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Biomolecular Materials Program Meeting Sponsored by the Division of Materials Sciences and Engineering (DMS&E) in the Office of Basic Energy Sciences (BES) of the U

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Biomolecular Materials Program Meeting Sponsored by the Division of Materials Sciences and Engineering (DMS&E) in the Office of Basic Energy Sciences (BES) of the U BiomolecularBiomolecular MaterialsMaterials ProgramProgram MeetingMeeting -- 20052005 August 25 – 28, 2005, Airlie Conference Center, Warrenton, VA coexistence Membrane charge density Global [Zn2+] Division of Materials Sciences and Engineering Cover Top Left: Self-assembly of peptide amphiphiles into bioactive nanofibers presenting biological signals at Van der Waals density. Courtesy: Samuel Stupp (Northwestern University) Top Right: Carbohydrate-functionalized polymers designed to mimic the struc- tures of mucin glycoproteins assembled on carbon nanotubes. Courtesy: Carolyn Bertozzi and Alex Zettl (Lawrence Berkeley National Laboratory) Bottom Left: Hierarchy of ion-mediated interactions expressed in self-assembled structures of DNA-anionic membrane complexes. Courtesy: Gerard Wong (The Frederick Seitz Materials Research Laboratory, University of Illinois-Urbana Champaign) Bottom Right: Proteins occluded within these star-burst structures of silica, made by a sponge, have revealed a novel route to the low-temperature catalytic nanofabrication of silica, silicones and semiconductors for energy applications. Courtesy: Daniel Morse (University of California-Santa Barbara) This document describes activities performed under contract number DE-AC05-00OR22750 between the U.S. Department of Energy and Oak Ridge Associated Universities. Foreword This volume highlights the scientific content of the 2005 Biomolecular Materials Program Meeting sponsored by the Division of Materials Sciences and Engineering (DMS&E) in the Office of Basic Energy Sciences (BES) of the U. S. Department of Energy (DOE). This meeting is the first in a series of research theme based Contractors’ Meetings and will focus on BES-funded research at the intersection of physical sciences and biology. The meeting will feature research that cuts across several DMS&E core research program areas. Biomolecular Materials is a relatively new but growing Core Research Activity (CRA) component in DMS&E. This activity formally came into existence following the recommendations of a workshop sponsored by the Basic Energy Sciences Advisory Committee to explore the potential impact of biology on the physical sciences including, in particular the materials and chemical sciences. The major programmatic emphasis is on exploring the molecules, structures, processes and concepts of the biological world that could be used or mimicked in designing novel materials, processes or devices with potential energy significance in support of the DOE missions. The purpose of the Biomolecular Materials Program Meeting is to bring together researchers funded by BES in this new and emerging research area, to facilitate the exchange of new results and research highlights, to foster new ideas and collaborations among the participants, and to identify needs of the research community. The meeting will also help DMS&E in assessing the state of the program, charting future directions and identifying programmatic needs. The agenda reflects some of the major research themes covered within the broad, expanding field of biomolecular materials. Many of the BES Contractors’ Meetings are passing the quarter-century mark in longevity and are very highly regarded by their participants. We sincerely hope that the Biomolecular Materials Program Meeting will join the others in keeping with the long- standing BES tradition. We thank all of the invited speakers and meeting attendees for their active participation in sharing their ideas and research results. The dedicated efforts of the Meeting Chairs, Mark Alper and Dan Morse, in organizing and coordinating the meeting are sincerely appreciated. Thanks also go to Christie Ashton from DMS&E and Brian Herndon and Kellye Sliger from Oak Ridge Institute of Science and Education for their fine work in taking care of logistical aspects of the meeting. Arvind Kini and Tim Fitzsimmons Division of Materials Sciences and Engineering Office of Basic Energy Sciences Office of Science U.S. Department of Energy i U. S. Dept of Energy Office of Basic Energy Sciences Biomolecular Materials Program Meeting August 25-28, 2005 Mark Alper (LBNL) and Dan Morse (UC-SB), Meeting Chairs THURSDAY, AUGUST 25 3:00 – 6:00 pm Registration 5:00 – 6:00 pm Reception (No Host) 6:00 – 7:00 pm ***** Dinner ***** 7:30 pm Introductory Remarks Harriet Kung, Director, Division of Materials Science and Engineering Arvind Kini Program Manager, Materials Chemistry and Biomolecular Materials Session I Self-assembly I – Complex Structures and Systems Chair: Mark Alper, LBNL 8:00 – 8:30 pm Samuel Stupp, Northwestern The Expanding Field of Biomolecular Materials 8:30 -- 9:00 pm Atul Parikh, UC-Davis Patterning and Structure Formation in Fluid Lipid Membranes 9:00 – 9:30 pm Hiroshi Matsui, Hunter College Bionanotechnology Approach in Material Synthesis and Device Fabrication by Applying Peptide/Protein Assemblies 9:30 – 10:00 pm Joanna Aizenberg, Lucent (Invited Talk) Controlling the inorganic crystallization at the organic interface: Lessons from biomineralization iii FRIDAY, AUGUST 26 7:00 – 8:00 am Breakfast Session II Self-assembly II – Understanding and Controlling Self- assembly Chair: Dan Morse, UC-SB 8:30 – 9:00 am George Whitesides, Harvard Dynamic and Static Self-assembly of Meso-scale Objects 9:00 – 9:30 am Paul Alivisatos, LBNL Programmable assembly of nanocrystals using DNA 9:30 – 10:00 am Jennifer Lewis, FS-MRL Bio-Inspired Assembly of 3-D Micro-Periodic Structures 10:00 – 10:30 am ***** Break ***** 10:30 – 11:00 am Zhigang Suo, Harvard Electric field directed motion of molecules on solid surfaces 11:00 – 11:30 am Gordon Osbourn, SNL-NM Programming Dynamic Self-Assembly: Theory and Simulations 11:30 – 12:00 Noon Brian Crane, Cornell (Invited Talk) Structures and Activities of Protein Complexes that Mediate Bacterial Chemotaxis 12:00 Noon –1:00 pm ***** Lunch ***** 1:00 – 4:00 pm Time for Interactions & Discussions 4:00 – 6:00 pm Poster Session I 6:00 – 7:00 pm ***** Dinner ***** Session III Bioinspired/Biomimetic Materials and Assemblies Chair: Yok Chen, DOE 7:00 – 7:30 pm Kent Blasie, U-Penn Design & Structural Characterization of Amphiphilic 4- Helix Bundle Peptides for Novel Electronic and Photonic Biomolecular Materials iv 7:30 -- 8:00 pm Andy Shreve, LANL Control of Optical Properties of Materials Using Bioinspired Assemblies 8:00 – 8:30 pm Zhibin Guan, UC-Irvine Biomimetic Polymer Design at the Interface of Chemistry and Biology 8:30 – 9:00 pm George Bachand, SNL-NM Active Assembly of Dynamic and Adaptable Materials 9:00 – 11:00 pm Continuation of Poster Session I SATURDAY, AUGUST 27 7:00 – 8:00 am Breakfast Session IV Topic: New Tools and Techniques Chair: Richard Kelley 8:30 – 9:00 am Sunil Sinha, UC-SD Using X-rays and Neutrons to probe structual inhomogeneities in membranes and organic films 9:00 – 9:30 am Sow-Hsin Chen, MIT Inelastic X-Ray Scattering Studies of Phonon Propagation and Damping in Biomolecular Assemblies 9:30 – 10:00 am Ben Ocko, BNL X-ray scattering studies of soft matter and biomolecular materials 10:00 – 10:30 am ***** Break ***** 10:30 – 11:00 am Steve Granick, FS-MRL Integrated Platforms for Optical and Force Microscopy 11:00 – 11:30 am Jim DeYoreo, LLNL (Invited Talk) The scanned probe microscope as a platform for in situ imaging, measurement, and manipulation of biomolecular systems 11:30 – 12:00 Noon Janos Kirz, ALS, LBNL (Invited Talk) Toward Structural Biology using the LCLS v 12:00 Noon –1:00 pm ***** Lunch ***** 1:00 – 4:00 pm Time for Interactions and Discussions 4:00 – 6:00 pm Poster Session II 6:00 – 7:00 pm ***** Dinner ***** Session V Biomolecular Functional Systems: Bio/Non-bio Integration Chair: Tim Fitzsimmons, DOE 7:00 – 7:30 pm Jeff Brinker, SNL-NM Cell-Directed Assembly of the Bio-Nano Interface 7:30 – 8:00 pm Millie Firestone (ANL) and Mike Wasielewski (Northwestern) Controlling the Photophysics of Protein Arrays in Thermoresponsive Soft Materials 8:00 – 8:30 pm Dirk Trauner, LBNL Tinkering with Nature's Molecular Machines: Development of Light-Activated Ion Channels 8:30 -- 9:00 pm Jim Heath, Caltech The nano/bio interface for in vitro and in vivo diagnostics of health and disease 9:00 – 11:00 pm Continuation of Poster Session II SUNDAY, AUGUST 28 7:00 – 8:00 am Breakfast Session VI Topic: Biotemplated Materials Synthesis Chair: Arvind Kini, DOE 8:00 – 8:30 am Dan Morse, UC-SB Biomolecular Mechanisms Reveal New Routes to Novel Nanostructured Materials for Energy Applications 8:30 -- 9:00 am Surya Mallapragada, Ames Macromolecular templates for self-assembly of bioinspired nanocomposites vi 9:00 – 9:30 am Matt Francis, LBNL Synthetically Modified Viral Capsids: Building Blocks for Nanoscale Materials 9:30 -- 10:00 am Yongsoon Shin, PNNL Replication of Carbohydrates into Hierarchically- Structured Ceramics 10:00 -- 10:30 am ***** Break ***** 10:30 -- 11:00 am Dan Feldheim, NCSU RNA Mediated Synthesis of Catalysts for Hydrogen Production and Oxidation 11:00 – 11:30 am George Crabtree, ANL Basic Research Needs for Solar Energy Utilization 11:30 – 11:45 am Closing Remarks Mark Alper and Dan Morse, Meeting Chairs Arvind Kini and Tim Fitzsimmons, Meeting Organizers 11:45 am ***** Lunch and Adjourn ***** (Optional Box Lunches Available) vii Table of Contents Foreword......................................................................................................................................... i Agenda .......................................................................................................................................... iii
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