GRIN3B Antibody Cat. No.: 56-326

GRIN3B Antibody

GRIN3B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This GRIN3B antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 904-933 amino acids from the C-terminal region of human GRIN3B.

TESTED APPLICATIONS: IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:10~50

PREDICTED MOLECULAR 113 kDa WEIGHT:

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This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: GRIN3B

Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor ALTERNATE NAMES: subtype 3B, NMDAR3B, NR3B, GRIN3B

ACCESSION NO.: O60391

GENE ID: 116444

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single- BACKGROUND: channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.

REFERENCES: 1) Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :

2) Saus, E., et al.Psychiatr Res (2010) In press :

3) Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)

4) Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)

ANTIBODIES FOR RESEARCH USE ONLY.

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