6 Chemical Skin Burns
53 6 Chemical Skin Burns Magnus Bruze, Birgitta Gruvberger, Sigfrid Fregert Contents aged to a point where there is no return to viability; in other words, a necrosis develops [7, 43, 45]. One 6.1 Introduction . 53 single skin exposure to certain chemicals can result 6.2 Definition . 53 in a chemical burn. These chemicals react with intra- 6.3 Diagnosis . 56 and intercellular components in the skin. However, 6.4 Clinical Features . 56 the action of toxic (irritant) chemicals varies caus- 6.5 Treatment . 57 ing partly different irritant reactions morphologically. 6.6 Complications . 58 They can damage the horny layer, cell membranes, 6.7 Prevention . 59 6.8 Summary . 59 lysosomes, mast cells, leukocytes, DNA synthesis, References . 60 blood vessels, enzyme systems, and metabolism. The corrosive action of chemicals depends on their chem- ical properties, concentration, pH, alkalinity, acidity, temperature, lipid/water solubility, interaction with 6.1 Introduction other substances, and duration and type (for exam- ple, occlusion) of skin contact. It also depends on the Chemical skin burns are particularly common in in- body region, previous skin damage, and possibly on dustry, but they also occur in non-work-related en- individual resistance capacity. vironments. Occupationally induced chemical burns Many substances cause chemical burns only when are frequently noticed when visiting and examining they are applied under occlusion from, for example, workers at their work sites. Corrosive chemicals used gloves, boots, shoes, clothes, caps, face masks, ad- in hobbies are an increasing cause of skin burns. Dis- hesive plasters, and rings. Skin folds may be formed infectants and cleansers are examples of household and act occlusively in certain body regions, e.g., un- products which can cause chemical burns.
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