GENETIC PRIVACY AFTER CARPENTER Natalie Ram*
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An Alternate Universe Lacking the Existence of Genetic Genealogy
Chapter 6 Life Bar ‘The Golden Standard’ – An Alternate Universe Lacking the Existence of Genetic Genealogy Georgina Tomas Genes are like a story, and DNA is the language that story is written in. (Sam Kean, American Author) With forensic DNA analysis widely regarded as the ‘golden standard’ of forensic evidence, case investigations and criminal cases have shown that genetic genealogy is pivotal in discovering who the perpetrator is. Through the interpretation of DNA testing and its new adaptation of credibility towards case investigations, it will lead to the establishment of what genetic genealogy is and how it has made an impact in the progressions of forensic evidence. To propose a hypothetical situation where genetic genealogy does not exist, one can examine the impacts on individuals in society and in investigation. Understanding genetic genealogy is key in ensuring that further advancements take place in the novel field of forensic science, as it concerns the nature of DNA analysis, from the many fallibilities of processing to the standardization practices across all laboratories. The importance of forensic genetics will be distinguished through a hypothetical universe inexistent of genetic genealogy prior to the Golden State Killer (GSK) case. The absence of genetic genealogy will be used to highlight the divergence in an alternate timeline to then unravel the major impacts it would further have on the GSK case. The external consequences that would be involved in the justice system regarding social and privacy-related issues will also be examined. 59 The Forensic Science Alternate Universe Golden State Killer Case Between 1974 and 1986, the name ‘Golden State Killer’ was the moniker for a man by the name of Joseph James DeAngelo. -
Ethical and Legal Issues in Whole Genome Sequencing of Individuals
InFocus Robertson, J. A. 2003. The $1000 Genome: Ethical and Legal Issues in Whole Genome Sequencing of Individuals. The American Journal of Bioethics 3(3):InFocus. The $1000 Genome: Ethical and Legal Issues in Whole Genome Sequencing of Individuals John A. Robertson The University of Texas School of Law Abstract understanding the pathogenesis of disease and to drug Progress in gene sequencing could make rapid whole design will be enormous. The ability to predict genome sequencing of individuals affordable to disease and take preventive action will grow millions of persons and useful for many purposes in a significantly. Molecular staging is becoming an future era of genomic medicine. Using the idea of indispensable tool in oncology, and the need for $1000 genome as a focus, this article reviews the pharmacogenetic assessments before prescribing main technical, ethical, and legal issues that must be drugs is likely to become routine. Within ten years resolved to make mass genotyping of individuals there may also be more effective gene therapies that cost-effective and ethically acceptable. It presents correct the genomic or molecular basis of existing the case for individual ownership of a person’s disease (Guttmacher and Collins 2002). genome and its information, and shows the Many clinical applications of genomics will implications of that position for rights to informed require that an individual’s genome or sections of it consent and privacy over sequencing, testing, and be sequenced, so that the presence or absence of disclosing genomic information about identifiable disease mutations or other relevant information can individuals. Legal recognition of a person’s right to be ascertained. -
Genetic Data Aren't So Special: Causes and Implications of Re
Genetic Data Aren’t So Special: Causes and Implications of Re-identification T.J. Kasperbauer & Peter H. Schwartz Indiana University Center for Bioethics Indiana University School of Medicine This is the pre-peer-reviewed version of the article published here: https://doi.org/10.1002/hast.1183 Full citation: Kasperbauer, T.J. & Schwartz, P.H. (2020). Genetic data aren’t so special: Causes and implications of re-identification. Hastings Center Report, 50, 30-39. Abstract: Genetic information is widely thought to pose unique risks of re-identifying individuals. Genetic data reveals a great deal about who we are, and, the standard view holds, should consequently be treated differently from other types of data. Contrary to this view, we argue that the dangers of re-identification for genetic and non-genetic data—including health, financial, and consumer information—are more similar than has been recognized. Before we impose different requirements on sharing genetic information, proponents of the standard view must show that they are in fact necessary. We further argue that the similarities between genetic and non-genetic information have important implications for communicating risks during consent for healthcare and research. While patients and research participants need to be more aware of pervasive data sharing practices, consent forms are the wrong place to provide this education. Instead, health systems should engage with patients throughout patient care to educate about data sharing practices. Introduction Genetic data and biological samples containing genetic material are widely thought to differ from other sorts of health data due to the impossibility of truly “de-identifying” genetic information. -
Consumer Genetic Testing: a Case Study of 23Andme and Ancestry
THE PRIVACY RISKS OF DIRECT-TO- CONSUMER GENETIC TESTING: A CASE STUDY OF 23ANDME AND ANCESTRY SAMUAL A. GARNER AND JIYEON KIM* ABSTRACT Direct-to-consumer genetic testing (DTC-GT) companies have proliferated and expanded in recent years. Using biospecimens directly submitted by consumers, these companies sequence and analyze the individual’s genetic information to provide a wide range of services including information on health and ancestry without the guidance of a healthcare provider. Given the sensitive nature of genetic information, however, there are growing privacy concerns regarding DTC-GT company data practices. We conduct a rigorous analysis, both descriptive and normative, of the privacy policies and associated privacy risks and harms of the DTC-GT services of two major companies, 23andMe and Ancestry, and evaluate to what extent consumers’ genetic privacy is protected by the policies and practices of these two companies. Despite the exceptional nature of genetic information, the laws and agency regulation surrounding genetic privacy and DTC-GT services are fragmented and insufficient. In this analysis, we propose three categories of privacy harms specific to DTC- GT—knowledge harms, autonomy and trust-based harms, and data misuse harms. Then, through the normative lens of exploitation, we argue that 23andMe and Ancestry’s data practices and privacy policies provide consumers with insufficient protection against these harms. Greater efforts from both the industry and legal system are necessary to protect DTC-GT consumers’ genetic privacy as we advance through the era of genomics and precision medicine. * Samual A. Garner, M. Bioethics, J.D.; Jiyeon Kim, M.S., M.A. -
Ethical Implications of Forensic Genealogy in Criminal Cases
The Journal of Business, Entrepreneurship & the Law Volume 13 Issue 2 Article 6 5-15-2020 Ethical Implications of Forensic Genealogy in Criminal Cases Solana Lund Follow this and additional works at: https://digitalcommons.pepperdine.edu/jbel Part of the Criminal Law Commons, Legal Ethics and Professional Responsibility Commons, Privacy Law Commons, and the Science and Technology Law Commons Recommended Citation Solana Lund, Ethical Implications of Forensic Genealogy in Criminal Cases, 13 J. Bus. Entrepreneurship & L. 185 (2020) Available at: https://digitalcommons.pepperdine.edu/jbel/vol13/iss2/6 This Comment is brought to you for free and open access by the Caruso School of Law at Pepperdine Digital Commons. It has been accepted for inclusion in The Journal of Business, Entrepreneurship & the Law by an authorized editor of Pepperdine Digital Commons. For more information, please contact [email protected], [email protected], [email protected]. ETHICAL IMPLICATIONS OF FORENSIC GENEALOGY IN CRIMINAL CASES Solana Lund* I. FORENSIC GENEALOGY .................................................186 II. DIRECT TO CONSUMER DATABASES ..........................189 A. Terms and Conditions ......................................... 189 B. Regulations ......................................................... 192 C. GEDmatch........................................................... 193 III. A SUMMARY OF CRIMINAL CASES THAT HAVE USED DTC AND FORENSIC GENEALOGY ...............................195 IV. ETHICAL IMPLICATIONS -
Advanced Statistical Population Genetics Methods for Forensic DNA Identification Author(S): Noah A
The author(s) shown below used Federal funding provided by the U.S. Department of Justice to prepare the following resource: Document Title: Advanced Statistical Population Genetics Methods for Forensic DNA Identification Author(s): Noah A. Rosenberg, Ph.D. Document Number: 253932 Date Received: October 2019 Award Number: 2014-DN-BX-K015 This resource has not been published by the U.S. Department of Justice. This resource is being made publically available through the Office of Justice Programs’ National Criminal Justice Reference Service. Opinions or points of view expressed are those of the author(s) and do not necessarily reflect the official position or policies of the U.S. Department of Justice. Basic Research and Development in Forensic Science for Criminal Justice Purposes Department of Justice, Office of Justice Programs National Institute of Justice NIJ SL # SL001082 NIJ‐2014‐3744 Award # 2014‐DN‐BX‐K015 ADVANCED STATISTICAL POPULATION GENETICS METHODS FOR FORENSIC DNA IDENTIFICATION Prepared by: Noah A. Rosenberg, PhD Principal Investigator Department of Biology Stanford University 371 Gilbert Building, Room 109 Stanford, CA 94305‐5020 Tel: 650 721 2599 Email: [email protected] Prepared on: January 10, 2019 Recipient Organization: Board of Trustees of the Leland Stanford Junior University Stanford University 3160 Porter Drive, Suite 100 Palo Alto, CA 94304‐8445 Final Progress Report Project Period: 01/01/2015 – 12/31/2018 Signature of Submitting Official: Robert Loredo, Contract and Grant Officer 01/24/2019 This resource was prepared by the author(s) using Federal funds provided by the U.S. Department of Justice. Opinions or points of view expressed are those of the author(s) and do not necessarily reflect the official position or policies of the U.S. -
DNA DOE Project Our First Two Years of Success
DNA DOE Project Our First Two Years of Success ISHI 30 24 Sep 2019 Colleen Fitzpatrick, PhD Margaret Press, PhD Co-Founders DNA Doe Project DNA DOE Project Chronology • Feb 2017 First discussions • Jul 10, 2017 First sample sent to lab for sequencing • Sep 27, 2017 Joseph Chandler case uploaded to GEDmatch • Oct 2017 Incorporated as 501(c)3 • Mar 6, 2017 Joseph Newton Chandler identified • Mar 29, 2017 Buckskin Girl Identified DNA Doe Project Stats Sept 2019 Volunteers ~ 70 Shortest Solve Time 4 hrs Longest Solve Time 19 ½ mos Avg Solve Time 60 days (no outliers) More DNA Doe Project Stats Sep 2019 Waiting shipment to lab 3 Bone extraction stage 6 DNA Processing 19 Bioinformatics 7 Genealogical Research 17 ~50% Success rate Success Stories 16 Only 1 slam dunk Total 68 SuccessPendingActiveAll CasesStories Cases © 2019 Sarah Kladar Initial Challenge of Using Degraded DNA Question: Would genetic genealogy tools work for degraded samples? Joseph Newton Chandler III • DNA was degraded – 88% No calls • Nonuniform SNP Distribution Call Rate Call SNP Coordinate Initial Challenge - Degraded DNA • Experimented with Confidence Levels Call Rate Call SNP Coordinate High confidence: Few matches We found a happy medium We still use a three- kit model Low confidence: Many matches Initial Challenge - Degraded DNA • Degraded Our Own 23&Me data to match Chandler’s, compared matches before & after Rank on GEDmatch on After Rank GEDmatch Closest matches are the same rank Rank on GEDmatch Before Initial Challenge - Degraded DNA • Two 30x sequences ➔ One 60x -
Lesson Plan & Teacher's Guide
LESSON PLAN & TEACHER’S GUIDE DNA, Crime, and Law Enforcement Aim How will advances in DNA technology impact individuals, law enforcement and society? Time This lesson can be adjusted to fill 1 or 2 days. Guiding questions • How is scientific progress affecting how DNA is used to solve crimes in the United States? • What are the benefits and dilemmas of collecting DNA from people when they are arrested, but before they have been charged with a crime? • As a society, how should we balance privacy rights with the rights of crime victims? • How can DNA evidence be used to free innocent people? • How are different communities (within and outside your own) affected by the policies and procedures around DNA collection and law enforcement? Learning objectives By the end of this lesson, students will be able to: • Discuss why the number of people in DNA databases is on the rise. • Discuss the ethical issues surrounding the use of familial searching to solve crimes. • Analyze some of the controversies in using DNA to solve crimes. Personal Genetics Education Project (pgEd.org) 1 Rev. 2019 • Debate the issues around privacy, laws, freedom and public safety as they relate to DNA technology and crime. • Recognize some of the unintended consequences of how and why DNA is collected and used by law enforcement. Materials Projector or Smartboard, laptop, handouts. Standards alignment Common Core Standards CCSS.ELA-LITERACY.RH.9-10.6. CoMpare the point of view of two or More authors for how they treat the saMe or siMilar topics, including which details they include and eMphasize in their respective accounts. -
Genetic Genealogy and Its Use in Criminal Investigations: Are We Heading Towards a Universal Genetic Database?
Volume 15 Spring 2019 djim.management.dal.ca | Genetic Genealogy and its Use in Criminal Investigations: Are We Heading Towards a Universal Genetic Database? Emily Plemel School of Information Management, Dalhousie University Abstract In April 2018, Joseph DeAngelo also known as The Golden State Killer was caught and convicted. This was made possible by 40-year-old DNA evidence, genetic genealogy, and current information systems technology. This paper will discuss the history of genetic information such as DNA testing used in forensics, and consider information technologies effect on the future of criminal investigations. The main focus is genetic databases and their management. How will the management of these databases affect the public and law enforcement? Could a universal genetic database create solutions to the current criminal database systems, often critiqued for being discriminatory? How can we use genetic genealogy more efficiently to solve crimes? The sources used for this exploration include companies such as GEDmatch, 23andME, and Ancestry; key players of the field such as Barbara Rae Venter and CeCe Moore; newspaper articles, statistics, and academic journals. Keywords: DNA, genetic genealogy, cold-case, crime solving, forensic investigation, genetic database, information management, universal database 1 Lately, a small industry has been gaining and investigation process should be attention in the fields of criminal understood as follows. investigation and information management, The Procedure as it Currently that is, solving cold cases using genetic Stands genealogy and genetic information To explain the current process I will be databases. Already, there have been a few consulting information from Parabon key players identified in this growing field Nanolabs Inc., the company from which in North America; Cece Moore, Parabon CeCe Moore operates. -
Article I, Section 7, Law Enforcement, and Commercial DNA Databases
Washington Law Review Volume 95 Number 4 12-1-2020 The Thickness of Blood: Article I, Section 7, Law Enforcement, and Commercial DNA Databases Hannah Parman [email protected] Follow this and additional works at: https://digitalcommons.law.uw.edu/wlr Part of the Constitutional Law Commons, and the State and Local Government Law Commons Recommended Citation Hannah Parman, Comment, The Thickness of Blood: Article I, Section 7, Law Enforcement, and Commercial DNA Databases, 95 Wash. L. Rev. 2057 (2020). Available at: https://digitalcommons.law.uw.edu/wlr/vol95/iss4/10 This Comment is brought to you for free and open access by the Law Reviews and Journals at UW Law Digital Commons. It has been accepted for inclusion in Washington Law Review by an authorized editor of UW Law Digital Commons. For more information, please contact [email protected]. Parman (1) (Do Not Delete) 12/19/2020 6:01 PM THE THICKNESS OF BLOOD: ARTICLE I, SECTION 7, LAW ENFORCEMENT, AND COMMERCIAL DNA DATABASES Hannah Parman* Abstract: Law enforcement agencies increasingly use online commercial and open source DNA databases to identify suspects in cases that have long since gone cold. By uploading crime scene DNA to one of these websites, investigators can find family members who have used the website and build a family tree leading back to the owner of the original DNA. This is called “familial DNA searching.” The highest profile use of this investigative method to date occurred in California, but law enforcement in Washington State has been quick to begin utilizing the method as well. -
Genetic Privacy & the Fourth Amendment: Unregulated
GENETIC PRIVACY & THE FOURTH AMENDMENT: UNREGULATED SURREPTITIOUS DNA HARVESTING Albert E. Scherr* TABLE OF CONTENTS I. INTRODU CTION ................................................................... 447 II. THE TECHNOLOGY .............................................................. 450 III. THE COMMENTATORS AND THE CASES ................................ 453 IV. THE FOURTH AMENDMENT: BEYOND PROPERTY ................ 459 A. KATZ, KYLLO, AND JONES .............................................. 459 B. THE ABANDONMENT FALLACY ....................................... 465 C. THE OUT-OF-BODY FALLACY .......................................... 468 D. THE LIMITED-USE-OF-INFORMATION FALLACY ............... 471 V. "AN EXPECTATION OF GENETIC PRIVACY.... ................... 475 A. DIRECT FOURTH AMENDMENT GENETIC PRIVACY JURISPRUDENCE ............................................................ 478 B. CONCEPTUAL COMPONENTS OF GENETIC PRIVACY ........ 484 1. Physical Privacy ..................................................... 486 2. InformationalPrivacy ............................................ 492 a. Predictive .......................................................... 494 b. S hared ............................................................... 496 c. Personaland Intimate ...................................... 497 d. P ow erful ............................................................ 498 3. Dignitary Privacy ................................................... 504 Professor of Law, University of New Hampshire, School of Law. This Article -
DNA Hit of the Year 2019 Top 17 Cases
DNA Hit of the Year 2019 Top 17 Cases DNA Hit of the Year 2019 Top 17 Cases 1. Filipino housemaid found headless and handless in Dubai Country/State: Dubai - United Arab Emirates Year of Crime and Hit: 2016 and 2016 Executive Summary: A woman was found with her head and hands cut off. After 3 months of investigation Dubai poLice determined her identity by comparing her DNA to the personaL beLongings of a missing housemaid, a FiLipino woman named Manormeeta SaLwaro Dadi. The murder suspect’s DNA was obtained from the dead body. Investigations reveaLed the murderer may have been reLative. Police then profiled several of Dadi’s relatives and a match was found. The relative confessed when confronted. Scientific Importance: This woman was almost unidentifiable without a head and hands. Police cross-referenced the date and other details of this woman with active missing person cases throughout the country. This Led investigators to the house where she was a housemaid, Leading to DNA samples and a match. Investigative Importance: Dubai police had to sift through 9,751 missing women (runaway maids) cases to find leads for this particular case. Other: Murderer was a butcher who used his knowLedge and expertise as a butcher to cut off the head and hands of the victim. The murderer cLaimed that he was infLuenced by “zombie movies” to murder the victim in a such a way. Submitted Story: On 25 May 2016, a gruesome discovery was made of a decapitated female body with severed hands and stab wounds to the torso, road-side in a desert area in Dubai.