Annual Report 2007 of Kunming Institute of Botany, Chinese Academy of Sciences
Table of contents
1. MESSAGE FROM THE DIRECTOR GENERAL…………………………………………………………………………………………………………………………………………………………………………………………… 2 2. ORGANIZATION STRUCTURE………………………………………………………………………………………………………………………………………………………………………………………………………………… 4 3. PROGRESS IN SCIENTIFIC RESEARCH………………………………………………………………………………………………………………………………………………………………………………………………… 5 Completion of the Southwest China Germplasm Bank of Wild Species Rated as 2007 Top Ten Pieces of News in Science and Technology in China………………… 6 Breakthrough Made on Mechanism Study of Systemic Resistance Induction of Plant Caused by New Natural Pesticide with Antivirus Activities……………………… 7 New Progress Achieved in Phylogeography Study of Taxus wallichiana complex……………………………………………………………………………………………………………………………… 8 Important Breakthrough Made in Developing New Potential Anticancer Drugs………………………………………………………………………………………………………………………………９ New Progress Made in Mechanism Study of Plant Responses to Low Temperature…………………………………………………………………………………………………………………………10 Important Advances Made in Study on Plant Biodiversity Origin and Evolution Mechanism in Special Habitats of Tibetan Plateau………………………………………………11 'Ninth-Five' Key Program, R&D of New Natural Drugs against Several Serious Diseases, Passed Post-Evaluation…………………………………………………………………………………………12 Stage Achievements Made in Program of Investigation and Evaluation of Biofuel Resources in Yunnan……………………………………………………………………………………………………………13 Breakthroughs Achieved in Breeding New Varieties of Wild Flowers…………………………………………………………………………………………………………………………………………………14 Marked Achievements Made in Innovation and Development of New Natural Drugs……………………………………………………………………………………………………………………………………15 Investigation on Plant Diversity in Hengduan Mountains Area, Sino-Vietnamese Boundary Areas and Indochina Peninsula Successfully Completed…………………16 Compilation of the Botany Volume of the Biology Volumes of the Great Encyclopedia of China Commenced………………………………………………………………………………………………………17 4. ACHIEVEMENTS AND AWARDS…………………………………………………………………………………………………………………………………………………………………………………………………………18 The 2007 State Supreme Scientific and Technological Award Granted to Prof. Wu Zhengyi…………………………………………………………………………………………………………18 Chemical Basic Study of Resource Drug of Higher Fungi…………………………………………………………………………………………………………………………………………………………………20 Study on Genetic Diversity and Endangerment Mechanism of Some Rare and Endangered Plants in Yunnan……………………………………………………………………………21 General Survey of Commercial Fungal Resources and Demonstration of Artificial-Promotion Propagation Techniques in Yunnan…………………………………………………22 Development of Anti-HIV/AIDS Drug, the SH Capsule………………………………………………………………………………………………………………………………………………………………23 5. SCIENTIFIC PUBLICATION AND PATENT APPLICATION………………………………………………………………………………………………………………………………………………………24 6. NEW AND ONGOING NATIONAL RESEARCH PROJECTS………………………………………………………………………………………………………………………………………………………………24 7. INTERNATIONAL AND REGIONAL COOPERATIONS………………………………………………………………………………………………………………………………………………………………………25 International Cooperation Projects Undertaken………………………………………………………………………………………………………………………………………………………………………………25 Organizations Jointly Established……………………………………………………………………………………………………………………………………………………………………………………………………26 International Conferences Sponsored or Co-sponsored by KIB………………………………………………………………………………………………………………………………………………………26 Selected Foreign Affair Activities………………………………………………………………………………………………………………………………………………………………………………………………………27 Cooperation Programs with Enterprises……………………………………………………………………………………………………………………………………………………………………………………………29 Transfer of Achievements…………………………………………………………………………………………………………………………………………………………………………………………………………………29 KIB Shareholding Enterprises……………………………………………………………………………………………………………………………………………………………………………………………………………29 8. CONSTRUCTION OF TALENTS TEAM AND SCIENTIFIC RESEARCH PLATFORMS………………………………………………………………………………………………………………………30 Breakthrough Made in Construction of High-level Talents Team……………………………………………………………………………………………………………………………………………………30 Construction of Platform for Scientific Research………………………………………………………………………………………………………………………………………………………………………………34 9. CONSTRUCTION OF INNOVATIVE CULTURE AND MANAGEMENT SYSTEM…………………………………………………………………………………………………………………………………36 Infrastructure Projects during 'Tenth-Five' and Two Major Projects Passed Acceptance Examination……………………………………………………………………………………………36 KIB Maintained its Leading Role in Public Affairs and Propagandas in CAS……………………………………………………………………………………………………………………………………36 Effectively Implementing CAS Public Affairs Management Standards………………………………………………………………………………………………………………………………37 Outstanding Individuals and Organizations Emerging Continuously in the Institutionalized and Innovative Culture Construct………………………………………………………37 Strengthen Regulation Construction and Standardized Management……………………………………………………………………………………………………………………………………………38 Institute-level ARP System Successfully Upgraded and the Second-phase Program under Preparation………………………………………………………………………………………38 Acceptation Examination of First-Stage Archive Collection to CAS Successfully Completed…………………………………………………………………………………………………………39 Appendix 1: Staff and Students ………………………………………………………………………………………………………………………………………………………………………………………………………40 Appendix 2: List of Publications…………………………………………………………………………………………………………………………………………………………………………………………………………46 Appendix 3: List of Patents Applied and Granted ……………………………………………………………………………………………………………………………………………………………………………63
Annual Report 2007 1. MESSAGE FROM THE DIRECTOR GENERAL
In 2007, the second year of the third- on journals of TOP 15% of the JCR related fields, KIB phase of Knowledge Innovation Program, has made evident progresses in scientific publication, Kunming Institute of Botany (KIB) has both in terms of quantity and in quality of the papers. achieved great progress in terms of In 2007, KIB successfully published articles on some research projects, talents construction, world preeminent journals such as Proceedings of platforms’ establishment for scientific the National Academy of Sciences (PNAS), Molecular research, international cooperation and Ecology and Cell Death and Differentiation. Two industrialization. Besides significant papers of KIB were included into 'One-hundred Most academic achievements, KIB has further Influential International Scientific Papers in China' consolidated its institutionalized and sponsored by Ministry of S&T, namely, 'Natural innovative culture construction in the past Terphenyls: Developments since 1877' published in year. As for national, Chinese Academy Chemical Reviews by Prof. Liu Jikai in 2006 and 'Plant of Sciences (CAS) and provincial projects Cyclopeptides' published in the same journal and the undertaken, KIB has obtained a number same year by Prof. Tan Ninghua and Prof. Zhou Jun, of research funds including one special academician of CAS. project for basic research of Ministry of Construction work of the state key scientific Science and Technology of China (S&T), facilitation project 'The Southwest China Germplasm 22 projects of National Natural Science Bank of Wild Species' has been completed in April Foundation, 14 Yunnan Provincial S&T 2007. Collecting and screening germplasm resources Foundation projects and two Yunnan Talents have also made steady progress. The completion of projects. In addition, KIB participated in the first germplasm bank of wild species in China was two 973 Programs and 10 new international rated as one of the 2007 Top Ten Pieces of News in cooperation projects have been signed up. Science and Technology in China both by academicians In terms of talents construction, Dr. Tan from CAS and Chinese Academy of Engineering Ninghua received a grant from the National (CAE). In addition, the website of Botanical Garden Science Fund for Distinguished Young of Kunming has been made available and the plants Scholars, making herself the seventh winner of various sections were listed in the column 'Plant from KIB, and five high-level faculties were Database' of the webpage. Supported by Great recruited through the Talent Recruiting Plan. Encyclopedia of China Office and Yunnan Education Talents position-classification management Publishing House, the editing work of 'Botany Volume has been initially completed. KIB presently of the Biology Volumes of the Great Encyclopedia of owns 272 graduate students, two doctoral China' formally commenced at KIB. The KIB-National students won 2007 CAS President’s Award Science Library Domain Information Service Station for Excellence and six graduate students formally launched in 2007. won 2007 CAS Honor Awards. Yunnan Green-Land Biological Technology Co., Prof. Wu Zhengyi, academician of CAS, Ltd., a KIB shareholding enterprise, was successfully was granted the State Supreme Scientific listed in the stock market in 2007, setting an and Technological Award in 2007. KIB excellent paradigm for transfer of scientific research received two first-class and one second- achievements at KIB. It also provides valuable class natural science prizes of Yunnan experience and reference for KIB in facilitating Scientific and Technological Award, one industrialization. In the past year, KIB has signed second-class prize of Yunnan Scientific cooperation agreements and memoranda of and Technological Progress Award. With understanding for scientific research with many articles embodied by SCI index numbered organizations including Korean Industry Promotion 202, of which, 34 articles were published Agency, National Institute of Biological Resources
2 Annual中国科学院昆明植物研究所年报 Report 2007 2007 1. MESSAGE FROM THE DIRECTOR GENERAL
of Korea, Sunchon National University, Singapore Temasek Life Sciences Laboratory and the Chinese University of Hong Kong. The cooperation projects between KIB and Mary Kay, NOVATIS are being carried out smoothly. Moreover, KIB has initiated and organized a series of international symposia, workshops and training courses that accomplished beneficial effects with universal praises from Chinese and international participating scientists. International symposia and workshops sponsored by KIB included Inception Workshop on Medicinal and Aromatic Plants Traditional Knowledge Bank in Southwest China, Dialogue Session of Medicinal Plants Conservation in China, India, UK and Himalayan Areas and the 5th International Workshop of Edible Mycorrhizal Mushroom, and proceeded steadily with three projects passing international training courses KIB initiated included the professional acceptance inspection for 'Training Course of Edinburgh, Kunming and completion sponsored by CAS. Five construction Lijiang Horticulture' and 'Workshop on Population projects including the reconstruction project Genetics' and 'Workshop on the Vienna edition of of the Herbarium (KUN) passed the program International Code of Botanical Nomenclature', etc. acceptance inspection sponsored by CAS. Project In 2007, scientists from many countries and of 'Ornamental Foliage and Fruit Plant Garden' academic organizations including American of the Botanical Garden has as well passed National Science Foundation (NSF), Yale University, the inspection and the project of wastewater Wisconsin University, Royal Botanical Gardens treatment plant is under construction with Kew, Royal Botanical Garden Edinburgh, Edinburgh substantial progress. University, University of Bonn and Institute of Depending on full devotion and arduous Ecology and Biological Resources of Vietnam endeavors, KIB has made many significant Academy of Sciences visited KIB and conducted achievements, and KIB will celebrate its 70th wide discussions and exchanges with KIB scientists, anniversary in 2008. In the New Year, we will greatly enhancing KIB’s international cooperation continue our unrelenting efforts and courage to with other research institutes. make even more distinguished achievements. KIB has also made advances in institutionalized Under the direct leadership of Communist Party and innovative culture construction. Through of China (CPC) CAS Committee, together with strenuous efforts, KIB has made steady progress in unrelenting endeavors of the KIB entire staff and implementing the CAS public affairs management graduate students, we would certainly achieve standards and reached two CAS first-class more significant and faster developments in standards in terms of security management 2008, dedicating to the 70th anniversary of KIB. and information propagandas, two CAS second- class standards in archive processing and filing management, respectively. KIB was rated as an 'Outstanding Institution' in propagandizing information about implementation of CAS public affairs management standards, and in assets checking. The civil construction projects
Annual Report 2007 3 2.ORGANIZATION STRUCTURE Biogeography and Ecology Department CAS Key Laboratory of Biodiversity and Biogeography Research Sector State Key Laboratory of Phytochemistry and Plant Resources in West China Laboratory of Ethnobotany
Germplasm Bank of Wild Species in Southwest China
Kunming Institute of Botany Botanic Garden
Supporting Sector Horticulture Center of Botanic Garden
Germplasm Conservation Center
Phytochemistry Analyzing and Testing Center
Herbarium (KUN)
Sci. & Tech. Information Center
General Administrative Office Management Sector
Division of Science and Development & Assets and Finance Management
Division of Human Resources, CPC and Education Affairs
Institute of Tibetan Plateau Research at Kunming, CAS Conjoint Units Center for Mountain Ecosystem Studies
Lijiang Alpine Botanic Garden Botanical Society KIB-Mary Kay Joint Lab of Yunnan
Logistics Center
4 Annual中国科学院昆明植物研究所年报 Report 2007 2007 3. PROGRESS IN SCIENTIFIC RESEARCH
With the CAS Key Laboratory of Biodiversity and Biogeography, State Key Laboratory of Phytochemistry and Plant Resources in West China, the Southwest China Germplasm Bank of Wild Species and the Botanical Garden as the basic research units and scientific research platform, KIB, in 2007, consecutively dedicated its efforts in aiming the scientific frontiers of international botanical science and biodiversity conservation researches according to China’s strategic needs, especially to the ambitious West Exploration Program, KIB devoted to underscoring originally scientific innovation, strengthening strategic high-tech innovations and made great progress in biogeography, phytochemistry, plant genomics, conservation biology, developing of new drugs and utilization of plant resources. Relying on these achievements, KIB has made important contributions to sustainable utilization and conservation of biodiversity, regional economic development and social progress.
Annual Report 2007 5 Completion of the Southwest China Germplasm Bank of Wild Species Rated as 2007 Top Ten Pieces of News in Science and Technology in China
With total investment valuing RMB 148 million yuan, the were gathered with digital expression and number Southwest China Germplasm Bank of Wild Species is a for information sharing exceeded 10000 and 1764 state-key science facilitation project. According to the accessions of 710 species can be shared in form blueprint, the germplasm bank consists of seed bank, of actual specimens, through e-platform and the DNA bank, plant germplasm in-vitro, microorganism networking system of the Southwest China Germplasm bank, animal germplasm, information center and Bank of Wild Species. In gathering, screening and research laboratory, etc. Centering on conservation conservation of the germplasm resources, special of germplasm of wild species in Yunnan and in attention was attached to rare and endangered plant adjacent areas (including Qinghai-Tibetan Plateau), species, such as Paraisometrum, Nyssa yunnanensis the main species gathered are plant germplasm and Taxus. Based on the previous work, the ambitious resources, containing some animal and microorganism goal of gathering will be achieved, which would make resources. The construction of the bank would provide important contributions to implementing international technological supports and basis of decision-making conventions, effective conservation of biodiversity and for conservation, studies, development and effective to sustainable development. �������������������������Completion of the South- utilization of germplasm resources of wild species in west China Germplasm Bank of Wild Species was voted China. In five years, 66500 accessions of 6450 species, as 2007 Top Ten Pieces of News in Science and Technol- will be collected and preserved at the germplasm bank, ogy in China voted by an evaluation group consisting of and the number will climb to 190000 accessions of 574 academicians from CAS and CAE. 19000 species in fifteen years. The ultimate goal of the bank is to be a world-class, integrative germplasm bank and scientific facility for conservation of wild species, ensuring the security of China’s strategic biological resources. The germplasm bank will supply materials and information for development of industry and researches of life sciences so as to facilitate the sustainable development of biotechnological industry and social economic development in China and to lay a material foundation for fulfilling the goal of effective biodiversity conservation and strategy of sustainable development. The principal part of the germplasm bank project passed the acceptance inspection in 2007. Relying on support of the Scientific Basic Platform Construction Program, KIB successfully initiated the program of standardized screening of 13708 accessions of 3000 species, which involved with 206 persons of 15 institutions from varied areas of Southwest China, Central China, Northwest China, North China, South China and East China. In addition, 15028 accessions
6 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Breakthrough Made on Mechanism Study of Systemic Resistance Induction of Plant Caused by New Natural Pesticide with Antivirus Activities
Plants have evolved multiple mechanisms to selectively as models, studies on the action mechanism revealed suppress pathogens by production of secondary that the compounds predominantly suppress the metabolites. Therefore, direct selections for antiviral expression of viral subgenomic RNA(s) without affecting compounds from plants can be used to identify new the accumulation of viral genomic RNA. Their work agents with potent antiviral activity but not toxic to suggested that the viral subgenomic RNA could be a new hosts. In collaboration with CAS Institute of Microbiology, target for the discovery of antiviral drugs, and that seco- Institute for Viral Disease Control and Prevention, pregnane steroid and its glycosides found in the two Chinese Center for Disease Control and Prevention (China kinds of medicinal herbs have the potential for further CDC) and Institute of Biotechnology, Yunnan Academy of development as antiviral agents against alphavirus-like Agricultural Sciences (YAAS), the research group led by positive-strand RNA viruses. This study was published in Prof. Hao Xiaojiang, for the first time, found that a class the journal of PNAS (PNAS, 2007, 104(19): 8083-8088). of compounds, seco-pregnane steroid glaucogenin C and its monosugar-glycosides are effective and selective inhibitors to alphavirus-like positive-strand RNA viruses including plant-infecting tobacco mosaic virus (TMV) and animal-infecting Sindbis virus (SINV), eastern equine encephalitis virus (EEEV), and Getah virus (GETV), but not to other RNA or DNA viruses, yet they were not toxic to host cells. In vivo administration of the compounds protected BALB/c mice from lethal SINV infection without adverse effects on mice. Using TMV and SINV
Annual Report 2007 7 New Progress Achieved in Phylogeography Study of Taxus wallichiana Complex
China is one of the distribution centers of Taxus wallichiana plants complex and the State Council included T. wallichiana into the list of state key wild plant species (volume A) in 1999. However, species number of T. wallichiana complex distributed in China remains a problem with major viewpoint divergence in the status of Chinese yew, South China yew and Himalayan yew distributed ranging from mountainous region of Southeast China to Himalayan areas. Since 2004, the research group led by Prof. Li Dezhu, in cooperation with Royal Botanical Garden Edinburgh, has spent over three years collecting a total of 1235 individuals from 50 populations from 14 provinces of China including Yunnan, Sichuan, Shannxi, Guizhou, Guangxi, Guangdong, Hunan, Hubei, Henan, Anhui, Zhejiang, Jiangxi, Fujian and Taiwan, and North Vietnam for analyses. The study, jointly supported by CAS and the Royal Society of London, distinguished 19 different chloroplast haplotypes of the compex using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for chloroplast DNA variation. The researchers found a very high level of population differentiation and a strong phylogeographic pattern. Haplotype differentiation was most marked along the boundary between the Sino-Himalayan and Sino-Japanese Forest floristic subkingdoms. The researchers concluded that several localized refugees existed during the last glaciation from which the present-day distribution of Himalayan yew may be derived. This study is published in the journal of Molecular Ecology (2007, 16(22): 4684-4698).
8 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Important Breakthrough Made in Developing New Potential Anticancer Drugs
In collaboration with State Key Laboratory of Medical primary t(8;21) leukemia blasts and caused AML1- Genomics in Shanghai Jiao Tong University, Shanghai ETO degradation. The high-degree selectivity and Institutes for Biological Sciences in CAS, and Rui Jin low-concentration medical effect suggested that EriB Hospital, Prof. Sun Handong, academician of CAS, might be a low-toxicity, high-performance molecular- observed significant apoptosis of t (8; 21) chromosome targeted agent, with great potential to candidate drug translocation through NF-κB and MAPK pathways, for targeting therapy of AML-M2b type leukemia. concomitant with caspase-3 activation. AML1-ETO oncoprotein was degraded in parallel to caspase-3 activation. The study was published in the journal of Cell Death and Differentiation (2007, 14(2), 306- 317). Through profound studies on the medicinal mechanism of eriocalyxin B (EriB), which was tested on AML-M2b leukemia cells, the researchers concluded that Kasumi-1 and AML-M2b murine leukemia cells were most sensitive to EriB (even at μ M level) with significant apoptosis. EriB-mediated apoptosis was associated with NF-κB inactivation by preventing NF- κB nuclear translocation and EriB was effective on
Annual Report 2007 9 New Progress Made in Mechanism Study of Plant Responses to Low Temperature
Low-temperature stress is a major environmental phospholipid hydrolysis in freezing and post-freezing factor effecting the growth, geographic distribution and recovery. Thus the changes of membrane lipids in two yields of plants, and damages resulted from cold and ecotypes and four genotypes during three phases of freezing stress usually occurred in membrane. Changes Arabidopsis thaliana freezing tolerance were analyzed in membrane lipid composition play important roles in and determined in details, laying an important plant adaptation and survival after freezing. Plants’ formation for further elucidating the mechanism of response to cold and freezing involves three distinct plants responses to low temperature. The results were phases: cold acclimation, freezing, and post-freezing published online on The Journal of Biological Chemistry recovery. In collaboration with American scientists, in Dec. 2007, and the paper was rated as one of the the research group led by Prof. Li Weiqi carried out outstanding scientific achievements of China Mainland the study on how the 120 lipid species change during and Hong Kong by the magazine Nature China. freezing and post-freezing recovery of Arabidopsis thaliana freezing tolerance, and on the effect of two phospholipase D (PLD), PLDα1 and PLDδ during these phases, using lipidomics based on ESI-MS/MS. The results showed that different type of lipids and lipids of different cellular orientation react differently during freezing and post-freezing recovery, and suppression of PLDα1 and PLDδ resulted to different effects on
10 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Important Advances Made in Study on Plant Biodiversity Origin and Evolution Mechanism in Special Habitats of Tibetan Plateau
Main contents of the project presided by the research Tertiary flora also profoundly influenced the flora of group of Prof. Sun Hang contain three aspects, namely, this area. Evidence obtained as well suggested that characteristics of Tibetan Plateau, evolution model of Bering dispersal route played a critical role in forming representative populations, biodiversity mechanism the flora of this area through molecular biogeography and evolution speed, species adaptation mechanism analyses. Both vicariance and dispersal are important under extreme environmental conditions and features causes for the flora distribution. Under the extreme of reproductive biology, and chromosome ploidy environmental conditions, plants also developed many evolution under extreme environmental conditions special adaptation structures, which have multiple of Tibetan Plateau. The results demonstrated that ecological functions, ensuring their survival and plant diversity of this area involves background of evolution under tough habitats. A total of 53 articles flora of Tethys, and that many plants with shorter have been published for this project, among which 38 evolution history result from rapid uplift process of are published in SCI-embodied journals including top the plateau. According to cytological studies, flora of 15-30% journals of the same field such asMolecular this area owns great potential for further evolution, Ecology, American Journal of Botany, Moleculer whether in terms of representative populations under Phylogenetics and Evolution, Annals of Botany, etc. extreme conditions, or of general level. And natural hybridization probably functions as one of the drives for evolution. On the other hand, dispersal of Arctic-
Annual Report 2007 11 'Ninth-Five' Key Program, R&D of New Natural Drugs against Several Serious Diseases, Passed Post-Evaluation
In Sep. 2007, a post-evaluation was carried out on As for biotechnological drugs, two certificates for new the CAS 'ninth-five' key and special-support program, drugs, one approval for clinical trials of new drugs R&D of New Natural Drugs against Several Serious and one new drug certificate for clinical laboratory Diseases, co-chaired by Prof. Hao Xiaojiang from KIB, kit have been obtained. To date, industrialization of Prof. Ding Jian from Shanghai Institute of Materia several researching results has already accomplished Medica, CAS and Prof. Li Boliang from Shanghai enormous economic and social benefits. Institute of Biochemistry, CAS. The post-evaluation conducted by CAS Program Evaluation and Supervision Center by a group of leading scholars and experts including CAS academicians, Prof. Chen Kaixian and Prof. Sun Handong, and Profs. Ma Hongjian, Kong Lingyi, Du Guanhua, Lin Wenhan, senior chemist Mr. Yang Lahu and Prof. Zhang Guolin, etc., achieved satisfying results. After termiation of the program, important progress has been made on basis of previous research results and a series of achievements been fulfilled: five new drugs obtained drug approval numbers and another five new drugs obtained approval for clinical trials, one new drug completed clinical trial (phase III) and the application for new drug certificate is being conducted. Three new drugs owning independent intellectual property rights (IPR), on which preclinical researching work have already been finished, obtained approvals for clinical trials successively.
12 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Stage Achievements Made in Program of Investigation and Evaluation of Biofuel Resources in Yunnan
As one of the most ancient energy source for human develop the industry of Jatropha curcas were outlined, and an important renewable energy resource, biofuel which can be extremely valuable data and reference resource is very important, and accelerating the for the industrial development planning of Jatropha development and utilization of biofuel resource has a curcas in Yunnan. The program has already evaluated great significance. Supported by Yunnan Provincial the acceptance inspection by a group of experts Development and Reform Commission, a research sponsored by Yunnan Provincial Development and group consisting of scientists of multiple disciplines Reform Commission. including plant taxonomy, plant introduction and cultivation, molecular biology, plant physiology, phytochemistry and ethnobotany, has investigated and gathered basic informative materials concerning biological, ecological and economic characteristics of Jatropha curcas in a short period of time. Through additional field surveys and studies on chemical components of the plant oils, the research group has thoroughly and systematically analyzed and summarized the geographic distribution of Jatropha curcas in whole Yunnan, parts of Sichuan and Guangxi provinces, with information of the resource quantity, ecological and biological features, optimum habitats for, targeted biomass per unit area and chemical property of plant oil, etc. Meanwhile, the research group has carried out complete analyses and evaluation on climatically and geographically optimum regions for plantation of Jatropha curcas, principles for industrial development planning and challenges for Yunnan to
Annual Report 2007 13 Breakthroughs Achieved in Breeding New Varieties of Wild Flowers
The research group led by Prof. Zhang Changqin the State Forestry Administration. has been engaging in breeding of new varieties of At the same time, the research group led by Prof. alpine wild flowers, especially of introduction and Gong Xun has developed a new cultivar of Michelia domestication of rhododendron for many years. After figo, M. figo 'Wanchun' which passed the evaluation 20 years’ efforts and on basis of the 126 domesticated by experts sponsored by the New Variety Office of varieties of Yunnan wild rhododendron and hybridized State Forestry Administration. Through five-year breeding, the research group has started bud and observations and studies on innovation, specificity, sprout breeding recently and successfully developed consistency and stability, the research group finished six rhododendron varieties, i.e. Rhododendron. studies on cutting propagation, tissue culture and 'Hongyun', R. 'Xuemeiren', R. 'Jinzhizhu', R. 'Ziyan', R. cultivation technology. With distinguished horticultural 'Jiaoyan' and R. 'Xilinmen'. All the six varieties passed characters and strong adaptation ability, the M. figo substantial examination by experts of the same field 'Wanchun' is very suitable for garden greening. It organized by the New Variety Office of State Forestry is the first M. figo cultivar and evergreen variety of Administration. Magnoliaceae that apply for state-level protection for These six new cultivars are innovative, special, new plant varieties. constant and stable with scientific names, which accords to the conditions described by International Code of Nomenclature for Cultivated Plants and new horticultural cultivars. Technological propagation studies on cutting and sowing of the identified rhododendron cultivars have been already carried out and initial results been achieved. These new cultivars are the first new rhododendron varieties evaluated by
14 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Marked Achievements Made in Innovation and Development of New Natural Drugs
Natural drug has been an indispensable part of world AIDS drug, Qishile capsule, Emei-glucoside capsule pharmacology. Discovering various physiological against gynecology hemostasis, hypoglycemic drug, activities and drug lead compounds from natural drugs CA-1 and cough-reliving drug, dengtaiye. Drugs under and ethno-pharmacology plays a critical role in R&D clinical trials include: anti-HIV/AIDS candidate drug, of new drug with independent intellectual property schizandrin and Flazin, anti-leukaemia candidate drug, right. Development of new natural drugs on basis of diterpenoids, anti-depression candidate drug, CXZ- elucidating activity components of traditional drugs 123, lipase inhibitor, vibralactone, antitumor candidate is the current trend. KIB has already constructed a drugs, GC-51, actaea asiatica and sesquiterpene from talents’ team for R&D of new drugs with independent Inula britannica, etc. intellectual property rights, which consists of experts mainly from the State Key Laboratory of Phytochemistry and Plant Resources in West China, and from other departments as well. New drugs under clinical trials: clinical trials of anti-HIV/AIDS drug, SH capsule have been completed in Thailand (transferred); clinical trials (phase III) of the new drug against cardio-cerebral vascular diseases, Denzhanxixin injection and clinical trials (phase I) of the new drug against presenile dementia, phenchlobenpyrrone have been completed, respectively. Approvals for clinical trials of cepharanthine hydrochloride and cepharanthine hydrochloride injection have been obtained. New drugs with completion of preclinical studies include anti-HIV/
Annual Report 2007 15 Investigation on Plant Diversity in Hengduan Mountains Area, Sino-Vietnamese Boundary Areas and Indochina Peninsula Successfully Completed
The fourth Sino-American joint investigation on plant collected samples of diversity in Hengduan Mountains Area co-sponsored some epiphytic plants by KIB and Harvard University lasted one and a and populations of half months and length of the journal exceeded five Caryota urens. Sino- thousand kilometers. This investigation has finished Vietnamese boundary the basic material-gathering in weakened and key area of Yunnan is one areas for plant diversity in Northwest Sichuan. The of the most crucial plant populations investigated covered seed plants, regions linking China fern flora, bryophytes and higher fungi and key places and flora of Indochina surveyed were mainly dry-warm and dry-hot valleys, Peninsula. It’s not screes, alpine meadow, and vegetation types of only the important part of the center of ancient, special primary forests and secondary forests. The obtaining plants in Yunnan, Guizhou and Guangxi of China, but of basic information of large-quantity plants from also is the core part of Southeast Yunnan Center, which weakened and key places in Hengduan Mountains is one of the two biodiversity centers in Yunnan. The investigation results will be published in the magazine Areas, such as alpine-cold quillwort, Ranunculaceae National Geographic. and Kingdoniaceae, laid an important foundation for Owing to support of National Geographic Society biogeography studies on important populations and of USA, KIB scientists carried out the program of for exploring the origin and evolution of representative the second-phase investigation on fern in Indochina populations of this area. This study will as well provide Peninsula. With extremely friendly reception and beneficial theoretic and technological suggestions and support of Laos Traditional Medicine Research Center references for protection of endangered plants and (TMRC), the scientists visited central areas of Laos, construction of natural reserves. such as Ganmeng Province, Bolikansai Province and Supported by the National Geographic Society of Wanrong District of Vientiane. This field investigation USA, KIB investigation team successfully completed gathered several hundred specimens, some spores the first investigation research on vascular plants and materials for molecular studies. For the fist time, in Sino-Vietnamese boundary areas of Yunnan. The a systematic survey and study on fern in Laos was investigation team has taken a total of over 6000 field carried out. photos and gathered more than 600 specimens, and
16 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Editing Work of Botany Volume of the Biology Volumes of the Great Encyclopedia of China Commenced Due to support and concerns from Great Encyclopedia culture, symbolizing China’s outstanding contributions of China Office and Yunnan Education Publishing to the human civilization. Using scientific classification House, inception meeting for the editing work of methods, a complete, scientific and systematic 'Botany Volume of Biology Volumes of the Great compilation and filing of cultural masterpieces from Encyclopedia of China' was held at KIB from June 26- pre-Qin to 1911 revolution will be carried out firstly 27, 2007. KIB and CAS Institute of Botany are the so as to provide accurate, detailed materials for principal editing institutions for the Botany Volume, the academia and related departments. The Great with Prof. Li Dezhu, director general of KIB and Encyclopedia of China now includes books on natural Prof. Ma Keping, director general of CAS Institute of sciences for the first time, with evident features of Botany as the editors-in-chief, Prof. Peng Hua and Dr. the times. The completion of the encyclopedia will Wang Jinxiu as the vice editors-in-chief. The editing benefit the entire Chinese people. The editing of the committee totally consists of 18 experts. Relying on Plant Volume of the encyclopedia is general collection recommendation and encouragements by Prof. Wu of books on botanical knowledge before 1911, which Zhengyi, academician of CAS and editor-in-chief of will reflect the overall comprehending to botany of Biology Volumes of the Great Encyclopedia of China, an entire Chinese people, and will record the materials of editing team consisting of senior experienced experts plant diversity and its changes ever occurred in China and young scientists has already been constructed, throughout the Chinese history. Such editing work of laying a firm intellectual foundation for editing of the the encyclopedia will link different generations and encyclopedia. syncretize knowledge of ancient and modern times It’s a traditional convention to edit encyclopedia with great significance. in prosperous age throughout the history. In the important stage of constructing a moderately prosperous and harmonious society, the central government of China determined to compile the Great Encyclopedia, which is not only requirement for heritage and developing excellent Chinese culture, but also a must for construction of socialist culture with Chinese characteristics and new marked contribution to the world’s civilization. Tremendous amount cultural classic books are the main carries of Chinese thousands’ years of splendid
Annual Report 2007 17 4. ACHIEVEMENTS AND AWARDS
The 2007 State Supreme Scientific and Technological Award Granted to Prof. Wu Zhengyi
Prof. Wu Zhengyi, a CAS academician and Emeritus Director of KIB was granted the State Supreme Scientific and Technological Award in 2007.
Born in Jun. 1916 and graduated from Tsinghua plant taxonomy, systematic botany, floristic geography, University Department of Biology in 1937, Prof. Wu and conservation and utilization of plant resources in became a member of China Democratic Alliance in China and elsewhere in the world. Prof. Wu has been 1945 and a CPC member in 1946. In Jun. 1949, he actively involved in one of the largest floristic projects became vice head of the Higher Education Division in the world, Flora Reipublicae Popularis Sinicae (FRPS), of Beijing Municipal Military Control Commission. which is the most comprehensive work of its kind Later on, he entered CAS in December of the same that characterizes plant species and their distribution year, where he went on to fill a string of prestigious in China, and also is a marked achievement of three positions, including secretary of the CPC Branch generations of botanists. He plays a crucial role in the Committee of CAS, Deputy Director of CAS Institute project and has made unparalleled contributions to the of Plant Taxonomy (1950), Member of Biology Division compilation of FRPS. of CAS (1955), Director of KIB (1958-1983), Member Prof. Wu participated in and directed several of the Presidium of Academic Divisions of CAS (1981), investigation projects of plant resources in China. In and Director Emeritus and Professor of KIB, his all, he authored or co-authored 1766 taxa (species current positions. Prof. Wu, who has been engaged in or genera) of plants, the highest among all Chinese botanical research and education for 70 years, is a botanists. world-famous botanist and an authority in the fields of
18 Annual中国科学院昆明植物研究所年报 Report 2007 2007 It is his critical contribution that terminated the history germplasm bank of wild species, which received that flora growing in China was largely named by concerns from the central government and top leaders. foreign botanists. He worked on all vascular plants in Now numerous natural reserves and the germplasm China and managed to identify their total number. He bank of wild species have been constructed. Prof. Wu’s successfully worked out major patterns of distribution work plays a critical role in conservation of biodiversity of seed plants in China and their composition, roles, and sustainable utilization of resources in China. positions, relationships and evolutionary processes. Wu Zhengyi has published more than 140 papers, He proposed the new theory of 'Eight-Class System of including 75 SCI-embodied articles, and edited (or Classification of the Angiosperms'. co-edited) over 20 monographs, for instance, Flora In terms of floristic geography, Prof. Wu greatly Reipublicae Popularis Sinicae, Flora of China, Flora put forward the floristic geography theory to explain Xizangica, Flora Yunnannica. In recognition Wu’s great the origin and evolution of Chinese plants, forming contributions, he has been awarded many scientific a string of innovative researching thoughts and prizes including the International Cosmos Prize, six methodologies on floristic geography. He pointed out National Scientific Awards, one international award and the phylogenic relations between Chinese flora and the honor of Outstanding Worker of National Science that of tropical area, and revealed the distributional Congress. patterns of Chinese flora and their role in a global Preciseness personified, Prof. Wu has cultivated a context. He modified the system of floristic regions of great many excellent scholars and scientists who have the world, making significant contributions to studies already become senior scientists and project leading on biodiversity. experts of varied research fields. Wu now still engages Wu’s contributions also lie in the effective use of in research work and became the editor-in-chief of the plant resources and conservation of plant diversity in Biology Volumes of the Great Encyclopedia of China. China. At the beginning of the founding of the People’s He has even published important papers in recent Republic of China, he was in charge of a project of years. introducing rubber trees in subtropical areas, and with For his deep understanding on flora, Prof. Wu is other colleagues, he resolved a series of technological one of the most famous botanists in the world. He has problems concerning cultivation of rubber trees, made basic, innovative and forecasting contributions tremendously lessening the imperative problem of to botany and protection and use of plant resources lacking strategic resources of China. His research in China. Obtaining of the State Supreme Scientific greatly facilitated the exploration, development and Technological Award is not only a recognition and & utilization and introduction & domestication of praise for his distinguished contributions, but also a plant resources in China. He was the first to call for proud for all plant scientists in China. the foundations of national natural reserves and a
Annual Report 2007 19 Chemical Basic Study of Resource Drug of Higher Fungi
Type and Class of Award: Science and Technology Progress of Yunnan Natural With evident characteristic and creativity, this Science, First-class Award achievement made important contributions to rational Completion Unit: use and development of higher fungi resources in Kunming Institute of Botany, Chinese Academy of China, and especially in Yunnan. The experts from the Sciences evaluation team unanimously rated this achievement to Main Contributors: be internationally 'advanced-level' among researches Liu Jikai, Wang Fei, Dong Zejun, Qin Xiangdong, Liu of the same field and some results to be internationally Dongze, Tang Jianguo 'leading-level'. Main Contents and Impacts: This program carried out systematic studies on chemical components and biological activity of some higher fungi in Yunnan. Studies on chemical components of over 50 kinds of wild higher fungi and screening of medicinal activity of higher-fungi fruit bodies and fermentation broth extract have been completed. Through this study, over 300 kinds of compounds have been identified, 100 of which are new compounds (three compounds with new structure framework). A great many natural components with innovative structures and biological activity have been obtained. The founding of concentricolide, a compound that can inhibit HIV-1 virus, cell-binding and cell fusion, vibralactone, natural activity substance strongly inhibit the activity of pancreatic lipase and grifolin, a compound used for tumor signal molecular conductive and for induction of cell apoptosis is of great innovation. One monograph named Higher Fungi Chemistry has been published, which will greatly facilitate the studies on higher fungi. A total of six patents have been obtained and 53 articles, including 46 SCI-embodied articles (213 times for citation) been published. Among the articles two (impact factor in 2005 was 20.869) were published on the world famous journal Chemical Reviews sponsored by America Chemical Society.Three compounds were included into the list of 'research hotspot' by the preeminent journal Natural Product Reports , suggesting the academic influences of the research group in the field of higher fungi chemistry.
20 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Study on Genetic Diversity and Endangerment Mechanism of Some Rare and Endangered Plants in Yunnan
Type and Class of Award: Using molecular biology methods, the genetic diversity and structures of national protection plants, Science and Technology Progress of Yunnan Natural including Cycas guizhouensis, Cycas balansae complex, Science First-class Award Paeonia delavayi, Citrus hongheensis and Nouelia Completion Unit: insignis were studied and relations between genetic Kunming Institute of Botany, Chinese Academy of models and species endangerment analyzed. Sciences For the first time, cytological studies on some Main Contributors: Chinese unique plants and plants with higher utilization Gong Xun, Pan Yuezhi, Xiao Longqian, Luan value, such as Paeonia delavayi, Cycas, Calycopteris, Shanshan, Tian Bo, Yang Shuda, Yang Zhiyun, Yang Anemoclema glauciifolium, Heteroplexis microcephala, Yang Psammosilene tunicoides were undertaken and relative Main Contents and Impacts: basic materials have been accumulated. This program carried out complete and profound A total of 24 articles concerning the research results surveys on rare and endangered plants in Yunnan and have been published including eight SCI-embodied Southwest China, and elucidated the patterns and articles with total IF value amounting to 15.502, status of their geographical distribution, especially the on preeminent journals, such as Annals of Botany, endangerment of some populations, for instance, the Australian Journal of Botany and Biodiversity Science, Extinction in the Wild (EW) of Poncirus polyandra and etc. almost EW of Cycas multipinna and C. longipetiolula. In summary, this achievement is multiple-level, Through this program, more than 180 species of systematic and profound research on rare and rare and endangered plants and some rare germplasm endangered plants in Yunnan, accumulating basic genes have been conserved. The growth mechanism information materials of these plants. This program as and adaptation capacity of preserved species in the well discussed the endangerment mechanism of these ex situ reserves have been identified. In addition, rare and endangered plants in terms of reproductive population rebuilding experiments on species including biology and genetic diversity, and proposed effective Manglietiastrum sinicum, Parkmeria yunnanensis, measures for plant protection. The research group Manglietia aromatica, Liriodendron chinense, Cycas has successfully published three articles in the journal tanqingii, Manglietia insignis from the experimental Annals of Botany , and the research results of this regions of Xichou Xiaoqiaogou Reserve and Jinping program reached internationally leading level with Fenshuiling Reserve were conducted to increase the important theoretic significance and great potential in population number. plant conservation. Moreover, studies on reproductive process including forming of megaspore and microspore, male and female gametophytes, pollination, fertilization were carried out to explore the endangerment mechanism from the perspective of reproductive biology, based on which relative protection countermeasures will be proposed.
Annual Report 2007 21 General Survey of Commercial Fungal Resources and Demonstration of Artificial-Promotion Propagation Techniques in Yunnan
Type and Class of Award: Approximate Percentage of Trade of Each Kind Science and Technology Progress of Yunnan Natural of Wild Fungi Science Second-class Award Completion Unit: Kunming Institute of Botany, Chinese Academy of Sciences, Lancang Bureau of Science and Technology, Puer, Yunnan Main Contributors: Liu Peigui, Wang Xianghua, Yu Fuqiang, Zheng Huanti, Chen Juan, Chen Jiyue Main Contents and Impacts: Wild edible mushroom is the first-class, large-volume, non-timber product for exportation in Yunnan, which plays an increasingly important role in ecological environment construction and social and economic development. This program engaged in complete and systematic studies on the special industry in Yunnan, wild commercial mushroom industry. On basis of surveys on large number of agricultural product trading markets and wild investigation, the program carried out modifications for the previous classification of commercial fungi and provided additional descriptions in details. A number of new species and specimens have been renamed and recorded with correct names and classification. A total of 22 articles and one practical pictorial handbook have been published through this program. The gathering of commercial fungi species, which laid an important foundation, and screening and identification of key populations, which provided important theoretic basis for protection and utilization of them, are both revolutionary work with great significance. In addition, the public scientific- knowledge promotion campaigns and training courses on technology dissemination of this program also won wide praises. Great progresses have been achieved in artificial synthesis of three important mycorrhizal fungi and mycorrhiza of population plant species and human-power cultivation experiment technology of Lactarius volemus, generating tremendous influences in local area and inaugurating a new way for facilitating volemus and artificial synthesis of mycorrhiza all economic development and fulfillment of sustainable reached internationally leading level. The scientific- utilization of wild edible fungi under forestry. knowledge campaign accords to the development level Such technology with originality is widely cited in mountainous areas. Generally, this achievement is by similar scientists, causing general concerns. The the first creative outcome in the technological field articles published on classification and resources of of commercial fungi, which would play an important commercial fungi are of the same level with similar role in facilitating and guiding further studies on projects in foreign countries and the identification mycorrhizal edible fungi and the development of wild of key population, cultivation technology of Lactarius edible fungi industry in Yunnan.
22 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Development of Anti-HIV/AIDS Drug, SH Capsule
Type and Class of Award: Science and Technology Progress of Yunnan Science contributions to popularizing Traditional Chinese and Technology Progress Second-class Award Medicine throughout the world, by means of cooperation with America and Thailand and Completion Unit: construction of platform for studies on HIV/AIDS and Kunming Institute of Botany, Chinese Academy of market cooperation. Sciences This achievement is leading in studies on development of anti-HIV/AIDS herbal medicine and Main Contributors: revolutionarily established the effect-evaluation system Luo Shide, Wang Yifen, Lai Guofang, Cao Jianxin, and standard of studies of anti-HIV/AIDS herbal Wang Lihong, Hao Xiaojian, Ju Peng, Wang Qiong, medicine. SH capsule now is used in Thailand and Wang Yunsong, Zhu Xiangdong, Cao Xujun tremendous social and economic benefits have been Main Contents and Impacts: achieved, which received wide recognition and praises there, setting an example for development of TCM in Since 1987, this program started screening anti-HIV overseas market. This program as well eliminated the activity from different parts and solvent extracts of doubts on effects of traditional medicine in treatment over 1000 species of herbal plants and found that of HIV/AIDS, advocated that traditional medicine has more than 100 herbal plants demonstrated anti- similar effects with chemical medicine in treatment of HIV activity, over 20 plants demonstrated strong HIV/AIDS. Such a program, which has established the inhibiting activity. Monomeric compound with strong guiding principles for fast, high-efficiency clinical trials anti-HIV activity was obtained. of traditional medicine, will greatly facilitate the HIV/ Based on such results, several articles and AIDS researches in China and the whole world. monographs were published, providing references and guidance for HIV/AIDS treatment using traditional medicine and R&D of anti-HIV/AIDS drugs. These publications were as well frequently cited by scholars and scientists engaging in the same field throughout the world. Such studies ensured China’s leading role in the research field of anti-HIV/AIDS drugs and this achievement has been the frontier research that was focused and followed by scientists, both domestic and international. SH capsule with white mulberry root-bark as the main components demonstrated strong anti-HIV/ AIDS activity and clinical trials revealed that SH capsule can decrease the virus level significantly and enhance immune function with no distinct side- effects. This achievement enormously enriched the research on anti-HIV/AIDS drugs and made important
Annual Report 2007 23 5. SCIENTIFIC PUBLICATION AND PATENT APPLICATION
In 2007, a total of 202 SCI-index articles have been published, among which 147 articles were published with KIB as the first author, 34 articles were published on journals of top 15% of relevant subjects. CSCD-index articles published later year number 101, including 56 articles with KIB as the first author. Two papers were included into the first 'One-hundred Most Influential International Scientific Papers in China' sponsored by Ministry of S&T, namely, 'Natural Terphenyls: Developments since 1877' published in Chemical Reviews (2006, 106(6): 2209-2223) by Prof. Liu Jikai and 'Plant Cyclopeptides' published in Chemical Reviews (2006, 106(3): 840-859) by Prof. Tan Ninghua and Prof. Zhou Jun, academician of CAS. In the last year, KIB published four monographs (see Appendix 2), applied for 28 patents with 8 patents being accredited, and registered six national new plant varieties (see Appendix 3)
6. NEW AND ONGOING NATIONAL RESEARCH PROJECTS
In 2007, KIB has submitted 150 proposals for research programs at the national and provincial levels and won support for 56 projects with contract value amounting to about RMB 40 million yuan. Of all the programs, KIB presided one special program for basic scientific and technological research, participated in two 973 programs and two scientific and technological support programs with total contracted funds valuing RMB 22.8 million yuan. Other programs undertaken by KIB included 22 National Natural Science Foundation of China, one National Science Fund for Distinguished Young Scholars with contracted funds totaled RMB 8.5 million yuan, and other 28 various programs supported by the S&T Department of Yunnan and the National Development and Reform Commission with contracted funds summed RMB 8 million yuan. New and ongoing national key programs are listed in the following table.
Table 1 New and Ongoing National Key S&T Projects Undertaken in 2007
Total Fund No. Project Titles (million Period Categories yuan)
Gathering, Preservation and Sharing of Important Wild Construction of Sci. & 1 20 2006-2009 Plant Resources Tech. Resources Platform Stability Mechanism of Ecosystems of Longitudinal 2 3.8 2005-2009 973 Program Range-Gorge 2007 National Science 3 Medical Chemistry 2 2008-2011 Fund for Distinguished Young Scholars 2006 National Science 4 Plant Flora and Geography 2 2007-2010 Fund for Distinguished Young Scholars
Studies on Diversity of Higher Basidiomycetes 2005 National Science 5 and the Evolution of Representative Species in 1.6 2006-2009 Fund for Distinguished Hengduan Mountains Region Young Scholars
Secondary Development of Yunnan Special Dai 6 0.6 2007-2010 S&T Support Plan Ethno Drug, Alstonia controversa International Cooperation Research on Treatment of 7 2 2007-2010 S&T Support Plan HIV/AIDS Using TCM Construction of Library (NOVARTIS) of Natural 8 24 2007-2009 International Cooperation Products Survey and Preservation of Wild Plant Germplasm Special Foundation for 9 15 2008-2012 Resources in Special Habitats of Tibetan Plateau S&T Basic Research Evolution and Conservation of Biodiversity in Sino- 10 4.46 2007-2010 973 Program Himalayan Region
24 Annual中国科学院昆明植物研究所年报 Report 2007 2007 7. INTERNATIONAL AND REGIONAL COOPERATION
7.1 International Cooperation Projects Undertaken
7.1.1 The Fourth Scientific Survey on Plant Diversity in Hengduan Mountain Areas Completed The fourth Sino-American joint investigation on plant diversity in Hengduan Mountains Area, which is financially supported by National Natural Science Foundation of China and National Science Foundation of USA, was successfully completed. The Sino-American Joint Investigation Team for Plant Diversity in Northwest Sichuan consists of scientists from Harvard University and KIB and the investigation lasted one and a half months and the length of the journal exceeds five thousand kilometers. This investigation has finished the basic material-gathering in weakened and key areas for plant diversity in Northwest Sichuan.
7.1.2 Advances made in the Research of Natural Compounds with Novartis Inc. KIB sponsored the Annual Meeting for Cooperation Program on July 31st, 2007 with Novartis Inc., a pharmaceutical company based in Switzerland, in order to well fulfill the agreement signed between KIB and Novartis Inc. Dr. Frank Petersen and Dr. Ying Wang from Novartis Inc. attended the meeting. During the past year, KIB has established research team and gradually set up a complete system for research and administration, owing to mutual efforts poured on this cooperation program. The progress achieved will facilitate the development of the program toward a more stable and better orientation.
7.1.3 Cooperation and Development of Natural Health-care Products Conducted In collaboration with Vietnam Xieshi Biotechnological Co., Ltd., KIB carried out the program of 'Studies on Natural Food Additives and Related Health-care Products as well as Charging Commissioned Development', and set up 'Yunnan Botanical Society-Xieshi Excellent Graduates Scholarship' to award excellent incumbent graduate students.
Annual Report 2007 25 7.2 Organizations Jointly Established
7.2.1 Lijiang Alpine Botanical Garden, which is a scientific research platform jointly constructed by Royal Botanic Garden Edinburgh and Kunming Institute of Botany, together with Yunnan Academy of Agricultural Science for biodiversity conservation in Southwest China, started running formally 7.2.2 Center for Mountain Ecosystem Studies, which is jointly founded by ICRAF and KIB, plays a very important role in studies on development in Southwest China mountains areas 7.2.3 Institute of Tibetan Plateau Research at Kunming has recruited overseas scientists and established innovation research team, starting operations formally 7.2.4 The partner laboratory co-founded by the State Key Laboratory of Phytochemistry and Plant Resources in West China and the Chinese University of Hong Kong opens up formally 7.2.5 Co-founded the 'Joint Laboratory of Personal Care Products' with the world-leading cosmetics company, Mary Kay, under the provision of Cooperation Confidentiality Agreement 7.2.6 The Joint Research Laboratory of Jatropha curcas was founded by cooperation between Singapore Temasek Life Sciences Laboratory and KIB to carry out comprehensive basic researches on the biofuel plant, Jatropha curcas
7.3 International Conferences Sponsored or Co-sponsored by KIB
7.3.1 Sino-Vietnamese Bilateral Meeting on Natural Product and Chemical Medicine, held in Jan. 2007 in Kunming 7.3.2 Sino-Germany workshop on Tibetan Plateau Research, held in Apr. 2007 in Kunming 7.3.3 The first International Symposium on China Alpine Wetlands and Climate Changes, held in Jul. 2007 in Kunming 7.3.4 The fifth International Workshop of Edible Mycorrhizal Mushroom, held in Chuxiong in Aug. 2007 7.3.5 International Workshop on Protection of Traditional Knowledge, held in Kunming in Aug. 2007
26 Annual中国科学院昆明植物研究所年报 Report 2007 2007 7.4 Selected Foreign Affair Activities
In 2007, KIB has handled the formalities for 20 academic visits to foreign countries and for four special visits to China of five foreigners. The number of joint field investigations claimed is 15 and personal times of reception for visits to KIB numbered 287. Main foreign affair activities undertaken:
7.4.1 Delegation of Vietnam Academy of Sciences visited KIB to attend the Sino-Vietnamese Bilateral Meeting on Natural Product and Chemical Medicine, and signed cooperation agreement with KIB
7.4.2 Delegation of Graduate Students Education from Wisconsin University visited KIB and signed a cooperation agreement on joint education of graduate students
7.4.3 Prof. Zheng Yongqi, a pharmacologist from Yale University visited KIB
7.4.4 Delegation of Institute of Chinese Medicine, the Chinese University of Hong Kong visited KIB and signed a cooperation agreement
7.4.5 Delegation of Department of Hill Tracts, Chittagong, Bangladesh visited KIB
7.4.6 A delegation consisting of four members headed by vice director of U.S. National Science Foundation visited KIB
7.4.7 Experts from Department of Arts and Design of Rove City University held the Arts and Science Popularization Expo at KIB
7.4.8 A delegation consisting 12 members including president of Hai-O Group and Golden Hope Group of Malaysia visited KIB
7.4.9 Scientists from Research Institute of Ecological and Biological Resources of Vietnam Academy of Sciences visited KIB and carried out a 10-day cooperation program
Annual Report 2007 27 7.4.10 A delegation consisting of six members from Singapore Temasek Life Sciences Laboratory visited KIB and signed a cooperation agreement
7.4.11 A delegation consisting four members of the Preparation Office of Bonn Program of Ministry of Foreign Affairs of China visited KIB
7.4.12 A delegation consisting four members of Queen's Botanical Gardens of Thailand visited KIB
7.4.13 Students delegation consisting seven members from Keio University of Japan visited KIB
7.4.14 A delegation consisting four members headed by director of Korean Sunchon National University visited KIB and signed a cooperation agreement
7.4.15 A delegation consisting of four members headed by the director of National Institute of Biological Resources of Korea visited KIB and signed a cooperation agreement
7.4.16 A delegation consisting of three members headed by director of Korean Industry Promotion Agency visited KIB and signed a cooperation agreement
28 Annual中国科学院昆明植物研究所年报 Report 2007 2007 7.5 Cooperation Programs with Enterprises
7.5.1 Signed a cooperation agreement with Yunnan 7.5.6 Conducted the program of studies on raw Yuanyi Garden Engineering Co., Ltd., focusing on materials of Weimaining and modification of studies on grafting and propagation of camellia and quality standards commissioned by Zhejiang Huayi industrialization development of cypripedium plants. Pharmaceutical Co., Ltd. According to the agreement that will last four years, 7.5.7 Conducted the program with contracted mutual parties of the agreement will share the interest fund valuing RMB 250 thousand yuan, which is pro rata. commissioned by Jiyuan Jishi Pharmaceutical Co.,Ltd., 7.5.2 Signed the supplemental agreement with Yunnan Henan, focusing on R&D of anti-tumor drugs, total Spirin Bioengineering Co., Ltd. for further studies of diterpene extracted from Rabdosia rubenscens. Erigerontis injection on basis of previous cooperation 7.5.8 Carried out a research program with program. The company provided additional RMB two contracted fund totaled RMB 220 thousand, which is commissioned by Yunnan Jinsha River Hydropower Co., million yuan for more profound studies with a period of Ltd., focusing on influences and evaluation of flooding four years. project of Liyuan Hydropower Station Reservoir on the 7.5.3 Signed a cooperation agreement with Yuan biodiversity in Yulong Snow Mountain Natural Reserve Jinbiao Biotechnoloy Co., Ltd., which provided a fund and Harba Snow Mountain Natural Reserve. valuing RMB two million, to carry out R&D of anti- 7.5.9 Carried out a research program with depression drugs. contracted fund totaled RMB 200 thousand, which is 7.5.4 KIB signed a cooperation agreement with commissioned by Ninglang Bureau of Transportation, independent Yunna Jiyuan Biotechnolog Co., Ltd., focusing on influences and evaluation of reconstruction which provided a fund valuing RMB 80 thousand, to project of Ninglu highway on the biodiversity in Luguhu carry out breeding and improvement of taxus varieties. Lake Natural Reserve. 7.5.5 Carried out the program of scientific surveys on selected plant resources in Yulong Snow Mountain Natural Reserve with fund amounting to RMB 0.32 million yuan. The program was commissioned by Administration Commission of Yunnan provincial natural reserve, Yulong Snow Mountain Natural Reserve of Yulong County, Yunnan. 7.6 Transfer of Achievements 7.6.1 The new rhododendron cultivars, Xilinmen and Jiaoyan were sold to Yunnan Green-Land Biological Technology Co., Ltd. at price of RMB 300 thousand yuan. 7.6.2 Crude medicine of cepharanthine hydrochloride and approval document for clinical trials of cepharanthine hydrochloride injection were sold to Dali Pharmaceutical Co.,Ltd. at price of RMB six million.
7.7 KIB Shareholding Enterprises
7.7.1 Yunnan Green-Land Biological Technology Co., Ltd. Relying on its own competitiveness and great potential for future development, KIB shareholding enterprise Yunnan Green-Land Biological Technology Co., Ltd. was successfully listed in the Shenzhen Stock Exchange with approval for public offering of A-shares from China Securities Regulatory Commission. The main businesses of the Company include seedling production and sale of greening plants, as well as designing and undertaking of greening engineering projects with total 62.9373 million shares and shareholding ratio of KIB is 10.66% with market value exceeding RMB 400 million yuan. Yunnan Green-Land Biological Technology Co., Ltd. is the first KIB shareholding enterprise that has been listed in the stock market, which set an excellent paradigm for transfer and industrialization of scientific research achievements at KIB. It also provides valuable experience and reference for KIB in facilitating industrialization.
7.7.2 Yunnan BioBioPha Co.,Ltd. Due to KIB’s advantages in phytochemistry scientific research and State Key Laboratory of Phytochemistry and Plant Resources in West China, KIB successfully won private investment valuing RMB 20 million and established the Yunnan BioBioPha Co.,Ltd. with registered capital totaled RMB 23 million. Depending on technology appraised as capital stock, KIB possesses 13% of the total shares. The main businesses of the company include R&D and utilization of natural activity. The founding of Yunnan BioBioPha Co.,Ltd., which is a new trial for KIB to accelerate industrialization using technology advantages, provides an ideal platform for industrialized transfer of KIB’s research achievements.
Annual Report 2007 29 8. CONSTRUCTION OF TALENTS TEAM AND SCIENTIFIC RESEARCH PLATFORMS
8.1 Breakthrough Made in Construction of High-level Talents Team
KIB fully utilized the resources and properly selected research fields according to actual discipline structure and requirements for further development. KIB has poured strenuous efforts to create a favorable environment for talents with preferable policies and implemented the talent-recruiting strategy to welcome excellent scientists.
8.1.1 Dr. Li Weiqi was recruited into the 'Hundreds of Talents Program' of the CAS
Dr. Li Weiqi graduated from the Chemistry Department of Beijing Normal University with a bachelor’s degree in Jun. 1983, and obtained his Master Degree and Ph.D. from Department of Biochemistry of Kansas State University, USA in Dec. 2002 and Dec. 2004, respectively. His doctoral dissertation was successively published on Nature Biotechnology (impact factor = 17) and Journal of Biological Chemistry (impact factor = 6), which earned him four awards in praising his marked contribution to the fields of biochemistry, molecular biology and lipids given by the universities or academic schools in America. In 2005, Dr. Li was recruited into KIB as a 'Hundreds of Talents Program' scientist and passed the 2007 annual examination for 'Hundreds of Talents Program'. In 2007, one of his papers was online published on the Journal of Biological Chemistry and was rated as one of the outstanding scientific achievements of China Mainland and Hong Kong by the magazine of Nature China . As a co-author, Dr. Li also published another two SCI-index papers. In 2007, the research group led by Dr. Li successfully applied for two programs, one subproject of the 973 Program and one subproject for national scientific and technological basic platform with funds totaled about RMB 800 thousand. There are two graduate students and two doctoral students now working at Dr. Li’s research group.
8.1.2 Prof. Tan Ninghua Won Support of National Science Fund for Distinguished Young Scholars
Prof. Tan Ninghua graduated from Guizhou Medical College in 1984 and acquired her Master Degree and Ph.D. from China Pharmaceutical University. Upon completion of post-doctoral programs at KIB, she chose to work here and once carried out cooperation research projects in Germany (1996), the United States (1998) and Australia (2006) as a visiting scholar. She was selected to be a young and middle- aged senior scientist of Yunnan, scientist of CAS Western Light Talents Program and laureate of National Science Fund for Distinguished Young Scholars in 1997, 2004 and 2007, respectively. Prof. Tan, who currently is the vice chair of the State Key Laboratory of Phytochemistry and Plant Resources in West China, has published a total of more than 140 papers including over 60 papers in SCI-index journals such as Chemical Reviews and Organic Letters , and seven monographs. As the laureate of the first-class prize of Yunnan Natural Science Award, Prof. Tan has preside over 20 research programs and organized two international conferences. She is now an editor of Journal of Integrative Plant Biology and her research fields ranging chemistry of natural drugs, pharmacology and medicinal design, and her research interest lies in cyclopeptide.
30 Annual中国科学院昆明植物研究所年报 Report 2007 2007 8.1.3 Prof. Sun Hang Awarded 2007 State Class New Century Hundred-Thousand-Ten Thousand Talents Project Candidate
Born in Dec. 1963, Prof. Sun Hang graduated from Yunnan University in Jul. 1983 and obtained his Master's Degree and PhD from KIB in 1988 and 1994, respectively. Prof. Sun now is the Deputy Director of KIB and Secretary of KIB CPC Committee. He has received numerous awards and honors including CAS Zhu Kezhen Scientific Fieldwork Award, second-class prize of CAS Natural Science Award, etc. Scientific programs Prof. Sun has undertaken include three National Natural Science Foundation Program, one Key Program, Key International Cooperation Program, one National Science Fund for Distinguished Young Scholars Program, one key program specially supported by CAS Special Foundation, one CAS Innovation Orientation Program and one Special Program of Basic Research of Ministry of S&T. The number of papers he has published on core domestic and international journals exceeded 60. In addition, Prof. Sun has authored or co-authored six monographs.
8.1.4 Dr. Gao Lizhi, a Newly-Recruited Overseas Outstanding Talent Applied to be CAS 'Hundreds of Talents Program'
Dr. Gao Lizhi obtained Bachelor of Science from Department of Biology of Yunnan University in 1991 and PhD from CAS Institute of Botany, under direction of Prof. Hong Deyuan, a CAS academician in 1997. And under direction of Prof. Dong Yuchen, an academician of Chinese Academy of Agricultural Sciences, he completed his post-doctoral researching program in 1999. Dr. Gao was once awarded the Vavilov-Frankel prize by IPGRI affiliated to FAO in 1999. From 1999 to 2004, Dr. Gao successively carried out post-doctoral studies at Department of Biology, Washington University in St. Louis, Department of Genetics of Georgia University, Department of Ecology and Evolution Biology of Michigan State University, the Center for Human Genetics, Texas University Huston Campus. And since 2005, he worked at Huston University as an assistant professor. In 2006, Dr. Gao was recruited into KIB as 'Hundreds of Talents Program' scientist. He is presently the chair of the Center of Plant Germplasm and Genomics. Dr. Gao has made globally-recognized contributions to studies on population genetics, molecular ecology and conservation genetics of Oryza rufipogon. Through studies on genomes of model species including rice, arabidopsis thaliana, poplar, microzyme, human and mouse and using technologies of genomics and bioinformatics, Dr. Gao has carried out studies on a series of important problems of evolution biology and ecology, such as the contribution of gene duplication (including polyploid) and transposon in structure, evolution and function of plant genomics, and achieved some unique results since 2000. Dr. Gao now is dedicating his efforts to the sequencing of genomes of Oryza rufipogon and Camellia sinensis. As the first author or corresponding author, Dr. Gao has published over 40 papers on many world-leading journals such as Science. He is a peer reviewer for over 20 SCI-index academic journals.
Annual Report 2007 31 8.1.5 Four Excellent Overseas Scientists with Average Age of 33 Recruited and Entitled as Professors
Born in 1973, Dr. Hu Xiangyang graduated from Anhui University with major of Biochemistry, and acquired his Master’s Degree and Ph.D. from Shanghai Institute of Plant Physiology and Ecology through master-doctor combined program. Later on, Dr. Hu carried out postdoctoral researches at University of California (Riverside) and John Innes Center, Norwich, UK. In Jul. 2007, Dr. Hu was recruited to Institute of Tibetan Plateau Research at Kunming. He has published many papers on preeminent journals including Molecular Cell Biology, Plant Physiology, Plant Cell Physiology, Cell Research, Science in China and Chinese Science Bulletin. Dr. Hu mainly concentrates his researches on plant stress adaptation and molecular mechanism of evolution including the following aspects: 1) Screening of Arabidopsis mutants sensitive to stresses such as salt, drought, freezing and high ultraviolet radiation and cloning of important functional genes 2) Molecular mechanism of plant adaptation and evolution under extreme stresses in Qinghai-Tibetan Plateau areas, and cloning and analyzing of important functional genes 3) Accumulation of secondary products resulted from response of medical plants to stresses and expression of relative genes
Born in 1973, Dr. Guo Zhenhua graduated from Department of Biology of Liaocheng University, Shandong in 1997, and acquired her Master’s Degree and Ph.D. from KIB through master-doctor combined program in 2002. From 2002 to 2006, Dr. Guo carried out postdoctoral researches at East Carolina University, USA, focusing studies on bioinformatics and comparative genomics. Later on, Dr. Guo undertook postdoctoral studies on technologies of biochip and expression models of cellular senescence associated genes at Yale University from Mar. 2006 to Jul. 2007. In Aug. 2007, Dr. Guo was recruited in the research group for the Southwest China Germplasm Bank of Wild Species, engaging in studies on molecular systematics and molecular evolution and comparative and functional genomics. She has published over 10 papers and co-authored two monographs, among which five papers were published on mainstream journals in the field of evolution biology and relative interdisciplinary subjects such asMolecular Biology and Evolution, BMC Genomics, Molecular Phylogenetics and Evolution and Journal of Plant Research, etc. In terms of research programs undertaken, Dr. Guo once preside one National Natural Science Foundation Program and one Yunnan Natural Science Foundation Program.
Dr. Li Shenghong graduated from Department of Chemistry of Yunnan University, in 1996, and acquired his Ph.D. from the State Key Laboratory of Phytochemistry and Plant Resources in West China of KIB, where Dr. Li began his work as a research assistant. In Apr. 2003, Dr. Li was promoted to be an associate professor and carried postdoctoral studies at Chinese Medicine Institute of The Chinese University of Hong Kong from Mar. to Sep. 2004. Concentrating on studies of chemical identification of phenolic defensive components in Picea abies and of their orientation in special cells, Dr. Li carried out postdoctoral research at Max Planck Institute for Chemical Ecology, Germany from Oct. 2004 to Jan. 2008. Dr. Li is the first scientist in the world who studies the plant cellular secondary products using the combined method of laser microdissection and cryogenic NMR. Based on the research results, Dr. Li found that it’s evident that some phenolic compounds involved with plant cellular defensive mechanism.
32 Annual中国科学院昆明植物研究所年报 Report 2007 2007 He has published over 60 papers in international and domestic core journals, most of which are SCI-index ones. Dr. Li has applied for one patents and also obtained the patent approval. He has presided and completed one National Natural Science Foundation Program and one Yunnan Natural Science Foundation Program. In 2002, Dr. Li received the first-class of Yunnan Natural Science Award (the sixth participant) and was chosen to be 'Yunnan Young and Middle-aged Senior Scientist' candidate of the sixth batch in 2003. Dr. Li won the Humboldt Foundation research fellowship from 2005 to 2007, and was recruited in the State Key Laboratory of Phytochemistry and Plant Resources in West China, focusing on studies on chemical ecology of plant secondary products.
Born in 1974, Dr. Li Yan graduated from School of Life Sciences, Shandong University in 1995, and acquired her Master Degree in cell biology from Shandong University in 1998 with degree dissertation study of the anti-tumor and anti- ageing activities of components extracted from natural plants and alga. From 1999 to 2002, Dr. Li carried out studies for her Ph.D. and postdoctoral research at DKFZ, Germany. In 2001, she acquired her PhD degree from Shandong University and her dissertation mainly focused on WNT signaling pathway and the mechanism to modulate early head development and differentiation of embryo. In 2003, she began her postdoctoral training at CCHMC, USA, concentrating on the regulatory mechanism of WNT signaling during the early development of digestive system. In 2007, Dr. Li was recruited to the State Key Laboratory of Phytochemistry and Plant Resources in West China, KIB. The main tasks of her research group are screening natural products with bio-activities and conducting further mechanism studies in the field of molecular signaling pathways. The work will lead to discovering of small molecules as probes to explore further the signaling pathways closely related to human diseases and discovering medical leading compounds and/or efficient drug targets in treatment of tumor and other diseases.
Others
In 2007, KIB recruited five doctors for post-doctoral training including one foreign doctor, two senior visiting scientists, one 'Western Light' visiting scholar (Jiang Siping) and one fellow (Ni Zhen) for scientific and technological administration. Meanwhile, KIB sent a member (Yu Fuqiang) of 'Service Group of Doctors' to Bureau of Forestry of Diqing as the deputy director general. Dr. Shui Yumin obtained post-program support from the 'Western Light Program'. Six scientists from KIB won support from the 'Western Light Program' and the applications for program supporting doctors in Western China in 2006 and 2007 have been completed. Fourteen scientists from KIB won support of this program with fund totaled RMB 2.44 million yuan.
Annual Report 2007 33 8.2 Construction of Platform for Scientific Research 8.2.1 Phytochemistry Analyzing and Testing Center
The KIB Analysis and Test Center owns first-class, large- and intermediate-sized facilities in China for chemical research on natural drugs. The center has passed the Yunnan Computation Accreditation and has established the chemistry library of natural products and platform for screening drugs. The center is capable of providing 26611 maps, 127 reports of metrology accreditation every year and the annual revenue amounts to RMB 1.76 million yuan. The center strictly adheres to the tenets of 'open to the institute and the entire society, and serve the institute and the entire society', playing an active role in technological innovation, international cooperation and education & training apart from routine work. In 2007, the Center has successfully completed the tasks with high-quality services and distinguished performances.
8.2.2 Herbarium (KUN)
After reconstruction, Herbarium (KUN) now is capable of preserving over four million specimens. The number of specimens preserved at the Herbarium of lichens, large fungi, bryophytes, ferns and seed plants amounts to 1.2 million by 2007 and the data of all type specimens and 1/4 of all the specimens have been made available on the Internet. New accessions of specimens at the Herbarium was 23028 in 2007, and the reception times of visitors from home and abroad amounted to 1400. Besides, over 2000 specimens have been exchanged with other large hebaria. Furthermore, a total of 2000 specimens have been identified and 4897 specimens are collected. Besides routine job, workers in the Herbarium also apply for funds, presides programs and contributes papers. In 2007, the personnle of Herbarium has translated one monograph and published 12 papers, including five SCI-index papers and five CSCD papers.
8.2.3 The Southwest China Germplasm Bank of Wild Species
The Southwest China Germplasm Bank of Wild Species is one of the three major organizations for conservation of important plant species in the world. By the end of 2007, the total investment of the program is RMB 148 million yuan with amount of counterpart funds in position numbering RMB 141 million. Accumulated investment implemented amounted to 100.27 million and the investment for 2007 was 26.69 million. The projects for main body and infrastructural construction have passed the acceptance evaluation. The installation and testing of seed-preservation facilities of the underground warehouse (refrigeratory/drying room) have already been completed and put into use. Public bidding invitation and procurement of main facilities for studies on plant genomics and construction of DNA library has been finished and research platform for plant genomics been constructed. The testing for fire-fighting facilities and electric detection have been completed and the certificate been obtained. Acceptance examination of fire-fighting will be undertaken in near future and the totally automatic steel-structure green house is under construction. In companied with the construction the application for approvals of field gathering and specimen collecting has been completed. In 2007, the gathering of seeds, data, specimens and images of a total of 13708 accessions of wild plant species has been finished, 1200 accessions of seeds been received and exchanged. And 2326 accessions of seeds have been identified and 194 accessions of seed samples have been sent as materials and data resources for scientific studies. Through the program platform established, 34 volunteers for seed gathers were able to receive trainings and several social practices have been carried out here including practices of the Departments of Biology of Wuhan and Tsinghua Universities.
34 Annual中国科学院昆明植物研究所年报 Report 2007 2007 8.2.4 The Horticulture Center
A total of 667 additional plant taxa have been introduced by the supporting system of KIB Botanical Garden, and the seed exchange between Chinese and foreign botanical gardens has been resumed after years of intermitting. Over 40 thousand seeds from more than 50 populations of Jatropha curcas as well as 2500 living plantlets and saplings have been collected and preserved at the center. The construction of 'Ornamental Foliage and Fruit Plants Garden' occupying an area of 2.4 ha has been completed and opened to the public. The garden is consisting of nine functional sections, and some 140 thousand plants belonging to 415 taxa, 260 genera and 116 families have been planted and exhibited. The gate construction of the station, crawls and a 400 m2 greenhouse has been completed at Lijiang Alpine Botanical Garden, where precise management and maintenances of of Botanical Garden and their management has been garden of an area exceeding 400 mu was performed. well organized and initiated, and the translation of The provisions and rules have also been perfected, a famous monograph concerning plant field survey, enduring the safety and order of visits of 416 thousand 'George Forrest-Plant Hunter' has also been completed. visitors during the year. In addition, a series of science- Inddition, a total of 1039 plant labels ranked the popularization activities have been successfully held, international standard level were made and placed on such as CAS Public Science Day, National Science the plants at the Botanical Garden. Popularization Day and secretes of green leaves, etc. All activities were brought to audience of millions of thousands through coverage and reports by TV and 8.2.5 Scientific & Techological Information newspapers.The website of the Botanical Garden has Center been founded and the main plant taxa of different sections or featured gardens have being made available In 2007, the information center strengthened the for online searching by means of listing these plants planning, construction and management of websites into a specific column. The workshops on construction at different levels, successfully implementing the self- created networking information security supervision system. The networking U disk storing system worked normally and regular check up and service for computer security maintenance were carried out. The center endured the normal running of ARP system and security of the data, and successfully deployed V1.0 the searching system. The information center made huge amounts of videos and multimedia materials for Prof. Wu Zhengyi’s application for the state supreme scientific and technological award. The center as well set a service area of information resource and steady progress have been made for the journal, Acta Botanica Yunnanica. In 2007, the Botanical Society of Yunnan has raised a foundation valuing RMB 180 thousand and the running of the society is towering a correct direction. The aforementioned efforts and endeavors made by the center enormously guarantee the researching personnel using the Internet more conveniently and safely and the center provided more convenient, faster services, saving significant costs for the institute. In summary, the Center well played its role of providing support and service.
Annual Report 2007 35 9. CONSTRUCTION OF INNOVATIVE CULTURE AND MANAGEMENT SYSTEM
9.1 Infrastructure Projects during among different parties, sticking to planning and accounting principles and construction of incorruption 'Tenth-Five' and Two Major Projects culture and construction in civilization. Passed Acceptance Examination 9.2 KIB Maintained its Leading Role in Public Affairs and Propagandas in CAS Relying on various efforts and advantages of CAS members, experts and provincial and national committee of CPPCC and deputy of the People’s Congress, KIB managed to provide services and suggestions for democratic decision-making of the government, sticking to legal administration and strengthening administrative supervision, actively forwarding advice and suggestions for social, economic and S&T development of local areas. In addition, we reported honestly to CAS and government of different levels on public affairs of the CPC committee at KIB and innovations achieved. In 2007, the public affairs work in 2007 maintained a satisfying development trend Infrastructure projects during 'tenth-five' period of KIB and scored 332, which is ranked No.9 among the 142 already entered the ending stage. As an important institutions of CAS. KIB was rated as an 'Outstanding part of Knowledge Innovation Program, the program Institution' in propagandizing information about management team of infrastructure program fully implementation of CAS public affairs management respected the suggestions of varied departments, standards. Of all the information concerning public accepted consciously the supervision of the Workers’ affairs management reported by KIB in 2007, 103 Union and discipline inspection, handled the affairs pieces of information were adopted by CAS Office and strictly according to the basic procedures and strictly CAS website including 8 pieces of information further controlled the proceeding, quality and investment of the forwarded by CAS Office to CAS Special Reported projects so as to ensure the KIB infrastructure project Information, 4 pieces of information adopted by the to proceed steadily and investment to be launched Office of CPC Central Committee or Office of the State safely. On Sep. 17th, the newly-built comprehensive Council, two pieces of information included into Top building for scientific research and reconstruction Leader Reference Materials, one instruction given by project of the state key laboratory successfully passed CAS leaders, two issues of Innovation Newsletter, and the professional acceptance examination sponsored 88 pieces of information cited by CAS website. by CAS Bureau of Infrastructure Projects, symbolizing As for propagandas work, KIB as well holds a that the infrastructure projects of the second-phase leading role in CAS. By Dec. 30th, 2007, the statistical Knowledge Innovation Program in providing hardware information concerning the ranking of institutions in support for scientific research activities has been terms of news release further reinforced and recognized. The achievement of and propagandas infrastructure projects of KIB is a result of combination revealed that KIB was of full support from KIB leaders and KIB Infrastructure ranked No. 3 with total Projects Leaders’ Group, standardized operation and accumulative number strict management of the projects,collaborations of news amounting to 82 and accumulative score of 299. The General Administrative Office successfully initiated and organized the propagandas work and news covering of many important activities occurred at
36 Annual中国科学院昆明植物研究所年报 Report 2007 2007 KIB, such as project completion ceremony, application for the state supreme scientific and technological award and inception meeting for editing of Biology Volumes of the Great Encyclopedia of China. Such work greatly expanded KIB’s social influence, creating an irreplaceable image of KIB in research field of use and protection of plant resources in China and successfully popularizing the research achievements of KIB.
9.3 Effectively Implementing CAS Public Affairs Management Standards
CAS proposed and fully implemented the public affairs management As an important measure for management which is another innovation during the third-phase Knowledge important work Innovation Program of CAS, the implementation of of management CAS public affairs management standards would innovation after certainly facilitate the construction of management the deployment of system of modern institutions with more standardized ARP system, and and effective public affairs management, continually also an important making basic, strategic and forecasting contributions measure for fulfillment of 'four first-class' CAS and of great significance to national economic development for accelerating the standardized and scientific and infrastructure. management. KIB added the work of implementing the CAS public affairs management standards into the schedule of public affairs at KIB. With particular attention from KIB leaders, full support and 9.4 Outstanding Individuals and coordination among different departments, the entire Organizations Emerging Continuously work was carried out effectively and orderly. Owing to strenuous efforts, KIB even made improvements and in the Institutionalized and Innovative adjustments in responses to the advice and suggestions Culture Construction made during systematic inspection and eventually, KIB reached two CAS first-class standards in terms of Resulted from unrelenting scientific practice and security management and information propagandas, intellectual development of several generations of two CAS second-class standards in archive processing scientists, the spiritual culture of KIB can never be and filing management, respectively. KIB was as well established in short time, but involves scores of years’ rated as an 'Outstanding Institution' in propagandizing accumulation and development. Due to integral efforts information about implementation of CAS public affairs made by both the staff and graduate students, the management standards, and in assets checking. excellent tradition, will character and thought realm of KIB have been forwarded improved and reinforced. And all of us will made due contributions to construction of innovation culture of KIB. Prof. Hao Xiaojiang won the honor of 'Outstanding Individual in the Third CAS Innovation Culture Construction'. On Mar. 21st, 2007, deputy secretary of CPC Branch Committee of CAS announced the 'Resolution Concerning Awarding the Outstanding Institutions and Individuals in the Third CAS Innovation Culture Construction'. A total of 10 institutions won the honor of 'Outstanding Institution in the Third CAS Innovation Culture Construction' and 21 persons won the honor of 'Outstanding Individual in the Third CAS Innovation Culture Construction'. Encouraging by the spirit of outstanding institution and individuals, both the leaders and employees of KIB would commit to
Annual Report 2007 37 the great practice of scientific innovation and create an behavior guide lines to encourage all the workers to innovative, competitive, collaborative and harmonious fulfill the knowledge innovation goals, which would play cultural environment, making continuous contribution an positive role in terms of increasing management to construction of a innovative, ambitious and efficiency and work quality and of creating a favorable harmonious CAS. environment for scientific research and a civilized The research group of origin and evolution of alpine working environment. With the development of KIB, flora of KIB won the honor of 'Outstanding Group the Assembly will be further revised accordingly, in Innovation Culture Construction CAS Kunming toward the goal of 'first-class management'. Branch' and Prof. Hu Hong and Ms. Yin Wen won the honor of 'Outstanding Individual in Innovation Culture Construction CAS Kunming Branch. 9.6 Institute-level ARP System Successfully Upgraded and the Second- 9.5 Strengthen Regulation Construction phase Program under Preparation and Standardized Management The institute-level Academic Resource Planning (ARP) system has been successfully upgraded, providing In order to meet the high-level platform for the institute’s management requirements of 'four innovation. To date, the ARP System has already first-class' proposed by proved to be effective in management, statistical Chinese President, Hu accuracy, time inquiries, integral information and data Jintao for prospective sharing. Through continuous practice and testing, the development of CAS ultimate goal of scientific decision-making, optimum and on basis of the resources configuration, collaboration of management tenet of 'founding the and normalization of workflow and sharing of institute scientifically, information will be achieved. running it by law and KIB has carried out an investigation on general strengthening it by execution plan of ARP System the second-phase, moral virtues'. KIB has pointing out various problems existing in the current gradually established system and proposing suggestions for optimization and completed a of the system and requirement for innovation just, efficient and meticulous management system management. In addition, the investigation report that perfectly matches the operation mechanism concerning the implementation of the second-phase and management system of goals for innovation of ARP System has been compiled, contributing to the development of KIB. Based on the previous regulations, increasing completion of ARP System. the General Administrative Office completed the Some of the problems identified about the compilation of 'Document Assembly of Regulations ARP system have already been resolved through of KIB (volume A)' (hereinafter abbreviated as the deployment and implementation of upgrade of Assembly), through abolishing, modifications and ARP System V1.1 version. On basis of the mature supplementations. experience of the first-phase, special efforts would The Assembly consists of 12 parts, namely, be concentrated on reinforcing collaborations and public affairs management, organization and structure, scientific research management, personal affairs education management, talents cultivation, information popularization and management, archives management, infrastructure and real estate management, finance and capital management, logistics management, securing and safeguard management and department management. The Assembly main contains 127 effective regulations prescribed by different departments from 1996 to 2007. The Assembly advocates the management thoughts of hierarchical management, fair and open, realistic and innovative with characteristics of guidance, standardization and feasibility. The Assembly is an important guarantee for law-based management, and
38 Annual中国科学院昆明植物研究所年报 Report 2007 2007 interactions among different departments, on combination of practice and application and on training, during the execution of the second-phase ARP System.
9.7 Acceptation Examination of First- Stage Archive Collection to CAS Successfully Completed
Archives collection is a complicated, integral project for every institution and KIB, as an important constitutional part of CAS, is obliged to carry out the work of archives collecting according to the Archives Law, guaranteeing the integrity and accuracy of historic recordings of KIB as well as CAS. Archives of CAS is the permanent base preserving materials of real history and development procedures of CAS as well as its affiliated institutions, and the center of providing useful information for all circles of the th society with diversified purposes. In order to build up of CAS, was held on Apr. 10 , 2007. During the a scientific preservation system of Archives of CAS, it’s examination, the scopes of archives collection, quality the prerequisite to collect various archives with historic for archival description and compilation of retrieval proof function and scientific research value from all tools for various archives before 1980 collected at the institutions with their own archives to assure KIB Archives were carefully inspected. The evaluation of sufficient archives, accumulation of information group deemed that the archives accorded to relative resources and availability of useful information of the standards and requirements and can be preserved at Archives of CAS. It’s also the obligatory task for every the Archives of CAS. institution affiliated to CAS. The acceptance examination of KIB’s archives collection, which was sponsored by an evaluation group consisting four members including Director of Achieves
Annual Report 2007 39 APPENDIX 1: STAFF AND STUDENTS
Director: LI De-Zhu CAS Key Laboratory of Biodiversity and Biogeography Deputy Directors: Director: SUN Hang SUN Hang (Concurrent post) YANG Yong-Ping LIU Ji-Kai Executive Director: GAN Fan-Yuan ZHOU Zhe-Kun Director Emeritus: Innovation Base Consultant: WU Zheng-Yi WU Zheng-Yi YANG Yun-Shan (Secretary to Academicians) General Administrative Office GAN Fan-Yuan (Head, Concurrent post) LI De-Zhu’s Group: QIAN Jie (Deputy Head) LI De-Zhu XIONG De-Hua WANG Hong ZHAO Ji-Dong YANG Jun-Bo TIAN Zhi-Duan XUE Chun-Ying HUANG Lu-Lu GAO Lian-Ming WU Yan LU Jin-Mei YANG Song YU Wen-Bin (since July 2007)
Division of Human Resources, LIU Pei-Gui’s Group: CPC & Education Affairs LIU Pei-Gui WU Shu-Guang (Head) ZHANG Chang-Qin LI Ying WANG Xiang-Hua ZENG Yan-Mei YU Fu-Qiang YIN Wen ZHANG Jing-Li (since in July 2007) LI Jiang-Wei WU Shao-Bo SUN Hang’s Group: PU Ying-Dong SUN Hang HE Hai-yan NIE Ze-Long HUA Hong-Ying Yue Ji-Pei ZHA Hong-Guang (since September 2007) Division of Science and Development CHEN Lin-Yang (since October 2007) WANG Yu-Hua (Head) LI Zhi-Jian YANG Zhu-Liang’s Group: MA Xiao-Qing YANG Zhu-Liang YUE Yuan-Zheng ZHANG Li-Fang LI Xiao-Xian WANG Lan TIAN Ning ZHANG Ping NI Jing-Yun ZHOU Zhe-Kun’s Group: Division of Assets and Finance Management ZHOU Zhe-Kun (combined with Division of Science and Development to be Division CHEN Shao-Tian of Science, Development, Assets and Finance Management in July JI Yun-Heng 2007, with WANG Yu-Wang as the Division Head) CHEN Wen-Yun ZHANG Ying-Jue (Acting Head, till June 2007) YANG Ge-Lan The Herbarium (KUN) HAN Min PENG Hua (Curator) WANG Ying LEI Li-Gong XUAN Yu WANG Li-Song DUAN Jun-Hong LI Xue-Dong GU Shuang-Hua WANG Jing-Hua HU Bin ZHANG Yan WANG Lin Sci. & Tech. Information Center XIANG Jian-Ying ZHOU Bing (Chief Executive) LIU En-De LIU Ai-Qin WU Xi-Lin (retired November 2007) ZHOU Yi-Lan ZHOU Hong-Xia (till May 2007) DU Ning HE Yan-Biao Other Members: HE Yun-Cheng SHUI Yu-Min YANG Qian (till May 2007) YANG Shi-Xiong LI Tuo-Jing (Since in July 2007) HU Yun-Qian CHEN Wen-Hong Biogeography and Ecology Department YANG Xue Head: ZHOU Zhe-Kun CAI Jie Deputy Head: PENG Hua
40 Annual中国科学院昆明植物研究所年报 Report 2007 2007 WEN Ning YUAN Li WEN Yi-Lin YANG Qing-Song LIU Meng-Qi Master’s Students (37): XING Yao-Wu FANG Wei PU Chun-Xia REN Zong-Xin LIU Zhen-Wen LIU Jie XIA Ke ZHANG Yu-Xiao GAO Qian AI Hong-Lian LI Yan-Chun ZHANG Shu XIANG Chun-Lei ZHOU Wei QIAO Qin DENG Xiao-Juan TIAN Wei TIAN Xiao-Fei ZHOU Jing MA Yong-Peng ZHANG Yu-Xiao SHEN Min LIU Yan-Chun NIU Yang YANG Ying YUE Liang-Liang ZHU Wei-Dong FENG Bang HE Jun SU Tao ZHANG De-Quan YU Wen-Tao TANG Li-Ping XU Jin DONG Zhao-Hui Laboratory of Ethnobotany YANG Jie Head: ZHANG Rong-Mei YANG Yong-Ping (Concurrent Post) ZHAO Hou-Tao XU Ping-Zhen YANG Yong-Ping’s Group: WU Yan-Min YANG Yong-Ping MA Peng-Fei FU Yao HUANG Yong-Jiang LI Xiao-Li DONG Hong-Jin ZHANG Yun-Jie LONG Chun-Lin’s Group: HUANG Pan-Hui LONG Chun-Lin JIANG Wei WANG Yue-Hu ZHAO Dong-Wei HUANG Yuan SHI Xiao-Fei LUO Ji-Feng DU Xi-Hui LIU Yi-Tao ZHAI Yan-Hong Hiromichi YOSHINO XIE Xue-Dan LI Rong WANG Nian LIU Yuan YIN Zhi-Jian XI Xue XU Jian-Chu’s Group: XU Jian-Chu Ph.D. Students (44): YANG Xue-Fei QIAN Zi-Gang GAO Feng ZHANG Xue-Mei LI Qiao-Hong WANG Qun GAO Fu ZHANG Shu-Dong YANG Jian-Kun ZENG Chun-Xia LI Hai-Tao LI Zhong-Rong LU Lu Other members: WEI Zhi-Dan DAO Zhi-Ling XU Hong WANG Kang-Lin DONG Li-Na YANG Li-Xin WU Shun-Yu YANG Zhi-Wei LI Su-Mei ZHANG Guo-Xue WEI Hai-Lei WANG Jie-Ru WU Zhi-Kun XIE Hong-Yan GAO Ze-Rui LI Dong-Sheng SUN Bao-Ling ZHANG Da-Cai Master’s Students(18): TU Tie-Yao FAN Deng-Mei ZHANG Yong-Hong ZHAO Fang ZHANG Jian-Wen LI Yang CHEN Gao YI Jin YANG Yang WANG Xi ZHANG Ti-Cao LI Xin-Hui GE Zai-Wei LI Mao-Lin
Annual Report 2007 41 WANG Yun LI Yan-Mei ZHOU Lv-Liu DI Ying-Hong WANG Dan-Dan NI Wei GUO Jing-Qi LIU Hai-Yang LI Li-Ling LIU Yun-Long LIU Ji-Kai’s Group: LANG Rong LIU Ji-Kai ZHUANG Hui-Fu DING Zhi-Hui TANG Gui-Hua LI Bo ZHAO Yan-LI DONG Ze-Jun WANG Xue-Qin XU Di (Senior visiting scholar) ZHANG Yi(Secretary) Ph.D. Students(11): HAN Chun-Yan LUO Shi-De’s Group: LI Ya-Li LUO Shi-De HU Guang-Wan WANG Yi-Fen TANG An-Jun JU Peng ZHANG Xue-Mei MA Xing LUO Xiao-Dong’s Group: LI Zhuo-Qing LUO Xiao-Dong YU Hai-Ying DU Zhi-Zhi LONG Bo CAI Xiang-Hai YANG Chun-Yan LIU Wen-Jiang QIU Ming-Hua’s Group: QIU Ming-Hua LI Zhong-Rong State Key Laboratory of Phytochemistry and ZHOU Lin Plant Resources in West China HE Chun-Lin CHEN Jian-Chao Director: ZHANG Xian-Min LIU Ji-Kai (Concurrent Post) SHEN Yue-Mao’s Group: Deputy Directors: SHEN Yue-Mao TAN Ning-Hua ZENG Ying ZHAO Qin-Shi ZHAO Pei-Ji XIE Yong Phytochemistry Analysis and Testing Center MA Juan LIANG Hui-Ling (Executive chief) HE Yi-Neng SUN Han-Dong’s Group: WU Yu SUN Han-Dong YU Zhen XIAO Wei-Lie QU Yan LI Rong-Tao PU Jian-Xin Secretary: LIN Xian TAN Ning-Hua's Group: LI Lin TAN Ning-Hua XIONG Jiang Innovation Base Consultant: ZHANG Yu-Mei ZHOU Jun JIA Rui-Rui (until July 2007) LIU Yu-Qing(Secretary) HAN Hong-Jin JI Chang-Jiu CHEN Ji-Jun’s Group: ZHU Mei-ju CHEN Ji-Jun JIANG Li-Hua (until Sep. 2007) LIU Xi-Kui Pan Xu-Lin ZHAO You-Xing ZHANG Xue-Mei ZHANG Ying-Jun’s Group: MA Yun-Bao ZHANG Ying-Jun JIANG Zhi-Yong CHEN Ke-Ke LUO Jie WANG Dong ZHU Hong-Tao CHENG Yong-Xian’s Group: YANG Chong-Ren(until March 2007) CHENG Yong-Xian ZHANG Xiang-Lan LV Qing XU Min
HAO Xiao-Jiang’s Group: ZHAO Qin-Shi’s Group: HAO Xiao-Jiang ZHAO Qin-Shi HE Hong-Ping CHENG Xiao LI Shun-Ping
42 Annual中国科学院昆明植物研究所年报 Report 2007 2007 XU Gang CHEN Gui-Jv PENG Li-Yan DENG Ya-Ni ZHAO Yu CAO Jin-Xin LUO Cheng(Overseas senior visiting scientist) HUANG Sheng-Zhuo WANG Wei-Qing ZHU Hua-Jie’s Group: ZHANG Xiang-Yun ZHU Hua-Jie YANG Ting-Quan REN Jie WANG Hong-Lin JIANG Si-Ping(Western Light visiting scholar) ZENG Lin-Hong LIU Lin-Li LI Yan’s Group: DENG Xu LI Yan WANG Peng-Cheng WANG Yuan-Yuan XIAO Xiao LI Da-Shan Other Members: HAN Jing ZHOU Qian-Lan NING Jing LIU Xiao-Bing SONG Wei-Wu TAO Shi-Cong NIU Yun XU Gui-Lun WANG Cui-Fang YU Dao-You GAO Juan WANG Bo CHEN Jin-Xiong HONG Xin ZHOU Lei LI Sheng-Hong LI Hai-Zhou Ph.D. Students (52): HU Jiang-Miao CHENG Bi ZHANG Quan Master’s Students (62): LIU Ji-Feng ZHANG Nen-Lin WANG Hao-Xin WANG En-Jun GAO Zhu-Lin LIU Wen-Feng FANG Xin LIU Jian-Jun TAN Cheng-Jian GENG Chang-An MA Xiao-Xia WANG Hai-Bo TAN Qin-Gang MEI Ren-Qiang ZHANG Zhen ZHAO Jun ZHANG Qiang TONG Xiao-Gang FANG Li-Zhen GAO Suo YANG Wan-Qiu LIU Xiang-Dong YI Ping ZHANG Yu GENG Zhao-Liang CHEN Jia LI Chun-Shun ZHU Feng KANG Qian-Jin LI Shi-Fei YUAN Lin JIANG Meng-Yuan LEI Chun ZHOU Zhong-Yu LIU Jing-Ping ZHANG Lin ZHAO Yong FANG Sheng-Tao YANG Li-Bin FENG Tao GAO Xue-Mei LIU Ya-Ping TU Lin ZHANG Rong-Ting LI Xiao-Nian DU Guo-Shun LUO Xiao NIAN Yin CHEN Xuan-Qin CHENG Bao-Hui HE Fei YAN Yu-Xin TANG Jun ZHANG Xu-Dong HUANG Huo-Qiang WEI Guo-Zhu XU Jun-JV LI Jun-Lin NIU Dong-Ling FAN Jun-Ting WANG Wei YAN He LIAO Tou-Gen GAO Da-Fang JIANG Jv-Xing LIAO Peng-Ying KONG Ling-Chuan LIU Qiang LU Lu TIAN Li-Wen YANG Xiao-Long ZHANG Peng-Tao LI Liang-Bo HE Jun XU Wen-Yan GUO Na CHENG Zhong-Quan LI Ming-Ming PAN Zheng-Hong WANG Zi-Juan YAN Xiao-Hui
Annual Report 2007 43 LIU Rong GU Zhi-Jian’s Group: HU Jiang GU Zhi-Jian SHEN Yong YANG Jian-Hong HU Hong’s Group: ZHANG Hai-Bo HU Hong HE Wen-Jun ZHANG Shi-Bao SUN Yun YAN Ning WANG Kou WANG Hua ZUO Ai-Xue LI Shu-Yun LUO Gui-FEN Botanic Garden HUANG Jia-Lin Director: GUO Rui-Xian LI De-Zhu (Concurrent Post) HU Shi-Jun NI Zhen Executive Director: SUN Wei-Bang LI Wei-Qi ’s Group: LI Wei-Qi Deputy Director: TIAN Bo LI Wei-Qi WANG Rong ZHANG Fu-Juan Horticulture Center (supporting system): LI He SUN Wei-Bang (executive chief) XIE Li-Shan SUN Wei-Bang’s Group: WANG Zhong-Lang SUN Wei-Bang FENG Bao-Jun ZHOU Yuan KONG Fan-Cai YIN Qin Master’s Students(28): YU Hong-Yuan JI Li YUAN Hui-Kun ZHAO Xing-Feng XU Kun TANG Ling LI Xing-Gui WANG Xiang MAO He-Li ZHANG Le ZHANG Cheng-Min ZHAN Qing-Qing PI Wen-Lin WANG Jin-Feng LV Yuan-Lin ZHAO Yu-Juan ZHU Zhou JI Hui SHEN Yun-Guang REN Yong-Quan XIE Jian HU Xiao-Jian KONG Xian-Feng XUE Rui-Juan KUANG Jian YU Xiao-Qin WANG Shi-Qiong LEI Ming ZHANG Tao PI Qiu-Xia LU Ren-Fu ZHENG Guo-Wei LI Cong-Ren JIA Yan-Xia LI Yue-Ming WANG Rui-Ping CHEN Yu LI Li-Xia LI Yun CAI Yan-Fei ZHANG Yun-Chun AI Juan LI Ping-Hua PAN Rui YU Jiao-Jun GONG Xun’s Group: MOU Zong-Min GONG Xun YANG Hui ZHANG Zhao-Yang LI Yan PAN Yue-Zhi YU Xiao-Mei YANG Zhi-Yun YANG Li-Hua ZHANG Guo-Li Ph.D. Students(13): GUAN Kai-Yun’s Group: YANG Yao-Wen GUAN Kai-Yun LI Ai-Rong LI Hong-Zhe MA Hong LI Jing-Xiu GUAN Zhi-Jie LU Yuan-Xue LIU Li-Qin HE Zhong-Jun JIANG Nan YANG Yong-Hong WU Jiang-Chong CHEN Jing CHANG Wei LI Ai-Rong YU Bu-Zhu ZHENG Yan-Ling
44 Annual中国科学院昆明植物研究所年报 Report 2007 2007 WANG Zi-Juan WANG Kun-Sheng Yang Jing ZHAO Feng-Lan CHEN Hong-Ying DONG Hai-Jun ZHOU Jia-Xing Germplasm Bank of Wild Species in Southwest China FAN Xi-Kai FU Bao-Chong Administration Office: HU Zhao-Chang LI De-Zhu HUANG Li GAN Fan-Yuan JIAO Yun-Ting LONG Chun-Lin LI Hai-Yan YANG Xiang-Yun LI Ping-Lan ZHANG Ying-Jue LI Ping-Yi YANG Zhi-Hua(until May 2007) LI Ying-Hui HE Wei QIN Guo-Fu ZOU Jun-Wu WANG Ya-Lin SHI Zhang-Fu(until March 2007) YANG Yong-Rui YE Shi-Qing (until November 2007) Supporting System: ZHONG Shun-Rong YANG Xiang-Yun(executive chief) BAI Bo ZHANG Ting DU Yan LI Ai-Hua Botanical Society of Yunnan GUO Yun-Gang Exclusive personnel: ZHAO Jun-Fen GAO Li-Zhi’s Group: LIN Qin GAO Li-Zhi PENG Sheng Center for Mountain Ecosystem Studies JIAO Jun-Ying Director: YANG Li-Li XU Jian-Chu XU Ping-Zhen ZHAO You-Jie Members: CHEN Hua-Fang YI Ting-Shuang’s Group: YAN Mei YI Ting-Shuang ZHANG Yi-Fei YANG Yang SU Yu-Fang Timm Tennigkeit Other Members: LI Zheng-Li HE Jun GUO Zhen-Hua HU Xin-Ping LI Hong-Tao CHEN Dong MU Zhi-Lin Master’s Students(4): LIU Yang MENG Jing KIB Academic Committee and Academic Committees HU Na of State and CAS Key Laboratories FAN Ya-Yu KIB Academic Committee Chairman: Ph.D. Student(1): SUN Han-Dong LIN Li-Zhen Members: Institute of Tibetan Plateau Research at Kunming, CAS CHEN Jin(Xishuangbanna Tropical Botanical Garden, CAS) GONG Xun Director: GUAN Kai-Yun YANG Yong-Ping (Concurrent Post) HAO Xiao-Jiang HU Hong Members: LI De-Zhu HAN Xi LI Wei-Qi DUAN Yuan-Wen LIU Ji-Kai CHEN Jia-Hui LIU Pei-Gui MENG Ying LONG Chun-Lin HU Xiang-Yang PENG Hua QIU Ming-Hua Logistics Center SUN Hang Manager: TAN Ning-Hua YI Yong-Sheng XU Jian-Chu YANG Yong-Ping Members: YANG Zhu-Liang SONG Wei-Kui ZHANG Chang-Qin CAi Ming ZHANG Ke-Qin(Yunnan University)
Annual Report 2007 45 ZHANG Ya-Ping(Kunming Institute of Zoology, CAS) Honorary Posts: ZHANG Zhuang-Xin(CAS Kunming Branch) Honorary Chair of the Academic Committee of CAS Key ZHOU Zhe-Kun Laboratory of Biodiversity and Biogeography: ZHU Hua-Jie Peter Raven (Missouri Botanical Garden, Foreign Member of ZHU You-Yong(Yunnan Agricultural University) CAS) Academic Committee for State Key Laboratory of Phytochemistry and Honorary Professors: Plant Resources in West China Stephen Blackmore (Royal Botanic Garden Edinburgh) Chairman of Academic Committee: Nam-Hai Chua (Rockefeller University) HAO Xiao-Jiang Antony Galsworthy (former British ambassador to P. R. Vice Chairman of Academic Committee: China) SUN Han-Dong Jun Wen (Smithsonian Institution) CHEN Xiao-Ya(Shanghai Institutes for Biological Sciences, CAS) Honorary Director of Horticulture: David Paterson (Royal Botanic Garden Edinburgh) Committee: PEI Gang (Shanghai Institutes for Biological Sciences, CAS) DENG Zi-Xin (Shanghai Jiaotong University) TAN Ren-Xiang (Nanjing University) TU Yong-Qiang (Lanzhou University) ZHANG Hong-Bin (Yunnan University) DU Guan-Hua (Institute of Materia Medica, Chinese Academy of Medical Sciences) Ding Jian (Shanghai Institute of Materia Medica, CAS) JIANG Hua-Liang (Shanghai Institute of Materia Medica, CAS) MA Da-Wei (The Shanghai Institute of Organic Chemistry, CAS) LI De-Zhu LIU Ji-Kai TAN Ning-Hua
Advisors to the Academic Committee: ZHOU Jun YU De-Quan (Institute of Materia Medica, Chinese Academy of Medical Sciences) YAO Xin-Sheng (Shenyang Pharmaceutical University) HONG De-Yuang (Institute of Botany, CAS) LIN Guo-Qiang (The Shanghai Institute of Organic Chemistry, CAS)
Academic Committee for CAS Key Laboratory of Biodiversity and Biogeography Chairman: CHEN Yi-Yu (National Natural Science Foundation of China)
Vice Chairman: LI De-Zhu
Members: ZHANG Ya-Ping (Kunming Institute of Zoology, CAS) GU Hong-Ya (College of Life Sciences of Peking University) SHI Su-Hua (Zhongshan University) GE Song (Institute of Botany, CAS) ZHANG Ke-Qin (Yunnan University) SUN Ge (Jilin University) YANG Yu-Ming (Southwest Forestry College) Li Wen-Hua (Institute of Geography and Natural Resources, CAS) SUN Hang ZHOU Zhe-Kun PENG Hua CHEN Jin (Xishuangbanna Tropical Botanical Garden, CAS) WEN Jun (Smithsonian Institution)
46 Annual中国科学院昆明植物研究所年报 Report 2007 2007 APPENDIX 2: LIST OF PUBLICATIONS
Articles cited by SCI with KIB Staff as first Author
1. Cai, X. H., Z. Z. Du, et al. (2007).'Tirucallane triterpenoid Saponins from Munronia delavayi Franch.'Helvetica Chimica Acta 90(10):1980-1986.
2. Cai, X. H., Z. Z. Du, et al. (2007). 'Unique monoterpenoid indole alkaloids from Alstonia scholaris .' Organic Letters 9(9): 1817-1820.
3. Cai, X. H. and X. D. Luo (2007). 'Alkaloids from Stemona mairei.' Planta Medica 73(2): 170-173.
4. Cai, X. H. and X. D. Luo (2007). 'A new tetranortriterpenoid from Munronia delavayi .' Chinese Journal of Chemistry 25(7): 986-988.
5. Chen, G., W. B. Sun, et al. (2007). 'Karyomorphology of the endangered Trigonobalanus doichangensis (A. Camus) Forman (Fagaceae) and its taxonomic and biogeographical implications.' Botanical Journal of the Linnean Society 154(3): 321-330.
6. Chen, G., W. B. Sun, et al. (2007). 'Ploidy variation in Buddleja L. (Buddlejaceae) in the Sino- Himalayan region and its biogeographical implications.' Botanical Journal of the Linnean Society 154(3): 305-312. 7. Chen, J. C., Z. Q. Zhang, et al. (2007). 'Chemical constituents from the tubers of Hemsleya delavayi .' Acta Chimica Sinica 65(16): 1679-1684.
8. Chen, W. H., Y. M. Shui, et al. (2007). 'Additional notes on Melastomataceae of China.' Acta Phytotaxonomica Sinica 45(4): 587-592.
9. Cheng, P., Y. B. Ma, et al. (2007). 'Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida .' Bioorganic & Medicinal Chemistry Letters 17(19): 5316-5320.
10. Chu, H. B., N. H. Tan, et al. (2007). 'Chemical constituents from Pedicularis rex CB Clarke.' Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 62(11): 1465-1470.
11. Dao, Z. L., S. T. Chen, et al. (2007). 'Typhonium baoshanense Z. L. Dao & H. Li, a new species of Araceae from western Yunnan, China.' Acta Phytotaxonomica Sinica 45(2): 234-238.
12. Deng, C., L., Q.- G., Ren, Y., et al. (2007). 'A Comprehensive Theoretical Study on the Hydrolysis of Carbonyl Sulfide in the Neutral Water.' Journal of Computer Chemistry. 29:467.
13. Deng, Y. F. (2007). 'Validation of the name Strobilanthes sarcorrhiza (Acanthaceae).' Novon 17(2): 154-155.
14. Di, Y. T., H. P. He, et al. (2007). 'Trijugin-type limonoids from the leaves of Cipadessa cinerascens .' Journal of Natural Products 70(8): 1352-1355.
Annual Report 2007 47 15. Di, Y. T., H. P. He, et al. (2007). 'Isolation, X-ray crystallography, and computational studies of calydaphninone, a new alkaloid from Daphniphyllum calycillum .' Organic Letters 9(7): 1355-1358. 16. Fang, L. Q., Y. Z. Pan, et al. (2007). 'A karyomorphological study in the monotypic genus Lamiophlomis and five species inPhlomis (Lamiaceae).' Acta Phytotaxonomica Sinica 45(5): 627- 632.
17. Gao, L. M., M. Möller, et al. (2007). 'High variation and strong phylogeographic pattern among cpDNA haplotypes in Taxus wallichiana (Taxaceae) in China and North Vietnam.' Molecular Ecology 16(22): 4684-4698.
18. Gao, S., H. Y. Liu, et al. (2007). 'Lathyranone A: A diterpenoid possessing an unprecedented skeleton from Euphorbia lathyris .' Organic Letters 9(17): 3453-3455.
19. Gu, Q., R. R. Wang, et al. (2007). 'A new benzofuranone and anti-HIV constituents from the stems of Rhus chinensis .' Planta Medica 73(3): 279-282.
20. He, J., H. Wang, et al. (2007). 'Genetic diversity of Paris polyphylla var. yunnanensis , a traditional chinese medicinal herb, detected by ISSR markers.' Planta Medica 73(12): 1316-1321.
21. Hu G.W., C.L., Long, et al. (2007). 'Utricularia mangshanensis (Lentibulariaceae), a new species from Hunan, China.' Annales Botanici Fennici 44 (5): 389-392.
22. Hua, Y., C. X. Chen, et al. (2007). 'Two new xanthones from Polygala crotalarioides .' Journal of Asian Natural Products Research 9(3): 273-275.
23. Hua, Y., H. Y. Liu, et al. (2007). 'New eudesmane and cadalane sesquiterpenes from Parepigynum funingense .' Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 62(2): 272-274.
24. Hua, Y., J. Ren, et al. (2007). 'Determinations of the configuration of C-20 in derivatives of adynerin using DFT/HF methods.' Chemical Research in Chinese Universities 23(5): 592-597.
25. Hua, Y., J. Zhou, et al. (2007). 'A new eudesmane sesquiterpene glycoside from Parepigynum funingense .' Chinese Chemical Letters 18(1): 73-75.
26. Huang, J. and C. L. Long (2007). 'Coptis teeta-based agroforestry system and its conservation potential: A case study from northwest Yunnan.' Ambio 36(4): 343-349.
27. Huang, S. X., R. T. Li, et al. (2007). 'Isolation and characterization of biogenetically related highly oxygenated nortriterpenoids from Schisandra chinensis .' Organic Letters 9(11): 2079-2082.
28. Huang, S. X., J. X. Pu, et al. (2007). 'ent-Abietane diterpenoids from Isodon rubescens var. rubescens .' Phytochemistry 68(5): 616-622.
29. Huang, S. X., J. Yang, et al. (2007). 'Structural characterization of schintrilactone, a new class of nortriterpenoids from Schisandra chinensis .' Organic Letters 9(21): 4175-4178.
48 Annual中国科学院昆明植物研究所年报 Report 2007 2007 30. Huang, S. X., L. B. Yang, et al. (2007). 'Wuweizidilactones A-F: Novel highly oxygenated nortriterpenoids with unusual skeletons isolated from Schisandra chinensis .' Chemistry-a European Journal 13(17): 4816-4822.
31. Huang, S. X., Y. Zhou, et al. (2007). 'Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus .' Journal of Natural Products 70(6): 1053-1055.
32. Huang, H. Q., X. L. Pan, et al. (2007). '3D-QSAR study of sulfonamide inhibitors of human carbonic anhydrase II.' European Journal of Medicinal Chemistry 42(3): 365-372.
33. Ji, Y. H., Z. K. ZHOU, et al. (2007). 'Four new synonyms in the genus Paris (Trilliaceae).' Acta Phytotaxonomica Sinica. 45(3):388-390.
34. Jia, A. Q., N. H. Tan, et al. (2007). 'New cyclopeptides in Arenaria oreophila (Caryophyllaceae).' Journal of Asian Natural Products Research 9(6): 569-574.
35. Jia, A. Q., N. H. Tan, et al. (2007). 'Cyclopeptides from Sagina japonica (Caryophyllaceae).' Chemistry & Biodiversity 4(2): 241-247.
36. Jiang, Z. Y., X. M. Zhang, et al. (2007). 'Two new sesquiterpenes from Alisma orientalis .' Chemical & Pharmaceutical Bulletin 55(6): 905-907.
37. Jin, X. H., T. Zhang, et al. (2007). 'Cytological studies on the genus Holcoglossum (Orchidaceae).' Botanical Journal of the Linnean Society 154(2): 283-288.
38. Ju, P., Y. F. Wang, et al. (2007). 'A new ellagitannin from Cleidion bracteosum .' Chinese Chemical Letters 18(3): 291-292.
39. Kong, N. C., H. P. He, et al. (2007). 'Two new iridoid alkaloids, daphmacropodosidines A and B, from Daphniphyllum macropodum .' Helvetica Chimica Acta 90(5): 972-976.
40. Kong, N. C., H. P. He, et al. (2007). 'Daphnimacropodines A-D, alkaloids from Daphniphyllum macropodum .' Journal of Natural Products 70(8): 1348-1351.
41. Lei, C., S. X. Huang, et al. (2007). 'Four new schisanartane-type nortriterpenoids from Schisandra propinqua var. propinqua .' Helvetica Chimica Acta 90(7): 1399-1405.
42. Lei C., S. X. Huang, et al. (2007). 'Lignans from Schisandra propinqua var. propinqua .' Chemical & Pharmaceutical Bulletin 55 (8): 1281-1283.
43. Li, A. R. and K. Y. Guan (2007). 'Mycorrhizal and dark septate endophytic fungi of Pedicularis species from northwest of Yunnan Province, China.' Mycorrhiza 17(2): 103-109.
44. Li, C. S., Y. T. Di, et al. (2007). 'Daphlongeranines A and B, two novel alkaloids possessing unprecedented skeletons from Daphniphyllum longeracemosum .' Organic Letters 9(13): 2509-2512.
45. Li, C. S., H. P. He, et al. (2007). 'Daphlongeramine A, novel Daphniphyllum alkaloid from Daphniphyllum longeracemosum .' Tetrahedron Letters 48(15): 2737-2740.
Annual Report 2007 49 46. Li, H. M. and Z. K. Zhou (2007). 'Fossil nothofagaceous leaves from the Eocene of western Antarctica and their bearing on the origin, dispersal and systematics of Nothofagus .' Science in China Series D-Earth Sciences 50(10): 1525-1535.
47. Li, L. C., J. Ren, et al. (2007). 'A novel direct conversion of primary amides to their corresponding methyl esters.' European Journal of Organic Chemistry(6): 1026-1030.
48. Li, L. M., G. Y. Li, et al. (2007). 'Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus .' Tetrahedron Letters 48(52): 9100-9103.
49. Li, L. M., Z. Y. Weng, et al. (2007). 'Cytotoxic ent-kauranoids from the Medicinal Plant Isodon xerophilus .' Journal of Natural Products 70(8): 1295-1301.
50. Li, N., K. J. Wang, et al. (2007). 'Phenolic compounds from the rhizomes of Gastrodia elata .' Journal of Asian Natural Products Research 9(4): 373-377.
51. Li, W. H., X. M. Zhang, et al. (2007). 'A new anti-HIV lupane acid from Gleditsia sinensis Lam.' Journal of Asian Natural Products Research 9(6): 551-555.
52. Li, X., J. X. Pu, et al. (2007). 'Three new ent-kauranoids from Isodon phyllostachys .' Heterocycles 71(11): 2441-2447.
53. Li, X. L., L. M. Yang, et al. (2007). 'Tetranorclerodanes and clerodane-type diterpene glycosides from Dicranopteris dichotoma .' Journal of Natural Products 70(2): 265-268.
54. Li, X. X. and Z. K. Zhou (2007). 'The higher-level phylogeny of monocots based on matK, rbcL and 18S rDNA sequences.' Acta Phytotaxonomica Sinica 45(2): 113-133.
55. Li, Y. C. (2007). 'Two noteworthy boletes from China.' Mycotaxon 101: 223-228.
56. Li, Y. M., L. H. Wang, et al. (2007). 'Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses.' Proceedings of the National Academy of Sciences of the United States of America 104(19): 8083-8088.
57. Liang, H. X., F. K. Bao, et al. (2007). 'Antibacterial thymol derivatives isolated from Centipeda minima .' Molecules 12(8): 1606-1613.
58. Liang, H. X., F. K. Bao, et al. (2007). 'Two new antibacterial sesquiterpenoids from Centipeda minima .' Chemistry & Biodiversity 4(12): 2810-2816.
59. Liu, D. Z., F. Wang, et al. (2007). 'A new cadinane sesquiterpene with significant anti-HIV-1 activity from the cultures of the basidiomycete Tyromyces chioneus .' Journal of Antibiotics 60(5): 332-334.
60. Liu D.Z., F. Wang, et al. (2007). 'Sesquiterpenes from cultures of the basidiomycete Conocybe siliginea .' Journal of Natural Products 70(9): 1503-1506.
50 Annual中国科学院昆明植物研究所年报 Report 2007 2007 61. Liu, H. Y., S. Gao, et al. (2007). 'A novel atisane diterpenoid from Spiraea japonica var. acuta .' Helvetica Chimica Acta 90(7): 1386-1390.
62. Liu, P. G. and J. Chen (2007). 'Tuber latisporum sp. nov. and related taxa, based on morphology and DNA sequence data.' Mycologia 99(3):465-481.
63. Liu, J. F., Z. Y. Jiang, et al. (2007). 'Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of Isatis indigotica .' Organic Letters 9(21): 4127-4129.
64. Lu, J. M., D. S. Barrington, et al. (2007). 'Molecular phylogeny of the polystichoid ferns in Asia based on rbcL sequences.' Systematic Botany 32(1): 26-33.
65. Lu, L., H. Wang, et al. (2007). 'Pollen morphology of the tribe Rhinantheae (Orobanchaceae) and its systematic significances.' Plant Systematics and Evolution 268(1-4): 177-198.
66. Ma, C. L., R. K. Moseley, et al. (2007). 'Plant diversity and priority conservation areas of Northwestern Yunnan, China.' Biodiversity and Conservation 16(3): 757-774.
67. Ma, J., P. J. Zhao, et al. (2007). 'New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum .' Archives of Pharmacal Research 30(6): 670-673.
68. Ma, X. X., F. T. Jiang, et al. (2007). 'New pregnane glycosides from the roots of Cynanchum otophyllum .' Steroids 72(11-12): 778-786. 69. Melick, D., Yang, X. F., et al. (2007). 'Seeing the wood for the trees: how conservation policies can place greater pressure on village forests in southwest China.' Biodiversity and Conservation 16(6): 1959-1971. 70. Mu, S. Z., C. S. Li, et al. (2007). 'Daphnipaxianines A-D, alkaloids from Daphniphyllum paxianum .' Journal of Natural Products 70(10): 1628-1631.
71. Mu, S. Z., X. W. Yang, et al. (2007). 'Secophnane-type alkaloids from Daphniphyllum oldhami .' Chemistry & Biodiversity 4(2): 129-138.
72. Nie Z. L., J. Wen, et al. (2007). 'Phylogeny and biogeography of Sassafras (Lauraceae) disjunct between eastern Asian and eastern North America.' Plant Systematics and Evolution 267:191-203.
73. Niu D. L., L. S Wang, et al. (2007). 'A chemotaxonomic study of Lethariella zahlbruckneri and L. smithii (lichenized Ascomycota, Parmeliaceae) from Hengduanshan Mountains.' Lichenologist 39(6): 549-553. 74. Pu, J. X., S. X. Huang, et al. (2007). 'Isolation and structure elucidation of kadlongilactones C-F from Kadsura longipedunculata by NMR spectroscopy and DFT computational methods.' Journal of Natural Products 70(11): 1706-1711.
75. Pu, J. X., W. L. Xiao, et al. (2007). 'Three new compounds from Kadsura longipedunculata. ' Helvetica Chimica Acta 90(4): 723-729.
76. Qiao, Y., X. M. Zhang, et al. (2007). 'Two novel lanostane triterpenoids from Ganoderma sinense .' Molecules 12(8): 2038-2046.
Annual Report 2007 51 77. Gu Q., Y. B. Ma, et al. (2007). 'One new flavanoid and Anti-HIV active constituents from Boussingaultia gracilis Miers var. pseudobaselloides Bailey.' Chemical Journal of Chinese Universities- Chinese 28(8): 1508-1511.
78. Ren, Y. L., Q. R. Tang, et al. (2007). 'Two new tetranortriterpenoids from Cipadessa cinerascens .' Helvetica Chimica Acta 90(4): 764-768.
79. Shao, H. J., C. J. Wang, et al. (2007). 'Pubescenone, a new marasmane sesquiterpenoid from the mushroom Lactarius pubescens.' Heterocycles 71(5): 1135-1139.
80. Shen Y. G., Z. L. Wang, K. Y. Guan.(2007). 'Karyotypes of thirteen species of Iris L. from China' Acta Phytotaxonomica Sinica 45 (5): 601-618.
81. Shui, Y. M. (2007). 'Begonia tetralobata (Begoniaceae), a new species from China.' Annales Botanici Fennici 44(1): 76-79.
82. Song, W. Y., Y. B. Ma, et al. (2007). 'Two new compounds and anti-HIV active constituents from Illicium verum .' Planta Medica 73(4): 372-375.
83. Song, Y. L., Y. H. Wang, et al. (2007). 'Two new triterpenoids from Photinia serrulata .' Molecules 12(12): 2599-2604.
84. Sun, L. R., C. Qing, et al. (2007). 'Cimicifoetisides A and B, two cytotoxic cycloartane triterpenoid glycosides from the rhizomes of Cimicifuga foetida , inhibit proliferation of cancer cells.' Beilstein Journal of Organic Chemistry 3: 6.
85. Sun, L. R., J. Yan, et al. (2007). 'Cimicifine A: A novel triterpene alkaloid from the rhizomes of Cimicifuga foetida .' Helvetica Chimica Acta 90(7): 1313-1318.
86. Sun, W. B., C. Y. Han, et al. (2007). 'Genetic diversity of the rare Asian plant, Trigonobalanus doichangensis (Fagaceae).' Australian Journal of Botany 55(1): 10-17.
87.Sun, W. B., Y. Zhou,et al.(2007).'Chinese Magnolias- it's mostly as bad as we thought'. Oryx 41(4):427-428.
88. Wang, D., M. Xu, et al. (2007). 'Biotransformation of gentiopicroside by asexual mycelia of Cordyceps sinensis .' Bioorganic & Medicinal Chemistry Letters 17(11): 3195-3197.
89. Wang, F., Z. J. Dong, et al. (2007). 'Benzopyran-4-one derivatives from the fungus Ganoderma applanatum .' Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 62(10): 1329- 1332. 90. Wang, H. X., T. Yang, et al. (2007). 'Expression analysis of the gastrodianin gene ga4B in an achlorophyllous plant Gastrodia elata Bl.' Plant Cell Reports 26(3): 253-259.
91. Wang, K. J., C. R. Yang, et al. (2007). 'Phenolic antioxidants from Chinese toon (fresh young leaves and shoots of Toona sinensis ).' Food Chemistry 101(1): 365-371.
52 Annual中国科学院昆明植物研究所年报 Report 2007 2007 92. Wang, L. Q., J. H. Wang, et al. (2007). 'Three new C-21 steroidal glycosides from the roots of Cynanchum inamoenum.' Chinese Chemical Letters 18(10): 1235-1238.
93. Wang, M. Z., X. H. Cai, et al. (2007). 'A novel norditerpene from Eupatorium adenophorum .' Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 62(4): 577-579.
94. Wang, Q., S. D. Luo, et al. (2007). 'Two novel nortriterpenoids from Gomphostemma parviflorum .' Helvetica Chimica Acta 90(7): 1360-1365.
95. Wang, X. H. (2007). 'Type studies of Lactarius species published from China.' Mycologia 99(2): 253-268.
96. Wang Y. F., X. Y. Wang, et al. (2007). 'Three new sesquiterpenoids from the aerial parts of Homalomena occulta .' Chemistry & Biodiversity 4(5):925-931.
97. Wang, Y. H., S. Gao, et al. (2007). 'Structure elucidation and biomimetic synthesis of hostasinine A, a new benzylphenethylamine alkaloid from Hosta plantaginea .' Organic Letters 9(25): 5279- 5281. 98. Wang, Y. H., J. G. Tang, et al. (2007). 'Flazinamide, a novel beta-carboline compound with anti- HIV actions.' Biochemical and Biophysical Research Communications 355(4): 1091-1095.
99. Wang, Y. H., Z. K. Zhang, et al. (2007). 'Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase.' Journal of Natural Products 70(9): 1458-1461.
100. Wang, Y. H., Z. K. Zhang, et al. (2007). 'Stilbene C-glucosides from Cissus repens .' Journal of Asian Natural Products Research 9(7): 631-636.
101. Wei, Z. D., Y. M. Shui, et al. (2007). 'Begonia coelocentroides Y. M. Shui & Z. D. Wei, a new species of Begoniaceae from Yunnan, China.' Acta Phytotaxonomica Sinica 45(1): 86-89.
102. Weng Z. Y., S. X. Huang, et al. (2007). 'Isolation of Two Bioactive ent-Kauranoids from the Leaves of Isodon xerophilus .' Journal of Agriculture and Food Chemistry. 55: 6039-6043.
103. Wu, Y. R., Y. B. Ma, et al. (2007). 'Two new quaternary alkaloids and anti-hepatitis B virus active constituents from Corydalis saxicola .' Planta Medica 73(8): 787-791.
104. Wu, Y. R., Y. X. Zhao, et al. (2007). 'Isoquinoline alkaloids from Corydalis teliensis .' Z. Naturforschung 62b: 1199-1202.
105. Wu, Z. Y., J. X. Wang, et al. (2007). 'Huma should be Linum usitatissimum , not Sesamum indicum - With special reference to the source of confusion of names for traditional Chinese medicine and the written time and author of Shen Nung Pen Ts'ao Ching.' Acta Phytotaxonomica Sinica 45(4): 458-472.
106. Xiao, H. T., X. Y. Hao, et al. (2007). 'Bisabolane-type sesquiterpenoids from the rhizomes of Glochidion coccineum .' Helvetica Chimica Acta 90(1): 164-170.
Annual Report 2007 53 107. Xiao, W. L., S. H. Li, et al. (2007). 'Two new coumarin glucosides from the roots of Angelica apaensis and their anti-platelet aggregation activity.' Archives of Pharmacal Research 30(7): 799- 802.
108. Xiao, W. L., X. L. Li, et al. (2007). 'Triterpenoids from Schisandra rubriflora .' Journal of Natural Products 70(6): 1056-1059.
109. Xiao, W. L., J. X. Pu, et al. (2007). 'Isolation and structure elucidation of nortriterpenoids from Schisandra rubriflora .' Helvetica Chimica Acta 90(8): 1505-1513.
110. Xiao, W. L., L. M. Yang, et al. (2007). 'Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera.' Tetrahedron Letters 48(31): 5543-5546.
111. Xu, F. Q., H. M. Zhong, et al. (2007). 'Steroidal saponins from Lysimachia paridiformis. ' Journal of Asian Natural Products Research 9(6): 493-497.
112. Xu, G., A. J. Hou, et al. (2007). 'Przewalskin B, a novel diterpenoid with an unprecedented skeleton from Salvia przewalskii Maxim.' Organic Letters 9(2): 291-293.
113. Xu, J. C. and D. R. Melick (2007). 'Rethinking the effectiveness of public protected areas in southwestern China.' Conservation Biology 21(2): 318-328.
114. Xu, J. P., H. Guo, et al. (2007). 'Single nucleotide polymorphisms in the ectomycorrhizal mushroom Tricholoma matsutake .' Microbiology-SGM 153: 2002-2012.
115. Xu, M., Z. J. Zha, et al. (2007). 'Phenolic antioxidants from the whole plant of Phyllanthus urinaria .' Chemistry & Biodiversity 4(9): 2246-2252.
116. Xue, C. Y., T. N. Ho, et al. (2007). 'Embryology of Swertia (Gentianaceae) relative to taxonomy.' Botanical Journal of the Linnean Society 155(3): 383-400.
117. Xue, C. Y. and D. Z. Li (2007). 'Molecular identification of the traditional Tibetan medicinal plant Gentianopsis paludosa (Gentianaceae) using diagnostic PCR and PCR-RFLP based on nrDNA ITS regions.' Planta Medica 73(9): 1011-1012.
118. Xue, C. Y., H. Wang, et al. (2007). 'Female gametophyte and seed development in Musella lasiocarpa (Musaceae), a monotypic genus endemic to Southwestern China.' Canadian Journal of Botany-Revue Canadienne De Botanique 85(10): 964-975.
119. Yang, H. Q. and D. Z. Li (2007). 'Two new combinations in Cephalostachyum (Poaceae: Bambusoideae).' Annales Botanici Fennici 44(2): 155-156. 120. Yang, H. Q., S. Peng, et al. (2007). 'Generic delimitations of Schizostachyum and its allies (Gramineae: Bambusoideae) inferred from GBSSI and trnL-F sequence phylogenies.' Taxon 56(1): 45-54. 121. Yang, W. Q., X. D. Qin, et al. (2007). 'New phenyl-ethanediols from the culture broth of Boletus edulis .' Journal of Basic Microbiology 47(2): 191-193.
54 Annual中国科学院昆明植物研究所年报 Report 2007 2007 122. Yang, X., S. G. Lu, et al. (2007). 'First report of chromosome numbers of the Carlemanniaceae (Lamiales).' Journal of Plant Research 120(6): 707-712.
123. Yang, X. L., K. L. Hsieh, et al. (2007). 'Guajadial: An unusual meroterpenoid from guava leaves Psidium guajava .' Organic Letters 9(24): 5135-5138.
124. Yang, X. W., J. S. Wang, et al. (2007). 'Bioactive Phenols from the leaves of Baccaurea ramiflora .' Planta Medica 73(13): 1415-1417.
125. Yang, X. W., J. S. Wang, et al. (2007). 'Tarennane and tarennone, two novel chalcone constituents from Tarenna attenuata.' Planta Medica 73(5): 496-498.
126. Yang, X. W., P. J. Zhao, et al. (2007). 'Mixed lignan-neolignans from Tarenna attenuata .' Journal of Natural Products 70(4): 521-525.
127. Yang, Z. L. (2007). 'Clitopilus amygdoliformis , a new species from tropical China.' Mycotaxon 100: 241-246.
128. Yang, Z. L. (2007). 'Type studies on Chamaeota species described from China.' Mycotaxon 100: 279-287.
129. Yu, F. Q., G. B. Xu, et al. (2007). 'A new and noteworthy species of Hygrophorus from Yunnan, China.' Mycotaxon 100: 169-175.
130. Yu, Y. F., Q. Lu, et al. (2007). 'Myricananone and myricananadiol: Two new cyclic 'Diarylheptanoids' from the roots of Myrica nana.' Helvetica Chimica Acta 90(9): 1691-1696.
131. Zhang, J. L., C. Q. Zhang, et al. (2007). 'Natural hybridization origin of Rhododendron agastum (Ericaceae) in Yunnan, China: inferred from morphological and molecular evidence.' Journal of Plant Research 120(3): 457-463.
132. Zhang, J. W., H. Sun, et al. (2007). 'Karyological studies on the Sino-Himalayan endemic Soroseris and two related genera of tribe Lactuceae (Asteraceae).' Botanical Journal of the Linnean Society 154(1): 79-87. 133. Zhang, M. D., W. H.Chen, et al. (2007). 'Miscellaneous notes on the tribe Gardenieae (Rubiaceae) from China and Vietnam.' Acta Phytotaxonomica Sinica 45(1): 90-93. 134. Zhang, S. B., H. Hu, et al. (2007). 'Flexible and reversible responses to different irradiance levels during photosynthetic acclimation of Cypripedium guttatum .' Journal of Plant Physiology 164(5): 611-620.
135. Zhang, S. B., Z. K. Zhou, et al. (2007). 'Gas exchange and resource utilization in two alpine oaks at different altitudes in the Hengduan Mountains.' Canadian Journal of Forest Research-Revue Canadienne De Recherche Forestiere 37(7): 1184-1193.
136. Zhang, Y., H. Sun., et al. (2007). 'Two new species of Wikstoroemia (Thymelaeaceae) from western Sichuan, China. ' Rhodora 109(940):448-455.
Annual Report 2007 55 137. Zhang, Y., H. P. He, et al. (2007). 'Paxiphyllines a and b, new alkaloids from Daphniphyllum paxianum .' Tetrahedron Letters 48(52): 9104-9107.
138. Zhang Y.H., D.E.Boufford, et al. (2007). 'Taxonomic note on Wikstroemia salicina (Thymelaeaceae).' Acta Phytotaxonomica Sinica 45(3):413-414.
139. Zhang, Y. M., N. H. Tan, et al. (2007). 'Triterpenoid saponins from Metadina trichotoma .' Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 62(5): 745-748.
140. Zhang, Y. M., N. H. Tan, et al. (2007). 'Chamobtusin a, a novel skeleton diterpenoid alkaloid from Chamaecyparis obtusa cv. tetragon .' Organic Letters 9(22): 4579-4581.
141. Zhang, Z., G. M. Liu, et al. (2007). 'A new isoflavonolignan fromPueraria alopecuroides Craib.' Chinese Chemical Letters 18(3): 297-299.
142. Zhang, Z. Q., J. C. Chen, et al. (2007). 'Two new cholestane bisdesmosides from Reineckia carnea .' Helvetica Chimica Acta 90(3): 616-622.
143. Zhao P. J., H. X. Wang, et al. (2007). 'Secondary Metabolites from Endophytic Streptomyces sp. Lz531.' Chemistry and Biodiversity 4: 899-904.
144. Zhao, Q. S., Y. W. Cong (2007). 'Michael reaction acceptor molecules in chemical biology.' Progress in Chemistry 19(12): 1972-1976.
145. Zhao, Y. B., Y. M. Shen, et al. (2007). 'Antifungal agent and other constituents from Cynanchum otophyllum .' Natural Product Research 21(3): 203-210.
146. Zhou, Z. K., Q. S. Yang, et al. (2007). 'Fossils of Quercus sect. Heterobalanus can help explain the uplift of the Himalayas.' Chinese Science Bulletin 52(2): 238-247.
147. Zhu, H. J., J. Ren, et al. (2007). 'Matrix model to predict specific optical rotations of acyclic chiral molecules.' Tetrahedron 63(10): 2292-2314.
148. Zhu, W. M., Q. Zhao, et al. (2007). 'Sesquiterpenoids from Hedychium yunnanense and Porana discifera , and the structural revision of two sesquiterpenoids from Laggera pterodonta .' Journal of Asian Natural Products Research 9(3): 277-283.
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1. Cheng, P., Z. Y. Jiang, et al. (2007). 'Synthesis and biological evaluation of N-acetyl-beta-aryl- 1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro.' Bioorganic & Medicinal Chemistry Letters 17(16): 4476-4480.
2. Dillon, M. O., T. Tu, et al. (2007). 'Phylogeny of Nolana (Nolaneae, Solanoideae, Solanaceae) as inferred from granule-bound starch synthase I (GBSSI) sequences.' Taxon 56(4): 1000-1011.
56 Annual中国科学院昆明植物研究所年报 Report 2007 2007 3. Dong, J. Y., Y. H. Zhu, et al. (2007). 'Nematicidal resorcylides from the aquatic fungus Caryospora callicarpa YMF1.01026.' Journal of Chemical Ecology 33(5): 1115-1126.
4. Jacques, F. M. B. and S. X. Guo (2007). 'Palaeoskapha sichuanensis gen. et sp nov (Menispermaceae) from the Eocene Relu Formation in western Sichuan, West China.' Acta Phytotaxonomica Sinica 45(4): 576-582.
5. Kang, W. Y., B. R. Mang, et al. (2007). 'Isolation and identification of a new triterpene from Neonauclea sessilifolia.' Chemical Journal of Chinese Universities-Chinese 28(11): 2096-2098.
6. Körner, C., M. Donoghue, et al. (2007). 'Creative use of mountain biodiversity databases: The Kazbegi research agenda of GMBA-DIVERSITAS.' Mountain Research and Development 27(3): 276- 281.
7. Kuroda, C., K. Kiuchi, et al. (2007). 'Chemical and genetic diversity of Ligularia latihastata and Ligularia villosa in Yunnan Province of China.' Chemistry & Biodiversity 4(9): 2210-2217.
8. Li, H., T. Tanaka, et al. (2007). 'Rubusuaviins a-f, monomeric and oligomeric ellagitannins from Chinese sweet tea and their alpha-amylase inhibitory activity.' Chemical & Pharmaceutical Bulletin 55(9): 1325-1331.
9. Li, Y. M., Y. T. Jia, et al. (2007). 'Purification and characterization of a new ribosome inactivating protein from cinchonaglycoside C-treated tobacco leaves.' Journal of Integrative Plant Biology 49(9): 1327-1333.
10. Liden, M. and Z. Y. Su (2007). 'New species of Corydalis (Fumariaceae) from China II.' Novon 17(4): 479-496.
11. Liu, H. Y., S. J. Li, et al. (2007). 'Four new podocarpane-type trinorditerpenes from Aleurites moluccana.' Helvetica Chimica Acta 90(10): 2017-2023.
12. Lu, Y. B., N. C. Kong, et al. (2007). 'Paxdaphnine B: a 1,19-bisnor-daphniphyllum alkaloid.' Acta Crystallographica Section E-Structure Reports Online 63: O589-O591.
13. Luo, D. Q., Y. Gao, et al. (2007). 'Highly oxidized humulane Sesquiterpenes from the basidiomycete Lactarius mitissimus.' Journal of Antibiotics 60(2): 162-165.
14. Luo, D. Q., Y. Gao, et al. (2007). 'Two new highly oxidized humulane sesquiterpenes from the basidiomycete Lactarius mitissimus.' Helvetica Chimica Acta 90(6): 1112-1116.
15. Luo, H., Y. J. Liu, et al. (2007). 'Coprinus comatus damages nematode cuticles mechanically with spiny balls and produces potent toxins to immobilize nematodes.' Applied and Environmental Microbiology 73(12): 3916-3923.
16. Matheny, P. B., Z. Wang, et al. (2007). 'Contributions of rpb2 and tef1 to the phylogeny of mushrooms and allies (Basidiomycota, Fungi).' Molecular Phylogenetics and Evolution 43(2): 430- 451.
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18. Möller, M., L. M. Gao, et al. (2007). 'Morphometric analysis of the Taxus wallichiana complex (Taxaceae) based on herbarium material.' Botanical Journal of the Linnean Society 155(3): 307- 335.
19. Nagano, H., Y. Iwazaki, et al. (2007). 'High diversity of Ligularia dictyoneura in chemical composition and DNA sequence.' Chemistry & Biodiversity 4(12): 2874-2888.
20. Nakata, M., K. Y. Guan, et al. (2007). 'Cytotaxonomy of Begonia rubropunctata and B· purpureofolia (Begoniaceae).' Botanical Journal of the Linnean Society 155(4): 513-517.
21. Penman, T. D., R. P. Kavanagh, et al. (2007). 'Patchiness of prescribed bums in dry sclerophyll eucalypt forests in South-eastern Australia.' Forest Ecology and Management 252(1-3): 24-32.
22. Pi, H. F., P. Zhang, et al. (2007). 'A new cycloartane triterpenoid from the leaves and stems of Fritillaria hupehensis.' Chinese Chemical Letters 18(4): 418-420.
23. Qiao, L. R., L. Yuan, et al. (2007). 'Tricycloalternarene derivatives produced by an endophyte Alternaria alternata isolated from Maytenus hookeri.' Journal of Basic Microbiology 47(4): 340-343.
24. Ruan, H. L., X. F. Zhou, et al. (2007). 'Ferulic acid esters from Euphorbia hylonoma.' Fitoterapia 78(1): 72-73.
25. Shi, S. Y., D. Y. Wu, et al. (2007). 'Four new eremophilendiolides from Ligularia atroviolacea.' Chinese Chemical Letters 18(1): 59-61.
26. Shi, S. Y., Q. Zhou, et al. (2007). 'Four new constituents from Taraxacum mongolicum.' Chinese Chemical Letters 18(11): 1367-1370.
27. Taechowisan, T., P. Tuntiwachwuttikul, et al. (2007). 'Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells.' Immunological Investigations 36(2): 203-211.
28. Tan, A. M., H. P. He, et al. (2007). 'Two new sesquiterpenes from Ligularia lankongensis.' Helvetica Chimica Acta 90(1): 101-104.
29. Tori, M., M. Fujiwara, et al. (2007). 'New oplopane-type sesquiterpenoids from Ligularia duciformis.' Natural Product Communications 2(4): 357-360.
30. Torihata, A., R. Hanai, et al. (2007). 'Chemical and genetic differentiation of Ligularia tsangchanensis in Yunnan and Sichuan Provinces of China.' Chemistry & Biodiversity 4(3): 500- 507.
31. Wang, L., W. L. Zhao, et al. (2007). 'Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappa B and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner.' Cell Death and Differentiation 14(2): 306-317.
58 Annual中国科学院昆明植物研究所年报 Report 2007 2007 32. Wang, Y. S., J. H. Yang, et al. (2007). 'New cytotoxic steroid from Stachyurus himalaicus var. himalaicus.' Molecules 12(3): 536-542.
33. Welti, R., J. Shah, et al. (2007). 'Plant lipidomics: Discerning biological function by profiling plant complex lipids using mass spectrometry.' Frontiers in Bioscience 12: 2494-2506.
34. Wen, J., Z. L. Nie, et al. (2007). 'Phylogeny of Vitaceae based on the nuclear GAI1 gene sequences'.' Canadian Journal of Botany-Revue Canadienne De Botanique 85(8): 731-745.
35. Wu, L., Y. Lu, et al. (2007). 'Study on the spatial structure of annomuricatin A, a cyclohexapeptide from the seeds of Annona muricata.' Journal of Molecular Structure 827(1-3): 145-148. 36. Xie, C. Y., H. Zhu, et al. (2007). 'MFTZ-1, an actinomycetes subspecies-derived antitumor macrolide, functions as a novel topoisomerase II poison.' Molecular Cancer Therapeutics 6(11): 3059-3070.
37. Xu, M., D. Wang, et al. (2007). 'Dammarane triterpenoids from the roots of Gentiana rigescens.' Journal of Natural Products 70(5): 880-883.
38. Yan, F. L., L. B. Zhang, et al. (2007). 'Two new diterpenoids from Isodon serra.' Chinese Chemical Letters 18(11): 1383-1385.
39. Yan, F. L., L. B. Zhang, et al. (2007). 'Two new diterpenoids and other constituents from Isodon serra.' Journal of Chemical Research-S(6): 362-364.
40. Yang, S. X., J. M. Gao, et al. (2007). 'Chemical constituents from Craibiodendron yunnanense.' Helvetica Chimica Acta 90(8): 1477-1481.
41. Ye, G., H. Peng, et al. (2007). 'Ellagic acid derivatives from the stem bark of Dipentodon sinicus.' Chemistry of Natural Compounds 43(2): 125-127.
42. Ye, G., H. Peng, et al. (2007). 'A new hopane triterpene from Dipentodon sinicus (Celastraceae).' Biochemical Systematics and Ecology 35(12): 905-908.
43. Ye, M., X. J. Luo, et al. (2007). 'Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway.' Cancer Letters 258(2): 199-207.
44. Yong, M., G. Kun, et al. (2007). 'A new lignan from the seeds of Arctium lappa.' Journal of Asian Natural Products Research 9(6): 541-544.
45. Yu, X. Z., J. D. Gu, et al. (2007). 'Hexavalent chromium induced stress and metabolic responses in hybrid willows.' Ecotoxicology 16(3): 299-309.
46. Yu, Z. Y., Y. G. Liang, et al. (2007). 'Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents.' International Journal of Cancer 121(9): 2084-2094.
Annual Report 2007 59 47. Zeng, Y. B., W. L. Mei, et al. (2007). 'Two new epimeric pairs of iridoid from mangrove plant Scyphiphora hydrophyllacea.' Chinese Chemical Letters 18(12): 1509-1511.
48. Zhang, H. P., F. Chen, et al. (2007). 'Complete assignments of H-1 and C-13 NMR data rings A,B-seco limonoids from the seed of Aphanamixis polystachya.' Magnetic Resonance in Chemistry 45(2): 189-192.
49. Zhang, Y. H., X. L. Yang, et al. (2007). 'A new veratramine alkaloid from the bulbs of Fritillaria hupehensis.' Chinese Chemical Letters 18(2): 175-177.
50. Zhao, Y., X. M. Niu, et al. (2007). 'Synthesis and cytotoxicity of some new eriocalyxin B derivatives.' European Journal of Medicinal Chemistry 42(4): 494-502.
51. Zheng, X., J. Du, et al. (2007). 'A new steroid from Selaginella pulvinata.' Fitoterapia 78(7-8): 598-599.
52. Zhou, C. X., X. Y. Zhang, et al. (2007). 'Three new diarylheptanoids and their antioxidant property.' Chinese Chemical Letters 18(10): 1243-1246.
53. Zhou, L. G., D. Li, et al. (2007). 'Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea.' Natural Product Research 21(4): 303-309.
54. Zhou, X. F., X. Y. Zhao, et al. (2007). 'Three new triterpenoid saponins from the rhizomes of Impatiens pritzellii var. hupehensis.' Journal of Asian Natural Products Research 9(4): 379-385.
List of Monographs
1. Sheng-Ji PEI, Ethnobotany. Shanghai: Shanghai Scientific and Technical Publishers, 2007.
2. Xing-Jiang LI,Da-Cheng ZHANG, Mu ZANG. Moss Flora of China (English Version). Beijing: Science Press, 2007.
3. Hong WANG, Chang-Qin ZHANG, De-Zhu LI. Checklist of Seed Plants of Lijiang Alpine Botanic Garden. Kunming: Yunnan Science & Technology Press, 2007.
4. Kai-Yun GUAN, Zong-Ming SHI. Rich and Varied Plants in Our World. Beijing: China Forestry Publishing House
60 Annual中国科学院昆明植物研究所年报 Report 2007 2007 APPENDIX 3: LIST OF PATENTS APPLIED AND GRANTED
List of Patents Granted 2007
Application Issue Date of Names of Patents Inventors Patent No. Date Patent
Method for Seedling LONG Chun-Lin, CHENG ZL200410040723.0 2004-9-17 2007-12-19 Propagation of Bulbiet Dasheen Zhi-Ying, LUO Ji-Ying
A Pesticide against Powdery HAO Xiao-Jiang, LI Yan- Mildew on Plants and its Mei, ZHANG Zhong-Kai, HE ZL200510010802.1 2005-5-11 2007-10-24 Preparation Methods and Hong-Ping, ZUO Guo-Ying Application XU Min, ZHANG Ying-Jun, A Preparation Method for WANG Dong, ZHANG Xiang- ZL200510010922.1 2005-7-21 2007-10-24 Gentiopicroside Yu, YANG Chong-Ren
Preparation Method for a Anti- LI Rong-Tao, SUN Han- HIV/AIDS Compound and Dong, ZHENG Yong-Tang, ZL200410040750.8 2004-9-24 2007-9-19 Development & Utilization of WANG Rui-Rui, YANG Liu- Drug Combination Using Its Active Components Meng
LI Rong-Ta, XIAO Wei-Lie, Triterpenoid Compounds and SHEN Yun-Ting, PENG Li- ZL200410079516.6 2004-10-22 2007-8-29 Their Utilization Yan, SUN Han-Dong
ZHANG Ying-Jun, XU Min, A Preparation Method for WANG Dong, YANG Chong- ZL200510010880.1 2005-6-23 2007-5-30 Corilagin Ren
A Preparation Method for Anti- QIU Ming-Hua, WANG Jin, tumor Drug Combination and DU Jiang, QIU Sheng-Xiang, ZL200510010837.5 2005-6-3 2007-3-21 Its Application ZHOU Lin
A Preparation Method for Anti-tumor Compound QIU Ming-Hua, SUN Li- and Development of Drug Rong, QING Chen, ZHANG ZL200410040506.1 2004-8-19 2007-2-7 Combination Using and Its Yan-Li, PEI Sheng-Ji Active Components
List of National New Plant Varieties
Names of New Plant Application Issue Date of Breeders No. of Variety Right Varieties Date Variety Right
ZHANG Chang-Qin, HUANG Yuan, Rhododendron ‘Xilinmen’ 20070023 2006-2-17 2007-9-7 ZHANG Jing-Li, TIAN Wei
ZHANG Chang-Qin, HUANG Yuan, Rhododendron ‘Jiaoyan’ 20070028 2006-2-17 2007-9-7 GAO Lian-Ming
ZHANG Chang-Qin, WU Zhi-Kun, Rhododendron ZHANG Jing-Li, SUN Bao-Ling, 20070024 2006-2-17 2007-9-7 ‘Xuemeiren’ TIAN Wei, QIAO Qin
ZHANG Chang-Qin, FENG Bao- Rhododendron ‘Hongyun’ 20070025 2006-2-17 2007-9-7 Jun, GAO Lian-Ming
Rhododendron molle ZHANG Chang-Qin, HUANG Yuan, 20070026 2006-2-17 2007-9-7 ‘Jinzhizhu’ GAO Lian-Ming
ZHANG Chang-Qin, HUANG Yuan, Rhododendron ‘Ziyan’ 20070027 2006-2-17 2007-9-7 GAO Lian-Ming
Annual Report 2007 61 List of Patents Applied 2007
Application Invention Names Applicant (s) Inventors Application No. date
A Preparation Method for LIU Xi-Kui, XIAO Jian-Chun, LV Natural Sweet Compound, KIB 2007.1.26 200710065642.X Iditol Chun-Chao
CHEN Ji-Jun, WU Ying-Rui, ZHAO Anti-Hepatitis B Drug KIB You-Xing, MA Yun-Bao, YAO Shu- 2007.3.13 200710065709.X Ying, ZHOU Jun
QIU Ming-Hua, YAN Jian, QIU You, A Method for Making of KIB YANG Ye-Kun, ZHANG Xiao-Xiao, LI 2007.3.13 200710065710.2 Biodiesel Zhong-Rong KIB, Institute of Preparation Method for Biotechnology HAO Xiao-Jiang, LI Yan-Mei, CHEN Chemical Activator and Its Gang, LUO Xiao-Dong, ZHANG 2007.3.19 200710065721.0 and Germplasm Application Zhong-Kai, HE Hong-Ping Resources, YAAS
Preparation Method for WANG Hao-Xin, ZENG Ying, SHEN KIB 2007.3.19 200710065724.4 Plant Endophyte Yue-Mao
P r e p a r a t i o n M e t h o d QIU Ming-Hua, YAN Jian, YANG Fu-Mei, for Helicide Huperzine KIB 2007.4.20 200710065827.0 A Aldimine and Its YANG Xiao-Sheng, ZHOU Lin, YI Ping Application
Preparation Method for QIU Ming-Hua, YAN Jian, YANG Fu- Derivative of Huperzine A KIB Mei, YI Ping, ZHOU Lin, YANG Xiao- 2007.4.20 200710065824.7 and Its Application Sheng, SUN Qian-Yun
Preparation Method for QIU Ming-Hua, YAN Jian, YANG Fu-Mei, Acetylcholinesterase KIB 2007.5.11 200710065861.8 Inhibitor and Its YI Ping, ZHOU Lin, YANG Xiao-Sheng Application
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Hybrid Variety of D y s o s m a , D y s o s m a × KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065862.2 honghua Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Michelia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065865.6 Michelia × wanchun Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Michelia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065864.1 Michelia × yilan Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Magnolia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065863.7 Magnolia × yujuan Shu
Preparation Method for LIU Ji-Kai, QING Chen, TANG Jian- Flazin Analogues and Its KIB Guo, LI Chun-Lei, DONG Ze-Jun, 2007.4.12 200710065801.8 Application ZHANG Yan-Li
Asepsis Sowing of LONG Chun-Lin, CHENG Zhi-Ying, LUO Cymbidium tortisepalum KIB 2007.6.8 200710065941.3 and Method for Tissue Ji-Feng Culture P r e p a r a t i o n M e t h o d for N-OR Acetanilide- KIB ZHU Hua-Jie, LV Xiao-Jie 2007.6.15 200710065964.4 Group Compound and Its Application
Preparation Method for 6`- ZHAO Ping, ZHANG Ying-Jun, XU KIB 2007.6.14 200710065956.X O-caffeoyl Arbutin Min, YANG Chong-Ren
62 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Application Invention Names Applicant (s) Inventors Application No. Date
Method for Breeding and ZHANG Chang-Qin, WU Zhi-Kun, Propagation of a New KIB Qiao Qin, ZHANG Jing-Li, SUN Bao- 2007.6.27 200710066000.1 Variety of Rhododendron, Ling, TIAN Wei Rhododendron 'Xuemeiren'
Method for Breeding and ZHANG Chang-Qin, ZHANG Jing-Li, Propagation of a New KIB TIAN Wei, MA Yong-Peng, HUANG 2007.6.27 200710066001.6 Variety of Rhododendron, Yuan, GAO Lian-Ming Rhododendron ‘Jiaoyan’
Method for Breeding and ZHANG Chang-Qin, ZHANG Jing-Li, Propagation of a New KIB 2007.6.27 200710065999.8 Variety of Rhododendron, TIAN Wei, MA Yong-Peng Rhododendron ‘Xilinmen’
Method for Breeding and Propagation of a ZHANG Chang-Qin, Wu Zhi-Kun, New Variety of Ardisia KIB SUN Bao-Ling, GAO Ze-Rui, HUANG 2007.6.27 200710066002.0 japonica, Ardisia mamillata Yuan, LONG Qing-Lin ‘Baimaozhan’
Preparation Method for Cyclopeptide and Its KIB CHENG Yong-Xian, LV Qing 2007.7.13 200710066034.0 Application
CHEN Ke-Ke, ZHU Hong-Taom Production Method for WANG Dong, YANG Chong-Ren, Pile-Fermentation of a Pu- KIB 2007.8.30 200710066150.2 ZHANG Ying-Jun, ZHANG Xiang- Er Ripe Tea Lan
Preparation Method for ZHANG Ying-Jun, XU Min, CHEN Prepared Chinese Angelica KIB Jiang-Tao, WANG Dong, YANG 2007.8.30 200710066149.X and Its Application Chong-Ren
KIB, Kunming An Anti-Depression Drug Institute of Zoology, CHEN Ji-Jun, XU Lin, ZHOU Jun, LV Jun, MAO Rong-Rong, TIAN Meng, 2007.8.3 200710066088.7 and Its Application Kunming Jingbiao SHEN Yong, JIANG Zhi-Yong Biotech Co., Ltd. KIB, Kunming CHEN Ji-Jun, XU Lin, ZHOU Jun, LV Anti-Depression Drugs and Institute of Zoology, Jun, MAO Rong-Rong, TIAN Meng, 2007.8.3 200710066089.1 Kunming Jingbiao Application ZHANG Xue-Mei, SHEN Yong Biotech Co., Ltd.
Preparation Method PU Jian-Xin, SUN Han-Dong, XIAO for Anti-Tumor Activity Compound and Its KIB Wei-Lie, LI Rong-Tao, HUANG 2007.8.1 200710138589.1 Application Sheng-Xiong
Notoginseng and Standard Extract of Notoginseng, WANG Dong, LIAO Peng-Ying, KIB 2007.9.14 200710066195.X PN450 and Their ZHANG Ying-Jun, YANG Chong-Ren Application
Preparation Method for ZHU Hua-Jie, JIANG Ju-Xing, REN Carboline Compound and KIB 2007.11.9 200710066368.8 Jie Its Application
Annual Report 2007 63 List of Patents Applied and Granted 2007
Application Invention Names Applicant (s) Inventors Application No. date
A Preparation Method LIU Xi-Kui, XIAO Jian-Chun, LV for Natural Sweet KIB 2007.1.26 200710065642.X Compound, Iditol Chun-Chao
CHEN Ji-Jun, WU Ying-Rui, ZHAO Anti-Hepatitis B Drug KIB You-Xing, MA Yun-Bao, YAO Shu- 2007.3.13 200710065709.X Ying, ZHOU Jun
QIU Ming-Hua, YAN Jian, QIU You, A Method for Making of KIB YANG Ye-Kun, ZHANG Xiao-Xiao, LI 2007.3.13 200710065710.2 Biodiesel Zhong-Rong KIB, Institute of Preparation Method for Biotechnology and HAO Xiao-Jiang, LI Yan-Mei, CHEN Chemical Activator and Gang, LUO Xiao-Dong, ZHANG 2007.3.19 200710065721.0 Germplasm Resources, Its Application Zhong-Kai, HE Hong-Ping YAAS
Preparation Method for WANG Hao-Xin, ZENG Ying, SHEN KIB 2007.3.19 200710065724.4 Plant Endophyte Yue-Mao
Preparation Method QIU Ming-Hua, YAN Jian, YANG Fu-Mei, for Helicide Huperzine KIB 2007.4.20 200710065827.0 A Aldimine and Its YANG Xiao-Sheng, ZHOU Lin, YI Ping Application
Preparation Method for QIU Ming-Hua, YAN Jian, YANG Fu- Derivative of Huperzine A KIB Mei, YI Ping, ZHOU Lin, YANG Xiao- 2007.4.20 200710065824.7 and Its Application Sheng, SUN Qian-Yun
Preparation Method for QIU Ming-Hua, YAN Jian, YANG Fu-Mei, Acetylcholinesterase KIB 2007.5.11 200710065861.8 Inhibitor and Its YI Ping, ZHOU Lin, YANG Xiao-Sheng Application
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Hybrid Variety of Dysosma, Dysosma × KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065862.2 honghua Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Michelia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065865.6 Michelia × wanchun Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Michelia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065864.1 Michelia × yilan Shu
Breeding Method for a GONG Xun, PAN Yue-Zhi, YANG New Variety of Magnolia, KIB Zhi-Yun, ZHANG Qi-Tai, YUE Zhong- 2007.5.11 200710065863.7 Magnolia × yujuan Shu
Preparation Method for LIU Ji-Kai, QING Chen, TANG Jian- Flazin Analogues and Its KIB Guo, LI Chun-Lei, DONG Ze-Jun, 2007.4.12 200710065801.8 Application ZHANG Yan-Li
Asepsis Sowing of LONG Chun-Lin, CHENG Zhi-Ying, LUO Cymbidium tortisepalum KIB 2007.6.8 200710065941.3 and Method for Tissue Ji-Feng Culture
64 Annual中国科学院昆明植物研究所年报 Report 2007 2007 Application Invention Names Applicant (s) Inventors Application No. Date
Preparation Method for N-OR Acetanilide-Group Compound KIB ZHU Hua-Jie, LV Xiao-Jie 2007.6.15 200710065964.4 and Its Application
Preparation Method for 6`-O- ZHAO Ping, ZHANG Ying-Jun, KIB 2007.6.14 200710065956.X caffeoyl Arbutin XU Min, YANG Chong-Ren
Method for Breeding and ZHANG Chang-Qin, ZHANG Propagation of a New Jing-Li, TIAN Wei, MA Yong- KIB 2007.6.27 200710066001.6 Variety of Rhododendron, Peng, HUANG Yuan, GAO Lian- Rhododendron ‘Jiaoyan’ Ming
Method for Breeding and ZHANG Chang-Qin, Wu Zhi- Propagation of a New Variety Kun, SUN Bao-Ling, GAO Ze- KIB 2007.6.27 200710066002.0 of Ardisia japonica, Ardisia Rui, HUANG Yuan, LONG Qing- mamillata ‘Baimaozhan’ Lin
KIB, Kunming CHEN Ji-Jun, XU Lin, ZHOU Jun, An Anti-Depression Drug and Institute of Zoology , LV Jun, MAO Rong-Rong, TIAN 2007.8.3 200710066088.7 Its Application Kunming Jingbiao Meng, SHEN Yong, JIANG Zhi- Biotech Co., Ltd. Yong
Annual Report 2007 65 Editor-in-chief: LI De-Zhu Associate Editors-in-chief: SUN Hang, YANG Yong-Ping, LIU Ji-Kai & GAN Fan-Yuan Editorial Committee: WANG Yu-Hua, WU Shu-Guang, QIAN Jie, ZHOU Zhe-Kun, PENG Hua, TAN Ning-Hua, ZHAO Qin-Shi, SUN Wei-Bang, LI Wei-Qi, YANG Xiang-Yun & ZHOU Bing Executive Editors: QIAN Jie & WANG Yu-Hua Proofreading: HUANG Lu-Lu & ZHANG Jian-Wen Designer: WU Yan
66 Annual中国科学院昆明植物研究所年报 Report 2007 2007