Molecular Genetics of Bacteria & Phages
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Susan Gottesman, Phd National Institutes of Health
Boston Bacterial Meeting 2017 Crystal structure of Hfq in a complex with sRNA, Keynote speaker: RNA binding interfaces highlighted. Modeled using PDB: 4V2S Susan Gottesman, PhD National Institutes of Health Generously sponsored by: 2017 Boston Bacterial Meeting - Schedule and Introduction Thursday June 15 12:00 pm Registration 12:45 pm Opening Remarks I: Bacterial communities Chair: Matthew Ramsey Stephanie High-throughput analysis of targeted mutant libraries reveals new 1:00 pm Shames Legionella pneumophila effector virulence phenotypes Microbial hitchhiking promotes dispersal and colonization of new niches 1:20 pm Tahoura Samad by staphylococci Interactions between species introduce spurious associations in 1:40 pm Rajita Menon microbiome studies: evidence from inflammatory bowel disease The upper respiratory tract commensal Dolosigranulum pigrum inhibits 2:00 pm Silvio Brugger Staphylococcus aureus 2:20 pm Coffee Break II: Morphogenesis Chair: Eddie Geisinger Determining how bacteria regulate their rate of growth at the single- 2:50 pm Yingjie Sun molecule and single-cell levels by super-resolution microscopy Metabolic control of cell morphogenesis: perturbed TCA cycle halts 3:10 pm Irnov Irnov peptidoglycan biosynthesis Membrane remodeling at the division septum by the bacterial actin 3:30 pm Joseph Conti homolog FtsA 3:50 pm Kristin Little A cell envelope stress response system keeps cells in shape 4:10 pm Poster Session I - Science Center (#1-32, 60-66) III: Treatment strategies Chair: Alex Kostic Sebastien 5:30 pm BRACE for resistance: -
NCI Budget Fact Book for Fiscal Year 2012
100 90 80 70 60 50 40 30 20 10 100 0 92 78 55 30 National Cancer Institute 01020304050607080 90 100 01020304050607080 90 100 01020304050607080 90 100 2012 Fact Book U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health The information set forth in this publication is compiled and amended annually by the budget and finance staff of the National Cancer Institute and is intended primarily for the use by members of the Institute and others involved in the administration and management of the National Cancer Program. It is available online at h ttp://www.cancer.gov. Questions regarding any of the information contained herein may be directed to the Office of Budget and Finance, National Cancer Institute, 9000 Rockville Pike, Bethesda, Maryland, 20892 TABLE OF CONTENTS Executive Summary Fiscal Year 2012 Annual Report .......................................................iii Organization Director's Biography ...................................................................... O-1 Former Directors of the NCI .......................................................... O-2 National Cancer Advisory Board ................................................... O-4 NCI-Frederick Advisory Committee .............................................. O-8 Clinical Trials and Translational Research Advisory Committee O-10 Boards of Scientific Counselors and Advisors ............................ O-14 President's Cancer Panel ........................................................... O-15 Scientific Program Leaders ........................................................ -
American Academy of Microbiology
American Academy of Microbiology Dynamic Issues in Scientific Integrity: Collaborative Research .. Dynamic Issues in Scientific Integrity: Collaborative Research a report from The American Academy of Microbiology Prepared by Francis L. Macrina COLLOQUIUM STEERING COMMITTEE Francis L. Macrina (Chair) Virginia Commonwealth University Susan Gottesman National Cancer Institute, National Institutes of Health Bernard P. Sagik Drexel University Keith R. Yamamoto University of California, San Francisco BOARD OF GOVERNORS, AMERICAN ACADEMY OF MICROBIOLOGY Rita R. Colwell (Chair) University of Maryland Biotechnolo~ Institute Harold S. Ginsberg National Institutes of Health Susan A. Henry Carnegie Mellon University Martha M. Howe University of Tennessee, Memphis Eugene W. Nester University of Washington Mary Jane Osbom University of Connecticut Health Center School of Medicine Melvin I. Simon California Institute of Technology 4 Preface , his report from the colloquium on “Dynamic Issues in Scientific Integrity: Collaborative Research” is published by the American Academy of T Microbiology which provides summary statements on timely and impor- tant issues for scientists, governmental agencies, industry, and the public. The Academy focuses on issues that have broad implications for society. This colloquium convened 12 individuals who have significant experience with the issues under consideration. The colloquium was supported by the National Science Foundation and the American Society for Microbiology. This white paper includes an in-depth analysis of the issues and recommenda- tions to individuals involved in teaching courses in scientific integrity, to the broad microbiology community, to policy makers who have concerns about collaborative scientific research, and to the lay public. Scientific societies, as well as academic institutions, have sponsored workshops and forums that have addressed the entire spectrum of issues in scientific integrity. -
March–April 2008 (PDF File)
. Fostering Communication and Coii. ah oration The nihCatalyst A Publication for NIH Intramural Sciintists National Institutes of Health bOffice of the Director b Volume 16, Issue 2b March-Aprii 2008 Bias Against Women in Science: The problem, policy, history, & fix It’s Still There, and It’s Got to Cleaning Up Cell-Line Go Cross-Contamination by Fran Pollner by Christopher Wanjek f only mouse cells had ears, whis- Women in Biome kers, and a tail. These would Practices for I make it much easier to identify Best the type of cross-contamination that Sustaining Career Success for decades has plagued laboratories, invalidated years of research, side- Careers tracked careers, and possibly squan- NIH Working Group on Women in Biomedical dered millions of research dollars. National Center for Research Resources In well-documented cases that Office of Research on Women’s Health highlight both the range and ubiq- uity of the situation, guinea pig cells March 4, 2008 have turned out to be mouse cells, ovarian cancer cells have been dis- guised as breast cancer cells, and, in extreme cases, some cell lines have been unidentifiable. Fran Pollner NIH is not immune, neither in the Agents of Change: Discussing NIH initiatives to correct gender imbalances are (left to research performed here nor in the right) Joan Goldberg, executive director, American Society for Cell Biology’: Jeremy Berg, NIGMS director; Joan Schwariz. assistant director, OIR; Valerie Florance, deputy directorfor products produced. Many cell lines extramural programs, NLNJ Walter Schaffer, senior scientific advisorfor extramural from reputable sources are acciden- research; Raynard Kington, NIH deputy director; and panel chair Kath>yn Zoon, director of tally mischaracterized or masquerad- intramural research, NIAID ing as another kind of cell unbe- knownst to the supplier or user. -
Making Genes, Making Waves: a Social Activist in Science
Making Genes, Making Waves Making Genes, Making Waves A SOCIAL ACTIVIST IN SCIENCE .......JON BECKWITH HARVARD UNIVERSITY PRESS CAMBRIDGE, MASSACHUSETTS AND LONDON, ENGLAND 2002 Copyright © 2002 by Jon Beckwith All rights reserved Printed in the United States of America Library of Congress Cataloging-in-Publication Data Beckwith, Jonathan R. Making genes, making waves : a social activist in science / Jon Beckwith. p. cm. Includes bibliographical references. ISBN 0-674-00928-2 (hardcover : alk. paper) 1. Beckwith, Jonathan R. 2. Geneticists—United States—Biography. 3. Political activists—United States—Biography. 4. Science—Social aspects. I. Title. QH429.2.B38 A3 2002 576.5Ј092—dc21 [B] 2002022747 Designed by Gwen Nefsky Frankfeldt ▲▲▲ Contents 1 The Quail Farmer and the Scientist 1 2 Becoming a Scientist 13 3 Becoming an Activist 38 4 On Which Side Are the Angels? 54 5 The Tarantella of the Living 68 6 Does Science Take a Back Seat to Politics? 83 7 Their Own Atomic History 98 8 The Myth of the Criminal Chromosome 116 9 It’s the Devil in Your DNA 135 10 I’m Not Very Scary Anymore 153 11 Story-Telling in Science 171 12 Geneticists and the Two Cultures 191 13 The Scientist and the Quail Farmer 211 Bibliography 219 Acknowledgments 227 Index 229 Making Genes, Making Waves CHAPTER ▲ 1 The Quail Farmer and the Scientist The stone farmhouse surrounded by fields of rapeseed and wheat is unassuming. Yet enveloped within it is the story of a dramatic life. It is 1998 and I have come to this isolated spot to renew an old friendship, perhaps to find out something about myself, and cer- tainly to explore a mystery.