Immunohistochemistry Reference Guide, Vol
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Immunohistochemistry reference guide, vol. 10 New Products CD71 (MRQ-48) Androgen Receptor (SP107) . 13 CD23 (MRQ-57) . 46 Arginase-1 (SP156) . 15 CD23 (SP23) . 46 BCL2 (SP66) . 18 CD33 (PWS44) . 50 BCL6 (SP155) . 19 CD38 (SP149) . 53 BOB.1 (SP92) . 22 CD43 (SP55) . 54 C3d (polyclonal) . 23 CD56 (MRQ-42) . 59 C4d (SP91) . 24 CD71 (MRQ-48) . 64 Calcitonin (SP17) . 27 CD79a (SP18) . 66 Calretinin (SP13) . 30 CD99 (SP119) . 67 Carbonic Anhydrase IX (CA IX) CD138 (SP152) . 69 (MRQ-54 (also known as M75)) . 31 CMV (8B1 .2, 1G5 .2 & 2D4 .2) . 75 CD1a (EP3622‡) . 32 Cytokeratin 14 (SP53) . 86 CD3 (MRQ-39) . 34 Diamond TBS Antibody Diluent . 231 CD7 (MRQ-56) . 37 Epstein-Barr Virus (MRQ-47) . 99 CD8 (SP16) . 38 FoxP1 (SP133) . .105 CD11c (5D11) . 40 Hemoglobin A (EPR3608‡) . 119 CD20 (SP32) . 44 Her2/Neu (SP3) . 123 S100P (16/f5) Herpes Simplex Virus I (10A3) . 124 Progesterone Receptor (SP42) . 192 HGAL (MRQ-49) . 126 S100P (16/f5) . 199 IgG4 (MRQ-44) . 134 Smoothelin (R4A) . .200 KBA.62 . 140 SOX-2 (SP76) . 202 LMO2 (SP51) . 145 SOX-11 (MRQ-58) . 203 MSH6 (SP93) . 155 Synaptophysin (MRQ-40) . .206 MUM1 (MRQ-43) . 160 T-bet (MRQ-46) . 207 Myeloperoxidase (SP72) . .162 TBS IHC Wash Buffer + Tween® 20 . 231 Napsin A (MRQ-60) . 166 TdT (SP150) . 210 NSE (MRQ-55) . 169 TFE3 (MRQ-37) . 211 p53 (SP5) . .174 Thyroglobulin (MRQ-41) . .213 PAX-8 (MRQ-50) . .182 TIA-1 (EP243‡) . .214 PAX-8 (polyclonal) . .182 Uroplakin III (SP73) . 221 PBS IHC Wash Buffer + Tween® 20 . 231 Varicella Zoster Virus (multiple clones) . 222 Phosphohistone H3 (PHH3) (polyclonal) . 186 Vimentin (SP20) . 224 PMS2 (EPR3947‡) . 188 PNL2 . .190 Cell Marque Immunohistochemistry Reference Guide Vol . 10 Rev . 0 .10 ii Table of ABOUT CELL MARQUE Cell Marque Leadership . 2 Our Mission . 2 Our Vision and Values .. 2 Contents Phosphohistone H3 (PHH3) (polyclonal) PRODUCTS New Products . Inside Front Cover Antibodies . 3 Companion Products . .227 HiDef Detection™ Systems . .228 Detection Systems & Chromogens .. 229 Trilogy™ . .230 Declere™ . .231 Pretreatment Reagents, Ancillary Reagents, & Hardware . 231 SCIENTIFIC, TECHNICAL, & REFERENCE Categorical Listing of Antibodies . 4 Troubleshooting . .232 Product Index . .234 Disclaimers . 235 Ordering Information . 236 From Passion to Product to Patient.® TFE3 (MRQ-37) Cell Marque Immunohistochemistry Reference Guide Vol . 10 Rev . 0 .10 1 Leadership With each passing year, I’m excited to share with you our dedication to excellence and our passion for state-of-the-art IHC reagents and services. I truly believe Cell Marque’s success not only comes from the energy of our organization, but also as a result of the symbiosis achieved through our relationships with external customers, our vendors, our business partners, and our consultants. It is you, our customers, and of course the patients you serve, that give true meaning to the concerted effort needed “to make it all happen.” I am proud to be the owner and President of such a company, and it is through the culture we have cultivated at Cell Marque that I am confident to say that every year will top the year previous. I am fortunate Executive Team (left to right)- Michael Lacey, M.D., Medical Director & Pathologist; to work alongside some of the brightest and most educated Nora Lacey, President & CEO; S. Carlos Del Buono, Vice-President Operations; Sarah Aghassi, Esq., Vice-President Legal Affairs; David Zembo, E.A., Chief Financial professionals in our industry, and I extend my gratitude to all Officer; Veronica Runyan, Vice-President Regulatory & Quality Affairs; Mark Corl, involved. – Nora Lacey, President & CEO Vice-President Sales & Marketing; Paul Ardi, Senior Vice-President Our Mission Our world class team strives to be the leading supplier of advanced histopathology reagents through a culture of innovation, continuous improvement, and relentless dedication to both those we serve and perfection of the art. Our Vision and Values Customer: In all we do, we are dedicated to exceeding the expectations of our customers. Employee: We empower and equip our employees to make our brand the most trusted and sought after in our industry. Leadership: We cultivate organizational synergy in the pursuit of excellence. Loyalty: We promote brand loyalty by delivering exceptional value and distinguished service. Market Share: We will be first in the mind of the customer. Alliance: We foster mutually beneficial relationships with global strategic partners. Research: We commit resources to continually identify and offer products to further advance the art of histopathology. Quality: We believe that service to the customer begins with quality. Universal: We serve the healthcare needs of the global community through universal applications of our products. Execution: From Passion to Product to Patient.® 2 Cell Marque Immunohistochemistry Reference Guide Vol . 10 Rev . 0 .10 2 Antibodies Color Microscopy- 2010, oil on canvas Cell Marque Immunohistochemistry Reference Guide Vol . 10 Rev . 0 .10 3 Categorical Quick Reference Fellow Pathologists, It is, of course, you who carry the responsibility of Cytokeratin 14 . 86 Harmony™ Cocktails properly applying and interpreting the results of the Cytokeratin 17 . 87 Cytokeratin 5 + Cytokeratin 14 . 16 Cytokeratin 19 . 88 tests utilizing the products found in this catalog. We Cytokeratin 5 & 6 + TTF-1 . 146 Cytokeratin 20 . 89 HMB-45 + MART-1 (Melan A) + Tyrosinase . 151 have attempted to make it the most useful, practical, Cytokeratin Cocktail (AE1 & AE3) . 90 and informative catalog to date. There are many new Cytokeratin, HMW . 91 products, the applicable literature for which, may Cytokeratin, LMW . 92 Hematolymphoid Markers have been limited at the time of publication. Please E-cadherin .. 95 EMA . 96 A-1-Antichymotrypsin . .6 keep this in mind when reviewing the material herein. Ep-CAM (Ber-EP4). 97 A-1-Antitrypsin . .7 It is my goal to present current information, and yet Ep-CAM (MOC-31) . 98 ALK Protein . 11 maintain a conservative approach keeping in mind GCDFP-15 . 109 Annexin A1 . 14 that the perceived utility of primary antibodies may GLUT1 . 113 BCL2 . 18 Glypican-3 . 115 BCL6 . 19 change to a certain degree with time and experience. Human Placental Lactogen (hPL) . 130 BOB .1 .. 22 Having said this, I hope you find the pages herein Inhibin, alpha . 136 CD1a . 32 useful in your practice as a quick reference, as it is Ksp-cadherin . 142 CD2 . 33 hard to overstate the importance of the application Mammaglobin . 149 CD3 . 34 CD4 . 35 of these tools in the current practice of pathology. MUC1 . 156 MUC2 . 157 CD5 . 36 MUC5AC . 158 CD7 . 37 MUC6 . 159 CD8 . 38 Napsin A . 166 CD10 . 39 Nerve Growth Factor Receptor (NGFR) . 167 CD11c . 40 Michael G. Lacey, MD, Medical Director p120 Catenin . 176 CD14 . 41 P504s. 177 CD15 . 42 PAX-2 . 180 CD19 . 43 PAX-8 . 182 CD20 . 44 Breast Markers Renal Cell Carcinoma . 197 CD21 . 45 Estrogen Receptor (ER) . 100 S100P . 199 CD23 . 46 Her2/Neu (c-erbB-2) . 123 SOX-2 . 202 CD25 . 47 Progesterone Receptor (PR) . 192 TAG-72 . 208 CD30 (Ki-1) . 48 TFE3 . 211 CD31 . ..