2014 1. Abu Shehab, Majida, Ian Damerill, Tong Shen
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Publications for Biochemistry Faculty at Western University (2014-20) 2014 1. Abu Shehab, Majida, Ian Damerill, Tong Shen, Fredrick J. Rosario, Mark Nijland, Peter W. Nathanielsz, Amrita Kamat, Thomas Jansson, and Madhulika B. Gupta. 2014. "Liver mTOR Controls IGF-I Bioavailability by Regulation of Protein Kinase CK2 and IGFBP-1 Phosphorylation in Fetal Growth Restriction." Endocrinology 155 (4):1327-1339. doi: 10.1210/en.2013-1759. 2. Allison, Sarah E., Brian R. Tuinema, Ellen S. Everson, Seiji Sugiman-Marangos, Kun Zhang, Murray S. Junop, and Brian K. Coombes. 2014. "Identification of the Docking Site between a Type III Secretion System ATPase and a Chaperone for Effector Cargo." Journal of Biological Chemistry 289 (34):23734- 23744. doi: 10.1074/jbc.M114.578476. 3. Anderson, Todd J., Jean Gregoire, Robert A. Hegele, Patrick Couture, G. B. John Mancini, Ruth McPherson, Gordon A. Francis, Paul Poirier, David C. Lau, Steven Grover, Jacques Genest, Jr., Andre C. Carpentier, Robert Dufour, Milan Gupta, Richard Ward, Lawrence A. Leiter, Eva Lonn, Dominic S. Ng, Glen J. Pearson, Gillian M. Yates, James A. Stone, and Ehud Ur. 2014. "Are the ACC/AHA Guidelines on the Treatment of Blood Cholesterol a Game Changer? A Perspective From the Canadian Cardiovascular Society Dyslipidemia Panel." Canadian Journal of Cardiology 30 (4):377-380. doi: 10.1016/j.cjca.2014.01.009. 4. Bisanz, J. E., M. K. Enos, J. R. Mwanga, J. Changalucha, J. P. Burton, G. B. Gloor, and G. Reid. 2014. "Randomized open-label pilot study of the influence of probiotics and the gut microbiome on toxic metal levels in Tanzanian pregnant women and school children." mBio 5 (5):e01580-14. doi: 10.1128/mBio.01580-14; 10.1128/mBio.01580-14. 5. Bisanz, J. E., S. Seney, A. McMillan, R. Vongsa, D. Koenig, L. Wong, B. Dvoracek, G. B. Gloor, M. Sumarah, B. Ford, D. Herman, J. P. Burton, and G. Reid. 2014. "A systems biology approach investigating the effect of probiotics on the vaginal microbiome and host responses in a double blind, placebo-controlled clinical trial of post-menopausal women." PloS one 9 (8):e104511. doi: 10.1371/journal.pone.0104511; 10.1371/journal.pone.0104511. 6. Bisanz, Jordan E., Jean M. Macklaim, Gregory B. Gloor, and Gregor Reid. 2014. "Bacterial metatranscriptome analysis of a probiotic yogurt using an RNA-Seq approach." International Dairy Journal 39 (2):284-292. doi: 10.1016/j.idairyj.2014.07.010. 7. Bojic, Lazar A., Amy C. Burke, Sanjiv S. Chhoker, Dawn E. Telford, Brian G. Sutherland, Jane Y. Edwards, Cynthia G. Sawyez, Rommel G. Tirona, Hao Yin, J. Geoffrey Pickering, and Murray W. Huff. 2014. "Peroxisome Proliferator-Activated Receptor delta Agonist GW1516 Attenuates Diet-Induced Aortic Inflammation, Insulin Resistance, and Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice." Arteriosclerosis Thrombosis and Vascular Biology 34 (1):52-60. doi: 10.1161/ATVBAHA.113.301830. 8. Bojic, Lazar A., Dawn E. Telford, Morgan D. Fullerton, Rebecca J. Ford, Brian G. Sutherland, Jane Y. Edwards, Cynthia G. Sawyez, Robert Gros, Bruce E. Kemp, Gregory R. Steinberg, and Murray W. Huff. 2014. "PPAR delta activation attenuates hepatic steatosis in Ldlr(-/-) mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity." Journal of lipid research 55 (7):1254-1266. doi: 10.1194/jlr.M046037. 9. Brace, C., G. B. Gloor, M. Ropeleski, E. Allen-Vercoe, and E. O. Petrof. 2014. "Microbial composition analysis of Clostridium difficile infections in an ulcerative colitis patient treated with multiple fecal microbiota transplantations." Journal of Crohn's & colitis 8 (9):1133-1137. doi: 10.1016/j.crohns.2014.01.020; 10.1016/j.crohns.2014.01.020. 10. Brahm, Amanda, and Robert A. Hegele. 2014. "Is Plant-Based Cardioprotection Evidence-Based?" Canadian Journal of Cardiology 30 (10):1142-1144. doi: 10.1016/j.cjca.2014.04.030. 11. Broecker, Markus J., Joanne M. L. Ho, George M. Church, Dieter Soell, and Patrick O'Donoghue. 2014. "Recoding the Genetic Code with Selenocysteine." Angewandte Chemie-International Edition 53 (1):319- 323. doi: 10.1002/anie.201308584. 1 12. Calder, Michele, Yee-Ming Chan, Renju Raj, Macarena Pampillo, Adrienne Elbert, Michelle Noonan, Carolina Gillio-Meina, Claudia Caligioni, Nathalie G. Berube, Moshmi Bhattacharya, Andrew J. Watson, Stephanie B. Seminara, and Andy V. Babwah. 2014. "Implantation Failure in Female Kiss1(-/-) Mice Is Independent of Their Hypogonadic State and Can Be Partially Rescued by Leukemia Inhibitory Factor." Endocrinology 155 (8):3065-3078. doi: 10.1210/en.2013-1916. 13. Caminsky, N., E. J. Mucaki, and P. K. Rogan. 2014. "Interpretation of mRNA splicing mutations in genetic disease: review of the literature and guidelines for information-theoretical analysis." F1000Research 3:282. doi: 10.12688/f1000research.5654.1; 10.12688/f1000research.5654.1. 14. Carboni, Nicola, Francesco Brancati, Eleonora Cocco, Elisabetta Solla, Maria R. D'Apice, Anna Mateddu, Adam McIntyre, Elisabetta Fadda, Marco Mura, Giovanna Lattanzi, Rachele Piras, Maria A. Maioli, Giovanni Marrosu, Giuseppe Novelli, Maria G. Marrosu, and Robert A. Hegele. 2014. "Partial Lipodystrophy Associated with Muscular Dystrophy of Unknown Genetic Origin." Muscle & nerve 49 (6):928-930. doi: 10.1002/mus.24157. 15. Cecchini, M. J., M. J. Thwaites, S. Talluri, J. I. MacDonald, D. T. Passos, J. L. Chong, P. Cantalupo, P. M. Stafford, M. T. Saenz-Robles, S. M. Francis, J. M. Pipas, G. Leone, I. Welch, and F. A. Dick. 2014. "A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene- targeted mice." Molecular and cellular biology 34 (11):2029-2045. doi: 10.1128/MCB.01589-13; 10.1128/MCB.01589-13. 16. Chapman, M. John, Henry N. Ginsberg, and Robert A. Hegele. 2014. "Treatment of severe hypertriglyceridaemia reply." Lancet Diabetes & Endocrinology 2 (11):860-861. doi: 10.1016/S2213- 8587(14)70054-3. 17. Chitilian, J. M., G. Thillainadesan, J. L. Manias, W. Y. Chang, E. Walker, M. Isovic, W. L. Stanford, and J. Torchia. 2014. "Critical Components of the Pluripotency Network Are Targets for the p300/CBP Interacting Protein ( p/CIP) in Embryonic Stem Cells c." Stem cells 32 (1):204-215. doi: 10.1002/stem.1564. 18. Chong, Robert A., Kenneth Wu, Donald E. Spratt, Yingying Yang, Chan Lee, Jaladhi Nayak, Ming Xu, Rana Elkholi, Inger Tappin, Jessica Li, Jerard Hurwitz, Brian D. Brown, Jerry Edward Chipuk, Zhijian J. Chen, Roberto Sanchez, Gary S. Shaw, Lan Huang, and Zhen-Qiang Pan. 2014. "Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination." Proceedings of the National Academy of Sciences of the United States of America 111 (23):8434-8439. doi: 10.1073/pnas.1407849111. 19. Correa, Rohann J. M., Yudith Ramos Valdes, Teresa M. Peart, Elena N. Fazio, Monique Bertrand, Jacob McGee, Michel Prefontaine, Akira Sugimoto, Gabriel E. DiMattia, and Trevor G. Shepherd. 2014. "Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability." Carcinogenesis 35 (9):1951-1961. doi: 10.1093/carcin/bgu049. 20. Coschi, C. H., C. A. Ishak, D. Gallo, A. Marshall, S. Talluri, J. Wang, M. J. Cecchini, A. L. Martens, V. Percy, I. Welch, P. C. Boutros, G. W. Brown, and F. A. Dick. 2014. "Haploinsufficiency of an RB-E2F1- Condensin II complex leads to aberrant replication and aneuploidy." Cancer discovery 4 (7):840-853. doi: 10.1158/2159-8290.CD-14-0215; 10.1158/2159-8290.CD-14-0215. 21. Cuchel, Marina, Eric Bruckert, Henry N. Ginsberg, Frederick J. Raal, Raul D. Santos, Robert A. Hegele, Jan Albert Kuivenhoven, Borge G. Nordestgaard, Olivier S. Descamps, Elisabeth Steinhagen-Thiessen, Anne Tybjrg-Hansen, Gerald F. Watts, Maurizio Averna, Catherine Boileau, Jan Boren, Alberico L. Catapano, Joep C. Defesche, G. Kees Hovingh, Steve E. Humphries, Petri T. Kovanen, Luis Masana, Paivi Pajukanta, Klaus G. Parhofer, Kausik K. Ray, Anton F. H. Stalenhoef, Erik Stroes, Marja-Riitta Taskinen, Albert Wiegman, Olov Wiklund, M. John Chapman, and Conse European Atherosclerosis Soc. 2014. "Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society." European heart journal 35 (32):2146- U100. doi: 10.1093/eurheartj/ehu274. 22. Dasgupta, Kaberi, Robert R. Quinn, Kelly B. Zarnke, Doreen M. Rabi, Pietro Ravani, Stella S. Daskalopoulou, Simon W. Rabkin, Luc Trudeau, Ross D. Feldman, Lyne Cloutier, Ally Prebtani, Robert J. Herman, Simon L. Bacon, Richard E. Gilbert, Marcel Ruzicka, Donald W. McKay, Tavis S. Campbell, Steven Grover, George Honos, Ernesto L. Schiffrin, Peter Bolli, Thomas W. Wilson, Patrice Lindsay, 2 Michael D. Hill, Shelagh B. Coutts, Gord Gubitz, Mark Gelfer, Michel Vallee, G. V. Ramesh Prasad, Marcel Lebel, Donna McLean, J. Malcolm O. Arnold, Gordon W. Moe, Jonathan G. Howlett, Jean-Martin Boulanger, Pierre Larochelle, Lawrence A. Leiter, Charlotte Jones, Richard I. Ogilvie, Vincent Woo, Janusz Kaczorowski, Kevin D. Burns, Robert J. Petrella, Swapnil Hiremath, Alain Milot, James A. Stone, Denis Drouin, Kim L. Lavoie, Maxime Lamarre-Cliche, Guy Tremblay, Pavel Hamet, George Fodor, S. George Carruthers, George B. Pylypchuk, Ellen Burgess, Richard Lewanczuk, George K. Dresser, S. Brian Penner, Robert A. Hegele, Philip A. McFarlane, Milan Khara, Andrew Pipe, Paul Oh, Peter Selby, Mukul Sharma, and Debra J. Reid. 2014. "The 2014 Canadian Hypertension Education Program Recommendations for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension." Canadian Journal of Cardiology 30 (5):485-501. doi: 10.1016/j.cjca.2014.02.002. 23. Deplus, R., L. Blanchon, A. Rajavelu, A. Boukaba, M. Defrance, J. Luciani, F. Rothe, S. Dedeurwaerder, H. Denis, A. B. Brinkman, F. Simmer, F. Muller, B. Bertin, M. Berdasco, P. Putmans, E. Calonne, D. W. Litchfield, Y. de Launoit, T. P. Jurkowski, H. G. Stunnenberg, C. Bock, C. Sotiriou, M. F.