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LUNGWORM

Cattle suffer lungworm infestations with viviparus. Infective larvae on pasture are ingested and then migrate from gut to lung, where the adult population resides. Adults produce larvae, which are passed out in faeces (when coughed up and swallowed).

Larvae develop into adults in the larger air spaces in the lungs. The time from infection to the presence of adult, egg-laying worms in the airways is around 3 to 4 weeks

Larvae penetrate the intestine wall and migrate to IN THE COW The lungworm eggs hatch in the lungs in the blood the lungs. Thousands of microscopic larvae may be coughed up and swallowed Young eat by the animal contaminated grass

Immature larvae move The final-stage infective through the gut, passing out larvae are spread widely in the dung onto pasture, onto the pasture, largely by Lungworm larvae Lungworm larvae ON THE where they develop and the action of a fungus which can stimulate an penetrate the become infective immune reaction intestine to travel grows in dung pats PASTURE in a few days when they penetrate to the lungs via the intestine and are the blood stream killed by injectable or pour-on wormers

DEC JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV

Disease (commonly called husk) is classically seen in young stock from July to October, approximately 4 months after turnout to pasture, although disease may not be noted until the cattle are housed. Early clinical signs include an increased respiratory rate at rest, but more noticeably, frequent coughing, especially after short periods of exercise. In the dairy herd, infection of susceptible cattle results in a dramatic reduction in milk yield of up to 50%, with possible deaths. Frequent coughing is noted when cows are walking to and from the milking parlour. Disease prevention is based upon stimulating the development of immunity, by either vaccination with an attenuated lungworm vaccine, or by ensuring periods of controlled natural exposure/infection through strategic anthelmintic interventions.

FOR ANIMALS. FOR HEALTH. FOR YOU. TREATMENT OPTIONS

Zoetis Cattle 5ml Injection Admin Pack

CYDECTIN 10% LA Solution for Injection for Cattle • Season-long worm control • Dose is weight related • Season long satisfaction guarantee • Opportunity for natural immune response to lungworm and gut worm

Zoetis Cattle Bolus Applicator

Autoworm • Suitable for use with Autoworm • Season-long protection Finisher/First Grazer • Opportunity for natural immune response to lungworm and gut worms • Broad spectrum worm control including tapeworms

Zoetis Cattle 70ml Pour-on Applicator

CYDECTIN 0.5% Pour-On for Cattle • 70ml pour-on applicator • The longest dosing interval against key • Variable dosing 1 cattle worms of any pour-on • Tubing with anti-kink springs • Convenient and rain-fast application • Minimal impact on dung beetles2 • With a lice-free guarantee from housing to turnout3

triclabendazole Zoetis Cattle 70ml Fluke and Worm Pour-On for Cattle Pour-on Applicator

CYDECTIN TriclaMox Pour-On Solution for Cattle • 70ml pour-on applicator • Contains moxidectin • Variable dosing • Contains triclabendazole, established as the fl ukicide with • Tubing with anti-kink springs activity against the widest range of fl uke maturity • Kills liver fl uke and roundworms in a single treatment • Easy to use and effective, saving time and cost

1. Against Ostertagia spp. and Dictyocaulus spp 2. Floate et al., (2002): Bulletin of Entomological Research, 92, 471-481 3. Conditions apply. See Lice-Free Guarantee leafl et for full details

Product infrormation: CYDECTIN 10% LA SOLUTION FOR INJECTION FOR CATTLE contains moxidectin. For the treatment and prevention of mixed infections of gastrointestinal , respiratory nematodes and certain arthropod parasites in cattle. POM-VPS 3-ML AUTOWORM FIRST GRAZER/FINISHER contains oxfendazole. For the treatment of adult/ immature gastrointestinal roundworms, lungworms and tapeworms in grazing cattle during their fi rst and second grazing season, respectively. POM-VPS 1-BZ CYDECTIN 0.5% W/V POUR-ON FOR CATTLE contains moxidectin. For the treatment and prevention of infections caused by parasites sensitive to moxidectin. POM-VPS 3-ML CYDECTIN TRICLAMOX 5 MG/ ML + 200 MG/ML POUR-ON SOLUTION FOR CATTLE contains moxidectin and triclabendazole. For the treatment of mixed and fl uke infections, and certain arthropod infestations caused by moxidectin and triclabendazole sensitive parasites. POM-VPS 3-ML For further information please see the product’s SPC or contact Zoetis UK Limited, Walton Oaks, Dorking Road, Tadworth, Surrey KT20 7NS. www.zoetis.co.uk. Customer Support: 0845 300 8034. Use medicines responsibly (www.noah.co.uk/responsible). Date of preparation: April 2016 AH102/16