A HISTORY of ENDOCRINOLOGY: the Fantastical World of Hormones
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ISSUE 115 SPRING 2015 ISSN 0965-1128 (PRINT) ISSN 2045-6808 (ONLINE) THE MAGAZINE OF THE SOCIETY FOR ENDOCRINOLOGY A HISTORY OF ENDOCRINOLOGY: the fantastical world of THE JOURNEY TO MODERN hormones ENDOCRINOLOGY PAGES 6–24 Placenta as parasite PHIL LOWRY’S NOVEL PEPTIDE HYPOTHESIS BEHIND THE SCIENCE OF MORNING SICKNESS P26 Make the most of training THE NEW REGISTRAR’S SURVIVAL GUIDE, AND BENEFITS OF REGIONAL NETWORKS P32–33 YOUR CHANCE TO GET NEW! GET READY FOR INVOLVED EQUIPMENT GRANTS EDINBURGH Future Committee members Up to £10,000 support from Your SfE BES 2015 deadline apply within the Society dates P3 P29 P30 www.endocrinology.org/endocrinologist WELCOME Editor: Dr Miles Levy (Leicester) Associate Editor: Dr Tony Coll (Cambridge) A WORD FROM Editorial Board: Dr Rosemary Bland THE EDITOR… Dr Dominic Cavlan (London) Dr Paul Foster (Birmingham) Dr Paul Grant (London) Managing Editor: Dr Jennie Evans Sub-editor: Caroline Brewser Design: Corbicula Design Society for Endocrinology 22 Apex Court, Woodlands, Welcome to this ‘History of Endocrinology’ themed edition, which has come together wonderfully Bradley Stoke, Bristol BS32 4JT, UK well. We start with an introduction to the fantastical world of hormones, and then take a journey Tel: 01454 642200 through the modern history of pituitary surgery. Following this, we learn about key discoveries Email: [email protected] Web: www.endocrinology.org in parathyroid, adrenal, thyroid and oestrogen- and testosterone-related endocrinology. I am Company Limited by Guarantee very grateful for the time our big-hitting contributors have given up in order to write for us this Registered in England No. 349408 Registered Office as above time round. Registered Charity No. 266813 ©2015 Society for Endocrinology One of the joys of The Endocrinologist magazine is that it allows us to look at over-arching themes The views expressed by contributors are not necessarily those of the Society. in endocrinology and, in so doing, it brings us all together as an endocrine community. The Society, Editorial Board and authors cannot accept liability for any errors or omissions. Perhaps no publication related to the history of our discipline should omit mention of the OFFICERS name Victor Cornelius Medvei. This man’s enthusiasm and passion for our subject led him Prof S O’Rahilly (President) to write the definitive textbook, A History of Endocrinology, during his retirement. A copy Prof DW Ray (General Secretary) Prof GR Williams (Treasurer) should be on every endocrinologist’s bookshelf. Prof CJ McCabe (Programme Secretary) COUNCIL MEMBERS As clinicians and scientists or mere enthusiasts, we are all continually contributing to Prof E Davies, Prof WS Dhillo, Prof NA Hanley, Prof A Logan, the progress of our subject, and thereby influencing its present and past. Who knows, some Prof JR Seckl, Prof AP Weetman, of you reading today’s magazine may be responsible for major breakthroughs in our specialty, and Dr M Westwood, Prof A White feature in future historical accounts of endocrine discovery ... happy reading! COMMITTEE CHAIRS Clinical: Prof W Arlt Finance: Prof GR Williams BEST WISHES Nominations: Prof S O’Rahilly Nurse: Ms L Shepherd Programme: Prof CJ McCabe MILES LEVY Public Engagement: Prof SA Whitehead Publications: Prof DW Ray Science: Prof KE Chapman Early Career Steering Group: Dr S Mirczuk THE ENDOCRINOLOGIST ENQUIRIES Please contact Jennie Evans [email protected] ADVERTISING You can view this issue online: Please contact [email protected] CONTENTS www.endocrinology.org/endocrinologist ON THE COVER… HEADLINES 30 Get talking to your public, plus SfE BES 3 New Editorial Board members update P6–24 Calls for medallists and nominations HORMONES SfE BES shortlisted for best conference 31 Becoming the leading publisher in endocrinology and beyond THROUGH HOT TOPICS HISTORY NEXT GENERATION 4 The latest endocrine research An endocrine odyssey 32 The New Registrar’s Survival Guide OPINION 33 Trainee benefits of Regional Endocrine Networks IN MY OPINION 27 From our Science and Clinical Committee Correspondents NURSES’ NEWS P26 SOCIETY NEWS 34 Endocrine Nurse Update PHIL 28 Warm welcome for new Officers LOWRY GENERAL NEWS Endocrine secrets of 29 Your views on The Endocrinologist, plus 35 Acromegaly guidelines grant and prize news Review of Endocrinology in Clinical Practice morning sickness Become a contributor… Contact the Editorial office at [email protected] The Society welcomes news items, contributions, article suggestions and letters to the Editor. We would also like to hear your feedback on this issue of the magazine. Deadline for news items for the Summer 2015 issue: 12 March 2015. Deadline for news items for the Autumn 2015 issue: 13 July 2015. Front cover image ©SHUTTERSTOCK 2 | THE ENDOCRINOLOGIST | SPRING 2015 Find us on Facebook & Twitter… facebook.com/SocietyforEndocrinology twitter.com/Soc_Endo HEADLINES NEW FACES AT THE ENDOCRINOLOGIST We’re delighted to welcome Rosemary Bland and SOCIETY Dominic Cavlan (London) as new members of the CALENDAR Editorial Board of The Endocrinologist. Our grateful thanks go to retiring members Karen Featherstone (Manchester) and Olympia Koulouri (Cambridge) for all their hard work and input over the last 2 26 February 2015 years. NATIONAL CLINICAL CASES MEETING The Editorial Board aims to ensure the views and London interests of all Society members are represented and included in The Endocrinologist. If you would 16–17 March 2015 like to contact the Editorial Board with ideas for ENDOCRINE NURSE UPDATE articles, topics or your feedback, please email Rosemary Bland Dominic Cavlan Birmingham [email protected]. 16–18 March 2015 NOMINATIONS FOR CLINICAL UPDATE WHO’S A MEDAL WINNER Birmingham NEXT PRESIDENT IN YOUR FIELD? 12–15 April 2015 Professor Sir Stephen O’Rahilly will retire BNA 2015: FESTIVAL Nominations are sought for the Society’s 2016 Medals. as the Society’s President at the 2016 AGM, The Dale, Transatlantic, Society, Starling, European OF NEUROSCIENCE so a President-elect is sought to commence Edinburgh and International Medals each honour individuals for their role in November 2015. Council’s their significant achievements in endocrinology. Only nominee for this post is Graham Williams 2–4 November 2015 the Society and Starling Medals must be awarded to (Imperial College London). If any SOCIETY FOR Society members; the others are open to any suitable member wishes to suggest an alternative, ENDOCRINOLOGY nominees. The deadline for nominations is 31 July contact Julie Cragg in the Society office BES CONFERENCE 2015. You can find full details and nomination forms at ([email protected]) by 18 March 2015 www.endocrinology.org/about/medals.html . 2015. Edinburgh Look out for the brand new Society for Endocrinology blog, see WITH REGRET www.endocrinology.org/ We were saddened to hear THE ENDOCRINE POST! meetings for full details of the untimely death of endocrinologyblog.org Jenny Pell of the University of Cambridge. Jenny was an active and valued Society NEW COUNCIL AND COMMITTEE GRANT member. She served as MEMBERS NEEDED Senior Editor for Journal AND of Endocrinology (2005–2011), You are encouraged to nominate replacements for Jonathan Seckl, PRIZE on our Science Committee Tony Weetman and Anne White, who retire from the Society’s Council DEADLINES (until 2008) and as a faculty in November 2015, having served their 4-year terms of office. member at the Autumn Endo- Vacancies on the Clinical, Early Career Steering Group, Finance, Nurse, 11 March 2015 crine Retreat (now the Career Programme, Public Engagement and Science Committees will also arise SUMMER STUDENTSHIPS Development Workshops). The at the end of 2015. If you would like to be involved in running your Society extends its condolences Society, please consider standing for election! 15 March 2015 to Jenny’s family and friends. CONFERENCE GRANTS An obituary will appear in our Details and nominations forms are on the specific committee pages at next issue. www.endocrinology.org/about/committee.html. The closing date is 10 April 2015 31 July 2015. EARLY CAREER PRIZE LECTURE ABSTRACTS SPECIAL SfE BES 2014 4 MAY–6 JULY 2015 ISSUES… SHORTLISTED FOR SfE BES REGISTRATION GRANTS Don’t forget that Journal BEST CONFERENCE of Endocrinology (JOE) 27 MAY 2015 The 2014 Society for Endocrinology BES and Journal of Molecular EARLY CAREER GRANTS Endocrinology (JME), which conference has been shortlisted for yet are both Society journals, another award! It is a finalist for ‘Best 27 MAY 2015 publish regular special Association Conference – Outside London’ EQUIPMENT GRANTS issues looking back at in the Association Excellence Awards 2015, the history of endocrine which recognise best practice and excellence 15 JUNE–13 JULY 2015 disorders. Recently, the 20th in professional associations. The SfE BES UNDERGRADUATE anniversary of leptin was conference is our Society’s flagship event, ACHIEVEMENT AWARDS marked in JOE, and 25 years designed to bring together the best in UK and of molecular endocrinology international endocrinology. We are thrilled see were commemorated in JME. that it has been recognised in this way. www.endocrinology.org/ Visit www.try-joe.org and grants for full details of www.try-jme.org for more all Society grants information. THE ENDOCRINOLOGIST | SPRING 2015 | 3 HOT TOPICS HT SOCIETY FOR ENDOCRINOLOGY OFFICIAL JOURNALS Society members have free access to the current content of Journal of Endocrinology, Journal of Molecular