Syllabus for the Post of Assistant Professor, Infectious Disease, Class-I (Advt
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Gas Gangrene Infection of the Eyes and Orbits
Br J Ophthalmol: first published as 10.1136/bjo.69.2.143 on 1 February 1985. Downloaded from British Journal of Ophthalmology, 1985, 69, 143-148 Gas gangrene infection of the eyes and orbits GERARD W CROCK,' WILSON J HERIOT,' PATTABIRAMAN JANAKIRAMAN,' AND JOHN M WEINER2 From the 'Department of Ophthalmology, University ofMelbourne, and the2C H Greer Pathology Laboratory, the Royal Victorian Eye and Ear Hospital, East Melbourne, Australia SUMMARY The literature on Clostridium perfringens infections is reviewed up to 1983. An additional case is reported with bilateral clostridial infections of the eye and orbit. One eye followed the classical course of relentless panophthalmitis, amaurosis, and orbital cellulitis ending in enucleation. The second eye contained intracameral mud and gas bubbles that were removed by vitrectomy instrumentation. Subsequent removal of the toxic cataract resulted in a final aided visual acuity of 6/18, N8. This is the third report of a retained globe, and we believe the only known case where the patient was left with useful vision. Clostridium perfringens is a ubiquitous Gram- arms, chest, and abdomen. He was admitted to a positive bacillus found in soil and bowel flora. It is the general hospital, where he was examined under most common of four clostridia species identified in anaesthesia, and his injuries were attended to. copyright. cases of gas gangrene in man.' All species are obligate Ocular findings. The right cornea and anterior anaerobes and are usually saprophytic rather than chamber were intact. There was a scleral laceration pathogenic. Clostridium perfringens is a feared con- over the superonasal area of the pars plana with taminant of limb injuries and may result in death due vitreous prolapse. -
Kellie ID Emergencies.Pptx
4/24/11 ID Alert! recognizing rapidly fatal infections Susan M. Kellie, MD, MPH Professor of Medicine Division of Infectious Diseases, UNMSOM Hospital Epidemiologist UNMHSC and NMVAHCS Fever and…. Rash and altered mental status Rash Muscle pain Lymphadenopathy Hypotension Shortness of breath Recent travel Abdominal pain and diarrhea Case 1. The cross-country trucker A 30 year-old trucker driving from Oklahoma to California is hospitalized in Deming with fever and headache He is treated with broad-spectrum antibiotics, but deteriorates with obtundation, low platelet count, and a centrifugal petechial rash and is transferred to UNMH 1 4/24/11 What is your diagnosis? What is the differential diagnosis of fever and headache with petechial rash? (in the US) Tickborne rickettsioses ◦ RMSF Bacteria ◦ Neisseria meningitidis Key diagnosis in this case: “doxycycline deficiency” Key vector-borne rickettsioses treated with doxycycline: RMSF-case-fatality 5-10% ◦ Fever, nausea, vomiting, myalgia, anorexia and headache ◦ Maculopapular rash progresses to petechial after 2-4 days of fever ◦ Occasionally without rash Human granulocytotropic anaplasmosis (HGA): case-fatality<1% Human monocytotropic ehrlichiosis (HME): case fatality 2-3% 2 4/24/11 Lab clues in rickettsioses The total white blood cell (WBC) count is typicallynormal in patients with RMSF, but increased numbers of immature bands are generally observed. Thrombocytopenia, mild elevations in hepatic transaminases, and hyponatremia might be observed with RMSF whereas leukopenia -
Diagnostic Code Descriptions (ICD9)
INFECTIONS AND PARASITIC DISEASES INTESTINAL AND INFECTIOUS DISEASES (001 – 009.3) 001 CHOLERA 001.0 DUE TO VIBRIO CHOLERAE 001.1 DUE TO VIBRIO CHOLERAE EL TOR 001.9 UNSPECIFIED 002 TYPHOID AND PARATYPHOID FEVERS 002.0 TYPHOID FEVER 002.1 PARATYPHOID FEVER 'A' 002.2 PARATYPHOID FEVER 'B' 002.3 PARATYPHOID FEVER 'C' 002.9 PARATYPHOID FEVER, UNSPECIFIED 003 OTHER SALMONELLA INFECTIONS 003.0 SALMONELLA GASTROENTERITIS 003.1 SALMONELLA SEPTICAEMIA 003.2 LOCALIZED SALMONELLA INFECTIONS 003.8 OTHER 003.9 UNSPECIFIED 004 SHIGELLOSIS 004.0 SHIGELLA DYSENTERIAE 004.1 SHIGELLA FLEXNERI 004.2 SHIGELLA BOYDII 004.3 SHIGELLA SONNEI 004.8 OTHER 004.9 UNSPECIFIED 005 OTHER FOOD POISONING (BACTERIAL) 005.0 STAPHYLOCOCCAL FOOD POISONING 005.1 BOTULISM 005.2 FOOD POISONING DUE TO CLOSTRIDIUM PERFRINGENS (CL.WELCHII) 005.3 FOOD POISONING DUE TO OTHER CLOSTRIDIA 005.4 FOOD POISONING DUE TO VIBRIO PARAHAEMOLYTICUS 005.8 OTHER BACTERIAL FOOD POISONING 005.9 FOOD POISONING, UNSPECIFIED 006 AMOEBIASIS 006.0 ACUTE AMOEBIC DYSENTERY WITHOUT MENTION OF ABSCESS 006.1 CHRONIC INTESTINAL AMOEBIASIS WITHOUT MENTION OF ABSCESS 006.2 AMOEBIC NONDYSENTERIC COLITIS 006.3 AMOEBIC LIVER ABSCESS 006.4 AMOEBIC LUNG ABSCESS 006.5 AMOEBIC BRAIN ABSCESS 006.6 AMOEBIC SKIN ULCERATION 006.8 AMOEBIC INFECTION OF OTHER SITES 006.9 AMOEBIASIS, UNSPECIFIED 007 OTHER PROTOZOAL INTESTINAL DISEASES 007.0 BALANTIDIASIS 007.1 GIARDIASIS 007.2 COCCIDIOSIS 007.3 INTESTINAL TRICHOMONIASIS 007.8 OTHER PROTOZOAL INTESTINAL DISEASES 007.9 UNSPECIFIED 008 INTESTINAL INFECTIONS DUE TO OTHER ORGANISMS -
Cutaneous Melioidosis Dermatology Section
DOI: 10.7860/JCDR/2016/18823.8463 Case Report Cutaneous Melioidosis Dermatology Section BASAVAPRABHU ACHAPPA1, DEEPAK MADI2, K. VIDYALAKSHMI3 ABSTRACT Melioidosis is an emerging infection in India. It usually presents as pneumonia. Melioidosis presenting as cutaneous lesions is uncommon. We present a case of cutaneous melioidosis from Southern India. Cutaneous melioidosis can present as an ulcer, pustule or as crusted erythematous lesions. A 22-year-old gentleman known case of diabetes mellitus was admitted in our hospital with an ulcer over the left thigh. Discharge from the ulcer grew Burkholderia pseudomallei. He was successfully treated with ceftazidime. Melioidosis must be considered in the differential diagnosis of nodular or ulcerative cutaneous lesion in a diabetic patient. Keywords: B. pseudomallei, Diabetes Mellitus, Skin ulcer CASE REPORT melioidosis is a rare entity. Cutaneous melioidosis may be primary A 22-year-old gentleman was admitted in our hospital with (presenting symptom is skin infection) or secondary (melioidosis complaints of an ulcer over the left thigh of seven days duration. at other sites in the body with incidental skin involvement) [3]. History of fever was present for four days. He also complained of There is limited published data from India documenting cutaneous pain in the thigh. The patient initially noticed a nodule on the left melioidosis. thigh which eventually progressed to form a discharging ulcer. He B. pseudomallei reside in soil and water [4]. Inoculation, inhalation was a known case of diabetes mellitus (type 1) on insulin. Clinical or ingestion of infected food or water are the modes of transmission examination revealed a 5cm× 5cm ulcer on the left thigh with [5]. -
Necrotizing Fasciitis
INFORMATION ABOUT NECROTIZING FASCIITIS • Information has been circulating on social media/media outlets of an individual who developed an infection after visiting our area. We are taking this issue seriously and are working with the Indiana Department of Health to determine if this infection was caused by bacteria such as Vibrio vulnificus or other reportable disease. Currently, we do not have any information about this individual’s illness. • Necrotizing fasciitis (many times called “flesh eating bacteria” by the media) is caused by more than one type of bacteria. Several bacteria, common in our environment can cause this condition – the most common cause of necrotizing fasciitis is Group A strep. • People do not “catch” necrotizing fasciitis; it is a complication or symptom of a bacterial infection that has not been promptly or properly treated. • Sometimes people call Vibrio vulnificus the “flesh eating bacteria.” Vibrio vulnificus is a naturally occurring bacteria found in warm salty waters such as the Gulf of Mexico and surrounding bays. Concentrations of this bacteria are higher when the water is warmer. • Necrotizing fasciitis and severe infections with Vibrio vulnificus are rare. These infections can be treated with antibiotics and sometimes require surgery to remove damaged tissue. Rapid diagnosis is the key to effective treatment and recovery. • If you are healthy with a strong immune system, your chances of developing or having complications due to this condition are extremely low. HOW TO REDUCE YOUR RISK OF EXPOSURE • The Centers for Disease Control and Prevention (CDC) encourages all people to avoid open bodies of water (such as the Gulf), pools and hot tubs with breaks in the skin. -
WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/05 (2006.01) A61P 31/02 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/CA20 14/000 174 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 4 March 2014 (04.03.2014) KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (30) Priority Data: ZW. 13/790,91 1 8 March 2013 (08.03.2013) US (84) Designated States (unless otherwise indicated, for every (71) Applicant: LABORATOIRE M2 [CA/CA]; 4005-A, rue kind of regional protection available): ARIPO (BW, GH, de la Garlock, Sherbrooke, Quebec J1L 1W9 (CA). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: LEMIRE, Gaetan; 6505, rue de la fougere, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Sherbrooke, Quebec JIN 3W3 (CA). -
Staging of Necrotizing Fasciitis Based on the Evolving Cutaneous Features
ReportBlackwellOxford,IJDInternational0011-905945 UK Publishing Journal LtdLtd,of Dermatology 2006 StagingWang,Case report Wong, of necrotizing and Tay fascitis of necrotizing fasciitis based on the evolving cutaneous features Yi-Shi Wang, MBBS, MRCP, Chin-Ho Wong, MBBS, MRCS, and Yong-Kwang Tay, MBBS, FRCP From the Division of Dermatology, Changi Abstract General Hospital, Department of Plastic Background Necrotizing fasciitis is a severe soft-tissue infection characterized by a fulminant Reconstructive and Aesthetic Surgery, course and high mortality. Early recognition is difficult as the disease is often clinically Singapore General Hospital, Singapore indistinguishable from cellulitis and other soft-tissue infections early in its evolution. Our aim was Correspondence to study the manifestations of the cutaneous signs of necrotizing fasciitis as the disease evolves. Yi-Shi Wang, MBBS, MRCP Methods This was a retrospective study on patients with necrotizing fasciitis at a single Division of Dermatology institution. Their charts were reviewed to document the daily cutaneous changes from the time Changi General Hospital of presentation (day 0) through to day 4 from presentation. 2 Simei Street 3 Singapore 529889 Results Twenty-two patients were identified. At initial assessment (day 0), almost all patients E-mail: [email protected] presented with erythema, tenderness, warm skin, and swelling. Blistering occurred in 41% of patients at presentation whereas late signs such as skin crepitus, necrosis, and anesthesia Presented at the European Academy of were infrequently seen (0–5%). As time elapsed, more patients had blistering (77% had blisters Dermatology and Venereology (EADV) 14th at day 4) and eventually the late signs of necrotizing fasciitis characterized by skin crepitus, Congress, London, October 12 to 16, 2005. -
Reportable Disease Surveillance in Virginia, 2013
Reportable Disease Surveillance in Virginia, 2013 Marissa J. Levine, MD, MPH State Health Commissioner Report Production Team: Division of Surveillance and Investigation, Division of Disease Prevention, Division of Environmental Epidemiology, and Division of Immunization Virginia Department of Health Post Office Box 2448 Richmond, Virginia 23218 www.vdh.virginia.gov ACKNOWLEDGEMENT In addition to the employees of the work units listed below, the Office of Epidemiology would like to acknowledge the contributions of all those engaged in disease surveillance and control activities across the state throughout the year. We appreciate the commitment to public health of all epidemiology staff in local and district health departments and the Regional and Central Offices, as well as the conscientious work of nurses, environmental health specialists, infection preventionists, physicians, laboratory staff, and administrators. These persons report or manage disease surveillance data on an ongoing basis and diligently strive to control morbidity in Virginia. This report would not be possible without the efforts of all those who collect and follow up on morbidity reports. Divisions in the Virginia Department of Health Office of Epidemiology Disease Prevention Telephone: 804-864-7964 Environmental Epidemiology Telephone: 804-864-8182 Immunization Telephone: 804-864-8055 Surveillance and Investigation Telephone: 804-864-8141 TABLE OF CONTENTS INTRODUCTION Introduction ......................................................................................................................................1 -
HIV (Human Immunodeficiency Virus)
TABLE OF CONTENTS AFRICAN TICK BITE FEVER .........................................................................................3 AMEBIASIS .....................................................................................................................4 ANTHRAX .......................................................................................................................5 ASEPTIC MENINGITIS ...................................................................................................6 BACTERIAL MENINGITIS, OTHER ................................................................................7 BOTULISM, FOODBORNE .............................................................................................8 BOTULISM, INFANT .......................................................................................................9 BOTULISM, WOUND .................................................................................................... 10 BOTULISM, OTHER ...................................................................................................... 11 BRUCELLOSIS ............................................................................................................. 12 CAMPYLOBACTERIOSIS ............................................................................................. 13 CHANCROID ................................................................................................................. 14 CHLAMYDIA TRACHOMATIS INFECTION ................................................................. -
Early History of Infectious Disease
© Jones and Bartlett Publishers. NOT FOR SALE OR DISTRIBUTION CHAPTER ONE EARLY HISTORY OF INFECTIOUS 1 DISEASE Kenrad E. Nelson, Carolyn F. Williams Epidemics of infectious diseases have been documented throughout history. In ancient Greece and Egypt accounts describe epidemics of smallpox, leprosy, tuberculosis, meningococcal infections, and diphtheria.1 The morbidity and mortality of infectious diseases profoundly shaped politics, commerce, and culture. In epidemics, none were spared. Smallpox likely disfigured and killed Ramses V in 1157 BCE, although his mummy has a significant head wound as well.2 At times political upheavals exasperated the spread of disease. The Spartan wars caused massive dislocation of Greeks into Athens triggering the Athens epidemic of 430–427 BCE that killed up to one half of the population of ancient Athens.3 Thucydides’ vivid descriptions of this epidemic make clear its political and cultural impact, as well as the clinical details of the epidemic.4 Several modern epidemiologists have hypothesized on the causative agent. Langmuir et al.,5 favor a combined influenza and toxin-producing staphylococcus epidemic, while Morrens and Chu suggest Rift Valley Fever.6 A third researcher, Holladay believes the agent no longer exists.7 From the earliest times, man has sought to understand the natural forces and risk factors affecting the patterns of illness and death in society. These theories have evolved as our understanding of the natural world has advanced, sometimes slowly, sometimes, when there are profound break- throughs, with incredible speed. Remarkably, advances in knowledge and changes in theory have not always proceeded in synchrony. Although wrong theories or knowledge have hindered advances in understanding, there are also examples of great creativity when scientists have successfully pursued their theories beyond the knowledge of the time. -
Louisiana Morbidity Report
Louisiana Morbidity Report Office of Public Health - Infectious Disease Epidemiology Section P.O. Box 60630, New Orleans, LA 70160 - Phone: (504) 568-8313 www.dhh.louisiana.gov/LMR Infectious Disease Epidemiology Main Webpage BOBBY JINDAL KATHY KLIEBERT GOVERNOR www.infectiousdisease.dhh.louisiana.gov SECRETARY September - October, 2015 Volume 26, Number 5 Cutaneous Leishmaniasis - An Emerging Imported Infection Louisiana, 2015 Benjamin Munley, MPH; Angie Orellana, MPH; Christine Scott-Waldron, MSPH In the summer of 2015, a total of 3 cases of cutaneous leish- and the species was found to be L. panamensis, one of the 4 main maniasis, all male, were reported to the Department of Health species associated with progression to metastasized mucosal and Hospitals’ (DHH) Louisiana Office of Public Health (OPH). leishmaniasis in some instances. The first 2 cases to be reported were newly acquired, a 17-year- The third case to be reported in the summer of 2015 was from old male and his father, a 49-year-old male. Both had traveled to an Australian resident with an extensive travel history prior to Costa Rica approximately 2 months prior to their initial medical developing the skin lesion, although exact travel history could not consultation, and although they noticed bug bites after the trip, be confirmed. The case presented with a non-healing skin ulcer they did not notice any flies while traveling. It is not known less than 1 cm in diameter on his right leg. The ulcer had been where transmission of the parasite occurred while in Costa Rica, present for 18 months and had not previously been treated. -
Communicable Disease Case Counts 2014-2018
Report 4: Table of Diseases Comparing A Given Timeframe for Past 5 Years Case Types: Individual Cases Only Case Status: Confirmed, Probable Year: 2014-2018 Investigation Status: Completed Display Interval: By Year Jurisdictions: Mid-Michigan District Report Type: Counts Disease Group Disease 2014 2015 2016 2017 2018 Total AIDS/HIV AIDS, Aggregate 0 0 0 0 0 0 HIV/AIDS, Adult 3 2 0 0 0 5 HIV/AIDS, Pediatric 0 0 0 0 0 0 Subtotal 3 2 0 0 0 5 Foodborne Amebiasis 1 0 0 1 0 2 Botulism - Foodborne 0 0 0 0 0 0 Campylobacter 14 31 17 20 12 94 Cryptosporidiosis 7 6 13 15 7 48 Escherichia coli 0157:H7 (Pre-2011)* 0 0 0 0 0 0 Giardiasis 19 10 8 14 3 54 Listeriosis 0 0 0 0 0 0 Listeriosis (2014- 2017)* 1 0 0 0 0 1 Listeriosis (Pre-2014)* 0 0 0 0 0 0 Norovirus 4 1 13 7 5 30 Paratyphoid Fever 0 0 0 0 0 0 Salmonellosis 10 12 24 20 20 86 Shiga toxin, E. Coli, Non O157 (Pre- 2011)* 0 0 0 0 0 0 Shiga toxin, E. Coli, Unsp (Pre-2011)* 0 0 0 0 0 0 Shiga toxin-producing Escherichia coli -- (STEC) 4 1 4 0 3 12 Shigellosis 3 5 13 5 2 28 Typhoid Fever 0 0 0 0 0 0 Yersinia enteritis 0 1 1 0 0 2 Subtotal 63 67 93 82 52 357 Influenza Flu Like Disease* 0 0 0 0 0 0 Influenza 37 63 49 231 278 658 Influenza, 2009 Novel* 0 0 0 0 0 0 Influenza, Novel 0 0 0 0 0 0 Subtotal 37 63 49 231 278 658 Meningitis Meningitis - Aseptic 6 21 11 9 13 60 Meningitis - Bacterial Other 1 3 2 3 7 16 Meningococcal Disease 0 1 0 0 0 1 Streptococcus pneumoniae, Inv 8 20 25 20 24 97 Subtotal 15 45 38 32 44 174 01-17-2019 1 of 5 Disease Group Disease 2014 2015 2016 2017 2018 Total Other Acute Flaccid