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GSTM2 Monoclonal Antibody (M03), Clone 1E10

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GSTM2 Monoclonal Antibody (M03), Clone 1E10 GSTM2 monoclonal antibody (M03), clone 1E10 Catalog # : H00002946-M03 規格 : [ 100 ug ] List All Specification Application Image Product Mouse monoclonal antibody raised against a partial recombinant Western Blot (Cell lysate) Description: GSTM2. Immunogen: GSTM2 (NP_000839, 90 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: SEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYS QFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFE enlarge Western Blot (Recombinant Host: Mouse protein) Reactivity: Human, Mouse Immunohistochemistry (Formalin/PFA-fixed paraffin- Isotype: IgG1 Kappa embedded sections) Quality Control Antibody Reactive Against Recombinant Protein. Testing: enlarge Immunofluorescence enlarge Western Blot detection against Immunogen (36.74 KDa) . Sandwich ELISA (Recombinant Storage Buffer: In 1x PBS, pH 7.4 protein) Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Instruction: MSDS: Download enlarge Datasheet: Download ELISA Publication Reference 1. A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosis. Ashour N, Angulo JC, Andres G, Alelu R, Gonzalez-Corpas A, Toledo MV, Rodriguez- Barbero JM, Lopez JI, Sanchez-Chapado M, Ropero SProstate. 2014 Sep;74(12):1171- 82. doi: 10.1002/pros.22833. Epub 2014 Jun 24. Applications Western Blot (Cell lysate) Page 1 of 3 2016/5/21 GSTM2 monoclonal antibody (M03), clone 1E10. Western Blot analysis of GSTM2 expression in NIH/3T3 ( Cat # L018V1 ). Protocol Download Western Blot (Recombinant protein) Protocol Download Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlarge this image Immunoperoxidase of monoclonal antibody to GSTM2 on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml] Protocol Download Immunofluorescence enlarge this image Immunofluorescence of monoclonal antibody to GSTM2 on HeLa cell . [antibody concentration 10 ug/ml] Protocol Download Sandwich ELISA (Recombinant protein) Detection limit for recombinant GST tagged GSTM2 is 0.03 ng/ml as a capture antibody. Protocol Download Page 2 of 3 2016/5/21 ELISA Gene Information Entrez GeneID: 2946 GeneBank NM_000848 Accession#: Protein NP_000839 Accession#: Gene Name: GSTM2 Gene Alias: GST4,GSTM,GSTM2-2,GTHMUS,MGC117303 Gene glutathione S-transferase mu 2 (muscle) Description: Omim ID: 138380 Gene Ontology: Hyperlink Gene Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S- transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq Other GST class-mu 2,GST, muscle,OTTHUMP00000013351,S- Designations: (hydroxyalkyl)glutathione lyase M2,glutathione S-alkyltransferase M2,glutathione S-aralkyltransferase M2,glutathione S-aryltransferase M2,glutathione S-transferase 4,glutathione S-transferase M1,glutathione Gene Pathway Drug metabolism - cytochrome P450 Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Related Disease Breast Neoplasms Cardiovascular Diseases Colorectal Neoplasms Coronary Artery Disease Diabetes Mellitus, Type 2 Edema Genetic Predisposition to Disease Helicobacter Infections Hypertension Kidney Failure, Chronic Lung Neoplasms Neoplasms Prenatal Exposure Delayed Effects Stomach Neoplasms 服務條款 | 隱私權政策 | 著作及商標 | 網站地圖 ©2016 亞諾法生技股份有限公司 Abnova Corporation. 版權所有. Page 3 of 3 2016/5/21.
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