UBE2C Antibody Cat. No.: 25-818

UBE2C Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human UBE2C.

TESTED APPLICATIONS: ELISA, WB

UBE2C antibody can be used for detection of UBE2C by ELISA at 1:62500. UBE2C antibody APPLICATIONS: can be used for detection of UBE2C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

PREDICTED MOLECULAR 20 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

October 2, 2021 1 https://www.prosci-inc.com/ube2c-antibody-25-818.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: UBE2C antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: UBE2C

ALTERNATE NAMES: UBE2C, UBCH10, dJ447F3.2

ACCESSION NO.: NP_008950

PROTEIN GI NO.: 5902146

GENE ID: 11065

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is BACKGROUND: an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

REFERENCES: 1) Ieta, K., (2007) Int. J. Cancer 121 (1), 33-38.

ANTIBODIES FOR RESEARCH USE ONLY.

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