra Zeneca, Boehringer Ingelheim Judith Bebchuk Full-time/part-time Employee Puma Inc. Anna Belilovski Other (explain): Teva Pharmaceutical Industries Ltd. (travel Rozenblum expenses) Timothy Bell Full-time/part-time Employee VisionGate Katherine Bellebaum Winfree Full-time/part-time Employee Eli Lilly and Company Aimee Bence Lin Full-time/part-time Employee Eli Lilly and Company Edmond Bendaly Consultant Novartis Edmond Bendaly Speakers Bureau Novartis , BMS, Eli Lilly & Co Sebastian Bender Full-time/part-time Employee Bayer AG Jennifer Benner Consultant Employee at Precision Health Economics which provides consulting services to Bristol-Myers Squibb Charles Bennett Consultant StraMar Tec, Inc. Kelly Bennett Full-time/part-time Employee Bristol-Myers Squibb Kelly Bennett Stock Shareholder (directly Bristol-Myers Squibb purchased) Jaafar Bennouna Consultant Boehringer Ingelheim; Novartis; Pierre Fabre Medicament; Roche Jaafar Bennouna Speakers Bureau Astra-Zeneca, Boehringer, Eli Lilly and Company, Roche Sabina Berezowska Consultant MSD Merck Sharp & Dohme AG, Roche Diagnostics (Schweiz) AG

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Sabina Berezowska Honoraria Roche Pharma (Schweiz) AG Sabina Berezowska Other (explain): MSD, Advisory Board Christine Berg Other (explain): Medial Early Sign, LLC Mark Berger Full-time/part-time Employee Kadmon Corporation Coen Bernaards Full-time/part-time Employee Genentech Sophie Bertrand Grants/Research Support Nektar, Celldex, Sanofi, Bristol-Myers Squibb, MedImmune, Acerta Pharma Sophie Bertrand Other (explain): Travel: Tocagen, ImmunoCellular Therapeutics David Berz Consultant Trovagene David Berz Speakers Bureau Astellas, Astra Zeneca, Boehringer Ingelheim, Genentech Peter Berzinec Consultant Boehringer Ingelheim, Eli Lilly, MSD, Pfizer Peter Berzinec Honoraria Boehringer Ingelheim Benjamin Besse Grants/Research Support Eli Lilly and Company, Genentech/Roche, OSE immunotherapeutics, Pfizer, Puma Biotechnology, Roche/Genentech Benjamin Besse Speakers or Advisory Board AstraZeneca, BMS, Boehringer-Ingelheim, Lilly, Pfizer, Roche-Genentech, Sanofi- Aventis, Clovis, GSK, Servier, EOS, Onxeo, OncoMed, Inivata, OSE Pharma Ingeborg Beunders Consultant Roche, Boehringer, Baxalta, Novartis, Celgene, Ratiopharm, Amgen, Merck Prabhu Bhagavatheeswaran Full-time/part-time Employee Bristol-Myers Squibb Prabhu Bhagavatheeswaran Other (explain): (travel, accomodations, expenses): Bristol- Myers Squibb Desai Bhardwaj Full-time/part-time Employee Astellas Anahita Bhathena Full-time/part-time Employee AbbVie Anahita Bhathena Stock Shareholder (directly AbbVie, may own stock purchased) Sheila Bheddah Full-time/part-time Employee AbbVie Stemcentrx Jaishree Bhosle Honoraria BMS, Pierre Faber Jaishree Bhosle Other (explain): (conference attendance - non-financial support): Otsuka Pharmaceuticals, (speaker fee/conference attendance support): Pierre Fabre, (speaker fee/conference attendance): BMS, advisory board and conference support (both personal fees and non-financial support): Boehringer Ingelheim John Bisi Full-time/part-time Employee G1 Therapeutics Fiona Blackhall Consultant AstraZeneca Fiona Blackhall Grants/Research Support AstraZeneca Fiona Blackhall Honoraria AstraZeneca Jenny Black-Shinn Full-time/part-time Employee McKesson Specialty Health Shannon Blais Full-time/part-time Employee Inivata Fernando Blanco Full-time/part-time Employee Trovagene

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Ana Blasco Grants/Research Support ROCHE Sara Blasco Cordellat Grants/Research Support ROCHE Jean-Yves Blay Consultant Roche, GSK, Novartis Jean-Yves Blay Grants/Research Support Roche, GSK, Novartis Jean-Yves Blay Honoraria Roche Cécile Blein Consultant Bristol-Myers Squibb George Blumenschein Consultant AbbVie George Blumenschein Consultant Bayer, BMS, Clovis, Merck George Blumenschein Grants/Research Support AstraZeneca, Bayer, BMS, Celgene, Merck, Novartis, Xcovery Holding Company Iryna Bocharova Other (explain): I am an employee of Analysis Group. Analysis Group has received funding from Novartis to partner on this study. Ceritinib is Novartis' product. Carolyn Bodnar Full-time/part-time Employee AstraZeneca Paolo Boffetta Consultant Edison SpA Paolo Boffetta Grants/Research Support National Institute Occupational Safety and Health, Centers for Disease Control Bjorn Bolinder Full-time/part-time Employee BMS Bjorn Bolinder Stock Shareholder (directly BMS purchased) Zeev Bomzon Full-time/part-time Employee Novocure Petri Bono Grants/Research Support Novartis Petri Bono Honoraria BMS, Pfizer, MSD, Orion Pharma Emma Booth Full-time/part-time Employee Amgen Emma Booth Stock Shareholder (directly Amgen purchased) Jeremy Booth Grants/Research Support Varian Medical Systems Walter Bordogna Full-time/part-time Employee F. Hoffmann-La Roche Walter Bordogna Stock Shareholder (directly F. Hoffmann-La Roche purchased) Hossein Borghaei Consultant BMS, Lilly, Genentech Roche, Pfizer, Boeringher-Ingelheim, Celgene, Trovegene Hossein Borghaei Consultant Janssen (Uncompensated) Hossein Borghaei Consultant Lilly, Bristol-Myers Squibb, Clovis, Genentech, Pfizer Hossein Borghaei Grants/Research Support Millenium (institution) Hossein Borghaei Honoraria BMS, Celgene Hossein Borghaei Other (explain): (Travel, Accomodations, Expenses): BMS, Lilly, Genentech, Clovis Diana Borthwick Honoraria Advisory board for Novartis / Boeringher Ingleheim / Astra Zeneca / MSD Karin Bowen Full-time/part-time Employee AstraZeneca Marley Boyd Full-time/part-time Employee McKesson Specialty Health Mark Boye Full-time/part-time Employee Eli Lilly and Compnay

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Michael Boyer Grants/Research Support Astra Zeneca, Boehringer Ingelheim, Clovis, Roche, Genetech, Pfizer, Eli Lilly, Bristol Myers Squibb, Merck Sharpe and Dohme Michael Boyer Other (explain): Astra Zeneca (Advisory board) Carrie Brachmann Full-time/part-time Employee Carrie Brachmann Stock Shareholder (directly Celgene Corporation purchased) Carrie Brachmann Stock Shareholder (directly Gilead Sciences purchased) Michael Brada Consultant BMS, Cellex Michael Brada Other (explain): Boehringer, Pfizer Jeffrey Bradley Consultant Varian, ViewRay Grant Jeffrey Bradley Grants/Research Support Mevion Julie Brahmer Consultant Bristol-Myers Squibb (uncompensated), Celgene, Lilly, MedImmune/AstraZeneca Julie Brahmer Grants/Research Support (Contracted Research): Bristol-Meyers Squibb, MedImmune/AstraZeneca, Merck Julie Brahmer Other (explain): Consulting Fees: Celgene, Lilly, Merck Julie Brahmer Other (explain): Non-Compensated Consulting: Bristol- Meyers Squibb George Braileanu Full-time/part-time Employee employee of Adelphi, the company paid by Amgen to conduct this study Fadi Braiteh Consultant Eli Lilly and Company Fabrice Branle Full-time/part-time Employee Novartis Joerg Bredno Full-time/part-time Employee Roche Thomas Brodowicz Other (explain): Amgen, Bayer, Eisai, Novartis, PharmaMar, Roche (Lecture Fees & Advisory Board Robert Brody Full-time/part-time Employee FT employee of AstraZeneca Robert Brody Stock Shareholder (directly AstraZeneca purchased) Dennis Brown Other (explain): DelMar Pharmaceuticals, Inc. Wolfgang Brueckl Honoraria Astra Zeneca, Boehringer Ingelheim, Lilly, Roche Alessio Bruni Grants/Research Support Tecnologie Avanzate Rolf Bruns Full-time/part-time Employee Merck Richard Bryce Full-time/part-time Employee Puma Biotechnology Inc. Lukas Bubendorf Grants/Research Support Roche, MSD Lukas Bubendorf Honoraria Roche, Novartis, AstraZeneca, MSD, Boehringer Ingelheim, BMS, Clovis Lukas Bubendorf Stock Shareholder (directly Roche, Novartis purchased) Franz Buchberger Grants/Research Support Grants of Pharmaceutical Companies for the Work of Patient Advocacy Group Raphael Bueno Grants/Research Support Verastem, Genentech, Myriad Genetics, Inc., Novartis, Siemens Healthcare Diagnostics, Exosome Diagnostics, Castle Biosciences Raphael Bueno Honoraria Siemens Healthcare Diagnostics, Myriad 8

Genetics, Inc. Raphael Bueno Other (explain): Siemens Healthcare Diagnostics, Myriad Genetics, Inc. Claudia Bühnemann Full-time/part-time Employee Boehringer Ingelheim Claudia Bühnemann Full-time/part-time Employee Boehringer Ingelheim Pharma GmbH & Co KG Biberach, Germany Paul Bunn, Jr. Consultant AstraZeneca, Boehringer Ingelheim, BMS, Celgene, Daiichi, Eisai, Genentech, Merck, Novartis, Amgen, Sanofi,Pfizer Paul Bunn, Jr. Grants/Research Support NCI, Astra Zeneca Lea Burke Full-time/part-time Employee AstraZeneca Thomas Burke Full-time/part-time Employee Merck & Co. INC Donald Bushnell Grants/Research Support Critical Path Institute Lauren Byers Consultant AbbVie, AstraZeneca, Biomarin, BioMarin Averett Pharmaceutical Inc., Eli Lilly and Company, Humana, LUNGevity, Medivation, Inc. Lauren Byers Grants/Research Support Takeda Averett Lauren Byers Other (explain): Astex Therapeutics (Scientific Advisory Averett Committee Member), AstraZeneca Pharmaceuticals (Scientific Advisory Committee Member), StemCentrx (Scientific Advisory Committee Member) Vincent Caillet Grants/Research Support Varian Medical Systems John Calaway Full-time/part-time Employee Inivata Emiliano Calvo Consultant Novartis, GSK, Astellas, Roche/Genentech, Lilly, Nanobiotich, Pfizer Emiliano Calvo Grants/Research Support Boehringer Ingelheim, Roche/Genetech, BMS, Novartis, PsiOxus, Janssen, Eisai, Abbvie, OncoMed, PharmaMar, Puma, Spectrum, Sanofi, Lilly, Pfizer, Merck, Nektar, Millenium Emiliano Calvo Other (explain): (travel, accomodations, expenses): Lilly, PsiOxus, Novartis Emiliano Calvo Speakers Bureau Novartis D. Ross Camidge Consultant Clovis Oncology D. Ross Camidge Grants/Research Support ARIAD Pharmaceuticals, Inc. D. Ross Camidge Honoraria ARIAD Pharmaceuticals, Inc., Roche/Genetech Meghan Campo Consultant Boehringer Ingelheim Paulo Campregher Full-time/part-time Employee Foundation Medicine Paulo Campregher Stock Shareholder (directly Foundation Medicine purchased) Mireille Cantarini Full-time/part-time Employee AstraZeneca Mireille Cantarini Stock Shareholder (directly AstraZeneca purchased) Pamela Cantrell Full-time/part-time Employee Protea Biosciences, Inc. Xiting Cao Full-time/part-time Employee Merck & Co Frederico Cappuzzo Consultant Roche, Clovis, Pfizer, Lilly 9

Frederico Cappuzzo Honoraria Roche, Clovis, Pfizer Frederico Cappuzzo Other (explain): (personal fees): BMS David Carbone Consultant Genentech David Carbone Honoraria Astra Zeneca, Bayer Health Care, Biocept, Biothera, Boehringer Ingelheim, Bristol Myers-Squibb, Clovis Oncology, Genentech/Roche, Guardant Health, Inviata, Janssen Diagnostics, Merck, Novartis, Pfizer, Teva Pharmaceuticals Scott Caroen Full-time/part-time Employee EpicentRx, Inc John Carpten Other (explain): Founder: Ashion Analytics, LLC Corey Carter Honoraria Bristol-Myers Squibb Silvio Cavuto Other (explain): Biostatistician at Yghea Srl - Bologna - Italy, which is a CRO dealing with study design and statistical analysis for Roche. Marie Cawkwell Full-time/part-time Employee employee of Adelphi, the company paid by Amgen to conduct this study Fabiola Cecchi Full-time/part-time Employee Nantomics Maurizio Ceppi Full-time/part-time Employee Roche Maurizio Ceppi Stock Shareholder (directly Roche purchased) Robert Cerfolio Other (explain): Intuitive Surgical, Ethicon, Community Health Systems, Myriad Genetics. Inc., Davol/BARD, Covidien/ Medtronic, KCI, an Acelity Company, Bovie Medical and C- SATS. Jamie Chaft Consultant AstraZeneca, Genentech Vikram Chand Full-time/part-time Employee Boehringer Ingelheim; EMD Serono Vikram Chand Grants/Research Support Boehringer Ingelheim; EMD Serono Vikram Chand Other (explain): Leadership - Boehringer Ingelheim; EMD Serono, Other Relationship - Boehringer Ingelheim; EMD Serono, Travel, Accommodations, Expenses - Boehringer Ingelheim; EMD Serono Vikram Chand Stock Shareholder (directly Stock and Other Ownership Interests - purchased) Bristol-Myers Squibb Jason Chandler Consultant BMS, Janssen, Caris Jason Chandler Other (explain): (travel, accomodations, expenses): BMS, Janssen, Caris I-Fen Chang Full-time/part-time Employee Bristol-Myers Squibb I-Fen Chang Stock Shareholder (directly Bristol-Myers Squibb purchased) Joe Chang Grants/Research Support Varian Medical System Joe Chang Honoraria Varian Medical System Joe Chang Stock Shareholder (directly Global Oncology One purchased) Bo Chao Full-time/part-time Employee Eli Lilly and Company Bo Chao Stock Shareholder (directly Eli Lilly purchased)

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Bo Chao Stock Shareholder (directly Eli Lilly and Company purchased) Bo Chao Stock Shareholder (directly Eli Lilly and Company purchased) Grace Chao Full-time/part-time Employee Eli Lilly and Company Heman Chao Full-time/part-time Employee Helix BioPharma Corp. Richard Chao Full-time/part-time Employee Mirati Therapeutics Richard Chao Full-time/part-time Employee Mirati Therapeutics Amanda Chargin Full-time/part-time Employee IncellDx Archana Chaudhary Full-time/part-time Employee Eli Lilly and Company Archana Chaudhary Stock Shareholder (directly Eli Lilly and Company purchased) Pierre Chauvin Honoraria Bristol-Myers Squibb Sant Chawla Consultant Amgen, Cytrx, Novartis, Janssen Sant Chawla Grants/Research Support Amgen, Cytrx, Janssen, Eisai Daniel Chen Full-time/part-time Employee Genentech Daniel Chen Stock Shareholder (directly Roche purchased) Franklin Chen Speakers Bureau Celgene; Onyx Isan Chen Full-time/part-time Employee Mirati Therapeutics Lieping Chen Consultant AstraZeneca, NextCure, Pfizer, GenomiCare and Johnson & Johnson Lieping Chen Grants/Research Support Boehringer Ingelheim, Pfizer and NextCure Shuquan Chen Full-time/part-time Employee Daiichi Sankyo Shuquan Chen Stock Shareholder (directly Daiichi Sankyo purchased) Yen-Wen Chen Full-time/part-time Employee HealthCore Inc. Haiying Cheng Honoraria AstraZeneca, Boehringer Ingelheim, Clovis Mindy Cheng Full-time/part-time Employee Roche Molecular Systems Paul Ning Cheng Stock Shareholder (directly Bio-Cancer Treatment International Limited Man purchased) Busyamas Chewaskulyong Other (explain): Roche diagnostic company provide the cyfra test Alberto Chiappori Consultant Ariad, Clovis, Genentech Alberto Chiappori Speakers Bureau Boehringer Ingelheim, Genentech, Pfizer, Merck, Novartis, Celgene Barrett Childs Full-time/part-time Employee Bayer HealthCare Pharmaceuticals Inc Marc Chioda Full-time/part-time Employee Pfizer Marc Chioda Stock Shareholder (directly Pfizer purchased) Lucian Chirieac Consultant Merck: advisory role Lucian Chirieac Other (explain): 1. Expert testimony: Shook, Hardy and Bacon and Willcox and Savage, Advisory for Merck, expert testimony:Shook, Hardy and Bacon and Wilcox and Savage, Medical Science Affiliates – Scientific Expertise 11

Oana Chirita Full-time/part-time Employee Bristol-Myers Squibb Oana Chirita Full-time/part-time Employee Bristol-Myers Squibb Juliann Chmielecki Full-time/part-time Employee Foundation Medicine Byoung Chul Cho Consultant Novartis, AstraZeneca, Pfizer, Celgene, Boeringer-Ingelheim Byoung Chul Cho Grants/Research Support Novartis, AstraZeneca, Bayer, Boeringer- Ingelheim Byoung Chul Cho Honoraria Novartis, AstraZeneca, Pfizer, Celgene, Boeringer-Ingelheim Mi Rim Choi Full-time/part-time Employee Christos Chouaid Consultant BMS, MSD, Roche, Astra Zeneca, Lilly Christos Chouaid Grants/Research Support BMS, MSD, Roche, Astra Zeneca Christos Chouaid Honoraria Bristol-Myers Squibb Christos Chouaid Other (explain): In the past 5 years, Christos Chouaid received fees for attending scientific meetings, speaking, organizing research or consulting from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Hoffman la Roche, Astra Zeneka, Sanofi Aventis, Lilly, Novartis, B Nadia Chouaki Full-time/part-time Employee Eli Lilly and Company, Neuilly-sur-Seine, France Laura Chow Consultant Adept Field Solutions, Amgen, Bio Connections, Bionest, BioStrategies Group, BMS, KeyQuest, Navigant Laura Chow Consultant Novartis, Merck, Amgen, Emergent, Astellas Laura Chow Grants/Research Support Genentech, ventiRx, Pfizer, Novartis, Merck, Incyte, NCCN/GSK, Imclone/Lily, Medimmune/AstraZeneca, BMS Laura Chow Honoraria Novartis, Merck, Amgen, Emergent, Astellas Laura Chow Other (explain): (travel, accomodations, expenses): Novartis, Merck Laura Chow Other (explain): Genzyme, Merck Sharp & Dohme, Seattle Genetics Laura QM Chow Grants/Research Support Novartis, Bristol-Myers Squibb, Merck, Eli lilley/Imcloce, OSI Pharma, Genentech, VentiRx, Pfizer, GSK, AstraZeneca/MedImmune, Incyte, NCCN/GSK Laura QM Chow Other (explain): Consulting/Advisory: Novartis, Bristol- Myers Squibb, Merck, Emergent BioSolutions, Seattle Genetics, Sanofi Genzyme James Christensen Full-time/part-time Employee Mirati Therapeutics Jared Christensen Other (explain): Riverain Technologies, LLC Daniel Christoph Other (explain): travelling grants which I got from Roche. Daniel Christoph Speakers Bureau Chugai, Roche Darya Chudova Full-time/part-time Employee Guardant Health, Inc Chin-Hee Chung Full-time/part-time Employee Pfizer Inc

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Chin-Hee Chung Stock Shareholder (directly Pfizer Inc purchased) Fortunato Ciardiello Consultant Astrazeneca, Bayer, Lilly, MERK, Roche, Serono Tudor Ciuleanu Consultant Amgen, AstraZeneca, Boehringer- Ingelheim, Bristol-Myers-Squibb, Roche, Pierre-Fabre, Eli Lilly and Company, Merck, MSD, Pfizer Tudor Eliade Ciuleanu Full-time/part-time Employee Institutul Oncologic Prof. Dr. Ion Chiricuta Tudor Eliade Ciuleanu Honoraria Advisory board and/ or speaker: Astellas, Amgen, AstraZeneca, Bristol Myers Squibb, Janssen, Eli Lilly, Merck, Merck Sharp and Dohme, Pfizer, Roche, Boehringer Ingelheim Tim Clackson Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. Tim Clackson Other (explain): ARIAD Pharmaceuticals, Inc. J Clancy Full-time/part-time Employee inVentiv Clinical/contractor for Pfizer James Clark Full-time/part-time Employee Inivata Emilie Clay Consultant MSD Shelley Coleman Full-time/part-time Employee Genentech Shelley Coleman Stock Shareholder (directly Roche, Gilead Sciences, Gelgeme, Teva, purchased) Merck David Collingridge Full-time/part-time Employee The Lancet Oncology David Collingridge Stock Shareholder (directly Elsevier Ltd purchased) Eric Collisson Consultant Guardant Health Eric Collisson Consultant Nantomics Eric Collisson Grants/Research Support Daiichi, Ignyta, Trovagene Caitlin Connelly Full-time/part-time Employee Foundation Medicine Stephen Coons Grants/Research Support Patient-reported Outcome Consortium Wendy Cooper Grants/Research Support Merck Sharp & Dohme (Australia) Wendy Cooper Honoraria Astra Zeneca, Bristol Myers Squibb, Merck Sharp & Dohme (Australia), Pfizer Catherine Copigneaux Full-time/part-time Employee Daiichi Sankyo Catherine Copigneaux Stock Shareholder (directly Daiichi Sankyo purchased) Romain Corre Consultant Lilly, Pfizer, Roche, Boeehringer-Ingelheim Alexis Cortot Consultant Novartis, Pfizer, Roche Alexis Cortot Consultant Roche, Pfizer, Novartis, Boehringer- Ingelheim Alexis Cortot Honoraria Alexis Cortot Honoraria Alexis Cortot Honoraria Novartis, Pfizer, Roche, Astra-Zeneca and Boehringer-Ingelheim, Eli Lilly and Company, Merck, Pfizer Daniel Costa Consultant Boehringer Ingelheim and Ariad pharmaceuticals, Pfizer

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Daniel Costa Honoraria ARIAD Pharmaceuticals, Inc. François- Cotté Full-time/part-time Employee Bristol-Myers Squibb Emery Bruno Coudert Honoraria Roche Sébastien Couraud Honoraria Roche David Craig Other (explain): Founder: Ashion Analytics, LLC Jeffrey Crawford Grants/Research Support Amgen Alan Crim Consultant AstraZeneca Lucio Crinò Consultant Novartis, AstraZeneca and Pfizer Lucio Crinò Honoraria Novartis, AstraZeneca and Pfizer Lucio Crinò Other (explain): serves on advisory board of BMS , Boehringer Ingelheim, Pfizer during the conduct of the study Elisabeth Croft Full-time/part-time Employee AstraZeneca Agnieszka Cseh Full-time/part-time Employee Boehringer Ingelheim RCV GmbH & Co. KG Tanja Cufer Consultant Boehringer Ingelheim, BMS, Pfizer J. Jean Cui Full-time/part-time Employee TP Therapeutics, Inc. Xiaoming Cui Full-time/part-time Employee Novartis Xiaoming Cui Stock Shareholder (directly Novartis purchased) Kenneth Culver Full-time/part-time Employee Novartis Craig Cummings Full-time/part-time Employee Genentech Craig Cummings Stock Shareholder (directly Roche purchased) David Currow Consultant Mayne Pharma, Specialist Therapeutics Australia Pty.Ltd. David Currow Other (explain): Intellectual Property Mayne Pharma Akos Czibere Full-time/part-time Employee Merrimack Pharmaceuticals Anand Dalal Full-time/part-time Employee Novartis Rita Dalal Full-time/part-time Employee Eli Lilly and Company Rita Dalal Stock Shareholder (directly Eli Lilly and Company purchased) Mercedes Dalurzo Other (explain): I received honoraria as speaker and Liliana consultand in advisory boards and teaching activities related with lung cancer molecular test for Pfizer and Novartis Tapashi Dalvi Full-time/part-time Employee AstraZeneca Tapashi Dalvi Stock Shareholder (directly AstraZeneca, Achillion, Gilead, Inovio, purchased) BMS, Roche, Medivation Thomas D'Amico Consultant Scanlan International Inc. Kathleen Danenberg Full-time/part-time Employee liquid genomics Peter Danenberg Full-time/part-time Employee liquid genomics Cheufou Danjouma Other (explain): Proctor; I am Proctor thoracic robotic surgery Eric Dansin Consultant BMS, ROCHE; LILLY, NOVARTIS 14

Eric Dansin Grants/Research Support Roche Eric Dansin Honoraria from Novartis, Pfizer, Roche, Astra-Zeneca, Lilly, Boehringer-Ingelheim Eric Dansin Honoraria Novartis, Pfizer, Astra Zeneca, Roche Eric Dansin Other (explain): Advisory board or board of directors: Bristol Myers Squibb, Roche, Lilly, Novartis Rahul Das Consultant Quantum Si Mads Daugaard Other (explain): I am founder, shareholder, and chairman of the board of directors in VAR2 Pharmaceuticals, which is the commercialization vehicle for rVAR2-based therapeutics and diagnostics. Melinda Daumont Full-time/part-time Employee Bristol-Myers Squibb Melinda Daumont Full-time/part-time Employee Bristol-Myers Squibb Anthony Davies Stock Shareholder (directly Biocroi Ltd. purchased) Marianne Davies Speakers Bureau Genentech, Merck, BMS, Astra Zenica Farshid Dayyani Full-time/part-time Employee Roche Diagnostics Farshid Dayyani Speakers Bureau Genentech Filippo De Braud Consultant Merck Serono, Eli Lilly, GSK, MSD, Novartis, BMS, Servier Gilberto De Castro Jr Consultant Novartis, Roche, MSD Gilberto De Castro Jr Honoraria MSD Gilberto De Castro Jr Other (explain): Advisory: Novartis Gilberto De Castro Jr Speakers Bureau AstraZeneca, MSD, BMS Harry de Koning Grants/Research Support The NELSON trial is supported by: ‘Zorg Onderzoek Nederland-Medische Wetenschappen’(ZonMw), ‘KWF Kankerbestrijding’, ‘Stichting Centraal Fonds Reserves van Voormalig Vrijwillige Ziekenfondsverzekeringen’ (RVVZ) Gilberto De Lima Lopes Honoraria Sanofi Aventis, Lilly, Pfizer, Roche, BMS, MSD, Merck-Serono, Boehringer Ingelheim, Astra Zeneca Ramon De Mello Consultant Pfizer Andrade Ramon De Mello Consultant Zodiac Andrade Ramon De Mello Speakers Bureau Astrazeneca Andrade Ramon De Mello Speakers Bureau Novartis Andrade Cisio De Oliveira Brandao Full-time/part-time Employee Amgen Inc. Cisio De Oliveira Brandao Stock Shareholder (directly Amgen Inc. purchased) Luigi De Petris Consultant F. Hoffmann-La Roche Ltd, Novartis Luigi De Petris Other (explain): Consultant/lectures: F. Hoffman La Roche Ltd; Novartis Didier Debieuvre Honoraria Bristol-Myers Squibb

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Kendra Debusk Full-time/part-time Employee Genentech/Roche Kendra Debusk Stock Shareholder (directly Genentech/Roche purchased) Roy Decker Grants/Research Support Merck & Co, Inc Steve Demas Full-time/part-time Employee Helix BioPharma Corp. Neelima Denduluri Grants/Research Support Amgen, Genetech, Novartis Wei Deng Full-time/part-time Employee TP Therapeutics, Inc. Youping Deng Full-time/part-time Employee AbbVie Youping Deng Stock Shareholder (directly AbbVie, may own stock purchased) Yu Deng Full-time/part-time Employee Genentech Phillip Dennis Full-time/part-time Employee AstraZeneca Henrik Depenbrock Full-time/part-time Employee Lilly Deutschland GmbH Hirak Der-Torossian Full-time/part-time Employee Mirati Therapeutics Bhardwaj Desai Full-time/part-time Employee Astellas Darrin Despain Full-time/part-time Employee Clovis Frank Detterbeck Grants/Research Support Medela Frank Detterbeck Other (explain): Olympus (Member of a DSMB for a research study) Diana Devincenzo Full-time/part-time Employee AstraZeneca Jennifer Devlen Full-time/part-time Employee ICON Clinical Research Joseph Diaz Full-time/part-time Employee Guardant Health, Inc Peter Dickinson Honoraria Boehringer-Ingelheim Peter Dickinson Speakers Bureau Elekta Maximilian Diehn Consultant Roche Anne-Marie Dingemans Other (explain): Advisory board or board of directors: Roche Adrien Dixmier Consultant Bristol-Myers Squibb Adrien Dixmier Consultant MSD Adrien Dixmier Consultant Novartis Nigel Dodd Full-time/part-time Employee Boehringer-Ingelheim Robert Doebele Other (explain): ARIAD Pharmaceuticals, Inc. Fatma Doener Full-time/part-time Employee CureVac AG Cécile Dorange Full-time/part-time Employee Bristol-Myers Squibb Cécile Dorange Stock Shareholder (directly Bristol-Myers Squibb purchased) Afshin Dowlati Consultant Boehringer Ingelheim Afshin Dowlati Consultant Seattle Genetics Afshin Dowlati Grants/Research Support Amgen Afshin Dowlati Grants/Research Support Bristol-Myers Squibb, EMD Serono, Lilly/ImClone, MedImmune, OncoMed Robert Downey Stock Shareholder (directly Protea Biosciences Inc purchased)

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Alex Drilon Grants/Research Support Foundation Medicine Alexander Drilon Honoraria Exelixis Elizabeth Dudnik Consultant Boeringer Ingelheim Elizabeth Dudnik Honoraria MSD, Roche, Astra Zeneca, Boeringer Ingelheim Elizabeth Dudnik Other (explain): ROCHE, MSD, ASTRAZENICA Emily Duffield Speakers Bureau Merck, Boerhinger, Astra Zenica Gary Dukart Consultant Xcovery Holding Company Nicholas Dupuis Full-time/part-time Employee Biodesix, Inc. Nicholas Dupuis Stock Shareholder (directly Biodesix, Inc. purchased) Isabelle Durand-Zaleski Honoraria Bristol-Myers Squibb Bradley Durham Full-time/part-time Employee Inivata Addie Dvir Full-time/part-time Employee Teva Addie Dvir Other (explain): Employee of Oncotest (subsidiary of Teva pharmaceuticals), the distributor of Guardant360 in Israel Scott Dylla Full-time/part-time Employee AbbVie Stemcentrx Rafal Dziadziuszko Consultant Roche, Pfizer, Novartis, Boehringer- Ingelheim Beth Eaby-Sandy Consultant Amgen, Boehringer-Ingelheim, Celgene, Eli Lilly, Genentech, Merck, Synta, VentiRx Brandon Early Full-time/part-time Employee Heat Biologics James Eaton Other (explain): Consultancy Fee, JE works for ICON Plc an international consultancy firm and has received funding from a number of companies including Eli Lilly and Co Wilfried Eberhardt Consultant Novartis, BMS, Merck, Bayer, Pfizer, Roche, AstraZeneca, Boehringer- Ingelheim, Amgen, Celgene, Lilly, Daichi Sankyo Joseph Paul Eder Honoraria Merck Eva Ehrnrooth Full-time/part-time Employee Boehringer-Ingelheim Danmark AS Lawrence Einhorn Consultant Celgene Lawrence Einhorn Stock Shareholder (directly AMGEN and Biogenidec purchased) François Eisinger Honoraria Roche Cem Elbi Full-time/part-time Employee Bayer HealthCare Pharmaceuticals Inc Peter Ellis Other (explain): Celgene (DSMC member) Helmy Eltoukhy Other (explain): Co-founder, stock holder, and employee of Guardant Health Julia Elvin Full-time/part-time Employee Foundation Medicine Julia Elvin Stock Shareholder (directly Foundation Medicine purchased) Masahiro Endo Honoraria AstraZeneca K.K., Ono Pharamaceutical Co., Ltd. Christine Engel Full-time/part-time Employee Roche Diagnostics

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Walburga Engel-Riedel Consultant Novartis Walburga Engel-Riedel Honoraria Novartis, Lilly, Boehringer-Ingelheim, Roche Edell Eric Consultant Olympus America, Educational Curriculum Design Susan Erickson-Viitanen Full-time/part-time Employee Incyte Corporation Mark Erlander Full-time/part-time Employee Trovagene Bruno Escarguel Grants/Research Support Novatech Janet Espirito Full-time/part-time Employee McKesson Specialty Health David Ettinger Consultant ARIAD Pharmaceuticals, Inc., Boehringer Ingelheim, BMS, Eli Lilly & Co., EMD Serono, Genentech, Corp., Helsinn Therapeutics, Inc., Herron Therapeutics, Trovagene, Inc. David Ettinger Grants/Research Support Golden Biotech David Ettinger Other (explain): Ariad, Boehringer Ingelheim, Bristol-Meyers Squibb, Eli Lilly, EMD Serono, Genetech, Golden Biotech, Helsinn Therapeutics, Trovagene Brent Evans Full-time/part-time Employee Myriad Genetic Laboratories, Inc. Brent Evans Stock Shareholder (directly Myriad Genetic Laboratories, Inc. purchased) Jeffry Evans Consultant Bristol-Myers Squibb, Baxter, Karus Therapeutics, Eisai Jeffry Evans Grants/Research Support AstraZeneca, Celgene, Eisai, PSK, Roche, Basilea, e-Therapeutics, Immunocore, Vertex, Merck, Daiichi Sankyo, Bristol- Myers Squibb Jeffry Evans Honoraria Bristol-Myers Squibb Jeffry Evans Other (explain): (travel, accomodations, expenses): Bristol- Myers Squibb, Celgene Jeffry Evans Speakers Bureau Bristol-Myers Squibb, Celgene Rachel Evans Other (explain): Consultancy Fee, RE works for ICON Plc an international consultancy firm and has received funding from a number of companies including Eli Lilly and Co David Fabrizio Full-time/part-time Employee Foundation Medicine David Fabrizio Stock Shareholder (directly Foundation Medicine purchased) Stephen Fairclough Full-time/part-time Employee Guardant Helath Corinne Faivre-Finn Grants/Research Support Merck, Astra Zeneca Demiana Faltaos Consultant Arena Pharmaceuticals Demiana Faltaos Full-time/part-time Employee Mirati Therapeutics Demiana Faltaos Stock Shareholder (directly Arena Pharmaceuticals purchased) Jean Fan Full-time/part-time Employee Boehringer Ingelheim Xiaolin Fan Full-time/part-time Employee AbbVie Xiaolin Fan Stock Shareholder (directly AbbVie, may own stock purchased)

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Xin Fang Full-time/part-time Employee ACEA Pharmaceutical Research, Hangzhou, China, and ACEA Biosciences Inc. San Diego, USA Ori Farber Full-time/part-time Employee Novocure Nathalie Faye Full-time/part-time Employee MEDIAN Technologies Kenneth Fearon Consultant Helsinn Kenneth Fearon Grants/Research Support Helsinn Kenneth Fearon Honoraria Helsinn Enriqueta Felip Consultant BMS Enriqueta Felip Consultant Boeheringer Ingelheim, MSD, Eli Lilly, Roche, Pfizer, Novartis, BMS, Celgene Enriqueta Felip Consultant Eli Lilly, Pfizer, Roche, Boehringer Ingelheim, MSD Enriqueta Felip Grants/Research Support BMS, Novartis, Roche Enriqueta Felip Honoraria Astra Zeneca, Boeheringer Ingelheim, MSD, Eli Lilly, Roche, Pfizer, Novartis, BMS, Celgene Enriqueta Felip Other (explain): Advisory board: Eli Lilly, Pfizer, Roche, MSD, Boehringer Ingelheim Enriqueta Felip Other (explain): Lecture fees: Astra Zeneca, BMS, Novartis Enriqueta Felip Speakers Bureau AstraZeneca, Bristol-Myers Squibb, Novartis, Roche Dean Fennel Honoraria Clovis, Medimmune, Bayer, Aduro, MSD, Boehringer Ingelheim (Advisory Board) Dean Fennel Speakers Bureau BMS, AZ, MSD Ancilla Fernandes Full-time/part-time Employee AstraZeneca Jérôme Fernandes Honoraria Bristol-Myers Squibb Geri Ferraro Full-time/part-time Employee Merck & Co., Inc. Gilbert Ferretti Honoraria Boehringer, Roche Joachim Ficker Honoraria Astra Zeneca, Boehringer Ingelheim, Lilly, Merck, Roche Panos Fidias Consultant Boehringer-Ingelheim Panos Fidias Speakers Bureau Boehringer-Ingelheim; Bristol Myers Squibb Robert Figlin Consultant Novartis, Pfizer Robert Figlin Grants/Research Support BMS, Peloton, GSK, Argos, Exelixis, Cerulean Martin Filipits Speakers Bureau Honoraria as Speakers and/or Advisory Boards from AstraZeneca, Boehringer Ingelheim, MSD, Novartis, Roche Joseph Fiore Full-time/part-time Employee Merck Jonathan Fitzgerald Full-time/part-time Employee Merrimack Pharmaceuticals Jonathan Fitzgerald Stock Shareholder (directly Merrimack Pharmaceuticals purchased) Javier Flandes Consultant Medtronic Tanya Fleege Full-time/part-time Employee Astellas Pharma Global Development Alex Fleishman Full-time/part-time Employee Amgen Inc.

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Alex Fleishman Stock Shareholder (directly Amgen Inc. purchased) Emuella Flood Full-time/part-time Employee ICON Clinical Research Susan Flynn Full-time/part-time Employee Genentech Erik Folch Consultant Boston Scientific Erik Folch Consultant Medtronic Erik Folch Consultant Olympus Rachel Fonstad Full-time/part-time Employee Roche Patrick Forde Grants/Research Support AstraZeneca/MedImmune Patrick Forde Grants/Research Support BMS, Medimmune/AstraZeneca, Kiowa, Novartis Patrick Forde Other (explain): Advisory Board Member (Uncompensated): AstraZeneca, Boehringer-Ingelheim, Celgene, EMD-Serono, Novartis Patrick Forde Other (explain): Uncompensated advisory board member for AstraZeneca, Celgene, Novartis, Boehringer-Ingelheim, EMD-Serono Tim Forshew Full-time/part-time Employee Inivata Paul Foster Full-time/part-time Employee Genentech, Inc. Rebekah Foster Other (explain): I am an employee of Analysis Group. Analysis Group has received funding from Novartis to partner on this study. Ceritinib is Novartis' product. Rebekah Foster Other (explain): I am an employee of Analysis Group. Analysis Group has received funding from Novartis to partner on this study. Ceritinib is Novartis' product. Mariola Fotin-Mleczek Full-time/part-time Employee CureVac AG Bernard Fox Other (explain): UbiVac; Co-Founder, President and CEO; Equity Interest Sephen Fox Grants/Research Support Merck Sharp & Dohme (Australia) Sephen Fox Honoraria Merck Sharp & Dohme (Australia) Garrett Frampton Full-time/part-time Employee Foundation Medicine Garrett Frampton Stock Shareholder (directly Foundation Medicine purchased) Wilbur Franklin Grants/Research Support BMS Kevin Franks Honoraria Boehringer-Ingelheim, Oncology Forum Kevin Franks Speakers Bureau Elekta Janet Freeman-Daily Honoraria Ignyta, AstraZeneca, Oncothyreon, Oncogenex Klaus Freivogel Full-time/part-time Employee United BioSource Corporation John Friend Full-time/part-time Employee Helsinn Therapeutics (US), Inc. Bente Frimodt-Moller Full-time/part-time Employee Eli Lilly and Company Yutaka Fujiwara Consultant ONO Yutaka Fujiwara Grants/Research Support AstraZenaca Yutaka Fujiwara Grants/Research Support AstraZeneca, Chugai, Eisai, Eli Lilly, MSD, Daiichi-Sankyo 20

Yutaka Fujiwara Speakers Bureau ONO, BMS Masahiro Fukuoka Consultant Astellas Pharma Inc,. Eisai Co Ltd., Ono Pharm. Co. Ltd., Daichi Samkyo Co. Ltd., Sumitomo Dainippon Co. Ltd. Masahiro Fukuoka Honoraria Kyowa Hakko Kirin Co. Ltd., Chugai Pharm. Co Ltd. Roel Funke Full-time/part-time Employee Genentech Roel Funke Stock Shareholder (directly Genentech purchased) Marta Gabasa Grants/Research Support Boheringer-Ingelheim Shirish Gadgeel Consultant Ariad, Astra-Zeneca, BMS, Boehringer Ingelheim, Genentech/Roche, Pfizer, Novartis, Shirish Gadgeel Grants/Research Support Roche, Janssen, Astra-Zeneca, Merck, Pfizer, Millenium, Clovis, Novartis, Halozyme, Acerta Shirish Gadgeel Other (explain): Advisory board or board of directors: Genentech/Roche, ARIAD, Novartis, Boehringer-Ingelheim Shirish Gadgeel Speakers Bureau Astra-Zeneca Julia Gage Other (explain): Amgen Inc. Davina Gale Full-time/part-time Employee Inivata Davina Gale Full-time/part-time Employee Inivata Philip Galebach Other (explain): I am an employee of Analysis Group. Analysis Group has received funding from Novartis to partner on this study. Ceritinib is Novartis' product. Frank Gan Full-time/part-time Employee Eli Lilly and Company Frank Gan Stock Shareholder (directly Eli Lilly and Company purchased) David R. Gandara Consultant AstraZeneca, Genentech, Pfizer, BMS, Boehringer Ingelheim, Eli Lilly, EMD Serrano, Guardant Health, MERCK David R. Gandara Grants/Research Support AstraZeneca, Bristol-Myers Squibb, Genentech, Eli Lilly and Company, EMD Serrano, MERK Leena Gandhi Consultant Astra-Zeneca, Abbvie, Merck, Genentech- Roche, Pfizer Leena Gandhi Consultant Merck, Astra-Zeneca, Pfizer, Abbvie, Genentech-Roche Leena Gandhi Grants/Research Support Merck, Genentech/Roche, Astra-Zeneca, Abbvie, Pfizer, Bristol-Myers Squibb Leena Gandhi Honoraria Merck Leena Gandhi Other (explain): Travel, accommodation, expenses: Merck, Bristol-Myers Squibb Mayank Gandhi Full-time/part-time Employee Genentech, Inc. Apar Ganti Consultant Pfizer Apar Ganti Grants/Research Support Amgen, BMS, Janssen, Merck, NewLink Genetics, Pfizer Lianju Gao Grants/Research Support Novogene Bioinformatics Institute Marina Garassino Consultant Eli Lilly, Astra Zeneca, BMS, MSD, Roche, 21

Celgene Marina Garassino Grants/Research Support Pfizer Jacob Garcia Full-time/part-time Employee Amgen Jacob Garcia Stock Shareholder (directly Amgen purchased) Rosario García Campelo Consultant Novartis Rosario García Campelo Consultant Novartis Edward Garon Grants/Research Support AstraZeneca, Boehringer-Ingelheim, Bristol-Myers Squibb, Eli Lilly, Genentech, Merck, Novartis, Pfizer Pilar Garrido Consultant Roche, Astra-Zeneca, Eli Lilly and Company, Celgene and BMS Pilar Garrido Honoraria Eli Lilly and Company Pilar Garrido Honoraria Roche, Astra-Zeneca, Eli Lilly and Company; Pfizer, Sanofi, MSD, Boehringer Ingelheim and Novartis Jennifer Garst Consultant Arian Jennifer Garst Other (explain): Lung Cancer Initiative of North Carolina Jennifer Garst Speakers Bureau Biodesix Anne- Gaudin Full-time/part-time Employee Bristol-Myers Squibb Françoise Laurie Gay Full-time/part-time Employee Foundation Medicine Laurie Gay Stock Shareholder (directly Foundation Medicine purchased) Joy Ge Full-time/part-time Employee Merck Joy Ge Stock Shareholder (directly Merck purchased) Sarayut Geater Consultant Boehringer Ingelheim, Novartis Sarayut Geater Grants/Research Support Boehringer Ingelheim, Novartis, AstraZenaca, Roche, Eisai, Teva Sarayut Geater Honoraria Boehringer Ingelheim, Novartis, AstraZenaca William Geese Full-time/part-time Employee BMS William Geese Other (explain): (travel, accomodations, expenses): BMS William Geese Stock Shareholder (directly BMS purchased) Tom Geldart Speakers Bureau BMS, Pfizer Yuan Geng Full-time/part-time Employee Boehringer Ingelheim (China) Investment Co., Ltd. Ryan Gentzler Consultant Clovis Oncology Ryan Gentzler Grants/Research Support Merck, Bristol-Myers Squibb Peter Georgantopoulos Consultant StraMarTec Inc. Ben George Consultant Celgene David Gerber Grants/Research Support Immunogen, ArQule, Synta, Genentech, Celgene, ImClone Systems, BerGenBio David Gerber Other (explain): (Patents, Royalties, Other Intellectual Property): Royalties from Oxford University Press from two books; Royalties from 22

Decision Support in Medicine from the Clinical Decision Support—Oncology on- line program David Gerber Other (explain): (Travel, Accommodations, Expenses): Lilly, ArQule, Lilly David Gerber Stock Shareholder (directly Gilead Sciences purchased) Scott Gettinger Consultant ARIAD Pharmaceuticals, Inc., BMS, Janssen Scott Gettinger Grants/Research Support ARIAD Pharmaceuticals, Inc., AstraZeneca/MedImmune, BMS, Boehringer Ingelheim, Incyte, Pfizer, Roche/Genentech Serban Ghiorghiu Full-time/part-time Employee AstraZeneca (personal and spouse) Serban Ghiorghiu Stock Shareholder (directly AstraZeneca (personal and spouse) purchased) Giuseppe Giaccone Grants/Research Support Incyte Corporation Giuseppe Giacconne Consultant Boehringer Ingelheim, Celgene, Clovis Giuseppe Giacconne Grants/Research Support Astra-Zeneca, Eli-Lilly, Karyopharm James Gibbons Full-time/part-time Employee Xcovery Holding Company Neil Gibson Full-time/part-time Employee Boehringer-Ingelheim Pharma GmbH Maciej Gil Full-time/part-time Employee Eli Lilly and Company Moshe Giladi Full-time/part-time Employee Novocure Stacy Gilbert Full-time/part-time Employee Oncimmune Ltd Robert Gillies Other (explain): Advisory Board, HealthMyne Inc. France Ginchereau Sowell Full-time/part-time Employee ICON Clinical Research Nicolas Girard Consultant BMS, Roche, MSD Regina Gironés Grants/Research Support ROCHE Etienne Giroux Leprieur Honoraria Novartis, AstraZeneca, Lilly Barbara Gitlitz Consultant Clovis Oncology, Ariad, Celgene, AstraZeneca Barbara Gitlitz Speakers Bureau Genentech and Lilly Sabine Glaser Full-time/part-time Employee Novartis Ulrike Gnad-Vogt Full-time/part-time Employee CureVac AG Jon Gockerman Full-time/part-time Employee Novella Clinical Chloé Godard Full-time/part-time Employee MSD John Goffin Honoraria Bristol-Myers Squibb Tuncay Goksel Grants/Research Support Lilly, AstraZeneca Tuncay Goksel Honoraria BMS, Pfizer Kathryn Gold Consultant Pfizer, Clovis Kathryn Gold Grants/Research Support ARIAD Pharmaceuticals, Inc., AstraZeneca, BMS, Puma, Roche/Genentech Kathryn Gold Grants/Research Support Pharmacyclics Kathryn Gold Honoraria BMS, Roche

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Kathryn Gold Other (explain): Astra Zeneca Sarah Goldberg Grants/Research Support Astra Zeneca Zelanna Goldberg Full-time/part-time Employee Pfizer Inc Lisa Golden Full-time/part-time Employee Eli Lilly and Company Sophie Golding Full-time/part-time Employee F. Hoffmann La Roche Ltd Sophie Golding Stock Shareholder (directly Hoffmann-La Roche purchased) Jonathan W. Goldman Consultant Bristol-Myers Squibb, Clovis Oncology, Trovagene Jonathan W. Goldman Grants/Research Support Lilly, Genentech/Roche, Astex Pharmaceuticals, Synta, Clovis Oncology, Bristol-Myers Squibb, AstraZeneca/MedImmune, Threshold Pharmaceuticals Jonathan W. Goldman Honoraria Clovis Oncology, Genentech, Bristol-Myers Squibb Jerome Goldschmidt Consultant Amgen Vinai Gondi Honoraria Novocure Michael Gordon Grants/Research Support Eli Lilly and Company, Imclone Ira Gore Grants/Research Support AstraZeneca, Bayer, Bristol-Myers, Celldex Therapeutics, Inc., Amgen, Gilead, Roche, Genentech, Halozyme Inc., TGT Therapeutics, Incyte, Galena, PSMA Development Co., PUMA, Pfizer, , Ziopharm, CAHABA, Imclone, Shire Pharmaceuticals, Novartis Glenwood Goss Honoraria AstraZeneca, Boehringer Ingelheim, BMS, Pfizer Glenwood Goss Other (explain): AstraZeneca, Boehringer Ingelheim, BMS, Pfizer (Advisory board) Koichi Goto Consultant Chugai Pharma, Daiichi Sankyo, GlaxoSmithKline, Taiho Pharmaceutical Koichi Goto Grants/Research Support Amgen, Astellas, BioPharma, Boehringer Ingelheim, Chugai Pharma, Daiichi Sankyo, Eisai, GlaxoSmithKline, Kyowa Hakko Kirin, Lilly, MSD, Novartis, Ono Pharmaceutical, OxOnc, Pfizer, Riken Genesis, Sumitomo Dainippon, Taiho Pharmaceutical, Takeda Koichi Goto Honoraria AstraZeneca, Bristol-Myers Squibb, Chugai Pharma, Daiichi Sankyo, Kyowa Hakko Kirin, Lilly, Nippon Kayaku, Novartis, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Yasushi Goto Consultant Boehringer Ingelheim, Eli Lilly, Glaxo, Claxo Smith Kline, Taiho Yasushi Goto Speakers Bureau AstraZeneca, Eli Lilly, Chugai, Taiho, Boehringer, Bristol Myers Squibb, Ono Bonnie Gould Rothberg Stock Shareholder (directly Butterfly Networks, LAM Therapeutics, purchased) Hyperfine Technologies, Quantum Si Technologies Ramaswamy Govindan Consultant GlaxoSmithKline, Boehringer-Ingelheim, Clovis Oncology, Helsinn Therapeutics, Genentech/Roche, Abbvie, Celgene, Bayer, Novartis 24

Ramaswamy Govindan Grants/Research Support Bayer, GlaxoSmithKline, MethylGene, Abbvie Ramaswamy Govindan Grants/Research Support Bayer, MethylGene, Abbvie Ramaswamy Govindan Honoraria Pfizer, Merck, Bohringer Ingelheim, Clovis, Helsinn Healthcare, Genentech, AbbVie, GSK, Celgene, Bayer, Roche, StemCentrx Ramaswamy Govindan Other (explain): Travel expenses: Celgene, Merck, Boehringer Ingelheim, Roche, AbbVie, StemCentrx Kyle Gowen Full-time/part-time Employee Foundation Medicine Kyle Gowen Stock Shareholder (directly Foundation Medicine purchased) David Grainger Full-time/part-time Employee Eli Lilly and Company David Grainger Grants/Research Support Steering Committees for Projects Funded by Eli Lilly and Company David Grainger Stock Shareholder (directly Eli Lilly and Company purchased) Richard Gralla Consultant Boehringer Ingelheim, Merck, BMS, Helsinn, Tesaro, Eisai Richard Gralla Honoraria Boehringer Ingelheim, Merck, BMS, Helsinn, Tesaro Fred Grannis Other (explain): Paolicelli and Phillps Law Firm Amanda Grattan Full-time/part-time Employee Merck Sharp & Dohme (Australia) Morten Grauslund Grants/Research Support Roche Jhanelle Gray Consultant AstraZeneca, Celgene, Eli Lilly, Boehringer Ingelheim, Merrimack Pharmaceuticals, Trovagene Jhanelle Gray Grants/Research Support Array, AstraZeneca, Merck Jhanelle Gray Speakers Bureau Genentech Emma Green Full-time/part-time Employee Inivata Danielle Greenawalt Full-time/part-time Employee AstraZeneca, Bristol Myers Squibb Phil Greenberg Consultant Juno Therapeutics Phil Greenberg Stock Shareholder (directly Juno Therapeutics purchased) Laurent Greillier Honoraria Roche Cesare Gridelli Consultant Eli Lilly, Roche , BMS, MSD, Novartis, Pfizer Cesare Gridelli Grants/Research Support Eli Lilly Cesare Gridelli Speakers Bureau Eli Lilly, BMS, Celgene,Roche Julia Grigorieva Full-time/part-time Employee Biodesix Harry Groen Consultant Eli Lilly, MSD, Roche Christian Grohé Consultant Novartis Christian Grohé Honoraria Novartis Francesco Grossi Other (explain): serves on advisory boards of BMS during the conduct of the study Francesco Grossi Speakers Bureau Eli Lilly, Roche, BMS, Astra Zeneca, Pierre Fabre, and Boehringer-Ingelheim Matthew Gubens Consultant Boehringer Ingelheim, Bristol-Myers 25

Squibb, Ariad, Clovis, Nextar Matthew Gubens Consultant Bristol-Myers Squibb, Genetech/Roche, Nektar, Pfizer Matthew Gubens Grants/Research Support Abbvie, Celegene, Roche, Merck, Novartis, Oncomed Matthew Gubens Grants/Research Support Celgene, Genentech/Roche, Merck, Novartis, OncoMed Matthew Gubens Other (explain): Travel/Accommodations: Celgene, Genentech/Roche Annie Guerin Consultant Genentech Roche Annie Guerin Other (explain): I am an employee of Analysis Group. Analysis Group has received funding from Novartis to partner on this study. Ceritinib is Novartis' product. Christoph Guetter Full-time/part-time Employee Roche Florian Guisier Honoraria Boehringer Ingelheim Anika Gupta Full-time/part-time Employee Foundation Medicine David Gustafson Full-time/part-time Employee Trovagene Martin Gutierrez Consultant Bayer, Celgene, Eli Lilly Martin Gutierrez Grants/Research Support Abbvie (Institutional research funding) Martin Gutierrez Grants/Research Support Acceleron Pharma, Bristol-Myers Squibb, Daiichi Sankyo, Eli Lilly, EMD Serono, Esanex, Gilead Sciences, Karyopharm Therapeutics, Novartis MedImmune, Rexahn Pharmaceuticals, TG Therapeutics (Institutional research funding) Martin Gutierrez Speakers Bureau Bristol-Myers Squibb Sylvia Gütz Consultant Boehringer-Ingelheim, BMS, Roche Sylvia Gütz Honoraria Boehringer-Ingelheim, BMS, Roche, Pfizer, AstraZeneca Allan Hackshaw Honoraria Boehringer Ingelheim Balazs Halmos Consultant AstraZeneca, Boehringer Ingelheim, Celgene, FoundationOne, Genentech, Pfizer, Roche Balazs Halmos Grants/Research Support AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck, Mirati Frank Haluska Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. Frank Haluska Other (explain): ARIAD Pharmaceuticals, Inc. Akinobu Hamada Grants/Research Support AstraZeneca Akinobu Hamada Grants/Research Support Chugai Chikuma Hamada Consultant Taiho Pharmaceutical CO., LTD Garret Hampton Full-time/part-time Employee Genentech, Inc. Tae Han Full-time/part-time Employee AbbVie Stemcentrx Vladimir Hanes Full-time/part-time Employee Amgen Vladimir Hanes Stock Shareholder (directly Amgen purchased) Jeff Haney Full-time/part-time Employee ARIAD Pharmaceuticals, Inc.

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Jeff Haney Other (explain): ARIAD Pharmaceuticals, Inc. Christine Hann Grants/Research Support Bristol-Myers Squibb, GlaxoSmithKline, Merrimack, Stemcentrx, Oncomed Nasser Hanna Grants/Research Support Merck, BMS Karin Hansen Consultant Boehringer Ingelheim, Eli Lilly, MSD Karin Hansen Honoraria Novartis Karin Hansen Other (explain): BMS, Boehringer Ingelheim, MSD, Pfizer David Harpole Consultant Scientific Advisory Board-Airad Ronald Harris Full-time/part-time Employee Broome Oncology, LLC Ronald Harris Grants/Research Support U.S. Oncology Research Kimberly Harrow Full-time/part-time Employee Xcovery Holding Company Anne-Renee Hartman Full-time/part-time Employee Myriad Genetics, Inc. Anne-Renee Hartman Stock Shareholder (directly Myriad Genetics, Inc. purchased) nooshin Hashemi Sadraei Grants/Research Support Merck Max Hasman Full-time/part-time Employee Roche Max Hasman Stock Shareholder (directly Roche purchased) jon Hayenga Full-time/part-time Employee VisionGate Lei He Full-time/part-time Employee AbbVie Lei He Stock Shareholder (directly AbbVie, may own stock purchased) Pei He Full-time/part-time Employee Genentech Pei He Other (explain): past employee of Amgen Pei He Stock Shareholder (directly , Amgen purchased) Pei He Stock Shareholder (directly Gilead, Roche purchased) Shuang He Full-time/part-time Employee Eli Lilly and Company Shuang He Stock Shareholder (directly Eli Lilly and Company purchased) Ying He Full-time/part-time Employee Roche Diagnostics Diane Healey Full-time/part-time Employee Bristol-Myers Squibb Diane Healey Stock Shareholder (directly Bristol-Myers Squibb, Pfizer purchased) Priti Hegde Full-time/part-time Employee Genentech Fiona Hegi-Johnson Grants/Research Support Cancer Australia Joost Hegmans Consultant Amphera bv Rebecca Heist Consultant Boehringer Ingelheim, Ariad Rebecca Heist Honoraria Ariad Pharmaceuticals Matthew Hellmann Consultant BMS, Genentech, Merck, AZ, Inovio, Neon, Axelion Matthew Hellmann Grants/Research Support BMS, Genentech Todd Hembrough Full-time/part-time Employee NantOmics

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Bart Hendriks Full-time/part-time Employee Merrimack Pharmaceuticals Bart Hendriks Stock Shareholder (directly Merrimack Pharmaceuticals (Stock purchased) Options) Roy Herbst Consultant AstraZeneca, Eli Lilly, Genentech/Roche, Merck, Pfizer, Diatech, Kolltan, BMS Roy Herbst Grants/Research Support Genentech, Merck Roy Herbst Other (explain): Scientific Advisory Board: Diatech, Kolltan, Diatech Roy Herbst Other (explain): Travel and accomodations from Merck & Co., Inc. Jennifer Hernandez Full-time/part-time Employee Resolution Biology Rohini K Hernandez Full-time/part-time Employee Amgen Rohini K Hernandez Stock Shareholder (directly Amgen purchased) Hadas Hershkovich Full-time/part-time Employee Novocure Hadas Hershkovich Full-time/part-time Employee Novocure Nadine Hertel Full-time/part-time Employee Bristol-Myers Squibb Felix JF Herth Grants/Research Support Roche Diagnostics John Heymach Consultant AstraZeneca, Boehringer Ingelheim, Exeliris, Genentech, GlaxoSmithKline, Guardant Health, Lilly, Novartis, Synta John Heymach Grants/Research Support AstraZeneca, Bayer, GlaxoSmithKline Jonathan Hicks Honoraria AstraZeneca, Boehringer Ingelheim Toyoaki Hida Grants/Research Support Abbvie, Astellas, AstraZeneca, Clovis, Taiho, Novartis, Bristol-Meyers Squibb, Chugai Pharmaceutical, Daiichi Sankyo, Dainippon Sumitomo Pharma, Eisai, Kyowa Hakko Kirin, Lilly, Merck Serono, Nippon Boehringer Ingelheim, Novartis, Ono Pharmaceutical, Taiho Pharmaceutical, Takeda Toyoaki Hida Honoraria AstraZeneca, Bristol Myers Squibb, Chugai Pharma, Clovis Oncology, Lilly, Nippon Boehringer Ingelheim, Novartis, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Masayuki Higuchi Full-time/part-time Employee Hitachi Chemical Co., Ltd. Frank Hilberg Full-time/part-time Employee Boehringer Ingelheim RCV Traci Hilton Full-time/part-time Employee UbiVac Madeleine Hipp Full-time/part-time Employee CureVac AG Fumihiko Hirai Grants/Research Support Novartis Pharma Fumihiko Hirai Honoraria Chugai Pharmaceutical, Ono Pharmaceutical, Taiho Pharmaceutical Tomonori Hirashima Grants/Research Support Chugai Pharmaceutical, Ono Pharmaceutical, Merck Serono, AstraZeneca, Eli Lilly, MSD Sandrine Hiret Consultant AstraZeneca Fred R. Hirsch Consultant AstraZeneca, Pfizer, Novartis, Genentech, Lilly, BMS, Amgen, Biothera, Syntha,

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Merck, HTG, Ventana, Myriad, Verastem, Siemens Fred R. Hirsch Grants/Research Support AZ, Genentech, BMS, Merck, Pfizer, Lilly, Ventana, HTG, Novartis, Imclone, Genentech, Amgen, Celgene Vera Hirsh Honoraria AstraZeneca, Boehringer Ingelheim, Roche, Pfizer, Merck, BMS Vera Hirsh Other (explain): AstraZeneca, Boehringer Ingelheim, Roche, Pfizer, Merck, BMS (Advisory board) James Ho Consultant Pfizer, Roche, AstraZeneca, BI, MSD Chung-Man James Ho Grants/Research Support AVEO, MSD, AstraZeneca, ARIAD, Roche Chung-Man James Ho Honoraria Pfizer, Roche, AstraZeneca, Bi, Eli Lilly, Chung-Man MSD James Ho Speakers Bureau Pfizer, Roche, AstraZeneca, BI, Eli Lilly, Chung-Man MSD Tien Hoang Full-time/part-time Employee Genentech Maximilian Hochmair Honoraria Pfizer, AstraZeneca, Novartis, Roche Rachel Hodge Full-time/part-time Employee AstraZeneca Marco Hofmann Full-time/part-time Employee Boehringer Ingelheim RCV Stefan Holdenrieder Grants/Research Support Roche Diagnostics Ariadna Holynskyj Full-time/part-time Employee Bayer HealthCare Pharmaceuticals Inc David Hong Grants/Research Support Daichi-Sanko, Eisai, Merck, Novartis, Pfizer, Genentech, Lilly, MIRNA, Mirati, Amgen Henoch Hong Full-time/part-time Employee CureVac AG Anne Hoorelbeke Full-time/part-time Employee Santelys Association Hidehito Horinouchi Honoraria Bristol Myers Squibb Leora Horn Consultant AbbVie, Eli Lilly, Merck, Roche/Genentech, Bayer, Boehringer Ingelheim Leora Horn Consultant Genentech, Merck (compensated); BMS, BI, Xcovery, Bayer (uncompensated) Leora Horn Grants/Research Support AstraZeneca Leora Horn Other (explain): Biodesix Leora Horn Other (explain): Non-compensated consulting work for BMS, BI, Xcovery, and Bayer John Hornberger Consultant Trovagene Anwar Hossain Full-time/part-time Employee Eli Lilly Anwar Hossain Stock Shareholder (directly Eli Lilly and Company purchased) Katsuyuki Hotta Grants/Research Support Merck, Chugai Pharmaceutical, and Eli Lilly Japan Katsuyuki Hotta Honoraria Astellas Pharma, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Chugai Pharma, Daiichi Sankyo, Kaken Pharmaceutical, Lilly, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Katsuyuki Hotta Speakers Bureau Merck, Chugai Pharmaceutical, AstraZeneca, Daiichi-Sankyo 29

Pharmaceutical, Boehringer-Ingelheim, Nihon Kayaku, Taiho Pharmaceutical, and Sanofi-Aventis, Lilly, MSD, Chugai Pharma Karen Howarth Full-time/part-time Employee Inivata Michael Howland Full-time/part-time Employee Genentech Rebecca Hozak Full-time/part-time Employee Eli Lilly and Company Rebecca Hozak Stock Shareholder (directly Eli Lilly and Company purchased) Chengjie Hu Full-time/part-time Employee Boehringer Ingelheim (China) Investment Co. Ltd Hong-Ming Hu Other (explain): UbiVac; Co-Founder, Chief Scientific Officer Sylvia Hu Full-time/part-time Employee Genentech, Inc. Ye Hua Full-time/part-time Employee Hutchison MediPharma Limited Ye Hua Full-time/part-time Employee Hutchison MediPharma Ltd Ye Hua Stock Shareholder (directly Hutchison MediPharma Ltd purchased) Chen-Yu Huang Grants/Research Support Cancer Australia Dennis Chin- Huang Full-time/part-time Employee Boehringer Ingelheim Taiwan Limited Lun Han-Yao Huang Full-time/part-time Employee Bristol-Myers Squibb Hui Huang Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. Hui Huang Stock Shareholder (directly ARIAD Pharmaceuticals, Inc. purchased) Joice Huang Consultant ARIAD Pharmaceuticals, Inc. Joice Huang Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. Min Huang Full-time/part-time Employee Merck & Co. INC. Xin Huang Full-time/part-time Employee AbbVie Xin Huang Stock Shareholder (directly AbbVie, may own stock purchased) Yifan Huang Full-time/part-time Employee AstraZeneca Zhongdong Huang Full-time/part-time Employee TP Therapeutics, Inc. Rudolf Huber Consultant BMS, Boehringer Ingelheim, Celgene, Clovis Oncology, Eli Lilly, Novartis, Roche Rudolf Huber Grants/Research Support Pierre Fabre Rudolf Huber Honoraria ARIAD Pharmaceuticals, Inc., AstraZeneca, BMS, Boehringer Ingelheim, Pfizer, Roche Dirk Huebner Full-time/part-time Employee Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Brett Hughes Consultant Boehringer Ingelheim Elisha Hughes Full-time/part-time Employee Myriad Genetics, Inc. Elisha Hughes Stock Shareholder (directly Myriad Genetics, Inc. purchased) Rina Hui Consultant Merck Sharp & Dohme, AstraZeneca Rina Hui Consultant Merck Sharp & Dohme, AstraZeneca

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Rina Hui Honoraria Merck Sharp & Dohme, AstraZeneca, Bristol-Myers Squibb Shane Huntsman Consultant AstraZeneca Phillipe Huot-Marchand Consultant MSD Phillipe Huot-Marchand Full-time/part-time Employee Mapi Group Hatim Husain Grants/Research Support Trovagene Hatim Husain Speakers Bureau Bristol Myers Squibb Zain Husain Grants/Research Support Merck & Co, Inc Mahrukh Huseni Full-time/part-time Employee Genentech, Inc. Yasuko Ichikawa Speakers Bureau AstraZeneca, Boehringer Ingelheim Japan, Inc., Chugai Pharmaceutical Co., Ltd., Shionogi & Co., Ltd. Sai-Hong Ignatius Ou Consultant Advisory board: ARIAD, Pfizer, Roche/Genentech, Astra Zeneca Sai-Hong Ignatius Ou Grants/Research Support ARIAD, Pfizer, Roche/Genentech, Daiichi Sankyo, Astra Zeneca, Clovis Nnamdi Ihuegbu Full-time/part-time Employee Guardant Health, Inc Norihiko Ikeda Grants/Research Support Eli Lilly, Astra Zeneca, Pfeizer, Thaiho Pharmaceutical, Chugai Pharmaceutical, Behringer Fumio Imamura Grants/Research Support AstraZeneca, AstraZeneca KK, Boehringer Ingelheim, Chugai Pharma, Eisai, Lilly, Merck Serono, Novartis, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Fumio Imamura Honoraria AstraZeneca, AstraZeneca KK, Boehringer Ingelheim, Chugai Pharma, Lilly, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Akira Inoue Other (explain): Lectures fees from AstraZeneca, Chugai, and Boehringer-Ingelheim. Raluca Ionescu-Ittu Consultant Genentech Roche Irmgard Irminger-Finger Consultant BARD1 Life Sciences Neill Iscoe Full-time/part-time Employee Eli Lilly Canada Inc. Yuichi Ishikawa Consultant Fujirebio Inc. Yuichi Ishikawa Grants/Research Support Daiichi Sankyo Co., Ltd. Yuichi Ishikawa Grants/Research Support Daiichi Sankyo Co., Ltd. Hiroshi Isobe Speakers Bureau AstraZeneca, Bristol-Myers Squibb, Kyowa Hakko Kirin, Chugai, Boehringer Ingelheim Shunichiro Iwasawa Speakers Bureau TAIHO PHARMACEUTICAL CO., LTD David Jablons Consultant Encore Clinical David Jablons Other (explain): Equity Position in Encore Clinical Wolfgang Jacob Full-time/part-time Employee Roche Wolfgang Jacob Stock Shareholder (directly Roche purchased) Dirk Jäger Consultant Roche, BMS, Bayer Mohammad Jahanzeb Consultant Bristol Myers Squibb

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Yolanda Jaimes Honoraria liquid genomics Ian James Full-time/part-time Employee Contracted consultant for Roche L James Full-time/part-time Employee Pfizer L James Stock Shareholder (directly Pfizer purchased) Pasi Jänne Consultant Acea Bioscience Pasi Jänne Consultant Ariad Pasi Jänne Consultant ARIAD Pharmaceuticals, Inc., AstraZeneca, Boehringher Ingelheim, Chugai, Ignyta, Loxo Oncology, Merrimack, Pfizer, Roche Pasi Jänne Consultant AstraZeneca, Boehringher Ingelheim, Pfizer/Roche, Ariad Pharmaceuticals, Merrimack Pharmaceuticals, Chugai Pharmaceuticals, Loxo Oncology, Ignyta Pasi Jänne Consultant AstraZeneca, Boehringher Ingelheim, Pfizer/Roche, Ariad Pharmaceuticals, Merrimack Pharmaceuticals, Chugai Pharmaceuticals, Loxo Oncology, Ignyta, Sysmex Pasi Jänne Grants/Research Support AstraZeneca, Astellas, PUMA Pasi Jänne Other (explain): Gatekeeper, Dana-Farber Cancer Institute Pasi Jänne Other (explain): LabCorp; myself; compensated. This is for post-marketing royalties from Dana Farber Cancer Institute owned intellectual property on EGFR mutations licensed to Lab Corp. Pasi Jänne Other (explain): Other – post marketing royalties from DFCI owned patent on EGFR mutations licensed to Lab Corp. Pasi Jänne Other (explain): post marketing royalties from DFCI owned patent on EGFR mutations licensed to Lab Corp Pasi Jänne Other (explain): Post-marketing royalties from Dana-Farber owned intellectual property on EGFR mutations licensed to Lab Corp Pasi Jänne Other (explain): Post-marketing royalties on DFCI-owned patent on EGFR mutations (LabCorp) Pasi Jänne Stock Shareholder (directly Gatekeeper Pharmaceuticals purchased) Jacek Jassem Other (explain): travel support from Roche Anupam Jena Consultant Precision Health Economics Anupam Jena Full-time/part-time Employee Precision Health Economics Anupam Jena Honoraria Pfizer, through Precision Health Economics Suzanne Jenkins Full-time/part-time Employee AstraZeneca Suzanne Jenkins Stock Shareholder (directly AstraZeneca purchased) Guy Jerusalem Consultant Amgen; Celgene; Novartis; Pfizer; Roche Guy Jerusalem Grants/Research Support MSD; Novartis; Roche Guy Jerusalem Honoraria Celgene; Novartis; Roche

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Guy Jerusalem Other (explain): Travel, Accommodations, Expenses - GlaxoSmithKline; Novartis; Roche James Jett Full-time/part-time Employee Oncimmune LLC Saheli Jha Full-time/part-time Employee EpicentRx, Inc Jiafu Ji Grants/Research Support Peking University Cancer Hospital & Institute Fang Jiang Full-time/part-time Employee AbbVie Fang Jiang Stock Shareholder (directly AbbVie, may own stock purchased) Shan Jiang Full-time/part-time Employee Bristol-Myers Squibb Zhi Jiang Grants/Research Support Novogene Bioinformatics Institute Xiaolong Jiao Grants/Research Support Amgen Fei Jie Full-time/part-time Employee Astellas Pharma Global Development von Pawel Joachim Consultant Novartis Thomas John Consultant BMS, Pfizer, AstraZeneca, Roche Thomas John Consultant BMS, Pfizer, AstraZeneca, Roche Thomas John Other (explain): Travel expenses for ASCO 2014, 2015: AstraZeneca, Roche Thomas John Speakers Bureau BMS, Merck, AstraZeneca William John Full-time/part-time Employee Eli Lilly and Company William John Stock Shareholder (directly Eli Lilly and Company purchased) Adrienne Johnson Full-time/part-time Employee Foundation Medicine Adrienne Johnson Stock Shareholder (directly Foundation Medicine purchased) Melissa Johnson Consultant Astellas, Otsuka Pharamceuticals, Genentech/Roche, Celgene, BI Melissa Johnson Speakers or Advisory Board OncoMed, BerGEnBio, Lilly, EMD Serono, Kadmon, Janssen, Mirati Therapeutics, Genmab, Pgizer, AstraZeneca, Genetech/Roche, Stemcentrix, Novartis, Checkpoint Therapeutics, Array BioPharma, Regeneron Melissa Johnson Supported/Contracted OncoMed, BerGEnBio, Lilly, EMD Serono, Research/Grant Kadmon, Janssen, Mirati Therapeutics, Genmab, Pgizer, AstraZeneca, Genetech/Roche, Stemcentrix, Novartis, Checkpoint Therapeutics, Array BioPharma, Regeneron Greg Jones Full-time/part-time Employee Inivata Joshua Jones Full-time/part-time Employee Myriad Genetics, Inc. Joshua Jones Stock Shareholder (directly Myriad Genetics, Inc. purchased) Leif Jørgensen Consultant Bristol-Myers Squibb Robert Jotte Honoraria Eli Lilly, BMS Robert Jotte Speakers Bureau Eli Lilly, BMS Óscar Juan Grants/Research Support ROCHE

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Rosalyn Juergens Consultant AstraZeneca Rosalyn Juergens Consultant AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Lilly, Merck Sharp & Dohme, Novartis, Pfizer Rosalyn Juergens Consultant Bristol-Myers Squibb, Lilly, Merck (MSD), Pfizer, Roche Rosalyn Juergens Grants/Research Support AstraZeneca/MedImmune, Bristol-Myers Squibb, Merck Sharp & Dohme, Novartis Rosalyn Juergens Honoraria Bayer, Bristol-Myers Squibb, Boehringer Ingelheim, BetaPharma, AstraZeneca, AstraZeneca/MedImmune, Roche Canada Helen Jung Full-time/part-time Employee Boehringer Ingelheim Hayoun Paul Jung Full-time/part-time Employee AbbVie Paul Jung Stock Shareholder (directly AbbVie, may own stock purchased) Peter Kabos Grants/Research Support Radius Carmen Kahatt Full-time/part-time Employee PharmaMar Carmen Kahatt Stock Shareholder (directly PharmaMar purchased) Gregory Kalemkerian Grants/Research Support GlaxoSmithKline, Merck, OncoMed, Pfizer, Takeda Karl-Josef Kallen Consultant CureVac AG Hisashige Kanbara Full-time/part-time Employee Hitachi Chemical Co., Ltd. Shintaro Kanda Grants/Research Support AstraZeneca Shintaro Kanda Grants/Research Support AstraZeneca, ONO, BMS Shintaro Kanda Grants/Research Support Bristol-Myers Squibb Shintaro Kanda Honoraria AstraZeneca, Chugai, ONO, BMS, Taiho Barry Kaplan Consultant Celgene, Seattle Genetics Barry Kaplan Full-time/part-time Employee New York Presbyterian Hospital Barry Kaplan Stock Shareholder (directly Exelixis (recently sold), Seattle Genetics purchased) Nagla Karim Grants/Research Support Pfizer Nagla Karim Speakers Bureau Pfizer, Astra-Zeneca, Celgene, BMS, Merck Chris Karlovich Full-time/part-time Employee Clovis Oncology Sudeep Karve Full-time/part-time Employee AstraZeneca Nobuyuki Katakami Grants/Research Support AstraZeneca Nobuyuki Katakami Grants/Research Support MSD, Astellas, Eisai, Ono Pharma, Amgen, Shionagi, Daiichi Sankyo, Chugai Pharma, Eli Lilly Pharma, Boehringer Ingelheim Pharma, Bristol-Meyers Squibb, Maruishi Pharma, Merck Serono Nobuyuki Katakami Speakers Bureau AstraZeneca, Eli Lilly, Pfizer, Boehringer Ingelheim, Ono Pharma, Taiho Pharma, Novartis Pharma K.K., Terufumi Kato Consultant NONE Terufumi Kato Financial support from NONE tobacco company(ies) 34

Terufumi Kato Full-time/part-time Employee Lilly (spouse) Terufumi Kato Grants/Research Support Abbvie, Astellas, AstraZeneca, Boehringer Ingelheim, BMS, Chugai, Daiichi Sankyo, Kyowa Hakko Kirin, Lilly, MSD, Ono, Parexel, Pfizer, Quintiles, Taiho, Takeda, Yakult Honsha Terufumi Kato Honoraria AstraZeneca, Boehringer Ingelheim, BMS, Chugai, Kyowa Hakko Kirin, Lilly, Ono, Pfizer, Roche, Taiho Terufumi Kato Other (explain): NONE Terufumi Kato Stock Shareholder (directly NONE purchased) Howard Kaufman Consultant ; Amgen; Merck; Merck Serono; Prometheus Howard Kaufman Grants/Research Support ristol-Myers Squibb/Medarex Howard Kaufman Honoraria Alkermes; Amgen; EMD Serono; Merck; Prometheus; Sanofi Pasteur Howard Kaufman Other (explain): Travel, Accommodations, Expenses - Alkermes; EMD Serono; Sanofi Howard Kaufman Speakers Bureau Merck Jun Kawashima Full-time/part-time Employee Gilead Sciences Jun Kawashima Stock Shareholder (directly Gilead Sciences purchased) Paul Keall Grants/Research Support Varian Medical Systems Paul Keall Grants/Research Support Varian Medical Systems Anne Keating Full-time/part-time Employee Astellas Anne Keating Full-time/part-time Employee Astellas Pharma Global Development Robert Keith Grants/Research Support Bristol-Myers-Squibb Robert Keith Other (explain): VisionGate Robert Keith Speakers Bureau Boehringer-Ingelheim Karen Kelly Consultant Ariad, AstraZeneca (DMC & Ad Brd), BMS, Boehringer Ingelheim, Clovis, Genentech (DMC & Ad Brd), Eli Lilly and Company Karen Kelly Grants/Research Support Abbvie (Inst); Celgene (Inst); EMD Serono (Inst); Genentech (Inst); Gilead Sciences (Inst); Lilly (Inst); Millennium (Inst); Novartis (Inst); Synta (Inst) Karen Kelly Grants/Research Support AbbVie, Celgene, EMD Serono, Genentech, Gilead, Eli Lilly and Company, Millennium, Novartis Karen Kelly Honoraria Bristol-Myers Squibb; Roche Karen Kelly Other (explain): AZ Data Monitoring Committee Karen Kelly Other (explain): Patents, Royalties, Other Intellectual Property - Author Royalties for UpToDate, an evidence based, peer reviewed information resource, available via the web, desktop, and PDA Karen Kelly Other (explain): Royalties Karen Kelly Other (explain): Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; Clovis 35

Oncology; Lilly; Roche; Synta Ronan Kelly Grants/Research Support AstraZeneca Ronan Kelly Grants/Research Support AstraZeneca Hirotsugu Kenmotsu Grants/Research Support AstraZeneca K.K., Boehringer Ingelheim Hirotsugu Kenmotsu Honoraria AstraZeneca K.K., Boehringer Ingelheim, Bristol-Myers Squibb Japan, Chugai Pharmaceutical Co., Ltd, Eli Lilly Japan K.K, Kyowa Hakko Kirin Co., Ltd., ONO PHARMACEUTICAL CO., LTD, Taiho Pharmaceutical Co., Ltd. Gerard Kennealey Full-time/part-time Employee Incyte Corporation Mark Kennedy Full-time/part-time Employee Foundation Medicine Izidor Kern Speakers Bureau MSD David Kerstein Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. David Kerstein Other (explain): ARIAD Pharmaceuticals, Inc. Sandeep Khandhar Consultant Medtronic Anchit Khanna Full-time/part-time Employee Pfizer Leila Khoja Full-time/part-time Employee Astra Zeneca Takashi Kijima Honoraria Chugai Pharmaceutical Co. Elaine Kilgour Full-time/part-time Employee AstraZeneca Elaine Kilgour Stock Shareholder (directly AstraZeneca purchased) Anthony Kim Honoraria Boehringer Ingelheim Dong-Wan Kim Consultant BMS, Il-Yang, Novartis, Pfizer Dong-Wan Kim Grants/Research Support BMS, Il-Yang, Novartis, Pfizer Dong-Wan Kim Honoraria BMS, Il-Yang, Novartis, Pfizer Edward Kim Consultant AstraZeneca Edward Kim Consultant Eli Lilly and Company, Celgene, AstraZeneca, Boehringer Ingelheim Eun Young Kim Grants/Research Support National Research Foundation of Korea Ho Jin Kim Grants/Research Support Genzyme, Merck Serono, and Kael- GemVax Ho Jin Kim Other (explain): He serves on a steering committee for MedImmune and serves as an editorial board member of Multiple Sclerosis Journal - Experimental, Translational and Clinical Ho Jin Kim Speakers Bureau Bayer Schering Pharma, Idec, Genzyme, Merck Serono, Novartis, MedImmune, and Teva-Handok Jong Kyun Kim Full-time/part-time Employee Yuhan Corporation Joo-Hang Kim Grants/Research Support SIT from Roche, Lilly, AZ, MSD Young Kim Grants/Research Support Chugai Pharma Young Kim Honoraria AstraZeneca Young Kim Honoraria Boehringer Ingelheim, Chugai Pharma, Lilly, Pfizer

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Hedy Kindler Consultant Merck Hedy Kindler Grants/Research Support Merck Jennifer King Other (explain): Advisory Committee (Travel Reiumbursement Only) - Guardant Health Eilon Kirson Full-time/part-time Employee Novocure Kazuma Kishi Grants/Research Support CHUGAI PHARMACEUTICAL CO., LTD., Eli Lilly Japan K.K., MSD K.K., ONO PHARMACEUTICAL CO., LTD., TAIHO PHARMACEUTICAL CO., LTD. Kazuma Kishi Speakers Bureau CHUGAI PHARMACEUTICAL CO., LTD. Katsuyuki Kiura Grants/Research Support Chugai, Astellas Pharma Inc., AstraZeneca K.K., Nippon Boehringer Ingelheim Katsuyuki Kiura Grants/Research Support Taiho Katsuyuki Kiura Honoraria Eli Lilly and Company Japan K.K., Chugai Pharmaceutical Co.,Ltd, Pfizer Japan Inc., Novartis Pharma K.K. Katsuyuki Kiura Honoraria Taiho K Klamerus Full-time/part-time Employee Pfizer K Klamerus Stock Shareholder (directly Pfizer purchased) Ute Klinkhardt Full-time/part-time Employee CureVac AG Peter Klint Full-time/part-time Employee Bristol-Myers Squibb Stephan Klinz Full-time/part-time Employee Merrimack Pharmaceuticals Stephan Klinz Stock Shareholder (directly Merrimack Pharmaceuticals (Stock purchased) Options) Houke Klomp Grants/Research Support Roche Netherlands Amy Ko Full-time/part-time Employee Celgene (full-time) Amy Ko Full-time/part-time Employee Celgene (full-time) Sven Koch Full-time/part-time Employee CureVac AG Marianna Koczywas Full-time/part-time Employee Genentech/Roche Marianna Koczywas Stock Shareholder (directly Roche purchased) Hartmut Koeppen Full-time/part-time Employee Roche Andreas Kogelnik Stock Shareholder (directly Open Medicine Institute purchased) Yoshinobu Koguchi Other (explain): AgonOx; Travel reimbursement Yoshinobu Koguchi Other (explain): Beckman Coulter; Travel reimbursement Jong Sung Koh Full-time/part-time Employee Genosco Yasuhiro Koh Grants/Research Support Boehringer Ingelheim, Daiichi Sankyo Yasuhiro Koh Honoraria Boehringer Ingelheim, RainDance Technologies Alexander Kohlmann Full-time/part-time Employee AstraZeneca Alexander Kohlmann Stock Shareholder (directly AstraZeneca purchased) Jens Kollmeier Consultant Boehringer-Ingelheim, BMS, Roche, Lilly, MSD, Cellgene

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Jens Kollmeier Other (explain): Advisory Board Lung cancer; MSD, Boehringer Ingelheim, Roche, BMS Jens Kollmeier Other (explain): Speaker; BMS, Lilly Oncology Kanji Komatsu Full-time/part-time Employee Astellas Masashi Kondo Grants/Research Support Boehringer Ingelheim Masashi Kondo Grants/Research Support Chugai Pharma, Lilly, Novartis, Pfizer Masashi Kondo Honoraria AstraZeneca, Boehringer Ingelheim, Chugai Pharma, Lilly, Pfizer Masashi Kondo Speakers Bureau AstraZeneca, Chugai Pharma, Lilly Kartik Konduri Consultant Boehringer Ingelheim (Advisory Board) Kartik Konduri Consultant Celgene Kartik Konduri Consultant DAVA Pharmaceuticals Kartik Konduri Other (explain): Boehringer Ingelheim (Advisory Board), DAVA Pharmaceuticals (Advisory Board) Shengchun Kong Full-time/part-time Employee Gilead Sciences Teresa Kong Sanchez Full-time/part-time Employee Bristol-Myers Squibb Teresa Kong Sanchez Stock Shareholder (directly Bristol-Myers Squibb purchased) Catharina Korse Grants/Research Support Roche Diagnostics Beata Korytowsky Full-time/part-time Employee BMS Beata Korytowsky Stock Shareholder (directly Bristol-Myers Squibb purchased) Smita Kothari Full-time/part-time Employee Merck & Co Gabor Kovács Consultant BMS, Berlin-Chemie/A.Menarini, Lilly Hungária, Pfizer, Behring CSL Gabor Kovács Honoraria BMS, Berlin-Chemie/A.Menarini, Lilly Hungária, Pfizer, Behring CSL Marcin Kowanetz Full-time/part-time Employee Genentech Marcin Kowanetz Stock Shareholder (directly Roche purchased) Thomas Krahn Full-time/part-time Employee Bayer AG Thomas Krahn Stock Shareholder (directly Bayer AG purchased) Nicole Krämer Full-time/part-time Employee External statistician on behalf of Boehringer Ingelheim Pharma GmbH & Co KG Biberach, Germany Johannes Kratz Consultant Encore Clinical Johannes Kratz Consultant Encore Clinical Norbert Kraut Full-time/part-time Employee Boehringer Ingelheim RCV Mark Kris Consultant Ariad, Roche/Genentech, Array BioPharma, AstraZeneca, Clovis Oncology, Daiichi Sankyo, Pfizer, Threshold Pharmaceuticals Mark Kris Grants/Research Support Genentech/Roche, PUMA (Grant support to institution only), Pfizer Cornelia Kropf-Sanchen Consultant Novartis Cornelia Kropf-Sanchen Honoraria Novartis

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Lee Krug Full-time/part-time Employee Bristol-Myers Squibb Arthur Kudla Full-time/part-time Employee Merrimack Pharmaceuticals Chantal Kuijpers Grants/Research Support Pfizer Chantal Kuijpers Grants/Research Support Roche Hideo Kunitoh Honoraria Taiho Takayasu Kurata Grants/Research Support AstraZeneca Takayasu Kurata Grants/Research Support AstraZeneca, Chugai Takayasu Kurata Honoraria AstraZeneca, Chugai, Boehringer Ingelheim, Eli Lilly, Pifzer Takayasu Kurata Speakers Bureau AstraZeneca, Chugai, Boehringer Ingelheim, Eli Lilly Japan Raffael Kurek Full-time/part-time Employee Eli Lilly and Company Hiroshi Kuriki Full-time/part-time Employee Chugai Pharma Hiroshi Kuriki Stock Shareholder (directly Chugai Pharma purchased) Jaroslaw Kuzdzal Other (explain): Co-owner of the Medycyna Praktyczna publishing company, involved in teachnig of medical professionals and publishing medical journal and books Catherine Lai Full-time/part-time Employee Genentech, Inc. Darius Lakdawalla Consultant Chief Strategy Officer at Precision Health Economics which provides consulting services to pharmaceutical companies producing cancer treatments. Sivuonthanh Lam Full-time/part-time Employee Genentech Sivuonthanh Lam Full-time/part-time Employee Genentech/Roche Sivuonthanh Lam Stock Shareholder (directly Roche purchased) David Landau Consultant VisionRT Philippe Landreau Full-time/part-time Employee Pierre Fabre Medicament Corey Langer Consultant Abbott, ARIAD Pharmaceuticals, Inc., AstraZeneca, Bayer/Onyx, BMS, Cancer Support Community, Celgene, Clarient, Clovis Oncology, Lilly/ImClone, Merck, Millennium, Roche/Genentech Corey Langer Consultant AstraZeneca, Genentech, Bristol-Myer Squibb, Merck Corey Langer Consultant Bristol-Myers Squibb (BMS), ImClone, Sanofi-Aventis, Pfizer, Lilly, Amgen, AstraZeneca, Novartis, Genentech/Roche, Bayer/Onyx, Abbott, Morphotek, Biodesix, Clarient, Caris Dx, Vertex, Synta, Celgene, Boehringer-Ingelheim, Merck, Clovis, , Celgene Corey Langer Grants/Research Support Advantagene, ARIAD Pharmaceuticals, Inc., Celgene, Clovis Oncology, GSK, Inovio, Merck, Roche/Genentech Corey Langer Honoraria BMS, Lilly/ImClone, Roche/Genentech Corey Langer Other (explain): Data Safety Monitoring Committee: Lilly, Amgen, Synta, Agennix, Peregrine, 39

AbbVie, Incyte, SWOG Corey Langer Speakers Bureau Lilly, Genentech, OSI, Imclone/Bristol- Myers Squibb (BMS) (all curtailed as of 12/10) Rupert Langer Consultant MSD Merck Sharp & Dohme AG, Roche Diagnostics (Schweiz) AG Rupert Langer Honoraria Roche Pharma (Schweiz) AG Rupert Langer Other (explain): Advisory Board BMS Richard Lanman Full-time/part-time Employee Guardant Health, Inc. With stock Ownership Richard Lanman Other (explain): Employee with stock ownership in Guardant Health, Inc. Richard Lanman Stock Shareholder (directly Guardant Health, Inc. purchased) Primo Lara Grants/Research Support Milennium, Genentech, Janssen, Heat Biologics, Tracon, Merck, Polaris, Oncogenex, Incyte, Sanofi Janessa Laskin Grants/Research Support Roche, Eli Lilly, Boehringer Ingelheim Janessa Laskin Honoraria BI, Eli Lilly, Astra Zeneca and Roche Janessa Laskin Honoraria Roche, AstraZeneca, Boehringer Ingelheim Geoffrey Laurent Consultant BARD1 Life Sciences Scott Laurie Honoraria Boehringer Ingelheim, Pfizer, UpToDate Scott Laurie Other (explain): Boehringer Ingelheim, Pfizer (Advisory board) David Lawrence Full-time/part-time Employee AstraZeneca Andrew Lawson Full-time/part-time Employee Inivata Fabienne Le Gac Full-time/part-time Employee Novartis Soline Leblanc Consultant Bristol-Myers Squibb Chee Khoon Lee Honoraria AstraZeneca Christine Lee Full-time/part-time Employee Guardant Health, Inc Dae Ho Lee Honoraria Astra Zeneca Korea Dae Ho Lee Honoraria AstraZeneca Korea, BMS Korea, Boeringer-Ingelheim Korea, MSD Korea, Mundi Korea, Ono Korea, Roche Korea and Samyang Biopharrm Dae Ho Lee Other (explain): Personal fees for consulting and/or lectures from AstraZeneca Korea, Boehringer Ingelheim Korea, Bristol-Meyer-Squibb Korea, MSD Korea, Novartis Korea, Pfizer Korea and Samyang Biopharm Helen Lee Full-time/part-time Employee Merrimack Pharmaceuticals Helen Lee Stock Shareholder (directly Merrimack Pharmaceuticals (Stock purchased) Options) In Yong Lee Full-time/part-time Employee Genosco Jaekyoo Lee Full-time/part-time Employee Genosco Jaesang Lee Full-time/part-time Employee Oscotec James Lee Grants/Research Support Merck

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K Adam Lee Speakers Bureau Intuitive Surgery Pablo Lee Full-time/part-time Employee Eli Lilly and Company Pablo Lee Full-time/part-time Employee Eli Lilly and Company Pablo Lee Stock Shareholder (directly Eli Lilly and Company purchased) Sylvia Lee Grants/Research Support Juno Therapeutics and SU2C/AACR/CRI Young-Sung Lee Full-time/part-time Employee Yuhan Corporation Michael Lees Full-time/part-time Employee Bristol-Myers Squibb Natasha Leighl Consultant AstraZeneca Natasha Leighl Grants/Research Support Novartis Natasha Leighl Honoraria Pfizer Natasha Leighl Other (explain): AstraZeneca Rumo Leistner Honoraria Astra Zeneca, Boehringer Ingelheim, Lilly, Roche Hervé Lemasson Full-time/part-time Employee Bristol-Myers Squibb Hervé Léna Consultant MSD Hervé Léna Grants/Research Support Roche Hervé Léna Honoraria Astra Zeneca Roche Lilly BMS Hervé Léna Honoraria Boehringer Ingelheim, Bristol Myers Squibb Hervé Léna Other (explain): Consulting or advisory role: Roche, Bristol Myers Squibb, AstraZeneca, Lilly Hervé Léna Other (explain): Travel, accommodation, expenses: Boehringer Ingelheim, Pierre Fabre Oncologie, Pfizer, Roche E Jane Leonard Full-time/part-time Employee Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Shannon Leonard Full-time/part-time Employee Merrimack Pharmaceuticals Shannon Leonard Stock Shareholder (directly Merrimack Pharmaceuticals (Stock purchased) Options) Brian Lestini Full-time/part-time Employee Bristol-Myers Squibb Brian Lestini Stock Shareholder (directly Bristol-Myers Squibb purchased) Vincent Leveque Full-time/part-time Employee Genentech Matteo Levisetti Full-time/part-time Employee Mirati Therapeutics Matteo Levisetti Full-time/part-time Employee Mirati Therapeutics Matteo Levisetti Full-time/part-time Employee Mirati Therapeutics Laurie Lévy-Bachelot Full-time/part-time Employee MSD Christine Lhomel Full-time/part-time Employee Roche Christine Lhomel Full-time/part-time Employee Roche Lei Li Grants/Research Support Novogene Bioinformatics Institute Rose Li Consultant Eli Lilly and Company Shuanglian Li Full-time/part-time Employee ARIAD Pharmaceuticals, Inc.

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Shuanglian Li Other (explain): ARIAD Pharmaceuticals, Inc. Siyu Li Full-time/part-time Employee Novartis Xuemei Li Full-time/part-time Employee BMS Xuemei Li Stock Shareholder (directly BMS purchased) Yali Li Full-time/part-time Employee Foundation Medicine Yishan Li Full-time/part-time Employee TP Therapeutics, Inc. Chris Liang Full-time/part-time Employee Xcovery Holding Company Jianming Liang Consultant VisionGate Jun Liang Grants/Research Support Simcere Astra Liepa Full-time/part-time Employee Eli Lilly and Company Astra Liepa Stock Shareholder (directly Eli Lilly and Company purchased) Rogerio Lilenbaum Consultant Boehringer Ingelheim Eric Lim Consultant Abbott Molecular, Glaxo Smith Kline, Medela Eric Lim Grant/Research Support Medela, ScreenCell, Clearbridge Biomedics Eric Lim Speaker's Bureau Roche, Lily Oncology, Pfizer, Boehringer Ingelheim, Medela Lee Lim Full-time/part-time Employee Resolution Biology Chen-Sheng Lin Full-time/part-time Employee Bristol-Myers Squibb Chen-Sheng Lin Grants/Research Support Bristol-Myers Squibb Chen-Sheng Lin Stock Shareholder (directly Bristol-Myers Squibb purchased) Dongmei Lin Grants/Research Support Peking University Cancer Hospital & Institute Jason Litten Full-time/part-time Employee Clovis Elizabeth Little Full-time/part-time Employee Roche Frank Liu Full-time/part-time Employee Merck & Co. INC Jingyi Liu Full-time/part-time Employee Eli Lilly and Company Jingyi Liu Stock Shareholder (directly Eli Lilly and Company purchased) Stephen Liu Consultant Genentech, Pfizer, Celgene, Ariad, Boehringer Ingelheim, Perthera Zhongjuan Liu Grants/Research Support Roche Diagnostics Mar Llorente Grants/Research Support ROCHE Jun Lo Full-time/part-time Employee Foundation Medicine Arsene Loembe Full-time/part-time Employee Boehringer Ingelheim Bienvenu Frank Lohr Consultant C-RAd Frank Lohr Grants/Research Support Elekta, IBA Frank Lohr Honoraria Elekta, IBA Delphine Loirat Honoraria MSD Billy W. Loo Grants/Research Support Varian Medical Systems; RaySearch Laboratories 42

Billy W. Loo Honoraria Varian Medical Systems Billy W. Loo Other (explain): Board Member, TibaRay Inc. Ariel Lopez-Chavez Full-time/part-time Employee Genentech Fernando Lopez-Rios Grants/Research Support Abbott Fernando Lopez-Rios Grants/Research Support Roche Diagnostics Jose Lopez-Vilarino Full-time/part-time Employee PharmaMar James Love Full-time/part-time Employee Boehringer Ingelheim Alexander Lovejoy Full-time/part-time Employee Roche Christine Lovly Consultant Ariad, Clovis, Genoptix, Novartis, Pfizer, Sequenom Christine Lovly Grants/Research Support Abbott Molecular, Astra-Zeneca, Novartis, Qiagen, Xcovery Christine Lovly Honoraria Abbott Molecular, Qiagen Haolan Lu Full-time/part-time Employee Bristol-Myers Squibb Haolan Lu Stock Shareholder (directly Bristol-Myers Squibb purchased) Shun Lu Grants/Research Support 2014YZDC10600 Shun Lu Grants/Research Support AstraZeneca Xin Lu Full-time/part-time Employee AbbVie Xin Lu Stock Shareholder (directly AbbVie, may own stock purchased) You Lu Consultant A&Z, Roche, Lilly, Pfizer You Lu Grants/Research Support A&Z Gregory Lubiniecki Full-time/part-time Employee Merck & Co., Inc. Merlin Luetke-Eversloh Full-time/part-time Employee Bayer AG Gary Lyman Grants/Research Support Amgen Gustavo Lyons Speaker's Bureau Pfizer Patrick Ma Grants/Research Support Bristol-Myers-Squibb Patrick Ma Grants/Research Support Loxo Oncology, Medimmune, OncoMed, PrECOG, XCovery Wendy Ma Full-time/part-time Employee Pfizer Inc Wendy Ma Stock Shareholder (directly Pfizer Inc purchased) Philipp Mack Consultant Apton Biosystems Philipp Mack Consultant MolecularMD Philipp Mack Grants/Research Support Astellas Philipp Mack Grants/Research Support Boehringer Ingelheim Philipp Mack Grants/Research Support Boehringer Ingelheim Philipp Mack Honoraria AstraZeneca, Guardant Health, Lilly Oncology, Novartis Mikidachi Madi Full-time/part-time Employee Inivata Russell Madison Full-time/part-time Employee Foundation Medicine Makoto Maemondo Grants/Research Support Boehringer ingelheim 43

Makoto Maemondo Speakers Bureau AstraZenca, Chugai, Boehringer ingelheim Amit Mahajan Consultant Medtronic Sabine Mai Other (explain): 3D Signatures Inc. Karen Makhuli Full-time/part-time Employee G1 Therapeutics Joan Malcom Full-time/part-time Employee Jackson Laboratories Isabelle Malet Full-time/part-time Employee Novartis Rajesh Malik Full-time/part-time Employee G1 Therapeutics Michael Mann Consultant Encore Clinical Michael Mann Other (explain): Equity Position in Encore Clinical Jack Mardekian Full-time/part-time Employee Pfizer Jack Mardekian Stock Shareholder (directly Pfizer purchased) Gabriella Mariani Full-time/part-time Employee AstraZeneca Koen Mariën Grants/Research Support HistoGeneX Marcelo Marotti Full-time/part-time Employee AstraZeneca Marcelo Marotti Stock Shareholder (directly AstraZeneca purchased) Angela Märten Full-time/part-time Employee Boehringer Ingelheim Claudio Martin Speakers Bureau BMS . BI Mona Martin Grants/Research Support Critical Path Institute María Martín Grants/Research Support ROCHE Alex Martinez Grants/Research Support Incyte Corporation J-F Martini Full-time/part-time Employee Pfizer J-F Martini Stock Shareholder (directly Pfizer purchased) Bartomeu Massuti Grants/Research Support ROCHE Elizabeth Masters Full-time/part-time Employee Pfizer Elizabeth Masters Stock Shareholder (directly Pfizer Inc purchased) Joanna Masters Full-time/part-time Employee Pfizer Inc Christina Matheny Full-time/part-time Employee Genentech, Inc. Sara Mathews Full-time/part-time Employee Merrimack Pharmaceuticals Deepan Mathur Full-time/part-time Employee Roche Diagnostics Burkhard Matthes Other (explain): Lecture fees from Astra Zeneca, Boehringer Ingelheim, Helixor, Lilly, Novartis and Roche Burkhard Matthes Other (explain): Reimbursement of travel expenses by AstraZeneca and Boehringer Ingelheim Julien Mazieres Consultant Roche, Novartis, Pfizer, BMS, MSD, Astra- Zeneca Julien Mazieres Grants/Research Support Roche; BMS Julien Mazieres Honoraria Roche, Lilly, Astra-Zeneca, Novartis, Pfizer, Boerhinger Julien Mazières Other (explain): Advisory board AstraZeneca 44

Kelly McCarrier Grants/Research Support Critical Path Institute Edward McClay Honoraria Bristol-Myers Squibb; Genentech Edward McClay Speakers Bureau Bristol-Myers Squibb; Genentech; Merck Leanne McCulloch Full-time/part-time Employee Puma Biotechnology Inc. Tracey McCulloch Full-time/part-time Employee Novartis Tracey McCulloch Other (explain): Stocks: Novartis Cheryl McDade Grants/Research Support Eli Lilly Jeffrey McDonald Stock Shareholder (directly Arena Pharmaceuticals purchased) Jane McElveen Full-time/part-time Employee Oncimmune Ltd Andrea McKee Consultant Covidian (Medtronic) Andrea McKee Speakers Bureau Covidian(Medtronic) Brady McKee Other (explain): Spouse received speaking and consultancy fees from Covidian (Medtronic) Mark McKee Full-time/part-time Employee AbbVie Mark McKee Stock Shareholder (directly AbbVie, may own stock purchased) Janice Mehnert Consultant Amgen Dompé Janice Mehnert Grants/Research Support Merck, Novartis, Sanofi, Amgen Ranee Mehra Consultant Bayer, BMS, Genentech, Innate Pharma, Novartis Ranee Mehra Full-time/part-time Employee GlaxoSmithKline (husband), Genentech Ranee Mehra Honoraria Mirati Ranee Mehra Stock Shareholder (directly GlaxoSmithKline purchased) Minesh Mehta Honoraria Novocure Tarek Mekhail Consultant Trovagene Tarek Mekhail Other (explain): Advisory board or board of directors: Novartis, Pfizer, Roche Tarek Mekhail Stock Shareholder (directly Celgene, Gilead purchased) Vlada Melnikova Full-time/part-time Employee Trovagene Melody Mendenhall Consultant Clovis Oncology Xuehong Meng Grants/Research Support Novogene Bioinformatics Institute Toshi Menju Grants/Research Support Affymetrix Daniel Merrick Grants/Research Support Bristol-Myers-Squib Krista Meyer Full-time/part-time Employee Biodesix Michael Meyer Full-time/part-time Employee VisionGate Matthew Meyerson Other (explain): Foundation Medicine Gu Mi Full-time/part-time Employee Eli Lilly and Company Gu Mi Stock Shareholder (directly Eli Lilly and Company purchased) Sebastian Michels Honoraria Pfizer, Novartis, Boehringer Ingelheim

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Anita Midha Full-time/part-time Employee AstraZeneca Vincent Miller Full-time/part-time Employee Foundation Medicine Inc., current paid position as Chief Medical Officer Vincent Miller Stock Shareholder (directly Foundation Medicine purchased) York Miller Other (explain): VisionGate Aurélie Millier Consultant MSD Paul Mitchell Consultant AstraZeneca, Roche, Boehringer- Ingelheim, BMS, MSD, Merck Serono Paul Mitchell Consultant BMS, ROCHE,ASTRAZENECA, MSD, BOEHRINGER INGELHEIM Paul Mitchell Grants/Research Support Merck Serono Paul Mitchell Honoraria Roche, Merck Paul Mitchell Other (explain): (travel grants): Roche Paul Mitchell Other (explain): ROCHE; BMS; ASTRAZENECA Tetsuya Mitsudomi Consultant AstraZeneca, Boehringer Ingelheim, Chugai, Novartis, Pfizer, Taiho, Ventana Medical Systems Tetsuya Mitsudomi Grants/Research Support Astra-Zeneca, Boehringer-Ingelheim, Chugai, and Taiho Tetsuya Mitsudomi Honoraria AstraZeneca, Chugai Pharma, Pfizer Tetsuya Mitsudomi Speakers Bureau Astra-Zeneca, Boehringer-Ingelheim, Chugai, Taiho, and Pfizer Simonetta Mocci Full-time/part-time Employee Genentech, Inc. Susan Mockus Full-time/part-time Employee Jackson Laboratories Tony Mok Consultant ACFA Biosciences Tony Mok Consultant AstraZeneca, Roche/Genentech, Pfizer, Eli Lilly, BI, Merck Serono, MSD, Janssen, Clovis Oncology, BioMarin, GSK, Novartis, SFJ Pharmaceutical, ACEA Biosciences, Inc., , Aveo & Biodesix, BMS, geneDecode Co., Ltd., OncoGenex Technologi Tony Mok Full-time/part-time Employee The Chinese University of Hong Kong (Nonprofit) Tony Mok Grants/Research Support AstraZeneca, Boehringer Ingelheim, Pfizer, Novartis, SFJ Pharmaceuticals, Roche, Merck Sharp & Dohme, Clovis Oncology, Bristol-Myers Squibb Tony Mok Honoraria AstraZeneca, Roche/Genentech, Pfizer, Eli Lilly, BI, Merck Serono, MSD, Janssen, Clovis Oncology, BioMarin, GSK, Novartis, SFJ Pharmaceutical, ACEA Biosciences, Inc., Vertex Pharmaceuticals, BMS, AVEO & Biodesix, Prime Oncology, Amgen, OncoGenex Pharmaceu Tony Mok Other (explain): AstraZeneca, Roche/Genentech, Pfizer, Eli Lilly, BI, Merck Serono, MSD, Janssen, Clovis Oncology, BioMarin, GSK, Novartis, SFJ Pharmaceutical, ACEA Biosciences, Inc., Vertex Pharmaceuticals, Aveo & Biodesix, BMS, geneDecode Co., Ltd., 46

OncoGenex Technologi, IASLC, Chinese Lung Cancer Research Foundation Ltd., Chinese Society of Clinical Oncology (CSCO), Hong Kong Cancer Therapy Society (HKCTS) (Board of Directors) Tony Mok Speakers Bureau AstraZeneca, Roche/Genentech, Pfizer, Eli Lilly, BI, MSD, Amgen, Janssen, Clovis Oncology, GSK, Novartis, BMS, PrIME Oncology Tony Mok Stock Shareholder (directly Sanomics Limited purchased) Rafael Molina Grants/Research Support Roche Diagnostics Olivier Molinier Consultant BMS, Roche, Boehringer Marcin Moniuszko Grants/Research Support Scientific grants from Berlin-Chemie Poland, Bristol-Myers-Squibb Poland; SM Mlekovita Isabelle Monnet Grants/Research Support Lilly, Roche Katherine Monti Consultant Consultant to Pfizer, on assignment from Rho Alessandro Morabito Honoraria Roche, AstraZeneca, Boehringher, Bayer, Pfizer Peter N. Morcos Stock Shareholder (directly Roche purchased) Jean- Morere Honoraria Roche François Jean- Morere Honoraria Roche François Rian Morgan Full-time/part-time Employee IncellDx Daniel Morgensztern Consultant BMS, Celgene, Heat Biologics, Genentech Daniel Morgensztern Consultant Genentech, Bristo Myers Squibb, Heat Biologics, Celgene Daniel Morgensztern Other (explain): Celgene (Advisory Board) Daniel Morgensztern Speakers Bureau Genentech, Boehringer-Ingelheim Maiko Morishita Full-time/part-time Employee Astellas Satoshi Morita Consultant Astellas Satoshi Morita Grants/Research Support Boehringer Ingelheim Satoshi Morita Honoraria Astellas Satoshi Morita Honoraria AstraZeneca, Chugai, Eli Lilly, Boehringer Ingelheim Satoshi Morita Honoraria Boehringer Ingelheim Francoise Mornex Honoraria IBA MERCK ROCHE LILLY Denis Moro-Sibilot Consultant Eli Lilly, Novartis, Pfizer, Amgen, Roche, Astra Zeneca, Boehringer Ingelheim, Eli Lilly, BMS, MSD Denis Moro-Sibilot Honoraria Roche, Pfizer, Novartis, Eli Lilly, Boehringer, BMS, MSD Denis Moro-Sibilot Other (explain): Advisory Board with the following companies: Eli Lilly, Novartis, Pfizer, Amgen, Roche, Astra Zeneca, Boehringer Ingelheim

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Deborah Morosini Full-time/part-time Employee Foundation Medicine Inc. Anne Morosky Full-time/part-time Employee Merck John Morris Speakers Bureau Ingram Boehlinger Phuong Morrow Full-time/part-time Employee Amgen Phuong Morrow Stock Shareholder (directly Amgen purchased) Nassim Morsli Full-time/part-time Employee Boehringer Ingelheim Stefanie Mortimer Full-time/part-time Employee Guardant Health, Inc Monica Motwani Full-time/part-time Employee AbbVie Monica Motwani Stock Shareholder (directly AbbVie, may own stock purchased) Benjamin Movsas Grants/Research Support Philips Benjamin Movsas Grants/Research Support Varian Martha Mueller Full-time/part-time Employee Boehringer Ingelheim Leena Mukherjee Honoraria Pfizer Clive Mulatero Consultant Amgen, AstraZeneca, Boehringer Ingelheim, Bristol Meyers Squibb, Clovis, Ernst and Young, GE Healthcare, Glaxo Smith Klein, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Pierre Fabre, PRMA Consulting Clive Mulatero Grants/Research Support Boehringer Ingelheim, Roche Clive Mulatero Honoraria Boehringer Ingelheim, Bristol Meyers Squibb, Merck Sharp & Dohme, Pierre Fabre, Roche Clive Mulatero Other (explain): Boehringer Ingelheim, Bristol Meyers Squibb, Glaxo Smith Klein, Lilly, Novartis, Pfizer, Roche Thomas Muley Grants/Research Support Roche Diagnostics Thomas Muley Honoraria Roche Thomas Muley Other (explain): Travel funding, Roche Diagnostics Jiefen Munley Full-time/part-time Employee AstraZeneca Haruyasu Murakami Honoraria Astellas Pharma, AstraZeneca K.K., Boehringer Ingelheim, Bristol-Myers Squibb Japan, CHUGAI PHARMACEUTICAL CO., LTD., Lilly Japan, Novartis Pharma K.K., Ono Pharmaceutical Co., Ltd., Pfizer Inc., Taiho Pharmaceutical Co., Ltd. Tosei Murase Full-time/part-time Employee Astellas Pharma Inc. Andrea Murray Full-time/part-time Employee Oncimmune Ltd Patrick Murray Speakers Bureau Elekta Esther Musgrave-Brown Full-time/part-time Employee Inivata James Myerson Speakers Bureau Astra Zeneca Ernest Nadal Consultant Eli Lilly and Company, Boehringer, Astra Zeneca Masayuki Nagahashi Grants/Research Support DENKA

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Seema Nagpal Consultant Berg Seema Nagpal Other (explain): Novocure/ad board Seema Nagpal Other (explain): regeneron/ad board Rebecca Nagy Full-time/part-time Employee Guardant Health Rebecca Nagy Full-time/part-time Employee Guardant Health, Inc Tateaki Naito Honoraria Ono Pharamaceutical Co., Ltd. Kazuhiko Nakagawa Consultant Astellas Pharma Inc. Kazuhiko Nakagawa Grants/Research Support Chugai Pharma Kazuhiko Nakagawa Grants/Research Support Chugai Pharmaceutical Co.,Ltd./ Nippon Boehringer Ingelheim Co.,Ltd./Eli Lilly and Company Japan K.K, Daiichi Sankyo Co. Ltd. Kazuhiko Nakagawa Grants/Research Support MSD K.K., Chugai Pharmaceutical Co. Ltd., Ono Pharmaceutical Co. Ltd., Takeda Pharmaceutical Co. Ltd., Eisai Co. Ltd., Daiichi Sankyo Co. Ltd., Nippon Boehringer Ingelheim Co. Ltd., EPS Associates Co., Ltd., Quintiles Inc., Japan Clinical Research Operati Kazuhiko Nakagawa Grants/Research Support Novartis, Pfizer Japan Inc. Kazuhiko Nakagawa Honoraria Astellas Pharma Inc., Novartis Pharma K.K., Boehringer Ingelheim, Chugai Pharma Kazuhiko Nakagawa Honoraria Chugai Pharmaceutical Co.,Ltd./ Nippon Boehringer Ingelheim Co.,Ltd./Eli Lilly and Company Japan K.K., Daiichi Sankyo Co. Ltd., Pfizer Japan Inc. Kazuhiko Nakagawa Other (explain): Donations/Contributions from Chugai Pharmaceutical Co. Ltd. and Bristol Myers Squibb Company. Kazuhiko Nakagawa Other (explain): Lecture fees from Eli Lilly Japan K.K., AstraZeneca K.K., Pfizer Japan Inc., Astellas Pharma Inc., Nippon Boehringer Ingelheim Co., Ltd. Kazuhiko Nakagawa Speakers Bureau Astellas Pharma Inc., Novartis Pharma K.K. Yoshiro Nakahara Speakers Bureau Eli Lilly Japan K.K., Nippon Boehringer Ingelheim Co ., Ltd., TAIHO PHARMACEUTICAL CO., LTD Kenji Nakamaru Full-time/part-time Employee Daiichi Sankyo Co., Ltd. Yoichi Nakanishi Honoraria Pfizer Yoichi Nakanishi Speakers Bureau ONO PHARMACEUTICAL CO., LTD. Kazuhisa Nakashima Honoraria Lilly, Japan, Mochida Pharamaceutical Co., Ltd., Taiho Pharamaceutical Co., Ltd. Su Youn Nam Full-time/part-time Employee Yuhan Corporation Shivani Nanda Full-time/part-time Employee Eli Lilly and Company Shigeki Nanjo Grants/Research Support AstraZeneca Ronald Natale Consultant Trovagene Louie Naumovski Full-time/part-time Employee AbbVie

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Louie Naumovski Stock Shareholder (directly AbbVie, may own stock purchased) Joel Neal Consultant ARIAD Pharmaceuticals, Inc., ARMO BioSciences, Boehringer Ingelheim, Caret, Clovis Oncology, Nektar Joel Neal Grants/Research Support ARIAD Pharmaceuticals, Inc., ArQule, Boehringer Ingelheim, Exelixis, Merck, Nektar, Novartis, Roche/Genentech Alan Nelson Full-time/part-time Employee VisionGate Alan Nelson Stock Shareholder (directly VisionGate purchased) Tavette Neskorik Full-time/part-time Employee Mirati Therapeutics Saskia Neuteboom Full-time/part-time Employee Mirati Therapeutics Aaron Newman Consultant Roche Tera Newman-Eerkes Full-time/part-time Employee Resolution Biology Kien Nguyen Full-time/part-time Employee Roche Andrew Nicholson Consultant Astra Zeneca, Eli Lilly, Boehringer Ingelheim, Novartis, Pfizer, Bristol Myers Squib, Roche, Merck Andrew Nicholson Speaker's Bureau Astra Zeneca, Eli Lilly Daniela Niepel Full-time/part-time Employee Amgen Daniela Niepel Stock Shareholder (directly Amgen purchased) Jorge Nieva Stock Shareholder (directly Epic Sciences purchased) Inko Nimmrich Full-time/part-time Employee Novartis Makoto Nishio Consultant Novartis,ONO Pharmaceutical, Chugai Pharmaceutical, Eli Lilly, TAIHO Pharmaceutical, Pfizer Makoto Nishio Grants/Research Support Novartis, ONO Pharmaceutical, Chugai Pharmaceutical, Bristol-Myers Squibb, TAIHO Pharmaceutical, Eli Lilly, Pfizer, Astellas, AstraZeneca Makoto Nishio Honoraria AstraZeneca, Bristol-Myers Squibb Japan, Chugai Pharma, Lilly Japan, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Yasuhiko Nishioka Grants/Research Support Taiho Pharmaceutical Co.,Ltd. Dongfeng Niu Grants/Research Support Peking University Cancer Hospital & Institute Johannes Noe Full-time/part-time Employee F. Hoffmann-La Roche Naoyuki Nogami Honoraria Taiho Lucia Nogova Honoraria Pfizer Hiroshi Nokihara Grants/Research Support Astellas Pharma, AstraZeneca, Boehringer Ingelheim, Chugai Pharma, Daiichi Sankyo, Eisai, Eli Lilly, GlaxoSmithKline, Merck Serono Hiroshi Nokihara Grants/Research Support Merck Serono, Pfizer, Taiho Pharmaceutical, Eisai, Chugai Pharma, Eli Lilly, Novartis, Ono Pharmaceutical, Pfizer, Quintiles, Yakult 50

Hiroshi Nokihara Honoraria AstraZeneca, Ono Pharmaceutical, Eli Lilly, Bristol-Myers Squibb, Chugai, Boehringer Ingelheim, Sanofi, Taiho Pharmaceutical Kaname Nosaki Grants/Research Support MSD Kaname Nosaki Honoraria AstraZeneca K.K., Chugai Pharmaceutical Co., Ltd., Eli Lilly Japan, Kyowa Hakko Kirin Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd, Ono Pharmaceutical Co. Ltd. Kaname Nosaki Speakers Bureau AstraZeneca K.K., Chugai Pharmaceutical Co., Ltd., Eli Lilly Japan K.K., Kyowa Hakko Kirin Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd., Ono Pharmaceutical Co. Ltd. Silvia Novello Consultant MSD, BMS, Novartis,Eli Lilly, AstraZeneca, Roche Silvia Novello Speakers Bureau Eli Lilly, AstraZeneca, Merck Sharp & Dohme Limited, Boehringer Ingelheim, Roche, Bristol-Myers Squibb James Novotny Jr. Full-time/part-time Employee BMS James Novotny Jr. Grants/Research Support BMS James Novotny Jr. Stock Shareholder (directly BMS, Merck purchased) Anna Nowak Consultant Aduro Biotech, Bayer Pharmaceuticals, Boehringer Ingelheim, Roche Pharmaceuticals, Sellas Life Anna Nowak Grants/Research Support Astra Zeneca Anna Nowak Other (explain): Roche Pharmaceuticals; Aduro Biotech; Sellas Life Pharmaceuticals; Bayer Pharmaceuticals; Boehringer Ingelheim Anna Nowak Other (explain): Trial Steering Committee Membership for Roche Pharmaceuticals; Aduro Biotech; Sellas Life Pharmaceuticals; Bayer Pharmaceuticals; Boehringer Ingelheim Coleman Obasaju Full-time/part-time Employee Eli Lilly and Company Coleman Obasaju Stock Shareholder (directly Eli Lilly and Company purchased) Mary O'Brien Consultant Merck Sharp & Dohme, Abbvie, Pierre- Frabre, Bristol-Myers Squibb, GlaxoSmithKline, Daichii, Celgene, Medimmune, MSD Pfizer, Pierre Fabre Ken O'Byrne Honoraria Pfizer, Roche, AZD, BI, BMS, MSD, Lilly Oncology, Novartis Ken O'Byrne Other (explain): Pfizer, Roche, AZD, BI, BMS, MSD, Lilly Oncology, Novartis (Advisory board) Ken O'Byrne Other (explain): Roche, AZD, BI, MSD (Travel/accommodation expenses) Ken O'Byrne Other (explain): US Pastent 13/601,703 entitled ‘Global Analysis of Serum microRNAs as Potential Biomarkers for Lung Adenocarcinoma’, Australian patent 2015905380 entitled ‘Nucelic Acid Oligomers and Uses Thereof Ken O'Byrne Speakers Bureau Pfizer, Roche, AZD, MSD, Lilly Oncology, BI

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Ken O'Byrne Stock Shareholder (directly CARP Pharmaceuticals, Bluesky purchased) Biosciences Justin Odegaard Full-time/part-time Employee Guardant Health, Inc Peter O'Dwyer Consultant Five Prime Therapeutics, Genentech Peter O'Dwyer Grants/Research Support BBI Healthcare, Bristol-Myers Squibb, Celgene, Genentech, GlaxoSmithKline, Mirati Therapeutics, Novartis, Pfizer Peter O'Dwyer Other (explain): Eli Lilly (expert testimony) Peter O'Dwyer Stock Shareholder (directly TetraLogic purchased) Se-Woong Oh Full-time/part-time Employee Yuhan Corporation Yuichiro Ohe Consultant AstraZeneca, Chugai, Lilly, ONO, Novartis Yuichiro Ohe Grants/Research Support AstraZeneca, Chugai, Lilly, ONO, BMS, Dainippon-Sumitomo, Pfizer, Taiho, Novartis, Merck Serono Yuichiro Ohe Honoraria AstraZeneca, Chugai, Lilly, ONO, BMS, Daiichi-Sankyo, Nipponkayaku, Boehringer Ingelheim, Pfizer, MSD, Taiho, Clovis, Sanofi Carol O'Hear Stock Shareholder (directly Genentech/Roche purchased) Morihito Okada Grants/Research Support Taiho Hiroaki Okamoto Grants/Research Support AstraZeneca K.K., Bristol-Myers Squibb Company, CHUGAI PHARMACEUTICAL CO., LTD., Eli Lilly Japan K.K., Merck Serono Co., Ltd., MSD K.K., ONO PHARMACEUTICAL CO., LTD., PAREXEL International Inc., Sumitomo Dainippon Pharma Co., Ltd., TAIHO PHARMACEUTICAL CO., LTD., Takeda Pharmaceutical Company Limited. Isamu Okamoto Honoraria Boehringer Ingelheim Carlos Oliveira Full-time/part-time Employee Biodesix Anthony Olszanski Consultant Takeda, Merck Anthony Olszanski Grants/Research Support Takeda, Immunocore, EMD-Serono, Amgen, Incyte, Synta, TC Biopharm, Kyowa, Eli Lilly, Mirati, Pfizer, Ignyta, Novartis Anthony Olszanski Honoraria Takeda, BMS, Jansen Wlodzimierz Olszewski Honoraria Abbott, Boehringer Ingelfeim, MSD Pfizer Ozzie Olyaie Full-time/part-time Employee AbbVie Ozzie Olyaie Stock Shareholder (directly AbbVie, may own stock purchased) Shota Omori Honoraria AstraZeneca K.K., Boehringer Ingelheim, Chugai Pharmaceutical Co., Ltd., Ono Pharmaceutical Co., Ltd., Taiho Pharmaceutical Daniel O'Neill Full-time/part-time Employee LAM Therapeutics, Celgene (full-time) Teng Ong Stock Shareholder (directly Celgene purchased) Akira Ono Grants/Research Support Takeda Pharamaceutical Co., Ltd. 52

Akira Ono Honoraria Chugai Pharamaceutical Co., Ltd., Taiho Pharamaceutical Co., Ltd. Bryan Oronsky Full-time/part-time Employee EpicentRx, Inc Gyula Ostoros Consultant Amgen Patrick Ott Consultant Amgen, BMS, Alexion Patrick Ott Grants/Research Support BMS, Merck, Armo Biosciences, AstraZeneca/Medimmune, Celldex Patrick Ott Honoraria Merck, Genentech, Alexion, Cytomx, Celldex Gregory Otterson Consultant Ariad, Boehringer Ingelheim, Genentech Gregory Otterson Grants/Research Support BBI Healthcare, BMS, Celgene, Pfizer, GSK, PUMA, Clovis, Boehringer Ingleheim, Medimmune, Novartis Sai-Hong Ou Consultant Pfizer, Genentech/Roche, Astra Zeneca, ARIAD, Boehringer Ingelheim, Novartis (Advisory Board) Sai-Hong Ou Grants/Research Support ARIAD, Pfizer, Roche/Genentech, Daiichi Sankyo, Astra Zeneca, Clovis Sai-Hong Ou Honoraria AstraZeneca, Pfizer, Roche, Boehringer Ingelheim, Novartis Sai-Hong Ou Other (explain): Advisory Board or Board of Directors: ARIAD, Pfizer, Roche/Genentech, AstraZeneca Tobias Overbeck Honoraria Astra Zeneca, Boehringer-Ingelheim, Lilly Pharma Taofeek Owonikoko Consultant Bayer, Celgene, Genentech/Roche, Novartis Taofeek Owonikoko Grants/Research Support Astellas Pharma, Bayer, Celgene Taofeek Owonikoko Grants/Research Support Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Taofeek Owonikoko Grants/Research Support Novartis Taofeek Owonikoko Other (explain): Advisory board: Medivation, AbbVie, Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Geoffrey Oxnard Consultant Ariad, AstraZeneca, Boehringer-Ingelheim, Genentech Geoffrey Oxnard Consultant AstraZeneca, Boehringer-Ingelheim, Genentech, Ariad, Inivata Geoffrey Oxnard Honoraria AstraZeneca, Boehringer-Ingelheim Nicolas Ozan Full-time/part-time Employee Bristol-Myers Squibb Sukhmani Padda Consultant Clovis Oncology Sukhmani Padda Other (explain): Advisory Board: Clovis Oncology Silvia Paddock Consultant Eli Lilly and Company Ray Page Speakers Bureau Biodesix Paul Paik Consultant EMD-Serono Georg Pall Consultant AstraZeneca, Pfizer, Roche, Boehringer Joann Palma Full-time/part-time Employee AbbVie

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Joann Palma Stock Shareholder (directly AbbVie, may own stock purchased) Yoram Palti Consultant Peer Bridge Health Yoram Palti Other (explain): Travel support: Echosense, Novocure Yoram Palti Stock Shareholder (directly Bennet Inc, Novelus Dx purchased) Jean Pan Full-time/part-time Employee Amgen Jean Pan Stock Shareholder (directly Amgen purchased) Vassiliki Papadimitrakopoulou Consultant Astra Zeneca, Ariad, Bristol Myers Squibb, Genentech, Biothera, Janssen, Clovis, Merck Vassiliki Papadimitrakopoulou Grants/Research Support Clovis, Astra Zeneca, Merck, Mauro Giulio Papotti Grant/Research Support Novartis Mauro Giulio Papotti Honoraria Boheringer, EliLilly, AstraZeneca, Roche, Pfizer Drew Pardoll Consultant Amgen, GSK, Medimmune/Astrazeneca, Merck, Pfizer, Potenza, DNatrix Drew Pardoll Other (explain): Contracted research from BMS, Potenza, and Compugen Drew Pardoll Other (explain): IP rights or patents with BMS, Medimmune/Astrazeneca, Potenza Drew Pardoll Stock Shareholder (directly Compugen, Aduro, Potenza, Tizona purchased) Monika Parisi Full-time/part-time Employee Celgene (full-time) Keunchil Park Consultant Ono, Roche Keunchil Park Grants/Research Support Astra Zeneca Keunchil Park Other (explain): Advisory Board: Astellas, AZ, BI, Clovis, Eli Lilly, Hanmi, KHK, ONO, Novartis Harvey Pass Consultant Astra Zeneca, Emerald Logic, BMS Harvey Pass Grant/Research Support NCI/NIH, NHLBI, CDC, DOD, Belluck and Fox, NYU Cancer Center, Patient Philanthropy, Genentech, SomaLogic, Genentech, Nanostring Harvey Pass Honoraria Astra Zeneca, IASLC, AATS Jyoti Patel Consultant BMS, Astra Zeneca Manali Patel Consultant Celgene Corporation Manish Patel Full-time/part-time Employee Celgene (full-time) Sabina Patel Full-time/part-time Employee AstraZeneca Sabina Patel Stock Shareholder (directly AstraZeneca purchased) Nuzhat Pathan Full-time/part-time Employee Pfizer Inc Nuzhat Pathan Stock Shareholder (directly Pfizer Inc purchased) Suhas Patil Full-time/part-time Employee Roche Amita Patnaik Grants/Research Support Merck Bruce Patterson Full-time/part-time Employee IncellDx Bruce Patterson Stock Shareholder (directly IncellDx 54

purchased) Christopher Paustian Full-time/part-time Employee UbiVac Nick Pavlakis Consultant Boehringer Ingelheim Nick Pavlakis Honoraria Boehringer Ingelheim Dean Pavlick Full-time/part-time Employee Foundation Medicine Dean Pavlick Stock Shareholder (directly Foundation Medicine purchased) Nancy Paz Full-time/part-time Employee Merrimack Pharmaceuticals Nancy Paz Stock Shareholder (directly Merrimack Pharmaceuticals (Stock purchased) Options) Luis Paz-Ares Honoraria Roche, Eli Lilly and Company, AstraZeneca, Bristol Meyers (BMS), Merck&Sharp(MSD), Amgem, Pfizer, Novartis, Boehringer Ingelheim Michael Peake Consultant Bristol Myers Squibb Michael Peake Honoraria Eli Lilly and Company, Roche Pharmaceuticals, Pierre Fabre Ltd Valeria Pegoraro Grants/Research Support Astellas, Astrazeneca, Bayer, DOC Generici, Grunenthal, Helsinn, Lundbeck, Merck Serono, Merck Sharp & Dohme, Novartis, and Recordati. Barbara Peil Full-time/part-time Employee Boehringer Ingelheim Nir Peled Consultant Pfizer, BI, Roche, AZ, MSD, BMS, Lilly, Novartis, and NovellusDx Nir Peled Honoraria AZ, BI, ROCHE, MSD, BMS, ELI LILLY, NOVARTIS, PFIZER Nir Peled Speakers Bureau Merck Sharp & Dohme Corey Pelletier Full-time/part-time Employee Celgene (full-time) James Pellissier Full-time/part-time Employee Merck and Co., Inc. Desi Peneva Consultant Employee at Precision Health Economics which provides consulting services to Bristol-Myers Squibb Stanford Peng Full-time/part-time Employee AbbVie Stemcentrx Nathan Pennell Grants/Research Support Celgene John Penrod Full-time/part-time Employee Bristol-Myers Squibb Sophie Peres Full-time/part-time Employee Santelys Association Roman Perez-Soler Consultant Genentech, Lilly, USA LLC Maurice Pérol Consultant Astra-Zeneca, Boehringer-Ingelheim, Clovis Oncology, Roche Maurice Pérol Honoraria Pfizer, Novartis and Astra-Zeneca Maurice Pérol Speakers Bureau Eli Lilly and Company, Merck Milos Pesek Consultant BMS Milos Pesek Honoraria Roche, BI, AZ, Pfizer Solange Peters Consultant Amgen, Roche, MSD, Lilly, Merck Serono, Pfizer, AstraZeneca, Amgen, Cellgene, BI, BMS, Novartis, Morphotek, Merrimack, Merck Serono, F. Hoffmann–La Roche, Ltd,

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Daiichi-Sankyo Solange Peters Honoraria Clovis and Tesaro See Phan Full-time/part-time Employee Genentech M Catherine Pietanza Consultant Abbvie, Bristol-Myers Squibb, Celgene, Clovis Oncology M Catherine Pietanza Full-time/part-time Employee Merck & Co., Bristol-Myers Squibb, Novartis, OncoMed, Stem CentRx M Catherine Pietanza Honoraria Abbvie, Bristol-Myers Squibb, Celgene, Clovis Oncology, Genentech, Novartis M Catherine Pietanza Speakers Bureau PER, Quintiles Sandeep Pingle Full-time/part-time Employee Trovagene Inc Zofia Piotrowska Consultant AstraZeneca, Boehringer Ingelheim, Clovis Oncology Bilal Piperdi Full-time/part-time Employee Merck Bilal Piperdi Stock Shareholder (directly Merck purchased) Tony Pircher Full-time/part-time Employee Biocept Robert Pirker Honoraria For Advisory Board form AstraZenenca; Boehringer Ingelheim; Eli Lilly; Merck Sharp Dohme; Pfizer; Roche; Synta Robert Pirker Speaker's Bureau AstraZenenca; Boehringer Ingelheim; Eli Lilly Irina Pivneva Consultant Genentech Roche Xavier Pivot Honoraria Roche Vincent Plagnol Full-time/part-time Employee Inivata David Planchard Consultant Astrazenaca, Boehringer Ingelheim; Novartis; Roche; BMS; Merck; Lilly; Pfizer, MSD David Planchard Honoraria Astrazenaca, Roche, Lilly, Pfizer, Boehringer, BMS, Merck, Novartis Katerina Politi Consultant NCCN regardng afatinib proposals Katerina Politi Consultant Novartis Katerina Politi Grants/Research Support Astra Zeneca, Roche, Gilead, Kolltan Katerina Politi Other (explain): Molecular MD/MSKCC Royalties Santiago Ponce Grants/Research Support Incyte Corporation Srinivasu Poondru Full-time/part-time Employee Astellas Pharma Sanjay Popat Consultant Boehringer Ingelheim Sanjay Popat Honoraria Eli Lilly Helmut Popper Consultant Advisary Boards of Roche, BMS, AstraZeneca, Eli Lilly Helmut Popper Grant/Research Support Unrestricted grants from Boehringer- Ingelheim, BMS Pieter Postmus Consultant Boehringer Ingelheim, Celgene, Clovis Oncology, Eli Lilly, Halozyme, Teva Danielle Potter Full-time/part-time Employee AstraZeneca Danielle Potter Stock Shareholder (directly AstraZeneca purchased)

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Christoph Pöttgen Speaker's Bureau Roche Pharma Diane Potvin Consultant Mirati Therapeutics Damien Pouessel Consultant Astellas Pharma, AstraZeneca, Lilly, MSD, Novartis, Roche, Sanofi Damien Pouessel Grants/Research Support Rohe, Amgen, MSD Oncology, Oncognex Damien Pouessel Honoraria Roche, Novartis, Sanofi, Astellas Pharma, Lilly, MSD Oncology, Astra-Zeneca Damien Pouessel Honoraria Sanofi, Astellas Pharma, Boehringer- Ingelheim, Janssen, Amgen John Powderly Consultant Bristol-Myers Squibb, TopAlliance BioSciences Incm Curis, AstraZeneca/MedImmune, Genentech/Roche, BioCytics Inc, Carolina BioOncology Institute, PLLC John Powderly Full-time/part-time Employee Carolina BioOncology Institute, PLLC, BioCytics, Inc John Powderly Grants/Research Support Bristol-Myers Squibb, Incyte, Macrogenics, Lilly/ImClone, EMD Serono, AstraZeneca/MedImmune, Genentech/Roche, John Powderly Other (explain): Patents/royalties BioCytics is developing intellectual property for cellular immunotherapy John Powderly Speakers Bureau Genentech/Roche, Dendreon, Merck, Bristol-Myers Squibb John Powderly Stock Shareholder (directly BioCytics, Lion , Juno purchased) Therapeutics, Bluebird Bio, Kite Pharma, ZIOPHARM Oncology, Carolina BioOncology Institute, PLLC, Steve Powell Grants/Research Support Merck Chris Presley Full-time/part-time Employee VisionGate Melissa Price Full-time/part-time Employee Heat Biologics, Taris Biomedical Michelle Pugh Full-time/part-time Employee Inivata Philippe Pultar Full-time/part-time Employee Novartis Philippe Pultar Stock Shareholder (directly Novartis purchased) Kun Qian Other (explain): Travel funding, Roche Diagnostics Shukui Qin Grants/Research Support Simcere Jiaheng Qiu Full-time/part-time Employee Genentech Jiaheng Qiu Stock Shareholder (directly Genentech purchased) Gabrielle Quiggle Full-time/part-time Employee ICON Clinical Research Luis Raez Grants/Research Support Caris SL Harry Raftopoulos Full-time/part-time Employee Merck Harry Raftopoulos Stock Shareholder (directly Merck purchased) Suresh Ramalingam Consultant Amgen, Abbvie, AstraZeneca, Bristol- Myers Squibb, Boehringer Ingelheim, Celgene, Merck, Lilly, Genentech Shakti Ramkissoon Full-time/part-time Employee Foundation Medicine 57

Shakti Ramkissoon Stock Shareholder (directly Foundation Medicine purchased) Rodryg Ramlau Consultant MSD, Roche, Eli Lilly, BI (Boehringer Ingelheim) Rodryg Ramlau Honoraria MSD, Roche, Eli Lilly, BI (Boehringer Ingelheim) Reshma Rangwala Full-time/part-time Employee Merck & Co., Inc. Mitch Raponi Full-time/part-time Employee Clovis Arliene Ravelo Full-time/part-time Employee Genentech Roche Arliene Ravelo Stock Shareholder (directly Roche Holdings purchased) Victoria Raymond Full-time/part-time Employee Trovagene Bruno Raynard Other (explain): No conflicts of interest in relation with the present study. However, other conflicts of interest : fresenius-kabi, nutricia health science, nestlé home care, baxter SAS, chugai Dan Raz Consultant Cireca Neal Ready Consultant AZ, BMS, Celgene, Heat Biologics, Merck Neal Ready Honoraria BMS, Celgene, Heat Biologics Neal Ready Other (explain): (travel, accomodations, expenses): AstraZeneca Neal Ready Other (explain): (travel, accomodations, expenses): AstraZeneca Martin Reck Consultant Hoffmann-La Roche, Lilly, Bristol-Myers Squibb, Merck Sharp & Dohme, AstraZeneca, Boehringer-Ingelheim, Pfizer, Novartis, Celgene Martin Reck Honoraria Hoffmann-La Roche, Lilly, Bristol-Myers Squibb, Merck Sharp & Dohme, AstraZeneca, Boehringer-Ingelheim, Pfizer, Novartis, Celgene Martin Reck Speakers Bureau Roche, Eli Lilly and Company, BMS, MSD, AZ, Pfizer, Boehringer-Ingelheim, Celgene Karen Reckamp Consultant ARIAD Pharmaceuticals, Inc. Karen Reckamp Consultant Trovagene Karen Reckamp Grants/Research Support ARIAD Pharmaceuticals, Inc., Clovis, Xcovery Holding Company Karen Reckamp Other (explain): Clinical trial funding to City of Hope Comprehensive Cancer Center from Gilead Honey Reddi Full-time/part-time Employee Jackson Laboratories Charles Redfern Grants/Research Support Sharp Healthcare (Inst) Amanda Redig Consultant Boehringer-Ingelheim, Medtronic Shawn Regis Consultant Covidian (Medtronic) Noemi Reguart Grants/Research Support Boheringer-Ingelheim William Reichmann Full-time/part-time Employee ARIAD Pharmaceuticals, Inc. William Reichmann Other (explain): ARIAD Pharmaceuticals, Inc. Niels Reinmuth Consultant Bristol-Myers Squibb, Hoffmann-La Roche, Lilly, Novartis, Boehringer-Ingelheim, 58

Otsuka, Amgen, Pfizer, MSD Jordi Remon Consultant OSE immunotherapeutics Hongcan Ren Full-time/part-time Employee Hutchison MediPharma Ltd Markus Reschke Full-time/part-time Employee Boehringer Ingelheim RCV Jonus Reyna Full-time/part-time Employee VisionGate Craig Reynolds Consultant AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Genetech Craig Reynolds Full-time/part-time Employee US Oncology Craig Reynolds Honoraria Lilly, BI, BMS, Genentech, AZ Craig Reynolds Other (explain): (travel, accomodations, expenses): Lilly, BI, BMS, Genentech, AZ Craig Reynolds Speakers Bureau AstraZeneca, Boehringer Ingelheim, Celgene, Genetech, BMS Craig Reynolds Stock Shareholder (directly Gilead, US Oncology purchased) Alena Reznichenko Full-time/part-time Employee Merck Sharp & Dohme (Australia) Gregory Riely Consultant Genentech, Novartis, Roche Gregory Riely Grants/Research Support Pfizer, ARIAD, GSK, Roche, Novartis (all to institution) James Rigas Consultant AstraZeneca David Rimm Consultant Astra Zeneca, Agendia, Bethyl Labs, Biocept, BMS, Cell Signaling Technology, Cernostics, ClearSight, FivePrime, Genoptix/Novartis, Metamark Genetics, Merck, OptraScan, Perkin Elmer, and Ultivue. David Rimm Grants/Research Support • Cepheid, Genoptix, Gilead Sciences, Pierre Fabre, Perkin Elmer and Nantomics David Rimm Honoraria Genentech/Roche, Cell Signaling Technology, and Ventana David Rimm Other (explain): Equity in Metamark Genetics David Rimm Stock Shareholder (directly Metamark Genetics purchased) Andreas Rimner Grants/Research Support Boehringer Ingelheim, Varian Medical Systems Achim Rittmeyer Consultant BMS, Boehing, Lilly, Roche Achim Rittmeyer Grants/Research Support AstraZeneca, BMS, Boehringer Ingelheim, Lilly, MSD, Pfizer, Roche Naiyer Rizvi Consultant AstraZeneca/MedImmune, Genentech/Roche, Novartis, Marck Sharp and Dohme, Bristol-Myers Squibb Naiyer Rizvi Grants/Research Support AZ, Bristol-Myers Squibb Naiyer Rizvi Honoraria Merck Sharp and Dohme, MSD, Amgen Naiyer Rizvi Other (explain): Leadership: Gritstone Oncology Naiyer Rizvi Stock Shareholder (directly Gritstone Oncology purchased) Naiyer Rizvi Stock Shareholder (directly Gritstone Oncology purchased) Patrick Roberts Full-time/part-time Employee G1 Therapeutics

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Andrew Robinson Honoraria Merck, Bristol-Myers Squibb, AstraZeneca Cliff Robinson Consultant Radiologica Cliff Robinson Grants/Research Support Varian Medical Systems Cliff Robinson Speakers Bureau Varian Medical Systems, ViewRay Cliff Robinson Stock Shareholder (directly Radiologica purchased) Julia Rockberg Consultant Bristol-Myers Squibb Joanna Roder Full-time/part-time Employee Biodesix Ryan Rodriguez Full-time/part-time Employee IncellDx Delvys Rodríguez-Abreu Consultant Merck Sharp & Dohme, Bristol-Myers Squibb, Roche Delvys Rodríguez-Abreu Honoraria Merck Sharp & Dohme, Bristol-Myers Squibb, Roche Evan Rogers Full-time/part-time Employee TP Therapeutics, Inc. Christian Rolfo Consultant Mylan Christian Rolfo Grants/Research Support Sanofi Christian Rolfo Other (explain): Steering Committee RealTime Medicie Christian Rolfo Speakers Bureau Novartis Nitzan Rosenfeld Full-time/part-time Employee Inivata Jeffrey Ross Full-time/part-time Employee Foundation Medicine Jeffrey Ross Stock Shareholder (directly Foundation Medicine purchased) Patrick Ross Grants/Research Support Pinnacle Biologics Kazimierz Roszkowski-Sliz Consultant Helix BioPharma Corp. Jonathan Rothberg Stock Shareholder (directly Butterfly Networks, LAM Therapeutics, purchased) Hyperfine Technologies, Quantum Si Technologies Sandra Rotteveel Full-time/part-time Employee Roche Katja Rüdell Full-time/part-time Employee AstraZeneca Charles Rudin Consultant AbbVie, Boehringer Ingelheim, Bristol- Myers Squibb, Celgene, Clovis, GlaxoSmithKlein, Merck, Medivation, Novartis, AVEO Charles Rudin Grants/Research Support BioMarin Tina Rupnik Consultant AstraZeneca Tina Rupnik Full-time/part-time Employee Phastar Prudence Russell Grants/Research Support Merck Sharp & Dohme (Australia) James Ryan Full-time/part-time Employee AstraZeneca Ales Ryska Consultant MSD, Pfizer, BMS, AstraZeneca, Roche, Novartis, Boehringer Ingelheim Ales Ryska Grant/Research Support AstraZeneca, Roche Alicia Sable-Hunt Consultant Fuji Rebio Diagnostics Hideo Saka Grants/Research Support AstraZeneca, Daiichi Sankyo, Ono Pharmaceutical, Eli Lilly Japan, Bayer Yakuhin, Taiho Pharmaceutical, MSD, 60

Linical, Bristol-Myers Squibb, Sanofi Paresh Salgaonkar Full-time/part-time Employee Genosco Mary Salvatore Speakers Bureau Genentech (Speakers Bureau, specifically for interstitial lung disease) Oumar Samassékou Full-time/part-time Employee 3D Signatures Inc. Belen San Antonio Full-time/part-time Employee Eli Lilly, Lilly España Rachel Sanborn Consultant Seattle Genetics, Peregrine Pharmaceuticals, Ariad Rachel Sanborn Grants/Research Support Incyte Corporation, Bristol-Myers Squibb, Medimmune Alfredo Sanchez-Hernandez Grants/Research Support ROCHE Martin Sandelin Honoraria Bristol-Myers Squibb Alan Sandler Consultant Genentech/Roche Alan Sandler Full-time/part-time Employee Genentech, Inc. Alan Sandler Honoraria Genentech/Roche Alan Sandler Other (explain): Provided compensated expert testimony for Genentech/Roche Alan Sandler Stock Shareholder (directly Genentech/Roche purchased) Jacob Sands Consultant Bayer, Medtronic Jacob Sands Speakers Bureau Trovagene Alexandra Sanford Full-time/part-time Employee Celgene (full-time) Alexandra Sanford Stock Shareholder (directly Celgene purchased) Eric Santoni-Rugiu Grants/Research Support Roche Armando Santoro Consultant Amgen, Celgene, Takeda, Novartis, Arqule Edgardo Santos Speakers Bureau Genentech, Lilly US Oncology, Celgene, Pfizer, AstraZeneca, Novartis, Boehringer- Ingelheim, Merck, Biocept, Biodesix, Biotheranostics, Caris SL, Guardant Health Sanatan Saraf Full-time/part-time Employee Merck Indrani Sarkar Full-time/part-time Employee Genentech, Inc. Nova Sarkar Full-time/part-time Employee Boehringer-Ingelheim Limited Seijiro Sato Grants/Research Support DENKA Miyako Satouchi Grants/Research Support Chugai Pharmaceutical, Eli Lily Japan, Taiho Pharmaceutical, Pfizer Pharmaceutical, AstraZeneca, Bristol Myers Squibb, Ono Pharmaceutical, MSD Miyako Satouchi Grants/Research Support Pfizer Japan, AstraZeneca, Bristol-Meyers Squibb, Ono Pharmaceutical, Novartis Pharmaceutical, MSD, Astellas Pharmaceutical, Chugai Pharmaceutical, Taiho Pharmaceutical, Eli Lilly Japan Miyako Satouchi Honoraria Chugai Pharmaceutical, Eli Lily Japan, Taiho Pharmaceutical, Pfizer Japan, AstraZeneca, Boehringer Ingerheim, Bristol Myers Squibb, Ono Pharmaceutical, Novartis Pharmaceutical

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Miyako Satouchi Honoraria Pfizer Japan, AstraZeneca, Bristol-Meyers Squibb, Ono Pharmaceutical, Novartis Pharmaceutical, Chugai Pharmaceutical, Taiho Pharmaceutical, Eli Lilly Japan, Boehringer Ingelheim Deric Savior Honoraria BMS, Celgene Deric Savior Other (explain): Advisory board: Lilly Giorgio Scagliotti Consultant Eli Lilly Giorgio Scagliotti Honoraria Eli Lilly, Astrazeneca, Roche, Pfizer and Clovis Oncology Matthew Schabath Consultant AstraZeneca Friedemann Schad Grants/Research Support Helixor Heilmittel GmbH, ABNOBA GmbH, Iscador AG Eric Schaefer Grants/Research Support Incyte Corporation Kurt Schalper Grants/Research Support Genoptix, Tesaro, Vasculox, Inc Andreas Scheel Consultant Novartis Birgit Scheel Full-time/part-time Employee CureVac AG Matthias Scheffler Consultant Novartis, Boehringer Ingelheim, BMS Michael Schenker Consultant Amgen Arnaud Scherpereel Grants/Research Support Roche, Lilly Arnaud Scherpereel Honoraria Bristol-Myers Squibb Thomas Schlange Full-time/part-time Employee Bayer AG Thomas Schlange Stock Shareholder (directly Bayer AG purchased) Peter Schmid Grants/Research Support AZ, Genentech/Roche, Oncogenex, Novartis, Astellas, Medivation (all to institution) Peter Schmid Grants/Research Support Roche, Genentech, AZ, Astellas, medivation, novartis, oncogenex Peter Schmid Honoraria AZ, Pfizer, Merck Peter Schmid Other (explain): Spouse Genentech/Roche consulting Taylor Schreiber Full-time/part-time Employee Heat Biologics, Pelican Therapeutics, Shattuck Labs Alexa Schrock Full-time/part-time Employee Foundation Medicine Alexa Schrock Stock Shareholder (directly Foundation Medicine purchased) Andreas Schröder Full-time/part-time Employee CureVac AG Martin Schuler Consultant AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG), Lilly, Novartis Martin Schuler Grant/Research Support Boehringer Ingelheim, Bristol-Myers Squibb, Novartis Martin Schuler Honoraria Alexion, Boehringer Ingelheim, Bristol- Myers Squibb, Celgene, Lilly, Novartis Katja Schulze Full-time/part-time Employee Genentech Lee Schwartzberg Consultant Bristol-Myers Squibb

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Lee Schwartzberg Speakers Bureau Genentech Jan Scicinski Full-time/part-time Employee EpicentRx, Inc David Sebag-Monterfiore Honoraria Oncology Forum Martin Sebastian Consultant Novartis, BMS, Roche, Eli Lilly and Company, Boehringer-Ingelheim, Pfizer, MSD, Astra-Zeneca, Celgene Martin Sebastian Honoraria Roche, Pfizer, Astra-Zeneca, Novartis, BMS, MSD, Celgene, Lilly, Boehringer Ingelheim Erin Seeley Full-time/part-time Employee Protea Biosciences, Inc. Vasudha Sehgal Full-time/part-time Employee AbbVie Vasudha Sehgal Stock Shareholder (directly AbbVie, may own stock purchased) Tanguy Seiwert Consultant Merck Tanguy Seiwert Grants/Research Support Merck Nobuhiko Seki Grants/Research Support Bristol-Myers Squibb Company, CHUGAI PHARMACEUTICAL CO., LTD., DAIICHI SANKYO COMPANY, LIMITED, Eli Lilly Japan K.K., Merck Serono Co., Ltd., Nippon Boehringer Ingelheim Co ., Ltd., ONO PHARMACEUTICAL CO., LTD., Pfizer Japan Inc., TAIHO PHARMACEUTICAL CO., LTD. Nobuhiko Seki Speakers Bureau AstraZeneca K.K., Bristol-Myers Squibb Company, CHUGAI PHARMACEUTICAL CO., LTD., DAIICHI SANKYO COMPANY, LIMITED, Eli Lilly Japan K.K., Nippon Boehringer Ingelheim Co ., Ltd., ONO PHARMACEUTICAL CO., LTD., TAIHO PHARMACEUTICAL CO., LTD. Paulina Selaru Full-time/part-time Employee Pfizer Inc Paulina Selaru Stock Shareholder (directly Pfizer Inc, Zoetis, EnteroMedics, Nxstage purchased) Medical GE, Colgate Palmolive, 3M Giovanni Selvaggi Full-time/part-time Employee BMS Giovanni Selvaggi Stock Shareholder (directly BMS purchased) Paramita Sen Full-time/part-time Employee Novartis Paramita Sen Other (explain): Stocks: Novartis Suresh Senan Consultant Lilly Oncology Suresh Senan Grants/Research Support Varian Medical Systems Suresh Senan Honoraria Varian Medical Systems Peggy Senico Full-time/part-time Employee Pfizer Inc Lecia Sequist Consultant Boehringer-Ingelheim (uncompensated), Clovis Oncology (uncompensated), Compensated: AstraZeneca, Ariad, Genentech, Merrimack (uncompensated), Novartis (uncompensated), Taiho (uncompensated) Lecia Sequist Grants/Research Support Novartis

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Lecia Sequist Other (explain): Uncompensated consulting from Clovis, Boehringer Ingelheim, Merrimack, Taiho, Novartis Monika Serke Consultant Novartis, Roche, Boehringer-Ingelheim, AstraZeneca, Lilly, MSD, BMS, Celgene, Hexal, Clovis Monika Serke Honoraria Novartis, Roche, Boehringer-Ingelheim, AstraZeneca, Lilly, MSD, BMS, Celgene, Hexal Danila Serpico Full-time/part-time Employee Bayer S.p.A. Takashi Seto Grants/Research Support Astellas Pharma Inc, AstraZeneca K.K., Chugai Pharmaceutical Co., Ltd., Eisai Co.,Ltd, Eli Lilly Japan K.K., Merck Serono Co.,Ltd, MSD, Nippon Boehringer Ingelheim Co.,Ltd., Novartis Pharma K.K., Pfizer Japan Inc., Verastem Inc, YakultHonsha Co.,Ltd Takashi Seto Honoraria AstraZeneca K.K., Chugai Pharmaceutical Co., Ltd., Daiichi Sankyo Co. Ltd., Eli Lilly Japan K.K., Kyowa Hakko Kirin Co., Ltd., Mochida Pharmaceutical Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd, Nippon Kayaku Co., Ltd., Ono Pharmaceutical Co. Ltd., Pf Alison Sexton Ward Consultant Employee at Precision Health Economics which provides consulting services to Bristol-Myers Squibb Lesley Seymour Grants/Research Support AstraZeneca (provided funding for this CCTG trial) Riyaz Shah Consultant Boehringer Ingelheim Riyaz Shah Honoraria Boehringer Ingelheim Javad Shahidi Full-time/part-time Employee Eli Lilly and Company David Shames Full-time/part-time Employee Genentech, Inc. Geetha Shankar Full-time/part-time Employee Genentech Daniel Shao Weng Tan Honoraria Novartis, Pfizer Daniel Shao Weng Tan Other (explain): Advisory Board: Novartis, Bayer, Boehringer Ingelheim, EISAI, Loxo Oncology, Celgene, Merrimack Pharmaceuticals, Pfizer Daniel Shao Weng Tan Other (explain): Corporate-sponsored research: Novartis, Bayer, GlaxoSmithKline, AstraZeneca Daniel Shao Weng Tan Other (explain): Expense reimbursements: Novartis and MERCK. Geoffrey Shapiro Consultant Pfizer, Lilly, G1 Therapeutics, Vertex Pharmaceuticals Geoffrey Shapiro Grants/Research Support Lilly Padmanee Sharma Consultant Bristol-Myers Squibb, Amgen, GlaxoSmithKline, and AstraZeneca Padmanee Sharma Consultant Bristol-Myers Squibb, GlaxoSmithKline, AstraZeneca, Amgen, Jounce, KitePharma, Evelo, Neon Padmanee Sharma Other (explain): Founder and advisor for Jounce Therapeutics, (patent licensed): Jounce, BMS, Merck, Member of the Parker 64

Institute for Cancer Immunotherapy at M.D. Anderson Cancer Center Sunil Sharma Grants/Research Support Novartis Sunil Sharma Honoraria Novartis Advisory Board Alice Shaw Consultant ARIAD Pharmaceuticals, Inc., Blueprint Medicines, Daiichi Sankyo, EMD Serono, Ignyta, Novartis, Pfizer, Roche/Genentech, Taiho, LOXO Alice Shaw Consultant Pfizer, Novartis, Genentech/Roche, Ariad, Blueprint, LOXO, KSQ, Ignyta, Taiho, Daiichi-Sankyo, EMD Serono Alice Shaw Grants/Research Support ARIAD Pharmaceuticals, Inc., AstraZeneca, Novartis, Pfizer, Roche/Genentech Alice Shaw Honoraria Novartis, Pfizer, Roche Alice Shaw Other (explain): Advisory board or board of directors: Pfizer, Novartis, Genentech/Roche, ARIAD, Blueprint, WXO, KSQ Emily Sheldon-Waniga Full-time/part-time Employee Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Yue Shentu Full-time/part-time Employee Merck & Co., Inc. Frances Shepard Other (explain): Prognostic and predictive gene signature for early stage NSCLC Frances Shepherd Consultant Lilly, AstraZeneca, GlaxoSmithKline, Boehringer Ingelheim, Recombio, Synta, Bristol-Myers Squibb, Roche Frances Shepherd Grants/Research Support Boehringer Ingelheim Frances Shepherd Honoraria Lilly, AstraZeneca, Bristol-Myers Squibb, Merck Serono, Roche/Genentech, Merck/Schering Plough, Boehringer Ingelheim Frances Shepherd Stock Shareholder (directly Lilly, AstraZeneca purchased) Sherry Shi Consultant Genentech Roche Tomoko Shibutani Full-time/part-time Employee Daiichi Sankyo Co., Ltd. Ryota Shiga Full-time/part-time Employee Daiichi Sankyo. Co., Ltd. Norah Shire Full-time/part-time Employee AstraZeneca Keith Shults Full-time/part-time Employee IncellDx Dale Shuster Full-time/part-time Employee Daiichi Sankyo Dale Shuster Stock Shareholder (directly Daiichi Sankyo purchased) Yu Shyr Consultant Roche, Janssen, Aduro, Novartis Alison Sibley Full-time/part-time Employee Myriad Genetic Laboratories, Inc. Alison Sibley Stock Shareholder (directly Myriad Genetic Laboratories, Inc. purchased) Christian Sieder Full-time/part-time Employee Novartis Jonathan Siegel Full-time/part-time Employee Bayer HealthCare Pharmaceuticals Inc Frangiscos Sifakis Full-time/part-time Employee AstraZeneca

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Frangiscos Sifakis Stock Shareholder (directly AstraZeneca purchased) Alan Sihoe Consultant Medela AG (Baar, Switzerland) Branimir Sikic Consultant Threshold, Immune Design Branimir Sikic Grants/Research Support Sanofi, CellDex, Forty Seven, Gilead, Genentech, Novartis George Simon Grants/Research Support Boeringer Ingelheim, Merck George Simon Honoraria Genentech, Eli Lilly, Arriad, Celgene George Simon Speakers Bureau Celgene Veena Singh Full-time/part-time Employee Biocept Patsy Skabla Consultant Pinnacle Biologics Sarah Smalley Full-time/part-time Employee Inivata Sarah Smalley Full-time/part-time Employee Inivata Egbert Smit Consultant Eli Lilly, MSD, Boehringer Ingelheim Paul Smith Full-time/part-time Employee AstraZeneca Paul Smith Stock Shareholder (directly AstraZeneca purchased) Patrik Sobocki Consultant Bristol-Myers Squibb Patrik Sobocki Grants/Research Support Bristol-Myers Squibb Mark Socinski Grants/Research Support Celgene, Clovis, Eli Lilly and Company, Genentech Mark Socinski Honoraria Celgene Mark Socinski Speakers Bureau Celgene, Genentech Flavio Solca Full-time/part-time Employee Boehringer-Ingelheim RCV GmbH & Co KG Caitlyn Solem Consultant Bristol-Myers Squibb Hatem Soliman Other (explain): Celgene (Advisory Board), Eli Lilly (Advisory Board) Benjamin Solomon Consultant Pfizer, Novartis, Roche, BMS, Merck, AstraZeneca, Eisai Scott Soltys Consultant Nektar Therapeutics Ho-Juhn Song Full-time/part-time Employee Genosco Tao Song Full-time/part-time Employee Spectrum Pharmaceuticals Ross Soo Honoraria Novartis Richie Soong Grants/Research Support Biorad, Promega, Research Instruments Jens Benn Sørensen Grants/Research Support Roche Jean-Charles Soria Consultant Astra-Zeneca Jean-Charles Soria Consultant Boehringer Ingelheim, Roche, Clovis Oncology, Eli Lilly, Novartis Jean-Charles Soria Grants/Research Support Boehringer Ingelheim Jean-Charles Soria Honoraria Boehringer Ingelheim, Roche, Novartis Jessica Sorrentino Full-time/part-time Employee G1 Therapeutics Arturo Soto-Matos Full-time/part-time Employee PharmaMar Arturo Soto-Matos Stock Shareholder (directly Pharmamar 66

purchased) Pierre Jean Souquet Consultant Lilly, Pfizer, Roche Pierre jean Souquet Honoraria AstraZeneca, Bristol-Myers Squibb, Roche Lior Soussan-Gutman Full-time/part-time Employee Teva Lior Soussan-Gutman Other (explain): Employee of Oncotest (subsidiary of Teva pharmaceuticals), the distributor of Guardant360 in Israel James Spicer Consultant Boehringer Ingelheim James Spicer Other (explain): AstraZeneca David Spigel Consultant Celgene, Genentech (uncompensated) David Spigel Grants/Research Support Celgene David Spigel Other (explain): (Travel, Accomodations, Expenses): Novartis, Genentech, Pfizer David Spigel Speakers Bureau Novartis (uncompensated) Alexander Spira Consultant ARIAD Pharmaceuticals, Inc., AstraZeneca, Clovis Oncology, Roche Alexander Spira Grants/Research Support Roche Alexander Spira Other (explain): Travel support from Halozyme Alexander Spira Speakers Bureau Roche Vanessa Spotlow Full-time/part-time Employee Jackson Laboratories Katie Stabler Full-time/part-time Employee G1 Therapeutics Rolf Stahel Consultant Astellas, Astra Zeneca, BMS, Boehringer Ingelheim, Clovis, Eli Lilly, Genentech, MSD, Pfizer and Roche Rolf Stahel Speaker's Bureau Astellas, Boehringer Ingelheim and MSD Uz Stammberger Full-time/part-time Employee Merck Nicola Steele Honoraria Pfizer Dara Stein Full-time/part-time Employee United BioSource Corporation David Steinhauer Full-time/part-time Employee VisionGate, Inc. Anne Steino Full-time/part-time Employee DelMar Pharmaceuticals, Inc. Martin Steins Consultant Bristol-Myers Squibb Martin Steins Honoraria Bristol-Myers Squibb Edward Stepanski Consultant BMS Edward Stepanski Other (explain): (travel, accomodations, expenses): BMS Philip Stephens Full-time/part-time Employee Foundation Medicine Philip Stephens Stock Shareholder (directly Foundation Medicine purchased) Claus Steppert Honoraria Astra Zeneca, Boehringer Ingelheim, Lilly, Roche Phil Stevens Full-time/part-time Employee Foundation Medicine Phil Stevens Stock Shareholder (directly Foundation Medicine purchased) Thomas Stinchcombe Consultant Boehringer Ingelheim, Celgene

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Martin Stockler Grants/Research Support Astra Zeneca Julie Stone Full-time/part-time Employee Merck & Co., Inc. Claudia Stosnach Full-time/part-time Employee CureVacAG Sholi Strauss Full-time/part-time Employee Novocure John Strickler Grants/Research Support AbbVie Gero Struebbe Full-time/part-time Employee Novartis Gero Struebbe Other (explain): Stocks: Novartis Jay Strum Full-time/part-time Employee G1 Therapeutics Weiguo Su Full-time/part-time Employee Hutchison MediPharma Ltd Shunichi Sugawara Honoraria AstraZeneca, Chugai, Nippon Boehringer Ingelheim Byung-Chul Suh Full-time/part-time Employee Genosco James Suh Full-time/part-time Employee Foundation Medicine James Suh Stock Shareholder (directly Foundation Medicine purchased) Jeffrey Sullivan Consultant PHE, my employer, provides consulting services for many healthcare companies Erik Sulman Consultant Merck Erik Sulman Grants/Research Support Abbvie, Novocure Erik Sulman Honoraria Merck James Sun Full-time/part-time Employee Foundation Medicine James Sun Stock Shareholder (directly Foundation Medicine purchased) Yan Sun Full-time/part-time Employee AbbVie Yan Sun Stock Shareholder (directly AbbVie, may own stock purchased) Uma Sundram Consultant IncellDx Daniel Sussman Full-time/part-time Employee VisionGate Santosh Sutradhar Full-time/part-time Employee Novartis Jenny Svärd Consultant Bristol-Myers Squibb Martin Svaton Grants/Research Support Roche, BI, AZ Scott Swanson Consultant Covidien, Ethicon Kostas Syrigos Honoraria BMS, NOVARTIS, ROCHE, BI Zsuzsanna Szalai Speakers Bureau Novartis, Berlin Chemie, Pfizer, Lilly, Chiesi Sergio Szyldergemajn Full-time/part-time Employee PharmaMar Sergio Szyldergemajn Stock Shareholder (directly PharmaMar purchased) Kaisa-Leena Taipale Full-time/part-time Employee Eli Lilly and Company Toshiaki Takahashi Grants/Research Support AstraZeneca K.K., Chugai Pharamaceutical Co., Ltd., Eli Lilly Japan K.K., MSD K.K, Ono Pharamaceutical Co., Ltd. Pfizer Japan Inc, Takeda Pharmaceutical Company., LTD Toshiaki Takahashi Honoraria AstraZeneca K.K., Boehringer Ingelheim,

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Chugai Pharamaceutical Co., Ltd., Eli Lilly, Japan, Ono Pharamaceutical Co., Ltd., Pfizer Japan, Inc Koichi Takayama Speakers Bureau ONO PHARMACEUTICAL CO., LTD. Kentaro Takeda Full-time/part-time Employee Astellas Mitsuhiro Takenoyama Grants/Research Support Bristol-Myers, Chugai Pharmaceutical, Eli Lilly, Nippon Boehringer Ingelheim, Novartis Pharma, Ono Pharmaceutical Mitsuhiro Takenoyama Honoraria AstraZeneca, Chugai Pharmaceutical, Eli Lilly, Kyowa Hakko Kirin, Ono Pharmaceutical, Taiho Pharmaceutical Yuichi Takiguchi Grants/Research Support Boehringer Ingelheim, Chugai Pharma, Eisai, Kyowa Hakko Kirin, Lilly, Merck Serono, Mochida Pharmaceutical Co. Ltd., Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical Yuichi Takiguchi Honoraria AstraZeneca, Boehringer Ingelheim, Chugai Pharma, Daiichi Sankyo, Eisai, Kyowa Hakko Kirin, Lilly, Merck Serono, Mitsubishi Tanabe Pharma, Mochida Pharmaceutical Co. Ltd., Nippon Kayaku, Pfizer, Taiho Pharmaceutical, Titan Medical AmirAli Talasaz Other (explain): Employee with stock ownership in Guardant Health, Inc. Tomohide Tamura Honoraria Boehringer Ingelheim, Bristol Myers Squibb, Chugai Pharma, Eisai, Lilly Japan, OncoTherapy Science, Inc., Ono Pharmaceutical, Taiho Pharmaceutical, Yakult Honsha Daniel Shao- Tan Grants/Research Support Novartis, GSK, AstraZeneca Weng Daniel Shao- Tan Honoraria Pfizer, Novartis, Boehringer Ingelheim Weng Eng Huat Tan Other (explain): Boerhinger Ingelheim (Advisory board) Fenlai Tan Full-time/part-time Employee Bettapharma Tomohiro Tanaka Full-time/part-time Employee Chugai Pharma Xiongwen Tang Full-time/part-time Employee Roche Yiyun Tang Full-time/part-time Employee Pfizer Inc Yiyun Tang Stock Shareholder (directly Pfizer Inc purchased) Kazuko Taniguchi Full-time/part-time Employee MSD KK Naoki Tashiro Full-time/part-time Employee AstraZeneca KK Vanessa Tassell Full-time/part-time Employee Mirati Therapeutics Matthew Taylor Consultant Eisai; Onyx; PDX Pharmacy Matthew Taylor Grants/Research Support AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Celldex (Inst); Eisai (Inst); Merck KGaA (Inst); Novartis (Inst) Matthew Taylor Honoraria Eisai Mustapha Tehfe Consultant AstraZeneca Alison Templeton Full-time/part-time Employee AstraZeneca

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Alison Templeton Stock Shareholder (directly AstraZeneca purchased) Antje Tessmer Consultant Chugai, Novartis, BMS, Boehringer Ingelheim Antje Tessmer Grants/Research Support PPD Germany Nick Thatcher Consultant Amgen Nick Thatcher Consultant Eli Lilly and Company Nick Thatcher Speakers Bureau ELi Lilly and Company Noah Theiss Full-time/part-time Employee Roche Diagnostics Michael Thomas Consultant Amgen, Eli Lilly and Company Michael Thomas Honoraria Novartis, AstraZeneca, Roche, Pfizer, MSD, BMS, Lilly, Boehringer-Ingelheim Michael Thomas Other (explain): AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Eli Lilly, MSD, Novartis, Roche (Advisory Board) Michael Thomas Speakers Bureau AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Eli Lilly, MSD, Novartis, Roche Rachel Thomas Honoraria Astra Zeneca, Phizer, Pierre Fabre, BMS, MSD, Boehringer Ingelhiem Steven Thomas Grants/Research Support Eli Lilly Marcello Tiseo Consultant AstraZeneca, BMS, Boehringer Ingelheim, Eli Lilly, Novartis, Otsuka, Pierre Fabre Marcello Tiseo Grants/Research Support ARIAD Pharmaceuticals, Inc. Marcello Tiseo Other (explain): Serves on advisory board of BMS during the conduct of the study Caroline Tissing-Tan Other (explain): Sirtex Technology Germany GmbH Angela Tod Honoraria Boehringer-Ingelheim Limited, Lilly Anne Claire Toffart Consultant Bristol Myers-Squibb Yosuke Togashi Speakers Bureau Boehringer-Ingelheim Alper Toker Full-time/part-time Employee Istanbul University, Istanbul Medical School Alper Toker Grant/Research Support Medtronic Covidien Alper Toker Stock Shareholder (directly Medtronic Covidien purchased) Sara Tolaney Grants/Research Support Lilly, Genentech, Pfizer, Exelixis, Novartis, Merck James Tonra Full-time/part-time Employee Kadmon Corporation Luca Toschi Honoraria AstraZeneca, Boehringer Ingelheim, Eli Lilly, pPharma Jeffrey Townsend Consultant Sanofi Pasteur and Merck Leonardo Trani Full-time/part-time Employee AstraZeneca Joseph Treat Full-time/part-time Employee Eli Lilly and Company Joseph Treat Stock Shareholder (directly Eli Lilly and Company purchased) Maarten Treur Consultant Bristol-Myers Squibb Nataliya Trunova Full-time/part-time Employee Celgene (full-time) Nataliya Trunova Stock Shareholder (directly Celgene 70

purchased) Rebekah Tsai Consultant Apton Biosystems Ming Tsao Other (explain): prognostic and predictive gene signature for early stage NSCLC Marina Tschaika Full-time/part-time Employee Bristol-Myers Squibb Marina Tschaika Stock Shareholder (directly Bristol-Myers Squibb purchased) Masahiro Tsuboi Grants/Research Support AstraZeneca KK Masahiro Tsuboi Honoraria AstraZeneca KK, Boehringer Ingelheim Japan KK, Chugai Pharmaceutical Co., Covidien J., Daiichi-Sankyo, Eli Lilly Japan, Johnson & Johnson J., Ono Pharmaceutical Co., Pfizer Japan, Taiho Masanori Tsuchida Grants/Research Support DENKA Maxim Tsypin Full-time/part-time Employee Biodesix David Turner Full-time/part-time Employee Merck & Co., Inc. Michelle Turner Speaker's Bureau Genenetech, Merck Tal Twito Other (explain): Employee of Oncotest (subsidiary of Teva pharmaceuticals), the distributor of Guardant360 in Israel Kin-Pong U Full-time/part-time Employee Bio-Cancer Treatment International LTD Kin-Pong U Full-time/part-time Employee Bio-Cancer Treatment International LTD Koichi Uegaki Full-time/part-time Employee Astellas Pharma Inc. Jane Ung Full-time/part-time Employee TP Therapeutics, Inc. Damien Urban Other (explain): BMS Patrick Urban Full-time/part-time Employee Novartis Noa Urman Full-time/part-time Employee Biosense Webster, Novocure Joshua Usher Honoraria Liquid Genomics Ahmad Utomo Full-time/part-time Employee Kalbe Farma Arschang Valipour Honoraria Olympus Eric Vallieres Consultant Spiration, Uptake Medical Matthijs Van Gool Grants/Research Support Roche Netherlands René Van Ommen Full-time/part-time Employee Pfizer Ari Vanderwalde Consultant Bristol-Myers Squibb, Vector Oncology, Caris Life Sciences; Honoraria: Dava Oncology Johan Vansteenkiste Consultant Astra Zeneca, BMS Boehringer MSD, Boehringer Ingelheim, Eli Lilly and Company, MSD Oncology, Novartis Johan Vansteenkiste Grants/Research Support Amgen AstraZeneca Rocio Varea Full-time/part-time Employee Eli Lilly and Company Rocio Varea Stock Shareholder (directly Eli Lilly and Company purchased) Marileila Varella-Garcia Grant/Research Support Abbott Molecular Marileila Varella-Garcia Other (explain): Co-inventor in a patent owned by University

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of Colorado to use EGFR genomic status for selecting patients for targeted therapies Jean-Claude Vedovato Full-time/part-time Employee Pierre Fabre Medicament Karen Velastegui Full-time/part-time Employee Mirati Therapeutics Vamsidhar Velcheti Consultant BMS, Genetech, Merck & Co. INC Victor Velculescu Other (explain): Founder of Personal Genome Diagnostics Victor Velculescu Other (explain): On the Scientific Advisory Board of Ignyta Victor Velculescu Stock Shareholder (directly Personal Genome Diagnostics purchased) Bharathi Vennapusa Full-time/part-time Employee Roche Bharathi Vennapusa Full-time/part-time Employee Roche Diagnostics Jo-Anne Vergilio Full-time/part-time Employee Foundation Medicine Jo-Anne Vergilio Stock Shareholder (directly Foundation Medicine purchased) Katharina Verleger Consultant Bristol-Myers Squibb Cecile Rose Vibat Full-time/part-time Employee trovagene Victoria Villaflor Grants/Research Support Celgene, Novartis (paid directly to the University of Chicago) Everett Vokes Consultant Amgen, Astra Zenca, Boehringer- Ingelheim, Celgene, Eli Lilly, Genentech, Merck, Synta, VentiRx Anja Von Heydebreck Full-time/part-time Employee Merck Serono Anja Von Heydebreck Stock Shareholder (directly Stock and Other Ownership Interests - purchased) Merck Serono Joachim Von Pawel Other (explain): Ad Boards: Daiichi, Clovis, Roche, Vertex, Novartis Ute Von Wangenheim Full-time/part-time Employee Boehringer Ingelheim Sarah Vowler Full-time/part-time Employee AstraZeneca Catherine Wadsworth Full-time/part-time Employee AstraZeneca Heather Wakelee Consultant ACEA, Genentech (uncompensated), Helsinn, Peregrine, Pfizer Heather Wakelee Grants/Research Support Astrazeneca/MedImmune, BMS, Celegene, Clovis Oncology, Eli-Lilly, Exelixis, Genentech/Roche, Gilead Heather Wakelee Grants/Research Support Lilly, Clovis, Exelixis, AstraZeneca/MedImmune, Genentech/Roche, BMS, Gilead, Novartis, Xcovery, Pfizer, Celgene, Pharmacyclics Heather Wakelee Other (explain): Genentech (uncompensated) Kazushige Wakuda Honoraria Boehringer Ingelheim, Ono Pharamaceutical Co., Ltd., Taiho Pharamaceutical Co., Ltd. Jill Walker Full-time/part-time Employee AstraZeneca Johan Wallin Full-time/part-time Employee Eli Lilly Sweden Johan Wallin Stock Shareholder (directly Eli Lilly Sweden purchased) Callee Walsh Full-time/part-time Employee Protea Biosciences, Inc. Annette Walter Full-time/part-time Employee Bayer AG 72

Sherry Wang Full-time/part-time Employee Pfizer Saiama Waqar Grants/Research Support Bristol-Myers Squibb, Celgene, Daiichi Sankyo, EMD Serono, Genentech/Roche, Incyte Corporation, Lilly, Newlink Genetics, Novartis, Pfizer, Puma Biotechnology, Spectrum Pharmaceuticals, Synermore Biologics, Vertex, Xcovery Satoshi Watanabe Honoraria AstraZeneca, Boehringer Ingelheim, Chugai Pharma, Ono Pharmaceutical, Pfizer David Waterhouse Consultant Bristol-Myers Squibb, Celgene, Eli Lilly David Waterhouse Grants/Research Support Celgene David Waterhouse Speakers Bureau BMS, Genentech, Lilly, Celgene Daniel Waterkamp Full-time/part-time Employee Roche/Genentech Daniel Waterkamp Stock Shareholder (directly Roche purchased) Neil Watkins Grants/Research Support Paranta Biosciences Contract Research Agreement 2016 Role: CIA Birgit Wehnl Full-time/part-time Employee Roche Diagnostics Uri Weinberg Full-time/part-time Employee Novocure Glen Weiss Consultant Viomics, Paradigm, NantWorks Glen Weiss Other (explain): Advisory/Consultant: Viomics, Paradigm, NantWorks Glen Weiss Other (explain): Research Funding from Paradigm Glen Weiss Speakers Bureau Merck, Novartis Jared Weiss Consultant Clovis, Eli Lilly, Biodesix, AZ, Genentech, Oncoplex Jared Weiss Grants/Research Support Celgene, Novartis, Astellas, Merck, AZ, Pfizer, Medimmune, NantWorks Jared Weiss Other (explain): Astellas (CME and company sponsored trials), Celgene (IIT support, company sponsored trial support, steering committee), DSMB for EMD Serono, EMD Serono (DSMB member), GlaxoSmithKline (IIT support), Medimmune (company sponsored trial support), Merck (company sponsored trial support, IIT support), Pfizer (ompany sponsored trial support) Martin Weisser Full-time/part-time Employee Roche Martin Weisser Stock Shareholder (directly Roche purchased) Frederik Wenz Honoraria Eli Lilly and Company Maria Werner-Wasik Grant/Research Support ELEKTA Oncology Howard West Consultant ARIAD Pharmaceuticals, Inc., Astellas, AstraZeneca, BMS, Boehringer Ingelheim, Celgene, Roche/Genentech, Merck, Novartis, Pfizer Howard West Other (explain): Advisory Board: Ariad, AstraZeneca, BMS, Celgene, Genentech/Roche, Guardant, Merck, Novartis, Trevagene Howard West Other (explain): Speaker for Ariad and Genentech/Roche 73

Howard West Speakers Bureau ARIAD Pharmaceuticals, Inc., Genentech/Roche, Lilly Virginie Westeel Honoraria Bristol-Myers Squibb Paul Wheatley-Price Consultant Merck, Lilly, Boehringer Ingelheim, AstraZeneca Paul Wheatley-Price Honoraria Astra Zeneca, Boehringer Ingelheim, Eli Lilly, Merck, Novartis Debbie Whitcomb Full-time/part-time Employee Astellas Pharma Global Development John White Honoraria Astra Zeneca Jeffrey Whitten Full-time/part-time Employee TP Therapeutics, Inc. Stefan Willems Grants/Research Support Pfizer, Roche Keith Wilner Full-time/part-time Employee Pfizer Inc Keith Wilner Stock Shareholder (directly Pfizer Inc purchased) Michele Wilson Grants/Research Support Eli Lilly Katherine Winfree Full-time/part-time Employee Eli Lilly Maria Winter Full-time/part-time Employee Pfizer Ignacio Wistuba Consultant Bristol-Myers Squibb, Celgene, Clovis Oncology, GE Healthcare, Genecentric, Genentech/Roche, GlaxoSmithKline, Lilly Ignacio Wistuba Grants/Research Support Bayer, Genentech, Jounce Therapeutics, Merck, Myriad Genetics, OncoPlex Diagnostics Ignacio Wistuba Speakers Bureau Boehringer Ingelheim, Medscape, Pfizer Jürgen Wolf Consultant Amgen, Boehringer-Ingelheim , AstraZeneca, Novartis, Roche, BMS, MSD, Clovis, Bayer Jürgen Wolf Grants/Research Support MSD, Novartis, Pfizer, Roche Jürgen Wolf Honoraria Amgen, Boehringer-Ingelheim, AstraZeneca, Novartis, Roche, BMS, MSD, Clovis, Bayer Katharina Wolff Full-time/part-time Employee Eli Lilly and Company Katharina Wolff Stock Shareholder (directly Eli Lilly and Company purchased) Ann-Marie Woodgate Full-time/part-time Employee Merck Sharp & Dohme (Australia) Sam Woodhouse Full-time/part-time Employee Inivata Antoinette Wozniak Consultant Ariad, Astra-Zeneca Antoinette Wozniak Grants/Research Support Boehringer-Ingelheim Antoinette Wozniak Honoraria Eli Lilly Yi Long Wu Honoraria AstraZeneca, Roche, Eli Lilly, Pfizer, Sanofi Dieter Wuerflein Honoraria Astra Zeneca, Boehringer Ingelheim, Lilly, Merck, Roche Fan Xia Full-time/part-time Employee Roche Yan Xin Full-time/part-time Employee Gilead Sciences Yan Xin Stock Shareholder (directly Gilead Sciences purchased) Ruifeng Xu Full-time/part-time Employee Merck & C.o INC. 74

Wanhong Xu Full-time/part-time Employee AACEA Pharmaceutical Research, Hangzhou, China, and ACEA Biosciences Inc. San Diego, USA Xiao Xu Full-time/part-time Employee ACEA Pharmaceutical Research, Hangzhou, China, and ACEA Biosciences Inc. San Diego, USA Kraig Yager Full-time/part-time Employee Myriad Genetic Laboratories, Inc. Kraig Yager Stock Shareholder (directly Myriad Genetic Laboratories, Inc. purchased) Satomi Yagi Full-time/part-time Employee Hitachi Chemical Co., Ltd. Noboru Yamamoto Grants/Research Support Astellas, AstraZeneca, BMS, Boehringer- Ingelheim, Chugai, Daiichi Sankyo Co., Ltd, Taiho, Esai, Quintiles, Novartis, Daiichi- Sankyo, Eisai, Eli Lilly Japan, Nippon Boehringer Ingelheim, Novartis, Pfizer, Quintiles Noboru Yamamoto Speakers Bureau AstraZeneca, Pfizer, Eli Lilly, Chugai, BMS, ONO Nobuyuki Yamamoto Consultant AstraZeneca Nobuyuki Yamamoto Consultant Chugai Pharmaceutical Co., Ltd., Boehringer Ingelheim, AstraZeneca, Eli Lilly, Pfizer, Ono Pharmaceutical, Taiho Pharmaceutical, Lilly Japan Nobuyuki Yamamoto Honoraria Chugai Pharmaceutical Co., Ltd., Boehringer Ingelheim, AstraZeneca, Eli Lilly, Pfizer, Kyowa Hakko Kirin, Lilly Japan, MSD, Nippon Boehringer Ingelheim, Ono Pharmaceutical, Pfizer, Taiho Pharmaceutical, Yakult Honsha Takeharu Yamanaka Honoraria Chugai, Taiho, Takeda James Chih- Yang Consultant AstraZeneca, Roche/Genentech, Hsin Boehringer Ingelheim, MSD, Merck Serono, Novartis, Pfizer, Clovis Oncology, Eli Lilly, Bayer, Celgene, Astellas, Innopharmax, Ono Pharmaceutical, and Chugai Pharmaceutical James Chih- Yang Grants/Research Support AstraZeneca Hsin James Chih- Yang Honoraria AstraZeneca, Roche/Genentech, Hsin Boehringer Ingelheim, MSD, Merck Serono, Novartis, Pfizer, Clovis Oncology, Eli Lilly, Bayer, Celgene, Astellas, Innopharmax, Ono Pharmaceutical, and Chugai Pharmaceutical James Chih- Yang Other (explain): Advisory Board: Boehringer Ingelheim, Eli Hsin Lilly, Bayer, Roche/Genentech/Chugai, Astellas, MSD, Merck Serono, Pfizer, Novartis, Clovis Oncology, Celgene, Merrimack, BMS and Ono Pharmaceutical James Chih- Yang Other (explain): Uncompensated Advisory board: Hsin AstraZeneca David Yankelevitz Other (explain): I am a named inventor on a number of patents and patent applications relating to the evaluation of diseases of the chest including measurement of nodules. Some of these, which are owned by Cornell 75

Research Foundation (CRF), are non- exclusively licensed to David Yankelevitz Stock Shareholder (directly Accumetra purchased) Seiji Yano Grants/Research Support AstraZeneca, Boehringer-Ingelheim, Chugai Seiji Yano Speakers Bureau Boehringer-Ingelheim, Chugai Timothy Yap Consultant Pfizer Timothy Yap Grants/Research Support AstraZeneca, Clearbridge Biomedics, Vertex Timothy Yap Other (explain): Travel expenses - BMS, Janssen-Cilag, MSD, Vertex Kazuhiro Yasufuku Consultant Olympus America Inc, Intuitive Surgical, Johnson and Johnson Kazuhiro Yasufuku Grant/Research Support Research and Educational Grant for CME from Olympus Coorporation Christina Yau Consultant NantOmics Jennifer Yearley Full-time/part-time Employee Merck Sharp & Dohme (MSD) Yang Yi Grants/Research Support 2014YZDC10600 Yeun Mi Yim Full-time/part-time Employee Genentech Roche Yeun Mi Yim Stock Shareholder (directly Roche Holdings purchased) Yusuke Yokouchi Full-time/part-time Employee Daiichi Sankyo Co., Ltd. Hiroshige Yoshioka Honoraria AstraZeneca, Boehringer Ingelheim, Chugai Pharma, Lilly, Pfizer, Taiho Lauren Young Full-time/part-time Employee Foundation Medicine Lauren Young Stock Shareholder (directly Foundation Medicine purchased) Steven Young Grants/Research Support Pfizer Tina Young Full-time/part-time Employee BMS Tina Young Stock Shareholder (directly BMS purchased) Chong-Jen Yu Honoraria ONO, BMS, Pfizer, Novartis Helena Yu Consultant AstraZeneca, Boehringer Ingelheim, Clovis Helena Yu Grants/Research Support Clovis, AstraZeneca, Pfizer, Astellas, Incyte, Lilly Yang Yu Grants/Research Support Novogene Bioinformatics Institute Liwei Yuan Full-time/part-time Employee Hutchison MediPharma Ltd Sergey Yurasov Full-time/part-time Employee Clovis Erin Zagadailov Stock Shareholder (directly Amerisource Bergen; Takeda purchased) Pharmaceutical Company Limited Gérard Zalcman Consultant Boehringer Ingelheim, Bristol-Myers Squibb, Lilly, Pfizer, Roche Xingxing Zang Grants/Research Support Pfizer Hany Zayed Full-time/part-time Employee AbbVie Stemcentrx Ali Zeaiter Full-time/part-time Employee F. Hoffmann-La Roche Ltd Ali Zeaiter Other (explain): Leadership role at F. Hoffmann-La Roche Ltd 76

Ali Zeaiter Stock Shareholder (directly F. Hoffmann-La Roche Ltd purchased) Dayong Zhai Full-time/part-time Employee TP Therapeutics, Inc. Li Zhang Consultant Roche, Boerhinger Ingelheim, AstraZeneca, Bristol-Myers Squibb Li Zhang Grants/Research Support AstraZeneca, Pfizer, Eli Lilly & Co, Bristol- Myers Squibb Li Zhang Honoraria Lilly, AZ, BI Li Zhang Other (explain): Advisory Board Member: Boehringer Ingelheim, AstraZeneca, Roche Ling Zhang Full-time/part-time Employee Daiichi Sankyo Ling Zhang Stock Shareholder (directly Daiichi Sankyo purchased) Wei Zhang Full-time/part-time Employee Eli Lilly and Company Xiaotong Zhang Grants/Research Support Roche Diagnostics Huiling Zhen Full-time/part-time Employee Incyte Corporation Xiuyi Zhi Grants/Research Support Roche Diagnostics Caicun Zhou Consultant Roche, Lilly, Boehringer Ingelheim, AstraZeneca, Merck, Pfizer Caicun Zhou Honoraria Ingelheim, AstraZeneca, Merck Caicun Zhou Other (explain): Lecture fee from AZ, Eli Lilly, Pfizer, Roche, Sanofi Caicun Zhou Speakers Bureau Lilly, Pfizer,AZ,BI,Roche Lixin Zhou Grants/Research Support Peking University Cancer Hospital & Institute Jin Zhu Full-time/part-time Employee Bristol-Myers Squibb Jin Zhu Grants/Research Support Bristol-Myers Squibb Jin Zhu Stock Shareholder (directly Bristol-Myers Squibb purchased) Christoph Zielinski Consultant Bristol Myers-Squibb, Imugene, Roche, Abbie, Baxalta Ryan Ziemiecki Grants/Research Support Eli Lilly Oliver Zill Full-time/part-time Employee Guardant Health, Inc Annamaria Zimmermann Full-time/part-time Employee Eli Lilly and Company Annamaria Zimmermann Stock Shareholder (directly Eli Lilly and Company purchased) Wei Zou Full-time/part-time Employee Genentech Wei Zou Grants/Research Support Genentech Javier Zulueta Full-time/part-time Employee VisionGate Javier Zulueta Stock Shareholder (directly VisionGate purchased) Jacqueline Zummo Full-time/part-time Employee Eli Lilly and Company Jacqueline Zummo Stock Shareholder (directly Eli Lilly and Company purchased) Yunxia Zuo Full-time/part-time Employee Roche

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