CDH16 recombinant monoclonal Alias: -

antibody, clone CDH16/1532R Gene Summary: This gene is a member of the superfamily, encoding calcium-dependent, Catalog Number: RAB00315 membrane-associated . Mapped to a previously identified cluster of cadherin genes on Regulatory Status: For research use only (RUO) 16q22.1, the gene localizes with Product Description: Recombinant rabbit monoclonal superfamily members CDH1, CDH3, CDH5, CDH8 and antibody raised against human CDH16. CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region Clone Name: CDH16/1532R and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition Immunogen: Original antibody is raised against sequence typical of most classical . Expression recombinant protein corresponding to full length human is exclusively in kidney, where the protein functions as CDH16. the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue Theoretical MW (kDa): 130 development. [provided by RefSeq]

Reactivity: Human,Mouse,Rat References: 1. Kidney-specific cadherin, a specific marker for the Applications: Flow Cyt, IF, IHC-P distal portion of the nephron and related renal (See our web site product page for detailed applications neoplasms. Shen SS, Krishna B, Chirala R, Amato RJ, information) Truong LD. Mod Pathol. 2005 Jul;18(7):933-40. 2. Expression of kidney-specific cadherin distinguishes Protocols: See our web site at chromophobe renal cell carcinoma from renal http://www.abnova.com/support/protocols.asp or product oncocytoma. Mazal PR, Exner M, Haitel A, Krieger S, page for detailed protocols Thomson RB, Aronson PS, Susani M. Hum Pathol. 2005 Form: Liquid Jan;36(1):22-8.

Purification: Protein A purification

Isotype: IgG, kappa

Recommend Usage: Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Storage Buffer: In 10 mM PBS (0.05% BSA and 0.05% azide).

Storage Instruction: Store at 4°C.

Entrez GeneID: 1014

Gene Symbol: CDH16

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